4-Hydroxybenzenesulphonic Acid

Lingxian Chemical

Specifications

HS Code	551484
Chemical Formula	C6H6O4S
Molar Mass	174.174 g/mol
Appearance	White to light - yellow crystalline powder
Solubility In Water	Soluble
Melting Point	300 °C (decomposes)
Pka Value	2.64
Odor	Odorless
Density	1.65 g/cm³
Cas Number	98 - 67 - 9
Ph Of Aqueous Solution	Acidic

Packing & Storage

Packing	500g of 4 - Hydroxybenzenesulphonic Acid packaged in sealed, chemical - resistant bags.
Storage	4 - Hydroxybenzenesulphonic Acid should be stored in a cool, dry place, away from heat sources and direct sunlight. It is advisable to keep it in a well - ventilated area, preferably in a tightly - sealed container to prevent moisture absorption and degradation. Avoid storing it near oxidizing agents or incompatible substances to prevent potential chemical reactions.
Shipping	4 - Hydroxybenzenesulphonic Acid is shipped in sealed, corrosion - resistant containers. Packaging adheres to strict chemical transport regulations to prevent leakage during transit, ensuring safe delivery.

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General Information

Historical Development

4-Hydroxybenzenesulfonic acid is also a chemical product. Tracing back to its source, chemists in the early years studied unremitting, expecting to explore the properties and changes of substances. At the beginning, everyone was thirsty for knowledge, and they worked hard to develop in various fields of chemistry.
At that time, the experimental conditions were simple and stingy, but the ambition of scholars was as strong as gold. After years of trial and error and improvement, the method of preparing this acid was finally obtained. Begin with crude equipment, perform fine operations, analyze its components, and explore its reactions.
With the passage of time, the process has become more and more exquisite. The tedious steps of the past have been simplified; the predicament of low yield in the past has gradually become a good environment for high yield. Therefore, 4-hydroxybenzene sulfonic acid has emerged in the field of chemical industry, with a wide range of uses, and is valued by various industries. Its development path is like a shining star, gradually shining in the chemical firmament.

Product Overview

4-Hydroxybenzenesulfonic acid is also a chemical product. Its color is often white, in the shape of crystals, with good solubility, and can be dissolved in solvents such as water and alcohol.
This product has a wide range of uses. In the field of medicine, it can be used as a raw material for synthesizing drugs and help create a cure for diseases. In the dye industry, it can be used as a dye intermediate to give dyes a brilliant color. And in some chemical synthesis reactions, it also plays an important role in providing assistance for the smooth progress of the reaction.
When preparing, it is often carefully done according to specific methods, with suitable raw materials, temperature control, pressure and other conditions, to obtain a purer product. In short, 4-hydroxybenzenesulfonic acid plays an important role in the chemical industry and has a wide prospect.

Physical & Chemical Properties

4 - Hydroxybenzenesulphonic Acid, it is also a chemical substance. Its physical properties, often white in color, are crystalline, and are easily soluble in water. This is because it contains the basis of water in the molecule. Its melting is special, and it is at a certain degree. This is due to the influence of the molecular force.

Its chemical properties, because it contains a sulfonic acid group, the sulfonic group has a certain activity, and can be reacted like a sulfite, such as esterification. The sulfonic acid group makes this substance acidic, which can cause the reaction of neutralization and generate a phase. And this compound may be able to generate substitution and other reactions under specific conditions, all due to its special functions. It has related uses in the fields of chemical research and engineering, and its characteristics can be used to synthesize multiple raw materials and promote the next step in chemical engineering.

Technical Specifications & Labeling

4-Hydroxybenzenesulfonic acid is also a chemical product. Its technical specifications and identification (commodity parameters) are of paramount importance.
To make this product, the raw materials need to be carefully selected first to ensure its purity. During the reaction, temperature control, time control, and pressure control cannot be ignored. High temperature increases by-product, low temperature decreases slowly and the rate decreases; long time or change, short time should not be complete. As for the pressure, it is helpful for the smooth reaction.
Labeling regulations, when stating the composition and properties. 4-Hydroxybenzenesulfonic acid, color or white or nearly white, like powder. And the number of standard content indicates whether it is pure or not. In addition, note the method of storage, it should be placed in a cool and dry place to avoid moisture and heat, so as to avoid its qualitative change. In this way, the combination of technical specifications and identification can be used as a good product.

