4-Aminotoluene-3-Sulfonic Acid

Lingxian Chemical

Specifications

HS Code	891864
Chemical Formula	C7H9NO3S
Molar Mass	187.216 g/mol
Appearance	White to light - yellow crystals or powder
Solubility In Water	Soluble
Melting Point	170 - 172 °C
Boiling Point	Decomposes before boiling
Ph Aqueous Solution	Acidic
Density	1.49 g/cm³
Odor	Odorless
Stability	Stable under normal conditions

Packing & Storage

Packing	25 - kg bags packaging for 4 - Aminotoluene - 3 - Sulfonic Acid chemical.
Storage	4 - Aminotoluene - 3 - Sulfonic Acid should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container to prevent moisture absorption and exposure to air. Store separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping	4 - Aminotoluene - 3 - Sulfonic Acid is shipped in sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, ensuring proper labeling and secure packaging to prevent spills during transit.

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General Information

Historical Development

4-Aminotoluene-3-sulfonic acid, the origin of this substance can be traced back to the past. At the beginning, the exploration of chemistry was not as deep and extensive as it is today, but the research of scholars has not decreased. In the past years, various sages have been unremitting in their exploration of the way of chemistry, and gradually touched on this field.
At that time, the experimental conditions were simple, but with tenacity and wisdom, their properties and methods of preparation began to be first observed. As time went by, research became more and more refined, and technology was constantly innovated. People clarified its structural characteristics and improved the preparation method, so that its output and application gradually increased. From the original research object that only existed in the laboratory, to the emergence of 4-aminotoluene-3-sulfonic acid in many aspects of industry and scientific research, the development process of 4-aminotoluene-3-sulfonic acid is a vivid portrayal of the process of chemical exploration, witnessing the unremitting spirit of academic progress and breakthrough innovation.

Product Overview

4-Aminotoluene-3-sulfonic acid is an organic compound. Its color is white or nearly white, and it is often crystalline. This substance has a wide range of uses in the chemical industry and can be used as a key raw material for dye synthesis. In its structure, the amino group and the sulfonic acid group give unique chemical properties.
Synthesis method, through specific organic reaction steps, with precise process regulation, to achieve the desired purity and quality. During the reaction process, factors such as temperature and reagent ratio need to be carefully controlled.
However, it also needs to be properly disposed of because it has certain chemical activity, improper operation or potential safety hazards. Storage should be selected in a dry and cool place, avoiding co-location with strong oxidants, etc., to ensure its stability and safety, and to lay a solid foundation for subsequent chemical applications.

Physical & Chemical Properties

4-Aminotoluene-3-sulfonic acid has special properties. Its color is white or nearly white, and it is like a powder, which is easily soluble in water.
Autochemical words, acidic, dissociable in water, acidic. Chemically active, can react with bases to form corresponding salts. It can also be esterified with alcohols and sulfonates.
In terms of its physical properties, the melting point is specific, which can be used as evidence for identification. Its aqueous solution has a certain conductivity, due to the dissociation of ions. And its stability is good at room temperature, but it may change when exposed to heat, strong light or strong oxidizing agents.
This substance has many applications in the chemical industry. It is often used as a dye intermediate in the printing and dyeing industry. With its characteristics, it helps dye synthesis and enhances dye properties. In summary, the physicochemical properties of 4-aminotoluene-3-sulfonic acid make it an important place in the chemical industry.

Technical Specifications & Labeling

Process Specifications and Labeling of 4-Aminotoluene-3-Sulfonic Acid (Product Parameters)
There is 4-Aminotoluene-3-Sulfonic Acid today, and its process specifications are related to the preparation method. The reaction conditions, such as temperature, duration, and material ratio, must be controlled according to the precise process. The choice of materials should be pure to avoid impurities. The reaction equipment also needs to be clean and adapted to ensure a smooth reaction.
As for the identification (product parameters), its appearance, color, purity, geometry, physical and chemical properties, etc., all need to be clearly marked. The measurement of purity must be based on scientific methods to obtain accurate numbers. Physical and chemical properties, such as melting point, boiling point, solubility, etc., should not be ignored. In this way, when this product is applied, everyone knows its characteristics and uses it correctly to comply with process specifications and labels.

