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What is the chemical structure of 4,5,6,7-tetrahydrothieno [3,2-C] pyridine-2 (3H) -one 4-methylbenzenesulfonate
The chemical structure of 4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2 (3H) -ketone 4-methylbenzenesulfonate is described below.
The basic structure of this compound is the fused heterocyclic system of pyrrolido-pyridine. In the pyrrolido-pyridine part, the pyrrole ring is fused with the pyridine ring in a specific [3,2-C] manner. In the second position of the fused system (and labeled 2 (3H), meaning that this position is in the 3-hydrogen state), a carbonyl group (ketyl group) exists, which has a significant effect on the reactivity and physical properties of the molecule.
and there is a methyl benzenesulfonate group connected at the 4th position. Among them, the methyl benzenesulfonate part is composed of a benzene ring, a sulfonate group (-OSO 2O -) and a methyl group. The benzene ring endows the molecule with certain aromaticity, enhances its stability and hydrophobicity; the sulfonate group is a good leaving group, which plays a key role in many organic reactions, which can make the compound prone to nucleophilic substitution and other reactions; the methyl group is connected to the benzene ring, which moderately changes the electron cloud distribution and spatial hindrance of the molecule.
In summary, the chemical structure of 4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2 (3H) -ketone 4-methylbenzenesulfonate is composed of a unique fused heterocycle with specific substituents. The interaction of each part determines the chemical properties and reactivity of the compound.
What are the main uses of 4,5,6,7-tetrahydrothieno [3,2-C] pyridine-2 (3H) -one 4-methylbenzene sulfonate
4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2 (3H) -ketone 4-methylbenzenesulfonate, which has a wide range of uses.
In the field of medicinal chemistry, it is often involved in the synthesis of many drugs as a key intermediate. Take some neurological diseases as an example, with its unique chemical structure, it can precisely bind to specific receptors, which in turn play a role in regulating neurotransmitter transmission and other functions, helping to relieve diseases.
In the field of organic synthesis chemistry, due to the active groups contained in the structure, it can participate in a variety of reactions, such as nucleophilic substitution, cyclization, etc., in order to build a more complex organic molecular framework, help organic synthesis chemists to construct novel compound structures, and provide a key material basis for new drug development and new material exploration.
At the same time, in the field of materials science, some of its derivatives may be able to impart special electrical and optical properties to materials after specific modifications, so as to be applied to the preparation of materials such as organic Light Emitting Diode (OLED) and sensors, and promote technological innovation and development in related fields.
What is the synthesis method of 4,5,6,7-tetrahydrothieno [3,2-C] pyridine-2 (3H) -one 4-methylbenzene sulfonate
To prepare 4-methylbenzo [3,2-c] misoline-2 (3H) -one, the following ancient method can be used:
First take the appropriate raw materials, use benzo [3,2-c] misoline as the base, and its 4,5,6,7-tetrahydrogen structure is the initial structure. To find the appropriate reaction conditions, the classic method of organic synthesis is often used, and the target can be obtained through several steps of transformation.
Initially, the parent body of benzo [3,2-c] misoline-2 (3H) -one can be modified. If a suitable alkylation reagent is selected, the parent is placed in a specific reaction environment, or in an organic solvent, a suitable catalyst is added, and the temperature is raised to a certain extent, so that the alkylation reaction can be carried out. The methyl group is introduced to the 4-position, and 4-methylbenzo [3,2-c] aconoline-2 (3H) -one is obtained.
During this period, the choice of organic solvent needs to consider its solubility to the reactants and products, and does not have side reactions with the reaction system. The choice of catalyst is also key, which can accelerate the reaction process and improve the selectivity of the reaction. The degree of heating needs to be precisely controlled. If it is too high or causes a cluster of side reactions, if it is too low, the reaction rate will be slow, which is not conducive to the formation of the product.
After the reaction is completed, the impurities are removed by separation and purification, or by means of column chromatography, recrystallization, etc., to obtain pure 4-methylbenzo [3,2 - c] aconoline-2 (3H) -one. During column chromatography, the appropriate fixed phase and mobile phase are selected to separate according to the polarity of the product and the impurity. Recrystallization selects a solvent whose solubility of the product changes significantly with temperature. After heating, it is dissolved and cooled to crystallize to obtain a high-purity product.
What are the purity requirements for 4,5,6,7-tetrahydrothieno [3,2-C] pyridine-2 (3H) -one 4-methylbenzene sulfonate?
4% 2C5% 2C6% 2C7-tetrahydrofuro [3,2-C] pyridine-2 (3H) -ketone-4-methylbenzenesulfonate is an organic compound. To obtain its purity, this is related to the key indicators in the fields of fine chemistry and drug synthesis.
In the context of "Tiangong Kaiwu", although there was no modern method for accurate determination of purity at that time, it can be somewhat understood by analogy with the pursuit of material purity by traditional processes. In the past, refined materials were often washed, refined, calcined and other processes to remove impurities and seek their purity.
To test the purity of this substance today, modern chemistry has various wonderful methods. If high performance liquid chromatography (HPLC) is used, the difference in the partition coefficient of different components in the stationary phase and the mobile phase is used to achieve separation and quantitative analysis. After the sample is injected into the liquid chromatograph and separated by the chromatographic column, each component peaks in sequence, and the area of the peak is compared with the standard product, which can accurately determine its purity. Gas chromatography (GC) can also be used for the analysis of volatile components. If the compound is suitable for volatility, it can be separated in the gas chromatographic column after gasification to measure the purity.
In addition, mass spectrometry (MS) can also be used to provide information on the molecular weight and structural fragment of the compound, which can be compared with the standard mass spectrogram to assist in the determination of purity and impurity composition. There are also melting point determination methods. The melting point of pure compounds is fixed. If impurities are contained, the melting point decreases and the melting range widens. By accurately measuring the melting point, the purity can be preliminarily evaluated. However, in order to obtain accurate results, it is advisable to combine multiple methods. In summary, according to the delicacy of modern chemical analysis methods, the exact value of the purity of 4-methylbenzenesulfonate can be obtained.
What is the market price of 4,5,6,7-tetrahydrothieno [3,2-C] pyridine-2 (3H) -one 4-methylbenzene sulfonate?
I look at what you are asking about the market price of 4-methyl umbrella ketone-2- (3H) -ketone 4,5,6,7-tetrahydrobenzo [3,2-C] furan-2- (3H) -ketone. However, this compound is not familiar to me, and its price varies due to many factors.
If its preparation requires exquisite craftsmanship, rare raw materials, and production is difficult, like climbing a dangerous peak, its price will be high. If refining rare medicinal pills requires rare and exotic grass, and it can be achieved through multiple complicated processes, the price is naturally high.
And if there is little demand for this thing in the world, it is like a mountain hermit, and few people want it, then although it is difficult to prepare, its price may be limited. Cover the market supply and demand, and determine its price.
Furthermore, there are many merchants in the market, and the competition is fierce, and the price may fluctuate. Just like a place where merchants gather, people compete for profits, and the price may vary.
However, it is difficult for me to determine the specific price in the market. To know the details, you can go to the pharmacy, pharmacy and other related trading places, consult the shopkeeper, pharmacist, or look for it in the commercial books and documents in the city, and you can get the exact price.