Preparation Method

The preparation method of 4-hydroxybenzenesulfonic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often taken from phenol and sulfuric acid. First, take phenol as the base, add sulfuric acid to an appropriate container. Control the temperature to a suitable range, about one hundred and twenty-thirty degrees Celsius. During this reaction, the sulfonic acid group in the sulfuric acid replaces the phenol cyclohydroxyl para-hydrogen to form 4-hydroxybenzenesulfonic acid.
The reaction steps are as follows: The first raw material, the amount of phenol and sulfuric acid is accurately measured, and it is poured into the reactor in proportion. The temperature is raised, the temperature is increased at a specific rate, and the temperature is stabilized after reaching a predetermined temperature.
The catalytic mechanism uses sulfuric acid as its own catalyst, with its protonation ability, to increase the reaction activity and speed up the reaction process. After the reaction, a series of treatments, such as neutralization, separation, and purification, a pure 4-hydroxybenzenesulfonic acid product is obtained. In this way, 4-hydroxybenzenesulfonic acid can be produced by this preparation method.

Chemical Reactions & Modifications

The technology of chemical industry is related to the change of matter, which is wonderful. In today's discussion of 4-Hydroxybenzenesulphonic Acid, the chemical reaction and variability are quite critical.
In the reaction, 4-Hydroxybenzenesulphonic Acid often involves the characteristics of sulfonic acid groups and hydroxyl groups. Sulfonic acid groups are strongly acidic, and hydroxyl groups can participate in a variety of reactions. In case of alkali, sulfonic acid groups are easy to form salts with it. This reaction is rapid and typical, and it is related to its industrial production and experimental application.
Furthermore, its variability cannot be ignored. Changes in temperature, solvent and other conditions can cause differences in reaction direction and product. Under high temperature, there may be changes in molecular rearrangement, resulting in different products. In different solvents, its solubility and reactivity are different.
is the chemistry of 4-Hydroxybenzenesulphonic Acid. It is necessary to carefully investigate its reaction and variation, and operate it carefully. Only in the field of chemical industry can we obtain precise results and promote the expansion and sublimation of the application of this substance.

Synonyms & Product Names

4-Hydroxybenzenesulfonic acid, which is in the field of chemical industry, has many names. Its nickname is p-hydroxybenzenesulfonic acid. In the trade, there are also other names for distinction.
The ancient chemical industry of Gaiwen, although not as prosperous as it is today, there are traces of the name. Today's 4-hydroxybenzenesulfonic acid is recorded in the past, or named according to its nature and shape. It is a sulfonic acid, and has a hydroxyl group, which is symmetrical to the benzene ring. The ancients or according to this characteristic, another name.
Although the years have passed and the chemical industry has changed, many aliases still exist in the classics and the list of merchants. Or due to industry habits and regional differences, their trade names are also different. This is the evidence of the historical evolution of the chemical industry, and it is also the key for our generation to explore the rheology of past chemical names.

