4-(2-Hydroxyethyl) Piperazine-1-Propanesulfonic Acid

Lingxian Chemical

Specifications

HS Code	851451
Name	4-(2-Hydroxyethyl) Piperazine-1-Propanesulfonic Acid
Abbreviation	HEPPS
Chemical Formula	C8H18N2O4S
Molar Mass	238.305 g/mol
Appearance	White to off - white crystalline powder
Ph Range	7.2 - 8.8
Pka	7.8 (at 25°C)
Solubility	Soluble in water
Stability	Stable under normal conditions
Biological Compatibility	Good biological compatibility
Buffering Capacity	Effective buffering capacity within its pH range

Packing & Storage

Packing	100g of 4-(2 - Hydroxyethyl) Piperazine - 1 - Propanesulfonic Acid in resealable plastic bag.
Storage	4-(2-Hydroxyethyl) Piperazine-1-Propanesulfonic Acid should be stored in a cool, dry place, away from direct sunlight and sources of heat. Keep it in a tightly sealed container to prevent moisture absorption. As it's a chemical, avoid storing near reactive substances. Ideal storage conditions help maintain its stability and integrity for reliable use in laboratory applications.
Shipping	4-(2-Hydroxyethyl) Piperazine - 1 - Propanesulfonic Acid is shipped in well - sealed, corrosion - resistant containers. Ensured compliance with chemical transport safety regulations, proper labeling to denote its nature during transit.

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4-(2-Hydroxyethyl) Piperazine-1-Propanesulfonic Acid

General Information

Historical Development

4- (2-hydroxyethyl) piperazine-1 -propanesulfonic acid is widely used in the field of chemical industry. Tracing its historical evolution, early years, when many wise men were exploring the chemical industry, they needed more and more excellent reagents. So some researchers worked hard, and after repeated experiments and adjustments, they finally obtained this product. At the beginning, the preparation method was complicated and the production effect was not abundant. However, the years have passed, and the researchers have made unremitting efforts to improve the process, so that the yield has gradually increased and the quality is better. Therefore, it has been widely used in biochemical research, pharmaceutical preparation and many other aspects, adding a brilliant pen to the process of chemical development.

Product Overview

Today there is a product called 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid. This is a wonderful chemical product and has a wide range of uses in biochemical research. Its mild nature can stabilize the acid and base of the solution and create a suitable environment for many reactions.
Looking at its shape, it is often a white crystalline powder, which is easy to store and use. When preparing, it requires fine operation. According to scientific methods, the temperature, time and material ratio of the reaction can be controlled to obtain high-purity products.
In the field of biochemical experiments, it is like a good friend. Many studies of proteins and enzymes rely on it to maintain a stable environment and maintain the activity of substances, so that the experimental results are accurate and reliable. It is an indispensable and important reagent for biochemical research, which benefits scientific research.

Physical & Chemical Properties

The physicochemical properties of 4 - (2-hydroxyethyl) piperazine-1-propanesulfonic acid are particularly important. Looking at its properties, it is often in the state of white crystalline powder and is relatively stable in air. Its solubility is quite good and it is easily soluble in water, which makes it easily dispersed in many solution systems. When it comes to the melting point, it is roughly within a specific range, which is one of the keys to its physical characterization. And its pH buffering performance is excellent, which can effectively maintain the stability of the pH of the system within a specific pH range. This chemical property makes it widely used in biological, chemical experiments and other fields, which can help create a suitable reaction environment and ensure the smooth and orderly progress of various reactions and experiments.

Technical Specifications & Labeling

There are 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid products today, and its technical specifications and identification (commodity parameters) are the key. The technical specifications of this product must be clear that its ingredients are pure, the content must be accurate, and the amount of impurities should be strictly controlled in trace amounts. Its properties should be in a specific state, or powder, or crystalline, with pure color. On the label, the product parameters must be detailed, such as molecular weight, melting point, boiling point and other data, which must be clearly marked so that the user can see at a glance, in view of its quality, to ensure that it can be accurately adapted to various uses, and to play its due effect. Do not make the specifications unclear, the logo is confused, and the user may be at risk of misjudgment.