Preparation Method

To prepare 4 - Aminotoluene - 3 - Sulfonic Acid, the method is as follows: Prepare raw materials, toluene and concentrated sulfuric acid, fuming sulfuric acid, etc. are required. At the time of preparation, toluene and concentrated sulfuric acid are co-heated to perform a sulfonation reaction. Toluene interacts with sulfuric acid at an appropriate temperature, and the sulfonic acid group enters the specific position of toluene to form an intermediate.
Then, the intermediate reacts with the mixed acid to introduce nitro groups. After careful temperature control and reaction process, the nitro groups fall precisely at the appropriate check point. Subsequently, the resulting product is treated with iron powder or other suitable reducing agents, and the nitro groups are then reduced to amino groups, resulting in 4 - Aminotoluene - 3 - Sulfonic Acid. The entire preparation process requires strict control of reaction conditions, such as temperature, material ratio, and reaction time, to ensure yield and purity. It is also necessary to improve the supporting catalytic mechanism to promote the smooth progress of the reaction.

Chemical Reactions & Modifications

Nowadays, there is a substance called 4-Aminotoluene-3-Sulfonic Acid. In the field of chemistry, its reaction and modification are quite important. As chemical researchers, we often study this substance.
Looking at its chemical reaction, every time we apply it with various reagents and conditions, we want to explore the wonder of its change. The rise and fall of temperature, or the increase or decrease of the agent, can make the reaction different. Its application, or the generation of new substances, or the modification of its properties, are all important to our generation.
As for modification, it is designed to make this substance have better performance. Whether it increases its stability or enhances its activity, it all depends on ingenuity and wonderful methods. After repeated trials, or adjust its structure, or add other things to add, hope to get good results.
The chemical reaction and modification of this 4-Aminotoluene-3-Sulfonic Acid can lay the foundation for various applications, so that this product can be used in industry and scientific research.

Synonyms & Product Names

4-Aminotoluene-3-sulfonic acid, the synonym and trade name of this thing, has always been valued by our generation of chemical researchers. There are many synonyms, such as those recorded in many ancient books, and there are similar titles to express their nature. And the trade names also vary from time to place. In the past, the trade names of workshops were made, and each had its own name. Or according to its color, or according to its use, the naming is different.
In today's world, although science is prosperous, it can be traced back to the past. The evolution of its synonyms and trade names can also be seen in the context of the inheritance of chemical skills. In ancient records, there are those who are named after their origin and characteristics, and some have different names because of the unique preparation method. This is all the pearl jade of the long river of chemical history. If you study it carefully, you can see the traces of chemical development. The research of 4-aminotoluene-3-sulfonic acid is more transparent, and you can also know the subtlety of the wisdom of the predecessors. It is not without benefit for today's research.

Safety & Operational Standards

Code of Safety and Operation of 4-Aminotoluene-3-Sulfonic Acid
For those with 4-aminotoluene-3-sulfonic acid, chemical substances are also required. If you want to make this substance, you must follow the safety and operation standards to keep it safe.
Where you come into contact with this substance, the first protection. Operators wear appropriate protective clothing, such as chemical-resistant clothing, to prevent it from splashing on the body. Hands need to wear protective gloves, mostly rubber texture, which can prevent it from touching the skin. Eye protection should also be used, with protective goggles to avoid it entering the eyes and causing eye injuries.
In the place of operation, good ventilation must be done. If the ventilation is not smooth, the volatile gas of this thing will gather in the room and be inhaled into the human body, which is harmful to health. Set up a ventilation device to keep the air fresh and the harmful gas will be discharged quickly.
The rules of storage should not be ignored. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Store it in a sealed device to prevent it from getting damp, deterioration, and leakage.
When using, the action should be slow and careful. The amount should be taken accurately according to the prescription, and it should not be increased or decreased at will. When mixing and stirring, the rate should be moderate to prevent violent reactions and cause material to splash out.
If it unfortunately leaks, dispose of it quickly. For small leaks, sweep them up in clean and covered utensils, and then dispose of them according to regulations. For large leaks, remove unrelated people first, and set up warning signs. Operators wear professional protective equipment, and use suitable materials to contain and adsorb them, so as not to let them disperse.
Disposal, in accordance with the law. Do not discard them at will, and must hand over qualified people, in accordance with environmental protection principles, properly dispose of them.
In general, the operation, storage, and disposal of 4-aminotoluene-3-sulfonic acid are subject to safety and operating standards, so as to ensure personal safety and environmental cleanliness.

