Products

4-(2-Hydroxyethyl)Piperazine-1-Ethanesulfonic Acid Sodium Salt

Lingxian Chemical

Specifications

HS Code

296786

Chemical Formula C8H17N2NaO6S
Molecular Weight 292.28
Appearance White to off - white powder
Solubility Soluble in water
Ph Range 6.8 - 8.2 (effective buffer range)
Pka Value 7.55 (at 25°C)
Melting Point Typically around 230 - 235°C
Stability Stable under normal conditions
Hygroscopicity May be slightly hygroscopic
Cas Number 71119 - 23 - 8
Packing & Storage
Packing Package contains 500 g of 4-(2-Hydroxyethyl)Piperazine - 1 - Ethanesulfonic Acid Sodium Salt.
Storage Store 4-(2 - Hydroxyethyl)Piperazine - 1 - Ethanesulfonic Acid Sodium Salt in a cool, dry place. Keep it away from heat sources and direct sunlight as elevated temperatures can affect its stability. Store in a tightly - sealed container to prevent moisture absorption and contamination from the surrounding environment.
Shipping 4-(2-Hydroxyethyl)Piperazine-1-Ethanesulfonic Acid Sodium Salt is typically shipped in sealed, corrosion - resistant containers. It's packaged to prevent moisture ingress and damage during transit, adhering to chemical transportation safety regulations.
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4-(2-Hydroxyethyl)Piperazine-1-Ethanesulfonic Acid Sodium Salt
General Information
Historical Development
The sodium salt of Fu 4- (2-hydroxyethyl) piperazine-1-ethanesulfonate is actually one of the chemical substances. In the past, it was first noticed by many sages, when the exploration of chemistry was in the ascendant. Researchers have tried their best to understand its nature and its use.
At first, only a few or two characteristics were known about it. With the passage of time, the research deepened, and the cognition of its structure and properties became clearer. Its use in many fields has also been observed by the academic community. From laboratory micro-tests to industrial applications, it is all involved. The road of exploration in the past, despite many hardships, was determined by scholars, which eventually led to the use of this compound in the world, adding a touch of brilliance to the development of chemistry and becoming a good proof of past research.
Product Overview
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, this is a delicate chemical substance. It has a unique structure, derived from piperazine ring, and its side chain is connected with hydroxyethyl group and ethanesulfonate group, and it forms a sodium salt state.
This substance has a wide range of uses in many fields such as biochemical research. Because of its good buffering performance, it can maintain the stability of the pH of the system within a specific pH range. In the research experiments of biological macromolecules such as proteins and enzymes, it can create a suitable acid-base environment to ensure the activity and structural stability of biomolecules, so that the research can be carried out smoothly. It is an indispensable and important material in the field of biochemical research and has made significant contributions to the progress of scientific research.
Physical & Chemical Properties
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, its physicochemical properties are related to many aspects. Looking at its shape, it is often a white crystalline powder, which is observable by the eye. In terms of its solubility, it is soluble in water, just like salt mixed into soup, homogeneous, this is its characteristic in the liquid phase. Its stability is good, under normal temperature, it can maintain its inherent state, not easy to change. And it has a certain pH buffering ability, like a gentle guardian, guarding the acid-base balance of the system. These are the important physicochemical properties of 4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, which are crucial in many fields.
Technical Specifications & Labeling
The sodium salt of 4- (2-hydroxyethyl) piperazine-1-ethanesulfonate is one of the kinds involved in the research of chemical products. Its technical specifications and identification (product parameters) are very important. The properties of this product need to be carefully examined to observe its color and state, and to check whether it has variegated colors or foreign bodies. The measurement of purity is a priority, and it is related to its quality. It must be measured accurately to ensure compliance. Its solubility varies in different solvents and needs to be carefully investigated. On the logo, the name must be accurate, indicating the chemical name and common name, and the relevant parameters, such as molecular weight, molecular formula, etc., should be clearly marked so that the user can see it at a glance, so that it can be properly applied in various fields of scientific research and production without error.
Preparation Method
To prepare 4 - (2 - hydroxyethyl) piperazine - 1 - ethanesulfonate sodium salt, the method is as follows: Prepare the raw materials first, and obtain an appropriate amount of piperazine, sodium hydroxyethyl sulfonate, etc. In a clean vessel, control the temperature to an appropriate value, start with piperazine and hydroxyethyl sulfonate in the solvent, and stir it slowly. The progress of temperature change and response should be carefully observed to prevent deviations. After the application is completed, the separation method, such as filtration, distillation, etc., removes impurities and stores sperm. Complex with alkali to adjust the pH to make a sodium salt. After crystallization and drying, pure 4 - (2 - hydroxyethyl) piperazine - 1 - ethanesulfonate sodium salt is obtained. Every step requires following the procedures to ensure the quality of the product.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance 4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt. We are chemical researchers who often study the chemical reaction and modification of the substance. This salt also has unique properties in many reaction systems.