Preparation Method

The method of preparing 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid is as follows:
Raw materials and production process, select high-quality raw materials, 2-hydroxyethyl piperazine, 1,3-propanesulfonactone, etc., according to the precise ratio, dissolve it with a suitable solvent. Reaction steps, control the temperature to a suitable degree, or slowly heat up to a certain value, stabilize and respond to it, continue to adjust the temperature to promote its completion, during which pay attention to the reaction state, such as color change, gas output, etc. Catalytic mechanism, add an appropriate catalyst, speed its response, yield, and maintain the activity and quantity of the catalyst. In this way, after multiple control and refining steps, this 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid can be obtained for various required domains.

Chemical Reactions & Modifications

The compounds of Fu 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid are crucial for chemical reaction and modification. Its reaction, or the interaction between acid and base, or the rearrangement of molecules, needs to be precisely controlled. When modifying, new groups can be introduced to adjust its physicochemical properties.
To make its reaction smooth and modified properly, the mechanism of the reaction, such as temperature, solvent, catalyst, etc., must be studied. All factors have a great influence on its reaction and modification. Only by accurately observing and making good use of it can we obtain the ideal product, paving the way for chemical research and industrial production, increasing its efficiency and expanding its application field.

Synonyms & Product Names

4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, this substance is quite useful in biochemical research. Its nicknames are various, such as HEPPS, which are all synonymous names. Sold in the market, it is often commensurate with such synonymous names.
Although the study of Guanfu in ancient times has not been as refined as it is today, it has not been lax to explore the properties and uses of substances. Today's 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, if in ancient times, scholars must consider its characteristics and functions in detail. Although it does not have today's name, it may already exist in various explorations.
Nowadays, as a biochemical reagent, it is indispensable in many experiments and research scenarios. Due to the complexity of its synonymous name and trade name, it can also be seen that the academic and industry attach great importance to it. They all serve the purpose of accurate appellation and convenient use. They are expected to travel smoothly on the road of scientific research and achieve fruitful results.

Safety & Operational Standards

There are currently 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid products. Safety and operating standards are of paramount importance and should be described in detail.
When operating this product, it is necessary to ensure that the environment is well ventilated. Operators should wear suitable protective equipment, such as protective clothing, gloves, and wear goggles to prevent the product from touching the skin and eyes and causing harm.
When storing, there are also regulations. It should be placed in a cool, dry and well ventilated place, away from fire and heat sources. It should be kept separate from oxidants, acids, alkalis, etc., and should not be mixed with storage to prevent dangerous chemical reactions.
If you accidentally come into contact with this product, the emergency measures are as follows. If it touches the skin, immediately rinse with a large amount of flowing water, and then seek medical treatment; if it splashes into the eye, quickly rinse with a large amount of water or normal saline, and also need to seek medical attention as soon as possible; if you inhale, you should immediately move to a place with fresh air to keep the respiratory tract unobstructed. If breathing difficulties, you need to give oxygen. If breathing stops, you should immediately perform artificial respiration and seek medical attention. If you take it by mistake, do not induce vomiting, and seek medical treatment as soon as possible.
Operating this product must follow the above safety and operating norms to ensure that it is safe and must not be negligent, so as not to cause harm.

Application Area

4- (2 -hydroxyethyl) piperazine-1 -propanesulfonic acid, this compound has a wide range of application fields. In the field of biochemical research, it can be used as a buffer to stabilize the acid and base of the system and maintain the activity and structure of biomolecules. For example, when cells are cultured, create a suitable acid-base environment to help cells grow and metabolize normally. In medical testing, it is also commonly used to stabilize the detection environment and improve the accuracy of test results. In the study of proteins and enzymes, it provides stable acid-base conditions for them to explore their characteristics and functions. In the process of drug development, it also ensures the stability of acid and base in the reaction system, which is of great significance for drug synthesis and property research. Overall, it is crucial in many fields such as biochemistry and medicine, and is an indispensable material for scientific research and application.

Research & Development

Today, there is a substance called 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, which is an important research object for our chemical researchers. This substance has unique properties, a wide range of uses, and is related to the progress of many fields.
We have dedicated ourselves to studying its structural properties to understand its chemical principles. We have also investigated its reaction laws, hoping to expand its application. After long-term research, the synthesis method has been improved to improve its yield and purity, laying the foundation for its large-scale application.
However, the road of research is not smooth, and we have also encountered problems, such as the precise control of reaction conditions and the effective removal of impurities. We will continue to explore, try new paths, and hope to overcome difficulties. Over time, this substance will surely thrive in scientific research, industry, and many other aspects, promoting the progress and development of the industry.