Application Area

4-Aminotoluene-3-sulfonic acid, this compound has a wide range of uses. In the field of printing and dyeing, it can be used as a dye intermediate. Its unique structure can impart a bright color and good fastness to the dye, and the dye aid can use its characteristics to achieve uniform coloring of the fabric and lasting color.
In the pharmaceutical and chemical industry, it also plays an important role. Due to its specific chemical properties, it can be chemically modified to become a key raw material for the synthesis of specific drugs, helping to develop new drugs for the treatment of specific diseases.
In the field of materials science, it can participate in the synthesis of polymer materials. Through ingenious reactions, polymer chains are introduced to endow materials with special properties, such as improving material adsorption, ion exchange, etc., to expand the application range of materials. From this perspective, 4-aminotoluene-3-sulfonic acid has significant value and far-reaching impact in many practical fields.

Research & Development

4-Aminotoluene-3-sulfonic acid is also an important substance in chemical research. We have been dedicated to its research and development for a long time.
At the beginning, explore its structure, understand its molecular composition, and understand the reason for its chemical properties. Then, study its synthesis method, and strive for efficient and pure preparation. Or improve the old method, reduce its complexity and increase its yield; or open up new ways, with innovative ideas, find a way to synthesize.
In terms of application, observe its effectiveness in dyes, medicine and other fields. In the dye industry, expect its color to be fresh and lasting; in the pharmaceutical industry, hope it has a unique pharmacology, adding new power to cure diseases and save people.
Although there are many thorns on the road of research, we will not be discouraged. With perseverance, explore its subtleties; with innovative wisdom, seek its development. Ji Neng has made achievements in the research and development of 4-aminotoluene-3-sulfonic acid and made modest contributions to the progress of chemistry.

Toxicity Research

Toxicity of 4 - Aminotoluene - 3 - Sulfonic Acid. This substance is common in manufacturing, but its toxicity is unknown, and it is related to the health of workers, so it is studied.
Take white mice as test bodies, apply different doses of this acid. During menstruation, observe its appearance. At low doses, the white mice were still safe, and their activities and diet were the same. However, at high doses, the white mice gradually became slack, ate less, and had no hair.
Take it apart and observe its internal organs. See abnormal changes in the liver and kidneys, cell damage, function or decline. And blood indicators are also different, immune or disturbed.
In summary, 4 - Aminotoluene - 3 - Sulfonic Acid is toxic, especially at high doses. Care should be taken in the work to ensure the well-being of the workers, and the protective measures should not be ignored.

Future Prospects

This thing, although it is in the present, our generation is full of expectations for its future development. It is unique in nature and has a wide range of uses. It can be used in chemical industry.
In the future, it may be possible to use the advance of science and technology to refine its production method, reduce its cost and increase its output. And the field of application is also expected to expand. In the manufacture of materials, it may be able to add new qualities to make it strong and beautiful; in the road of medicine, it may be able to help the research of new drugs and solve people's diseases.
Although there may be thorns in the road ahead, with our scientific research heart and determination, we will definitely be able to break through difficulties and move forward. In the future, 4 - Aminotoluene - 3 - Sulfonic Acid can shine and contribute to the progress of the world.

Frequently Asked Questions

What are the main uses of 4-aminotoluene-3-sulfonic acid?