When it participates in the reaction, it can cause different chemical changes due to the hydroxyethyl group, piperazine, and ethanesulfonate radical groups. Or nucleophilic substitution with nucleophiles, the hydroxyl group is active and easy to react.
In terms of modification, it can be modified by a group to change its solubility and stability. If a hydrophobic group is introduced, its interfacial activity can be changed. And this salt has application in biological buffer system. Modification can optimize buffer performance and make it more suitable for specific environment, which is beneficial to biological experiments and industrial production. We should further study the reaction and modification of this salt to expand its use.
Synonyms & Product Names
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, its synonymous name and the name of the product, are all known to our researchers. The name of the husband is the consensus of the academic community, used to accurately express the meaning, so that colleagues are correct in communication. The name of the product is related to the promotion of the market, often easy to remember and can recognize its characteristics.
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, or another name, is due to the chemical industry, different regions and schools, and different considerations when naming. However, its essence is the same, all are this specific compound. The name of the product, the merchant in order to make the product stand out, in line with market demand, or take a concise and clear word, or give a unique meaning, hoping to win the favor of users.
We study this substance, in the name of the synonym and the name of the product, need to be carefully examined. To understand the name of the synonym can be connected to the academic context; to know the name of the product, we can know the dynamics of the market. The two complement each other and are of great significance to chemical research and industrial development.
Safety & Operational Standards
4 - (2 - hydroxyethyl) piperazine - 1 - ethanesulfonate sodium salt, this is a chemical substance. It is extremely important for its safety and operating standards.
It is mild in nature, but it is still necessary to follow the procedures when operating. Operate in a well-ventilated place to avoid contact with the skin and eyes. If you accidentally touch the skin, rinse quickly with plenty of water; if it splashes into the eyes, rinse with running water immediately and seek medical treatment.
Storage is also particular, and it should be placed in a cool, dry place, away from sources of fire and incompatible objects. When taking it, be sure to use clean utensils, operate according to the exact amount, and do not increase or decrease at will.
Furthermore, during the operation, it is necessary to pay attention to the surrounding environment and do not allow it to spread and cause environmental pollution. If there is any spill, it should be cleaned up immediately according to specific methods to ensure safety.
Although this chemical substance has a wide range of uses, only by strictly observing safety and operating standards can it avoid accidents, achieve the expected effect, and ensure the safety of the operator and the environment.
Application Area
In today's world, there is a product called "4- (2 -Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt". This product is widely used in the field of biochemistry.
In the field of medical treatment and cell cultivation, this product can stabilize the acid and base of the environment and ensure the safe growth of cells. It makes cells in a balanced state and is not disturbed by acid-base upheavals, which is very powerful.
In the process of scientific research, the analysis of enzymes also depends on this product. The acid-base conditions of controlled reactions make the enzyme's properties clear, the reaction is smooth, and the results can be tested.
In the pharmaceutical research industry, the preparation process, this product is also indispensable. To help the stability of the drug, to ensure its constant effect, as a good supplement to the drug.
From this point of view, "4- (2 -Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt" is very useful in various application fields, and it is actually an important material for biochemical research.
Research & Development
In modern times, chemistry has flourished, and material research has become increasingly prosperous. Today, there is a sodium salt of 4- (2-hydroxyethyl) piperazine-1-ethanesulfonate, which is widely used in scientific research. We devote ourselves to our research to explore its properties, investigate its sources, and expand its uses.
At the beginning, analyze its structure, explain its molecular structure, atomic connection, and understand why it is. The second time to explore its properties, in different temperatures, pressures, and liquids, observe its reaction, change its state, and know its physicochemical properties.
Then think about its application, in the field of biochemistry, it can be used as a buffering agent to stabilize the environment of acid and alkali; in the road of medicine, or to assist the research of drugs, to increase the effectiveness of drugs.
Our generation should make unremitting efforts to study this object, hoping to create new methods and expand new applications, and make every effort for the progress of chemistry and the development of science and technology.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons is also essential. Today there is a product called "4- (2-Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt", and the study of its toxicity should not be underestimated.