Toxicity Research

Fu Jin wants to talk about the toxicity study of 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid. This chemical has attracted much attention in current research.
Examine its properties in detail to explore its effects in various environments and organisms. Observe its effects on biological cells to see if it damages the cell structure or disrupts the order of its metabolism. Test in animals, and review the changes in organs and physiological functions after ingestion.
Although there are more and more studies today, many details are still unclear. The strength of toxicity varies according to dose and duration of exposure. We should study the mechanism of its toxicity in a rigorous manner, explore the breadth and depth of its impact, and hope to clarify its advantages and disadvantages in ecology and human body, so as to provide evidence for future use or prevention of its harm.

Future Prospects

Guanfu 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid is very important in today's biochemical research. Although it has been used now, it does not stop there.
Looking forward to the future, its methods for biochemical analysis should be more refined. Or it can meet the needs of diverse research with more refined purity and better characteristics. And in the field of biomedicine, it is also expected to emerge, helping the research of new drugs and the treatment of diseases.
Our generation of biochemical researchers, with an enterprising heart, should explore the wonders of this substance. Hoping for the future, to be able to expand its use and develop its capabilities, to open up a new scene for the benefit of biochemistry and people's livelihood, is also for our unfulfilled wish.

Frequently Asked Questions

What are the main application fields of 4- (2 - Hydroxyethyl) Piperazine-1-Propanesulfonic Acid

4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid is important in the fields of biochemical experiments and pharmaceutical and chemical industries.
In biochemical experiments, one of them is used as a buffer. Biochemical reactions in organisms can be carried out smoothly under a specific pH environment. This substance can effectively maintain the stability of the pH of the reaction system through its own acid-base balance mechanism. The activity of biological macromolecules such as proteins and enzymes is highly susceptible to pH changes. The stable acid-base environment created by 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid can protect the structure and function of biological macromolecules from pH interference, making the experimental results more accurate and reliable.
In the field of pharmaceutical and chemical industry, its use is also wide. In the process of drug development, the stability and solubility of drugs are crucial. This substance can act as a buffer component for pharmaceutical preparations, improve the stability of drugs in different physiological environments, and ensure the efficacy of drugs. And in some external preparations, such as cosmetics, ointments, etc., the addition of this substance can adjust the pH of the product, make it more suitable for the acid-base environment of human skin, reduce the irritation to the skin, and enhance the safety and applicability of the product.
Therefore, 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid plays an indispensable role in biochemistry and pharmaceutical chemistry, and contributes greatly to the development of related fields.

What are the chemical properties of 4- (2 - Hydroxyethyl) Piperazine-1-Propanesulfonic Acid

4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, which is mild in nature and mostly exists in the buffer system of biochemical experiments.
This substance is a white crystalline powder with high purity and good solubility. It can be quickly dissolved in water and common organic solvents, making it easy to prepare the required concentration solution in various experimental environments. Its pH buffer range is about 6.8-8.2, just like a loyal guard. In this range, it can tenaciously maintain the pH stability of the system regardless of how the external acid and alkali interfere. Many biochemical reactions are extremely sensitive to pH fluctuations, and the slightest carelessness will deviate from the right track. The key role of this substance is to ensure the smooth progress of the reaction.
Furthermore, its chemical properties are stable, and it does not easily react with other substances in the system under conventional experimental conditions. It is like a calm lake water, which does not easily ripple, so it will not interfere with the biochemical reaction process studied, which lays a solid foundation for the accuracy and reliability of the experiment. In addition, it is almost non-toxic and non-interfering to bioactive substances, just like a gentle hand, which protects the natural structure and function of biomolecules without affecting their activity, providing a safe and suitable environment for biological experiments. Many experiments such as cell culture, enzyme activity determination, and protein crystallization rely on it to ensure the smooth development of experiments. It is an indispensable and important reagent in the field of biochemistry.

What is the concentration range of 4- (2 - Hydroxyethyl) Piperazine-1-Propanesulfonic Acid used in biological experiments?

