What is the chemical structure of 4-Formyl-1,3-Benzenedisulfonic Acid, Disodium Salt Hydrate?
4-Formalyl-1,3-disodium benzenedisulfonate monohydrate, the structure of this compound is based on a benzene ring, the 1 and 3 positions of the benzene ring are connected to a sulfonic acid group (and the hydrogen of the sulfonic acid group is replaced by sodium ions, forming a disodium salt), the 4 position is connected to a formyl group, and it carries a molecule of crystal water.
From the perspective of its benzene ring, it is a six-membered carbon ring with a conjugated unsaturated structure, giving it a certain stability. The sulfonic acid group at the 1 and 3 positions is -SO 🥰 Na, and the sulfonic acid is basically hydrophilic. After forming a sodium salt, it has better solubility in water. Because the sodium salt can be ionized in water, it increases the polarity of the compound. The 4-position formyl-CHO has a typical carbonyl structure, in which the carbon-oxygen double bond makes the carbonyl carbon have a certain positive electricity, which can occur nucleophilic addition and other reactions. The crystal water and the host compound are combined with specific forces, or affect their physical properties, such as melting point, solubility, etc. This structure determines that the compound may have unique uses in organic synthesis, materials science and other fields. Due to the hydrophilicity of sulfonic acid groups and the reactivity of formyl groups, it can be used as an important intermediate for the construction of complex organic molecules, or in some material systems with specific requirements for hydrophilic and active groups.
What are the main applications of 4-Formyl-1,3-Benzenedisulfonic Acid, Disodium Salt Hydrate?
4-Formalyl-1,3-benzenesulfonate disodium salt monohydrate, which is useful in many fields. In the field of medicinal chemistry, it is often a key intermediate in drug synthesis. According to ancient sayings, it is a necessary "medicinal introduction" substance for the preparation of good medicines. It can be combined with other substances through exquisite methods to become a good medicine for treating diseases and saving people.
In the field of materials science, it may be used to prepare special functional materials. Just like the ancient craftsmen used unique things and ingenious methods to create tough and extraordinary utensils. This compound can use its characteristics to give different properties to the material, such as improving the stability and solubility of the material, etc., as if it is a special "clothing" for the material, so that it can play a unique role in specific scenarios.
In chemical production, it can be used as an auxiliary to help the chemical process smoother. Just like marching and fighting in ancient times, grain and other materials need to be properly prepared. As an auxiliary, this compound can help the reaction proceed better, improve production efficiency, and reduce production costs. It is like an indispensable help in the "battlefield" of chemical production.
What are the physical properties of 4-Formyl-1,3-Benzenedisulfonic Acid, Disodium Salt Hydrate?
4-Formalyl-1,3-disodium benzenesulfonate hydrate, which is the sodium salt form of an organic compound, often containing crystal water. Its physical properties are related to many aspects.
Looking at its morphology, it may be a crystalline solid under normal conditions. Because sodium salts have this characteristic, the molecules are maintained by ionic bonds with crystal water, forming a regular lattice structure, resulting in a crystalline state.
In terms of solubility, in view of the characteristics of sodium salts, it has good solubility in water. Sulfonic acid groups easily form hydrogen bonds with water molecules, and the hydrophilicity of sodium ions makes the compound well dispersed in water to form a uniform solution.
Melting point is also an important physical property. The intermolecular forces, including ionic bonds, hydrogen bonds, and van der Waals forces, determine the melting point. The strength of the ionic bonds is quite high, and more energy is required to destroy the lattice and melt the solid, so its melting point may be relatively high.
In terms of color, the pure material is usually white or almost white. This is because there is no conjugated system or chromophore in the molecular structure, which makes it weakly absorb visible light, so the color is light.
The determination of density requires experimental precision. According to its molecular structure and composition, the estimated density may be higher than that of ordinary organic solvents. Due to the large number of atoms in the molecule and the heavy sodium atoms, the unit volume mass increases.
The physical properties of this compound are of great significance in the fields of chemical synthesis, materials science, etc. Its good water solubility may make it a reactant or catalyst carrier in an aqueous reaction system; its higher melting point provides the possibility to maintain stability under high temperature reaction conditions; and the color and density characteristics also have important guiding value in product quality control and separation and purification.
