4-Hydroxy-3-Pyridinesulphonic Acid

4-Hydroxy-3-pyridine sulfonic acid, which has a wide range of uses. In the field of medicine, it is an important raw material for traditional Chinese medicine. Because of its specific chemical structure and activity, it can participate in a variety of drug synthesis reactions, laying the foundation for the creation of drugs for the treatment of specific diseases. In the process of drug development, it is often used as a starting material to construct molecular structures with specific pharmacological activities through a series of delicate chemical reactions.
In the field of materials science, it also plays a key role. Or can be used as a key auxiliary in the preparation of functional materials. With its unique chemical properties, it can improve some properties of materials, such as improving the stability of materials and enhancing their compatibility with other substances. For example, in the synthesis of polymer materials, the addition of this compound in an appropriate amount may significantly improve the mechanical properties and thermal stability of the material, thereby broadening the application scenarios of the material.
Furthermore, in the field of chemical production, it is also an indispensable intermediate. It can participate in many organic synthesis reactions and generate various chemical products with different functions through a series of transformations. For example, in the synthesis of fine chemicals such as dyes and fragrances, it plays an important role in the diversification and high performance of chemical products.
In summary, 4-hydroxy-3-pyridine sulfonic acid has shown important uses in many fields such as medicine, materials science, and chemical production due to its unique chemical properties, which is of great significance for promoting the development of related industries.

4-Hydroxy-3-pyridine sulfonic acid is a kind of organic compound. Its physical properties are particularly important, and it is related to its application in various fields.
First of all, its appearance, under room temperature and pressure, 4-hydroxy-3-pyridine sulfonic acid is often white to light yellow crystalline powder shape, fine and uniform texture, pure color, no variegated patches. This form is conducive to its storage, transportation and subsequent processing operations. Because of its powder shape, it is easy to disperse and mix, and it is quite convenient to use in preparations and other links.
Second, its solubility. This substance is soluble in water, and can be well dispersed and dissolved in water to form a uniform solution. This property makes it very useful in chemical reactions and drug formulations of many aqueous systems. It is soluble in water, which means that water can be used as a medium to participate in various reaction processes, or as a component of drug carriers to help drugs transport and absorb in vivo. However, its solubility in organic solvents varies depending on the type of solvent. In polar organic solvents such as methanol and ethanol, it also has a certain solubility, which can be moderately dissolved and dispersed; but in non-polar organic solvents such as n-hexane and benzene, the solubility is extremely low, or even almost insoluble. This difference in solubility is of great reference value in the separation, purification and construction of specific reaction systems.
Furthermore, 4-hydroxy-3-pyridine sulfonic acid has a certain melting point. Its melting point is stable and within a certain range (the specific value fluctuates slightly depending on factors such as purity). The melting point is a key indicator for identifying the purity of the substance and determining its thermal change characteristics. When heated to the melting point, the substance gradually melts from a solid state to a liquid state. This process requires a certain amount of heat to be absorbed, and the transformation process is relatively clear and discernible. By accurately measuring the melting point, the purity of the substance can be judged. If the purity is high, the melting point range is narrow and approaches the theoretical value; if it contains impurities, the melting point decreases and the melting range becomes wider.
In addition, its density is also an important physical property. Under certain conditions, 4-hydroxy-3-pyridine sulfonic acid has a specific density value. This density parameter is indispensable in terms of material quantification, mixing ratio and related engineering design. For example, when preparing a solution of a specific concentration, the dosage should be accurately calculated according to the density; in the design of chemical production pipelines, density is also an important basis for considering fluid transportation and other issues.
In short, the physical properties of 4-hydroxy-3-pyridine sulfonic acid, from appearance, solubility, melting point to density, are interrelated and important, and together determine its application characteristics and scope in many fields such as chemistry, medicine, materials, etc.