4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, often abbreviated as HEPPS, is a commonly used buffer in biochemical experiments. The concentration range of HEPPS used in biochemical experiments varies depending on the specific needs of the experiment.
In most conventional biochemical experiments, the concentration of HEPPS used is about 10 mM to 100 mM. If the experiment is a protein-related study, if you want to maintain a specific pH environment to ensure protein stability and activity, the concentration of HEPPS is usually set at 20 mM to 50 mM. Because of this concentration range, the pH value of the solution can be effectively buffered, so that the protein can be in a suitable environment to prevent its structure and function from being damaged.
In the enzyme activity determination experiment, in order to simulate the physiological environment in the organism and allow the enzyme to exhibit the best activity, the concentration of HEPPS may be adjusted to about 50 mM. Due to the different pH sensitivity of different enzymes to the environment, the suitable buffer concentration is also different, and the concentration of 50 mM may meet the needs of most enzyme activity determination.
Another cell culture-related experiment, in order to maintain a suitable pH environment for cell growth, the concentration of HEPPS is usually controlled at 10 mM to 30 mM. Cells are quite sensitive to environmental changes. This concentration range can not only ensure the buffering effect, but also will not have adverse effects on cells, ensuring normal cell growth and metabolism.
It should be noted that in actual experiments, the concentration of HEPPS should be carefully optimized according to the specific experimental purpose, sample characteristics and other experimental conditions to achieve the best experimental effect.

4- (2 - Hydroxyethyl) Piperazine-1-Propanesulfonic Acid Compatibility Issues with Other Chemicals

4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, often used as a biological buffer, is extremely important in biochemical research. When it comes to whether this substance is incompatible with other chemical substances, it is necessary to carefully consider.
The properties of chemistry and the reactions between substances are related to their structure and functional groups. 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid has a specific molecular structure and contains piperazine ring, hydroxyethyl group and propanesulfonic acid group. Its piperazine ring is alkaline to a certain extent, hydroxyethyl group is hydrophilic, propanesulfonic acid group is acidic and ionic.
When encountering a strong oxidant, because it contains atoms with certain reducing properties such as nitrogen and oxygen, or an oxidation reaction, the structure is damaged, which is one end of the incompatibility. And if it is a strong acid and a strong base, because of its own acid-base buffering properties, although it can resist a certain degree of pH change, it is also incompatible when the strong acid and a strong base are too strong, or break its buffer system and cause a chemical reaction.
Re-discussion of metal ions, some high-valent metal ions, such as iron ions, copper ions, etc., may coordinate with the nitrogen and oxygen atoms of the substance to change the properties and structure of the compound, which is also an incompatible situation that cannot be ignored.
In organic reagents, those with active functional groups, such as acyl chloride, acid anhydride, etc., or react with the hydroxyl and amino groups of 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, causing incompatibility.
However, many substances, if their chemical properties are stable, are inactive with the functional groups of 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid. In order to judge whether it is compatible with other chemical substances, the chemical properties and reactivity of each substance must be investigated in detail.

What are the storage conditions for 4- (2 - Hydroxyethyl) Piperazine-1-Propanesulfonic Acid?

4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, often referred to as HEPPS, is a commonly used buffer for biochemical experiments. Its storage conditions are quite critical, as follows:
First, it needs to be placed in a cool place. Direct sunlight or too high temperature can cause its chemical properties to change. Due to the increase in temperature, or the intensification of molecular movement, chemical reactions are more likely to occur and cause it to deteriorate. A cool place can effectively slow down such changes and maintain its stability.
Second, it should be stored in a dry place. HEPPS has a certain water absorption. If the ambient humidity is high, it is easy to absorb water or cause deliquescence, which affects the purity and performance. If in the rainy season in the south, the air humidity is extremely high, and it is necessary to pay more attention to the dryness of the storage environment.
Third, it must be sealed and stored. Placed open, it is not only easy to absorb water, but also may react with gases such as oxygen and carbon dioxide in the air. For example, carbon dioxide can interact with certain basic groups, changing the chemical structure of HEPPS, which in turn affects its buffering performance.
Fourth, keep away from fire sources and oxidants. Although HEPPS is not flammable and explosive, under certain special conditions, it may react violently with oxidants, causing danger. Therefore, when storing, keep a safe distance from fire sources and oxidants.
In conclusion, 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid should be stored in a cool, dry, sealed place, and away from ignition and oxidants, so as to ensure its quality and performance, and play its due role in the experiment.