What is the chemical structure of 4- ({4- [Acetyl (Methyl) Amino] Phenyl} Amino) -1-Amino-9,10-Dioxo-9, 10-Dihydroanthracene-2-Sulfonic Acid?
This is an extremely complex organic compound named 4- {4- [acetyl (methyl) amino] phenylamino} -1 -amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid. To clarify its chemical structure, it is necessary to follow the principles of organic chemistry.
The core structure of this compound is anthracycline, anthracycline, which is a polycyclic aromatic hydrocarbon with three fused phenyl rings. At the 9th and 10th positions of anthracycline, each connected with a carbonyl group, it forms the structure of 9,10-dioxo-9,10-dihydroanthracene, which affects the electron cloud distribution and chemical activity of the compound.
At the second position of anthracycline, it is connected to a sulfonic acid group (-SO-H). The sulfonic acid group has strong hydrophilicity, which increases the solubility of the compound in water. At the first position, the amino group is a basic group, which can participate in many chemical reactions, such as salt formation reactions.
Furthermore, the group connected at the fourth position is more complex, which is connected by a phenyl ring and an acetyl (methyl) amino group, and then is connected to the nitrogen atom at the fourth position of the anthracycline. Among them, in the acetyl (methyl) amino group, the acetyl group (CH 🥰 CO -) and the methyl group (CH 🥰 -) are connected to the nitrogen atom, and this structure affects the electron cloud density of the benzene ring, which in turn affects the reactivity and physical properties of the whole compound.
In this way, this compound is composed of a combination of various functional groups and a specific carbon skeleton, and each part affects each other, resulting in its unique chemical and physical properties.
What are the main uses of 4- ({4- [Acetyl (Methyl) Amino] Phenyl} Amino) -1-Amino-9,10-Dioxo-9, 10-Dihydroanthracene-2-Sulfonic Acid?
4 - {4 - [acetyl (methyl) amino] phenyl} amino - 1 - amino - 9,10 - dioxo - 9,10 - dihydroanthracene - 2 - sulfonic acid, this substance is widely used. In the field of printing and dyeing, it is often used as the backbone of dyes. Because of its unique structure, it can give fabrics bright color, and has excellent light resistance and washable fastness. After the fabric is colored, the color is enduring, and it is very popular in various textile dyeing processes.
In the path of scientific research and exploration, this compound is also of important value. Scientists often use it as a key raw material to create new functional materials through chemical modification, structural modification and other means. For example, building photochromic materials, which can change colors sensitively under light stimulation, has broad application prospects in cutting-edge fields such as optical sensors and information storage; or building fluorescent probes, which can achieve accurate detection and analysis of substances in organisms by virtue of their highly selective identification ability of specific substances, and help life science research to a deeper level.
Furthermore, in the field of pharmaceutical research and development, it can also be seen. Because of its structure, it is similar to some bioactive molecules, which may provide inspiration for drug molecular design. Through in-depth analysis and optimization of its structure, it is expected to develop drugs with novel mechanisms of action, providing a new way to overcome difficult diseases.
What are the physical properties of 4- ({4- [Acetyl (Methyl) Amino] Phenyl} Amino) -1-Amino-9,10-Dioxo-9, 10-Dihydroanthracene-2-Sulfonic Acid?
4 - {4 - [acetyl (methyl) amino] phenyl} amino - 1 - amino - 9,10 - dioxo - 9,10 - dihydroanthracene - 2 - sulfonic acid, this is an organic compound. Its physical properties are as follows:
In terms of normal temperature and pressure, it is mostly solid or crystalline powder. Due to the characteristics of molecular structure, it has a certain orderly arrangement, resulting in a specific crystal shape.
In terms of color state, it is usually white to light yellow. This color characteristic is due to the absorption and reflection characteristics of the molecule to visible light. The optical band involved in the electron transition energy level in the molecular structure does not cover the full spectrum of visible light, so it presents this color system.