To study the toxicity of this product, it is necessary to use a scientific method to observe its impact on organisms under different environments and doses. To observe its interaction with the body, whether there are abnormal changes, such as damage to physiological functions and the appearance of pathological manifestations.
A detailed study of toxicity can clarify its harm and fortify for production and use. Or set safety limits, or find protective measures, so that although this chemical is useful, it will not hurt people. The study of poisons is to ensure people's safety and protect the environment, which is the heavy responsibility of our generation of chemical researchers.
Future Prospects
I am researching the product of 4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt. This product is in the field of biochemistry and has a wide range of uses. It can stabilize the acid and base of the system and help all kinds of experiments to be accurate.
Looking at its future, it is expected to be exhibited in more scientific research branches. In medical research, it may be able to stabilize the cell culture environment and promote cell growth research; in drug development, it may become a key excipient to help the drug stabilize and dissolve.
And technology is changing, and the preparation process should also be optimized. The cost may be reduced, the quality is better, and this product is more accessible to all researchers. Its future scene, like the dawn, full of hope, will surely be able to shine on the road of scientific research, and the academic aid community will reach a new height.
Frequently Asked Questions
What is the use of 4- (2 - Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, commonly known as HEPES sodium salt, is widely used in the field of biochemical research.
Its primary use is as a biological buffer. During cell culture, cells are extremely sensitive to the pH of the environment in which they are located, and subtle pH changes may affect cell growth, metabolism and even survival. HEPES sodium salt has excellent buffering ability and can stabilize the pH value of cell culture medium within a specific range, usually between pH 6.8 and 8.2, allowing cells to grow normally in a suitable pH environment. If mammalian cells are cultured and the pH is maintained at 7.2-7.4, HEPES sodium salt can play a key role in ensuring the stability of the cell microenvironment.
This salt is also indispensable in the enzymatic reaction system. Many enzymes have the best activity only under specific pH conditions, and HEPES sodium salt can create and maintain this suitable pH environment, so that the enzyme can efficiently catalyze the reaction. For example, in the proteolysis reaction involving some proteases, the HEPES sodium salt buffer system can ensure that the enzyme activity is at a high level and promote the smooth progress of the reaction.
In addition, in the study of protein crystallization, suitable pH conditions are essential to obtain high-quality protein crystals. HEPES sodium salt can effectively adjust the pH value of the crystallization solution, assist researchers in obtaining ideal protein crystals, facilitate the use of X-ray crystallography and other techniques to analyze the three-dimensional structure of proteins, and enhance the understanding of protein functions and mechanisms of action.
Furthermore, in molecular biology experiments, such as nucleic acid extraction, PCR amplification, etc., a stable pH environment is also the key to the success of the experiment. HEPES sodium salt can regulate the pH of the reaction system, ensure the stability of nucleic acids and related enzyme activities, and promote the smooth development of the experiment.
What are the physicochemical properties of 4- (2 - Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt is a commonly used reagent for biochemical research. Its physical and chemical properties are as follows:
In terms of solubility, this substance is mostly white crystalline powder with stable properties and is easy to store and use.
In terms of solubility, it exhibits good solubility in water and can quickly and uniformly disperse to form a uniform solution. This property is particularly critical in many experiments that require solution configuration, which is conducive to precise control of the concentration of the reaction system.
When talking about the melting point, there is a specific value, which is an important reference for identifying this compound and controlling the experimental temperature. At the corresponding melting point temperature, the state of the substance changes from solid to liquid, which is relatively sensitive and of great significance for purity detection.
In terms of pH, as an important buffer, it has excellent buffering ability in a specific pH range. It can effectively maintain the stability of the pH value of the solution, free from a small amount of external acid and alkali interference, and can ensure the smooth progress of the reaction in simulated biological environments or pH-sensitive chemical reactions.
From the perspective of stability, it is usually quite stable under normal conditions. However, it is necessary to avoid contact with strong oxidants, strong acids, strong bases and other substances to prevent chemical reactions from occurring, causing deterioration and affecting the use effect.
In addition, its hygroscopicity also needs attention, and it should be stored in a dry environment, otherwise it is easy to absorb moisture in the air, change its physical state and concentration, and adversely affect the accuracy of the experiment.
4- (2 - Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt
4- (2-hydroxyethyl) piperazine-1-ethanesulfonic acid, sodium salt, hereinafter referred to as a certain sodium salt. The preservation method of this chemical agent is very important. Due to its special nature, it should be stored in a cool, dry and well-ventilated place.
A cool place can avoid high temperature to change its properties. Under high temperature, or trigger chemical reactions, damage its chemical structure and reduce its efficacy. If it is in a hot summer place, it is not properly stored in a cool place, or it may deteriorate.