What are the preparation methods of 4-Formyl-1,3-Benzenedisulfonic Acid, Disodium Salt Hydrate?
To prepare 4-formyl-1,3-disodium benzene disulfonate monohydrate, there are several methods.
First, resorcinol is used as the beginning, and it is obtained by formylation and sulfonation. First, resorcinol is co-heated with formic acid and concentrated sulfuric acid, and formylated to obtain 4-formyl resorcinol. After that, 4-formyl resorcinol is co-heated and sulfonated with fuming sulfuric acid to generate 4-formyl-1,3-benzene disulfonate. At the end, neutralize with sodium hydroxide, and then concentrate and crystallize to obtain 4-formyl-1,3-benzene disulfonic acid disodium salt monohydrate. In this way, the raw materials are easy to obtain, the steps are clear, but the reaction conditions are harsh, and the temperature control needs to be precise. And concentrated sulfuric acid and fuming sulfuric acid are highly corrosive, so the operation must be cautious.
Second, m-xylene is used as the raw material. First, m-xylene is oxidized by air to obtain 4-methyl-isophthalic acid. Secondary, 4-methyl-isophthalic acid reacts with sulfur trioxide and concentrated sulfuric acid to sulfonate 4-methyl-1,3-benzene disulfonic acid. Further, 4-methyl-1,3-benzene disulfonic acid is oxidized to change the methyl group to formyl group to obtain 4-formyl-1,3-benzene disulfonic acid. Finally, sodium hydroxide is used as a salt to obtain the target product. This diameter, the raw material is economical, and the oxidation and sulfonation steps are complicated, and the yield may be affected.
Third, benzene is used as the starting material. Benzene is first alkylated with chloromethane under the catalysis of anhydrous aluminum trichloride to obtain m-xylene. The subsequent steps are the same as the method using m-xylene as the starting material. In this way, the starting material is inexpensive, but the alkylation reaction conditions are high, and the recovery and treatment of the catalyst also need to be considered.
All methods for preparing 4-formyl-1,3-benzenesulfonic acid disodium salt monohydrate have their own advantages and disadvantages. The actual preparation depends on the availability of raw materials, cost, equipment conditions and yield purity requirements.
How stable is 4-Formyl-1,3-Benzenedisulfonic Acid, Disodium Salt Hydrate?
4-Formalyl-1,3-disodium benzenesulfonate monohydrate, this is a chemical substance. Its stability is related to many aspects.
In terms of thermal stability, it is easy to decompose when heated. Due to the presence of aldehyde groups (formyl groups) in the molecular structure, the aldehyde groups will undergo oxidation, polymerization and other reactions when heated. When the temperature reaches a certain level, the sulfonic acid groups will also decompose, resulting in changes in the structure of the substance.
In terms of light stability, aldehyde groups are sensitive to light. Under light, aldehyde groups are prone to photochemical reactions, or generate free radicals, which further trigger other reactions in the molecule, thereby reducing stability.
In a humid environment, as a hydrate, although it contains crystal water, if the ambient humidity is too high or too low, it may affect its stability. When the humidity is high, more water may be adsorbed and the crystal structure will be changed; when the humidity is low, the crystal water may be lost, which will affect the intermolecular force and destroy the original stable structure.
Its chemical stability also needs to be considered. The substance contains acidic groups (sulfonic acid groups). In an alkaline environment, it will neutralize with bases and change the molecular structure. In an acidic environment, it is relatively stable, but if the acidity is too strong, the aldehyde group may undergo reactions such as protonation, which will affect the stability.
In addition, in contact with other chemical substances, reactions may also occur. For example, in case of strong oxidants, aldehyde groups will be oxidized to carboxyl groups; in case of nucleophiles, aldehyde groups are prone to nucleophilic addition reactions, which will affect their stability. In short, the stability of 4-formyl-1,3-benzenesulfonate disodium salt monohydrate is restricted by many factors, and it is necessary to pay careful attention to environmental conditions and avoid contact with specific substances during storage and use.