To prepare 4-hydroxy-3-pyridine sulfonic acid, the method is as follows:
First, pyridine is used as the starting material, and the pyridine ring has special chemical activity, which can lead to reactions. In an appropriate reaction bottle, an appropriate amount of pyridine is placed, and sulfuric acid is used as the sulfonation agent. Sulfuric acid has strong acidity and sulfonation ability. The reaction needs to be controlled at temperature. At the beginning, sulfuric acid is slowly added at low temperature. Due to the exothermic reaction of the sulfonation reaction, if the temperature is too high, it is easy to cause side reactions to occur. In this process, the sulfuric group of sulfuric acid (-SO 🥰 H) attacks the pyridine ring, and the electron cloud of the epyridine ring is distributed. The sulfuryl group is mostly substituted in the
However, the hydroxyl group is not obtained at this time. In the following steps, 3-pyridine sulfonic acid can be oxidized with an appropriate oxidizing agent, such as hydrogen peroxide, in the presence of a specific catalyst. Due to the presence of a sulfonyl group at the 3rd position on the pyridine ring, the electron cloud density at the ortho (4th position) is changed, which is conducive to the introduction of hydroxyl groups. After oxidation, the hydroxyl group is introduced at the 4th position, and the final 4-hydroxy-3-pyridine sulfonic acid is obtained.
After the reaction is completed, the product needs to be separated and purified. By recrystallization, a suitable solvent can be selected to dissolve the product in it, but the impurities are insoluble or insoluble. After filtering and removing impurities, the Column chromatography can also be used to select a suitable stationary phase to achieve the purpose of separation and purification according to the difference in adsorption and elution between the product and impurities. In this way, a relatively pure 4-hydroxy-3-pyridine sulfonic acid can be obtained.

4-Hydroxy-3-pyridine sulfonic acid, the price of this product in the market is really difficult to determine. The price of this product often changes due to various reasons, such as the quality of the goods, the trend of supply and demand, the increase or decrease of manufacturing costs, and even the flow of time.
Looking at the past, if the supply in the city exceeds the demand, the price may decline; if the demand exceeds the supply, the price will be easy to rise. And those with good quality, the price is always higher than that of regular products. The manufacturing cost is also the main reason. If the raw materials are difficult to find and the process is complicated, the cost will be high, and the price will follow.
As for "Tiangong Kaiwu", it records all the craftsmanship and creations in detail, but it does not involve the price of this product. There was no such thing at that time, or it was not valued in the book. If you want to know its market price now, you should carefully observe the current chemical market and ask the merchants in the industry to obtain a more accurate number, and it is advisable to observe the changes in the market before you can know the ups and downs of its price.

4-Hydroxy-3-pyridine sulfonic acid, this is a very important chemical substance. During use, many matters need to be paid attention to.
Those who bear the brunt must be well protected. Because it may be corrosive and irritating, protective equipment is essential when coming into contact. Operators should wear protective clothing, protective gloves on their hands, and protective glasses on their eyes to prevent them from coming into direct contact with the skin and eyes. If they come into contact accidentally, they should rinse with plenty of water immediately and seek medical attention in time.
Furthermore, the storage process should not be ignored. Store it in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties or relative activity, improper storage conditions or deterioration will affect the use effect. Store separately from oxidants, acids, bases, etc., and must not be mixed to avoid dangerous chemical reactions.
When using, it is crucial to precisely control the dosage. According to specific reaction requirements and process requirements, accurately weigh the required dosage. Too much or too little dosage may have an adverse impact on the reaction process and product quality. At the same time, the reaction conditions such as temperature and pH value also need to be strictly controlled. Due to its reactivity or being significantly affected by such conditions, suitable reaction conditions can ensure the smooth progress of the reaction and obtain the ideal product.
In addition, after use, it is crucial to properly dispose of the remaining substances and waste. Do not discard it at will, follow relevant environmental protection regulations, and carry out harmless treatment to avoid pollution to the environment. Throughout the use process, operators should also be familiar with relevant emergency plans. In the event of an accident, they can respond quickly and correctly to ensure personnel safety and environmental safety.