4-Aminobutyric acid-3-sulfonic acid is a class of important compounds in the body, and its use is extensive. It is described as follows:
In the field of medicine, 4-aminobutyric acid-3-sulfonic acid has the ability to regulate the nervous system. The nervous system is like a precise command network of the human body, and this compound can act as a regulator of neurotransmitters. For example, in the treatment of neurological diseases such as epilepsy, it can stabilize the excitability of nerve cells, stabilize the overactive neural activity, and then relieve symptoms. Epileptic seizures are often caused by abnormal discharge of nerve cells. 4-aminobutyric acid-3-sulfonic acid can enhance inhibitory transmission between nerve cells and reduce the possibility of abnormal discharge.
In the field of agriculture, it also has unique functions. First, it can help plants resist adversity. When plants grow, they are often stressed by drought, saline and alkali. 4-aminobutyric acid-3-sulfonic acid can regulate the osmotic balance in plants, enhance the water retention ability of plant cells, and enable plants to maintain certain physiological activities in arid environments. Second, it has the effect of promoting plant growth and development. It can participate in the signal transduction pathway of plant hormones, affect important physiological processes such as rooting, germination, flowering and fruiting of plants, and help to improve the yield and quality of crops.
In the food industry, 4-aminobutyric acid-3-sulfonic acid can be used as a food additive. Because it has a certain flavor regulation effect, it can improve the taste and flavor of food. For example, in some fermented foods, it can promote the growth and metabolism of beneficial microorganisms, produce unique flavor substances, and enhance the flavor level of food. And its safety is high, and moderate addition is harmless to the human body, so it is gradually widely used in the food industry.

What are the physical properties of 4-aminotoluene-3-sulfonic acid?

4-Hydroxybutyric acid-3-hexenoic acid is an organic compound that has attracted much attention in the fields of chemical industry and medicine. Its physical properties are as follows:
1. ** Appearance and Properties **: Under normal conditions, 4-hydroxybutyric acid-3-hexenoic acid is a colorless to light yellow liquid with a clear and fluid appearance. This property makes it easy to mix and disperse in many reaction systems, which is conducive to participating in chemical reactions.
2. ** Odor **: emits a weak special odor, which is not pungent and malodorous, but is relatively mild. This odor characteristic is convenient for odor identification and monitoring during operation and use.
3. ** Boiling point **: The boiling point is in a specific temperature range, about [X] ° C - [X] ° C. The boiling point determines its volatilization temperature during operations such as heating or distillation, and is a key parameter in chemical processes such as separation and purification. By controlling the temperature, the effective separation of the substance from other substances with large boiling points can be realized.
4. ** Melting point **: The melting point is about [X] ° C. The melting point indicates the critical temperature at which the substance changes from solid to liquid. Knowing the melting point helps to rationally choose the packaging and storage method according to the ambient temperature conditions during storage and transportation, so as to avoid improper temperature changes that affect the quality of its state.
5. ** Solubility **: 4-hydroxybutyric acid-3-hexenoic acid has a certain solubility in water and is soluble in some organic solvents, such as ethanol, acetone, etc. Good solubility allows it to participate in the reaction in different solvent systems, expanding its application range in organic synthesis. Appropriate solvents can be selected according to reaction requirements to optimize reaction conditions, improve reaction efficiency and product purity.
6. ** Density **: The density is about [X] g/cm ³, the density reflects the mass of the substance per unit volume. During measurement and mixing operations, the dosage can be precisely controlled according to the density to ensure that the reaction is carried out according to the expected stoichiometric ratio, which is of great significance to ensure product quality and reaction effect.

Is the chemical properties of 4-aminotoluene-3-sulfonic acid stable?

The chemical properties of 4-hydroxyacetophenone-3-sulfonic acid are stable. These two are often important in the field of chemistry. 4-hydroxyacetophenone has the genus of phenolic hydroxyl and carbonyl, and the properties of these two have a huge impact on the reaction and structure of compounds. The phenolic hydroxyl group has high activity and is easy to participate in various reactions, such as esterification and etherification, and is also easily transformed by oxidants. However, its carbonyl group is not idle, and it can be added to nucleophiles, making the molecule have diverse reactions. However, in its structure, the conjugated system of benzene ring makes its electron cloud distribution uniform, which stabilizes its properties to a certain extent.
As for 3-sulfonic acid, the sulfonic acid group (-SO-H) is a strong hydrophilic group, which has strong acid properties and can ionize hydrogen ions in water, making the compound acidic. And the basic chemical stability of the sulfonic acid, high carbon-sulfur bond energy, is not easy to be broken by general reagents. When the two are connected as 4-hydroxyacetophenone-3-sulfonic acid, the properties of the two are merged. The sulfonic acid group can affect the solubility and reactivity of the molecule as a whole by virtue of its acidity and hydrophilicity, and the active group of the 4-hydroxyacetophenone part also exhibits its reactivity under specific reaction conditions.
Under normal conditions, 4-hydroxyacetophenone-3-sulfonic acid is chemically stable. When encountering strong acids, strong bases or strong oxidation or reducing agents, the active parts in its structure may react. In case of strong bases, phenolic hydroxyl groups can form phenolates; in case of strong oxidizing agents, phenolic hydroxyl groups or carbonyl groups may be oxidized. However, in a mild conventional environment, it can maintain its own structure and properties, so it can be said to be chemically stable.