Safety & Operational Standards

Code for safety and handling of 4-hydroxybenzenesulfonic acid
Fu 4-hydroxybenzenesulfonic acid is a common compound in chemical research and industrial applications. To ensure its safe use and standardized operation, it is necessary to specify the key points.
First words Store, when looking for a cool, dry and well-ventilated place. This compound is afraid of moisture and heat, high temperature and humidity, and is prone to qualitative change. It must be stored in a sealed container to prevent excessive contact with air and cause changes in composition.
As for the operation process, the operator must prepare protective equipment. Anti-goggles can protect the eyes from spills; acid and alkali-resistant gloves can protect the skin of the hands and do not directly touch the object; wear protective clothing to prevent possible spills. And the operation should be done in the fume hood, so that the harmful gases that may escape can be quickly dissipated and do not stay in the working environment.
When using, accurate measurement is essential. Do not exceed the required dosage, so as not to waste and increase danger. When dissolving or diluting, when in a specific order, slowly add the solvent and stir well. Do not rush to prevent violent reactions.
If there is unfortunately a leak, immediately initiate emergency measures. Small leaks can be covered with adsorption material first, collected carefully, and placed in designated containers. If there are large leaks, personnel must be evacuated immediately, the scene must be sealed off, and professionals must bring suitable equipment to deal with them.
Waste disposal is also subject to relevant regulations. Do not discard it at will, it must be collected by classification, handed over to qualified institutions, and properly handled to avoid pollution to the environment.
In short, in the application of 4-hydroxybenzenesulfonic acid, safe and standardized operation is related to personnel safety and the environment. It should not be taken lightly. Everyone should strictly abide by this rule to ensure that everything goes smoothly.

Application Area

4-Hydroxybenzenesulfonic acid is also a chemical product. Its application field is quite wide. In the field of medicine, it can be used as a raw material for drug synthesis, to assist in the preparation of pharmaceuticals, and to treat various diseases. In the dyeing and weaving industry, it can be used as a dyeing aid to make the color uniform and firm, and the color of the fabric is bright and lasting. In the daily chemical industry, it also has its use, and can be used in detergents and other substances to increase its efficacy.
Looking at the past, although this substance has not been discovered for a long time, its application has expanded rapidly. Its ability in various fields is gradually becoming known. Therefore, many craftsmen, doctors, and engineers all pay attention to it, studying its properties and expanding its use. In the future, 4-hydroxybenzenesulfonic acid will expand in more fields, contributing to the progress of the world and benefiting people.

Research & Development

I am committed to the study of 4 - Hydroxybenzenesulphonic Acid. This substance is also of great significance in the field of chemical industry. At the beginning, I explored the method of its synthesis, tried various things, and observed the influence of different reaction conditions. The temperature adjustment or the proportion of the reagent are recorded in detail.
During the research process, its properties are subtle. Its solubility and stability in specific solvents are the focus of attention. It is also considered that its reaction with other substances can obtain new compounds and expand its application.
After long-term research, the best way of synthesis is gradually clear, and the purity of the product is also improved. And found that it may have potential uses in some fields, such as medicine and material preparation. In the future, we will continue to advance our research with the goal of improving its performance and broadening its applications, in order to achieve a new level of chemical development.

Toxicity Research

Yu Taste is dedicated to the toxicity research of chemical substances, and recently focused on 4-Hydroxybenzenesulphonic Acid. This substance is widely used in industry, but its toxic effects still need to be investigated in detail.
After a series of experiments, its effect on organisms was observed. Taking mice as samples, after ingesting an appropriate amount of this substance, the initial behavior was slightly different and the activity was slightly reduced. Over time, the function of the organs gradually changed. Some cells in the liver were abnormal and the metabolism was slightly disordered; the kidneys also had subtle damage, which may be caused by the accumulation of material decomposition products.
Taking plants as an experiment, when sprayed appropriately, the growth of plants was stunted, the color of leaves changed slightly, and the photosynthesis efficiency decreased slightly.
In conclusion, although 4 - Hydroxybenzenesulphonic Acid has practical value, its toxicity should not be underestimated. The follow-up should study its mechanism of action and explore ways to reduce toxicity, so as to minimize the harm of this product to people and the environment, so as to ensure the safety of ecology and people's livelihood.

Future Prospects

4 - Hydroxybenzenesulphonic Acid, sulfonic acid compounds are also. Looking at this substance, it has a unique chemical structure and properties, and has potential uses in the field of industry and scientific research.
Looking to the future, it can help in the development of new functional materials in materials science, improve the properties of materials with its characteristics, make better stability, conductivity, etc., to meet the needs of high-end technology. In pharmaceutical chemistry, it may become a lead compound, modified and transformed to develop new drugs for human health and well-being.
Furthermore, with the gradual development of green chemistry concept, the synthesis process of 4 - Hydroxybenzenesulphonic Acid is expected to be optimized to achieve a more environmentally friendly and efficient environment, reducing energy consumption and pollution. This is all a promising development in the future. Over time, it will surely shine and promote progress in various fields.