A dry place prevents it from being damp. A sodium salt may dissolve or react hydrolytically in contact with water, affecting its quality. If stored in a humid environment, water vapor will adhere to the agent, and it will agglomerate and reduce activity for a long time.
Good ventilation is also key. It can disperse harmful gases that may be generated, and keep the environment fresh and avoid the influence of other pollutants.
Furthermore, it needs to be properly sealed when storing. To prevent excessive contact with air and oxidation reactions. In the laboratory, it is often stored in a sealed container, which is sealed immediately after use to prevent air intrusion.
Packaging materials also need to be considered. Materials with stable chemical properties and no reaction with a certain sodium salt should be selected. Glass or specific plastic containers are commonly used because they can keep the agent stable. All of these are the key to properly preserving 4- (2-hydroxyethyl) piperazine-1-ethanesulfonic acid, sodium salt, and following them can ensure its quality and effectiveness.
What are the precautions for 4- (2 - Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt in the experiment
4 - (2-hydroxyethyl) piperazine-1-ethane sulfonate sodium salt, namely HEPES sodium salt, has a number of urgent precautions and needs to be treated with caution during the experiment.
The first to bear the brunt is its dissolution. Although this salt has a certain water solubility, when it dissolves, it is still appropriate to add it to the solvent under moderate stirring to ensure that it is evenly dispersed and completely dissolved. If it is too hasty, it may cause the local concentration to be too high and the dissolution is not complete, which will affect the follow-up experiment. And the water temperature also needs to be paid attention to, often at room temperature, overheating or overcooling may interfere with its dissolution characteristics.
Furthermore, the pH adjustment of the solution is crucial. HEPES sodium salt is often used as a buffer, and its buffer range is about pH6.8-8.2. When configuring the buffer solution in the experiment, it is necessary to use a precision pH measuring instrument to finely adjust it to the pH value required for the experiment. Because its buffering capacity is excellent in a specific pH range, deviating from this range, the buffering effect will be sharply reduced, or the pH of the experimental system will fluctuate, affecting the accuracy of the experimental results.
Repeat, storage should not be underestimated. This salt should be stored in a dry, cool and dark place to prevent moisture, heat and light from deterioration. If exposed to improper environments for a long time, its chemical properties or changes, such as oxidation and other reactions, will greatly reduce the experimental effect. After taking it, be sure to seal it in time to ensure its quality.
In addition, during use, it is necessary to consider its compatibility with other reagents. In different experimental systems, there are many reagents that are compatible with them, and some reagents may chemically react with them to change their chemical structure or buffering properties. Therefore, before launching a new experiment, it is advisable to consult relevant materials or pre-do a small test to confirm its compatibility before formal experiments can be carried out to avoid falling short.
What distinguishes 4- (2 - Hydroxyethyl) Piperazine-1-Ethanesulfonic Acid Sodium Salt from other similar reagents
4- (2-hydroxyethyl) piperazine-1-ethanesulfonate sodium salt, which is different from other similar reagents, related to its properties, uses and characteristics.
This reagent has a unique chemical structure and is in the state of a weakly acidic buffer, which can maintain the pH stability of the solution in a specific pH range. Its buffer range is about 6.8-8.2, and it is often used in biochemistry, cell culture and other fields. It is very effective in simulating the environment in vivo and ensuring the activity and stability of biomolecules.
Compared with other buffer reagents, the buffering ability of 4- (2-hydroxyethyl) piperazine-1-ethane sulfonate sodium salt accurately adapts to the needs of many biological experiments, slightly interferes with the biological system, and does not affect the normal function and reaction process of biomolecules. And its solubility is good, and it can be quickly and evenly dispersed in aqueous solution, laying the foundation for the smooth development of the experiment.
And some similar reagents, or the buffer range is different from it, such as Tris-HCl buffer range of 7.1-9.1, which is more suitable for alkaline environments; or due to chemical structure differences, it has different effects when interacting with biomolecules, such as some buffers may bind to specific proteins and change their conformation and activity. Another example is that some reagents have poor solubility, which easily causes the solution to be cloudy or precipitated, interfering with the experimental observation and analysis of results. 4 - (2-hydroxyethyl) piperazine-1-ethane sulfonate sodium salt has no such danger.
Therefore, when the experimenter chooses the reagent, he needs to weigh the length of 4 - (2-hydroxyethyl) piperazine-1-ethane sulfonate sodium salt and other similar reagents according to the specific requirements of the experiment and system characteristics, etc., in order to achieve the best experimental effect.