What is the preparation method of 4-aminotoluene-3-sulfonic acid?

To make 4-aminobenzenesulfonic acid-3-aldehyde acid, the ancient method is as follows:
First take an appropriate amount of benzenesulfonic acid, place it in a clean kettle, cool it in an ice-water bath, and reduce the temperature in the kettle to a suitable low temperature. Slowly add the fuming sulfuric acid taken by careful measurement, add time slowly and constantly stir to prevent local overheating and cause disordered reaction. This step aims to introduce the sulfonic acid group into the sulfonic acid group at a specific position to obtain the disulfonic acid compound. After the reaction is completed, pour the reactant into a large amount of ice water, stir well, so that the product precipitates, and filter it with a Brinell funnel to obtain a filter cake. Wash it with cold water several times to remove its impurities and place it in a ventilated place to dry.
Then, take the obtained two sulfonic acid compounds, mix with an appropriate amount of concentrated nitric acid and concentrated sulfuric acid, and mix carefully. The ratio of mixed acid must be checked, and the ratio is related to the success or failure of the reaction and the purity of the product. When adding mixed acid, it is still necessary to control the temperature at low temperature, which is the key to the nitrification reaction. During the reaction, pay close attention to the temperature and reaction phenomenon in the kettle. When the reaction is complete, pour it into ice water, precipitate the product, and filter it again to obtain the nitrified product. It also needs to be washed with cold water and dried.
Then, the nitrification product is placed in a reaction system containing an appropriate amount of iron powder and hydrochloric acid. This step is a reduction reaction. The iron powder and hydrochloric acid are used as reducing agents to reduce the nitro group to an amino group. During the reaction, heat and stir moderately to promote the smooth progress of the reaction. When the reaction is over, neutralize the system with sodium hydroxide solution and adjust it to neutral. At this time, the product is either precipitated or stored in the solution. If it is precipitated, it can be obtained by suction filtration; if it is in the solution, extract it with an appropriate organic solvent, and then remove the solvent by distillation to obtain 4-aminobenzenesulfonic acid-3-aldehyde acid crude product.
Finally, the crude product needs to be refined by recrystallization and other methods. Select a suitable solvent, heat to dissolve the crude product, filter it while hot to remove insoluble impurities, let the filtrate stand and cool to precipitate the crystals, filter it again, and dry it at low temperature to obtain a pure 4-aminobenzenesulfonic acid-3-aldehyde acid.
To make this product, the reaction conditions at each step need to be precisely controlled, and the proportion of raw materials, temperature, reaction time, etc. are all key. If there is a slight difference, it will be difficult to achieve the expected effect.

What are the precautions for 4-aminotoluene-3-sulfonic acid in storage and transportation?

4-Hydroxyacetylaniline-3-sulfonic acid must pay attention to many key matters during storage and transportation.
When storing, choose the first environment. It should be selected in a cool, dry and well-ventilated place, away from fire and heat sources. This is because the substance is heated or exposed to open fire, or there is a danger. The warehouse temperature should be properly controlled, not too high, to prevent the material properties from changing. And it needs to be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed. Because of contact with it, or chemical reaction, causing the material to deteriorate and even cause safety accidents. In addition, the storage area should be equipped with suitable materials to contain leaks in case of leaks, which can be dealt with in time to avoid greater losses.
When transporting, there are also many points. Before transportation, make sure that the packaging is complete and well sealed to prevent material leakage due to package damage during transportation. Transportation vehicles should be selected that meet safety standards, and equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, the traffic should be stable to avoid bumps and shocks to prevent damage to the packaging. At the same time, they should follow the specified route and do not stop near densely populated areas and important facilities. Transportation personnel should also be familiar with the characteristics of the transported substances and emergency treatment methods. In the event of an emergency, they can respond quickly and properly. Only in this way can we ensure the safety of 4-hydroxyacetaniline-3-sulfonic acid during storage and transportation.