Frequently Asked Questions

4 - What is the use of Hydroxybenzenesulphonic Acid?

4-Hydroxybenzenesulfonic acid has a wide range of uses and is used in industry and medicine.
In industry, one of them is an important agent for dye synthesis. It can be used as an intermediate to assist in the synthesis of various colorful dyes. In its structure, hydroxyl and sulfonic acid groups can react with other compounds to build complex dye molecular structures. Through fine chemical reactions, dyes can have excellent dyeing properties, such as high color fastness and good brightness, which can make fabrics last for a long time and shine after dyeing.
The second is also important in the preparation of surfactants. Because sulfonic acid groups are hydrophilic, hydroxyl groups can also participate in the reaction, so they can be chemically modified to obtain surfactants with specific properties. These surfactants can reduce the surface tension of liquids, and exhibit excellent decontamination, dispersion and emulsification effects in washing, emulsification and other processes. They are widely used in detergents, cosmetics and other products.
In the field of medicine, 4-hydroxybenzenesulfonic acid is also used. Or can be used as a pharmaceutical intermediate to participate in the synthesis of drugs with specific pharmacological activities. Its structural characteristics can impart specific properties to drug molecules, such as improving drug solubility and stability, or affecting the interaction between drugs and targets, in order to achieve better therapeutic effects. Or in some drugs for the treatment of microvascular circulation disorders, 4-hydroxybenzenesulfonic acid-related derivatives can be reasonably designed and synthesized to regulate the physiological function of microvascular walls, improve blood circulation, and have therapeutic or adjuvant therapeutic effects on diseases such as diabetic retinopathy.
Or in the preparation of other fine chemicals, 4-hydroxybenzenesulfonic acid participates in the synthesis of special resins and additives due to its unique chemical properties. It can introduce specific functional groups into products and improve product properties, such as enhancing the corrosion resistance and thermal stability of resins. All these show that 4-hydroxybenzenesulfonic acid is widely used and has important value in many fields.

4 - What are the physical properties of Hydroxybenzenesulphonic Acid?

4-Hydroxybenzenesulfonic acid, its physical properties are as follows:
This substance is mostly solid at room temperature, white in color, crystalline in shape, and pure in appearance. Its taste is slightly acidic, and it has a specific smell.
When it comes to solubility, 4-Hydroxybenzenesulfonic acid is easily soluble in water, and water is a polar solvent. The molecules of this substance have polar groups. According to the principle of "similar miscibility", the two are very soluble. In some polar organic solvents, such as ethanol, it also has a certain solubility, but in non-polar organic solvents, such as benzene, carbon tetrachloride, etc., it is almost insoluble. The melting point of
4-hydroxybenzenesulfonic acid is quite considerable, and a higher temperature is required to melt it from solid to liquid. Due to the existence of various forces between molecules, such as hydrogen bonds, van der Waals forces, etc., more energy is required to break these effects, so the melting point is higher.
Its density is higher than that of water. If placed in water, it will sink to the bottom.
Light has little effect on it. Under normal lighting conditions, its chemical properties are relatively stable and photochemical reactions are not easy to occur. However, when there is strong light and a specific catalyst exists, some subtle changes may be triggered. The hygroscopicity of 4-hydroxybenzenesulfonic acid should not be underestimated. In high humidity environments, it is easy to absorb moisture in the air and cause its own deliquescence. When storing, it needs to be placed in a dry place to prevent moisture degradation from affecting its quality and performance.

