4-Chloro-3-(3-Methyl-5-Oxo-4,5-Dihydro-1H-Pyrazol-1-Yl)Benzenesulfonic Acid

4-Chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid, which is an organic compound. It has unique chemical properties. Looking at its structure, it is composed of benzenesulfonic acid group, chlorine atom and specific pyrazole ring structure.
Among this compound, benzenesulfonic acid group gives it a certain acidic property. Sulfonic acid group (-SO-H) is easy to dissociate hydrogen ions, so it can exhibit acidic properties under suitable conditions, and can neutralize with bases to form corresponding salts. This acidic property may play a key role in many chemical reactions and applications, such as in some catalytic reactions. The presence of chlorine atoms adds unique chemical activity to the compound. Chlorine atoms have high electronegativity, which can change the electron cloud distribution of molecules, thereby affecting their reactivity and selectivity. In nucleophilic substitution reactions, chlorine atoms can act as leaving groups to react with nucleophiles and introduce other functional groups to achieve structural modification and transformation of compounds.
And 3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl moiety, the pyrazole ring structure has a certain conjugate system, which endows the molecule with certain stability and special electronic effects. The substituents on the ring, such as methyl and carbonyl, further affect the physical and chemical properties of the molecule. Methyl is the power supply group, which can change the electron cloud density of the pyrazole ring and affect its reactivity; carbonyl has strong electron absorption, which not only affects the electron distribution of the pyrazole ring, but also may participate in various chemical reactions, such as nucleophilic addition reactions.
Overall, 4-chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid exhibits diverse chemical properties due to the synergistic effect of various parts of the structure, and may have potential applications and research values in organic synthesis, medicinal chemistry and other fields.

4-Chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid has a wide range of uses. In the field of medicinal chemistry, it can be a key intermediate for the creation of new drugs. Through delicate chemical reactions, it can be ingeniously converted into compounds with specific pharmacological activities, or can be used to fight specific diseases, such as inflammation, tumors, etc., to contribute to human health and well-being.
In the field of materials science, this substance also has its uses. Due to its special molecular structure, it may endow materials with unique properties. For example, in the preparation of some functional polymer materials, the addition of this substance may improve the stability, solubility or optical properties of the material, and then expand the application of the material in many fields such as electronics and optics.
In agricultural chemistry, its role should not be underestimated. Or it can be used as an important raw material for the synthesis of new pesticides. Through rational molecular design and synthesis, pesticide products with efficient control of crop diseases and pests can be created, and the impact on the environment is small, which contributes to the sustainable development of agriculture.
In the field of organic synthetic chemistry, it is often regarded as an important starting material or intermediate. With its lively reaction check point, chemists can follow ingenious synthesis routes to construct complex and diverse organic compounds, injecting new vitality into the development of organic synthetic chemistry and promoting the field to new heights.

To prepare 4-chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid, the method is as follows:
First, the corresponding starting materials need to be prepared, such as chlorine-containing benzenesulfonic acid derivatives and specific pyrazole derivatives. These two are the key substrates for synthesis, and their purity and quality depend on the quality of the product.
The reaction is often carried out in suitable solvents, such as polar organic solvents, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). Such solvents can effectively dissolve the substrate and promote the smooth occurrence of the reaction.
In order to make the reaction efficient, a catalyst is often introduced. Base catalysts are more commonly used, such as potassium carbonate, sodium carbonate, etc. Bases can help the nitrogen atom of pyrazole derivatives deprotonate, enhance their nucleophilicity, and then undergo nucleophilic substitution reaction with benzenesulfonic acid derivatives.
During the reaction, precise temperature control is also important. Depending on the reaction process, the initial temperature may need to be heated to a certain extent to start the reaction, which is usually controlled between 50-100 ° C. When the reaction is started, the temperature can be adjusted appropriately according to the situation to ensure the smooth progress of the reaction and avoid side reactions. During the
reaction, use thin layer chromatography (TLC) or high performance liquid chromatography (HPLC) and other monitoring methods to observe substrate consumption and product formation. When the substrate is almost exhausted and the product reaches the expected ratio, the reaction can be terminated.
After the reaction is completed, the post-treatment steps are carried out. The reaction solution is usually diluted with water first, followed by organic solvent extraction. The difference in solubility of the product and impurities in different solvents is used to achieve preliminary separation. After purification by column chromatography or recrystallization, high purity 4-chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid is obtained. Column chromatography can separate the product with a suitable eluent according to the polarity difference between the product and the impurity; recrystallization can obtain a pure crystalline product by the change of the solubility of the product in a specific solvent at different temperatures.

I don't know the price range of 4-chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid in the market. The price of this compound often changes due to various reasons. First, the price varies depending on the manufacturer. Large manufacturers may have high prices due to their excellent craftsmanship and high quality; small factories may have slightly lower prices. Second, the purchase quantity is also a major factor. If you buy in bulk, merchants may have discounts and lower unit prices; if you buy in small quantities, the price may be higher. Third, the market supply and demand situation has a great impact. If the demand is large, the supply is small, the price will rise; if the supply exceeds the demand, the price may drop. Fourth, the cost of raw materials, transportation costs, etc. also affect the price. Raw materials are expensive, transportation is far and expensive, and the price will also rise. Because there is no specific market survey and related data, it is difficult to determine its price range.

4-Chloro-3- (3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-yl) benzenesulfonic acid is a matter of safety and should be examined in detail.
In terms of its toxicity, although there is no conclusive conclusion of extreme toxicity, it may have certain effects on the organism in experiments. If it accidentally touches the skin, it may cause local discomfort, such as redness and itching. Once in the eyes, due to its chemical properties, it will irritate the eyes or damage vision, so when in contact, be sure to take comprehensive protection.
Furthermore, this substance also has potential effects in the environment. Although it is difficult to determine whether it can degrade rapidly, it will survive for a long time, or affect the surrounding ecology. If it enters the water source, the aquatic organisms may be harmed and the ecological balance may be destroyed.
When using, many precautions need to be kept in mind. Operators must wear professional protective clothing, such as protective clothing and protective gloves, which are the key to preventing skin contact. Eye protection is also indispensable, and goggles should be worn properly. Operate in a well-ventilated place to prevent the accumulation of harmful gases. After use, properly dispose of the remaining materials. Do not discard them at will. It should be handled in an environmentally friendly and safe manner in accordance with relevant regulations. The equipment used also needs to be carefully cleaned to prevent accidents caused by residual substances. Only in this way can we ensure the safety of the use process and avoid disasters.