In terms of solubility, it has a certain solubility in water. The molecular structure contains sulfonic acid groups, which are hydrophilic groups that can form hydrogen bonds with water molecules to promote dissolution. However, the hydrophobicity of the rest of the molecule limits its solubility, so the solubility is not very high. In organic solvents such as ethanol and acetone, the solubility may vary due to the different forces between the solvent and the solute molecule. Polar organic solvents interact strongly with molecular partial groups or increase the solubility slightly. The melting point of
is also an important physical property. It has been experimentally determined that its melting point is in a specific temperature range. This is because when heated, the molecules gain energy and the vibration intensifies. When a certain temperature is reached, the lattice structure is destroyed and the solid state is converted to a liquid state. The melting point value is closely related to the intermolecular forces. The stronger the intermolecular hydrogen bonds, van der Waals forces, etc., the higher the energy required to maintain the lattice structure and the higher the melting point. The melting point of this compound reflects the strength of the intermolecular interactions.
What is the synthesis method of 4- ({4- [Acetyl (Methyl) Amino] Phenyl} Amino) -1-Amino-9,10-Dioxo-9, 10-Dihydroanthracene-2-Sulfonic Acid?
To prepare 4- {4- [acetyl (methyl) amino] phenyl} amino-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid, the method is as follows:
First take an appropriate amount of anthraquinone-2-sulfonic acid, place it in a clean kettle, use water as a solvent, slowly heat it to an appropriate temperature, so that it is fully dissolved. Another amount of 4- (methylamino) acetaniline, after fining, slowly add it to the above kettle, and add an appropriate amount of catalyst at the same time, stir evenly, keep the temperature constant, and carry out the condensation reaction. During the reaction, it is necessary to pay close attention to the changes in the kettle, and adjust the temperature and stirring rate in a timely manner.
Wait for the reaction to be completed asymptotically, reduce the temperature in the kettle, and allow the reaction products to slowly precipitate. After that, the resulting mixture is filtered and the filter cake is collected. Then the filter cake is washed with an appropriate solvent to remove impurities. After washing, the filter cake is placed in an oven and dried at controlled temperature to obtain a crude product.
To obtain a high-purity product, the crude product needs to be refined. The crude product is recrystallized with a suitable organic solvent, heated and dissolved, and filtered while hot to remove insoluble matter. The filtrate is allowed to stand and cool. After the crystallization is complete, filter again to collect crystals. The crystals were dried at low temperature to obtain pure 4- {4- [acetyl (methyl) amino] phenyl} amino-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid. During the whole process, it is necessary to pay attention to the operation specifications to ensure the purity of the drug and the accuracy of the reaction conditions to obtain high-quality products.
4- ({4- [Acetyl (Methyl) Amino] Phenyl} Amino) -1-Amino-9,10-Dioxo-9, 10-Dihydroanthracene-2-Sulfonic Acid What are the precautions during use?
4 - {4 - [acetyl (methyl) amino] phenyl} amino - 1 - amino - 9,10 - dioxo - 9,10 - dihydroanthracene - 2 - sulfonic acid This chemical substance has many points to be paid attention to during use.
First, because of its specific chemical structure and properties, it may be potentially harmful to the human body. Be sure to take good protection when operating, wear suitable protective clothing, gloves and goggles to prevent the substance from coming into contact with the skin and eyes. If it comes into contact, rinse with plenty of water immediately and seek medical assistance according to the specific situation.
Second, the chemical substance may have certain toxicity and irritation, and the use site should ensure good ventilation to prevent inhalation of its volatiles. If used in a relatively closed space, effective ventilation equipment should be equipped to avoid the accumulation of harmful substances.
Third, when storing, it should be properly placed according to its chemical characteristics. Keep away from fire and heat sources to prevent fires or chemical reactions caused by temperature changes. At the same time, it should be stored separately from other chemical substances to avoid mutual reactions, resulting in changes in properties or dangerous substances.
Fourth, strictly follow the established operating procedures and dosage requirements when using. Do not change the method and dosage at will to prevent affecting the effect or causing safety problems. Seal and store it in time after use to prevent it from deteriorating in contact with air, moisture, etc.
Finally, the waste generated during use cannot be discarded at will, and should be properly disposed of in accordance with relevant environmental regulations to avoid pollution to the environment. In short, when using this chemical, safety and standardized operation are of paramount importance and must not be taken lightly.