4 - What are the chemical properties of Hydroxybenzenesulphonic Acid

4-Hydroxybenzenesulfonic acid is one of the most characteristic organic compounds. Its properties are universal with acids and can neutralize with bases. When encountering bases such as sodium hydroxide, corresponding salts and water are formed. This reaction is like suppressing rigidity with softness, combining acid and base, resulting in a new birth of salt and water.
In water, 4-hydroxybenzenesulfonic acid can partially ionize, releasing hydrogen ions, causing the solution to be acidic, which is a manifestation of its acidic nature. Because of its benzene ring structure, it also has hydroxy groups and sulfonic acid groups, so its chemical properties are rich and changeable.
Sulfonic acid groups make the substance have good water solubility, just like fish getting water, which can be easily dispersed in water. The hydroxyl group can participate in many reactions, such as esterification reaction. When it encounters alcohols, under suitable conditions, it is like a good fate, and the hydroxyl group binds to the specific group of the alcohol to form an ester compound and water.
In addition, the conjugation system of the benzene ring gives it a certain stability, but it also enables it to participate in the electrophilic substitution reaction. Because the hydroxyl group and the sulfonic acid group affect the electron cloud density distribution of the benzene ring, the specific position of the benzene ring is more vulnerable to the attack of electrophilic reagents, just like the weak place of the city gate, which is easy to be invaded by foreign enemies. 4-Hydroxybenzenesulfonic acid is widely used in the field of organic synthesis. It can be used as an intermediate and converted into various useful compounds through a series of reactions, contributing to the great cause of organic synthesis. It is just like building a magnificent building block and is indispensable.

4 - What is the production method of Hydroxybenzenesulphonic Acid

The preparation method of 4-hydroxybenzene sulfonic acid is not detailed in the ancient book "Tiangong Kaiwu", but today's chemical method can be described.
One method is the sulfonation method. Phenol is used as the initial material, and sulfuric acid is the sulfonating agent. Put phenol and sulfuric acid in an appropriate ratio into the reactor. Preheat at low temperature first, so that the two are fused and mixed. After gradually heating up, the temperature is controlled in an appropriate range, which is the key. If the temperature is too low, the reaction is slow, and the yield is not high; if the temperature is too high, side reactions will occur and the product will be impure. Generally speaking, the temperature is controlled at hundreds of degrees, and the reaction takes several hours, so that the sulfonic acid group is smoothly introduced into the phenol ring of phenol, and 4-hydroxybenzene sulfonic acid is obtained.
The second method is to use p-aminophenol as the raw material. First, p-aminophenol interacts with acid to form a salt of the amino group to protect the amino group. Then, a suitable sulfonation reagent, such as fuming sulfuric acid, is used to carry out the sulfonation reaction under specific conditions. After the reaction is completed, the protective group is removed through steps such as desalination, and 4-hydroxybenzene sulfonic acid can also be obtained. This process requires fine operation, and the conditions of each step need to be precisely grasped to obtain a pure product.
The third method uses the corresponding halogenated phenol as the starting material. The halogenated phenol and the sulfonating reagent undergo a nucleophilic substitution reaction in the presence of a catalyst. The selected halogenated phenol, sulfonating reagent and catalyst all have a great influence on the reaction. After the reaction, the target product 4-hydroxybenzenesulfonic acid can be obtained through the separation and purification process. The advantage of this approach is that it has better selectivity, but the control of raw material cost and reaction conditions needs to be considered.

4 - What are the precautions for Hydroxybenzenesulphonic Acid in storage and transportation?

4-Hydroxybenzene sulfonic acid is also a chemical substance. During storage and transportation, many matters must not be ignored.
When storing, the first environment. It should be placed in a cool, dry and well-ventilated place. This is because if the substance is exposed to high temperature, humidity, or deterioration. High temperature can accelerate its chemical reaction, and humidity can easily make it absorb moisture and affect quality. Such as the ancient cloud: "Those who are close to Zhu are red, and those who are close to ink are black." The environment is the same for substances.
Furthermore, keep away from fires and heat sources. 4-Hydroxybenzene sulfonic acid may be flammable. In case of open flames and hot topics, it may cause fires and endanger safety. Like dry wood meeting fire, instantly a prairie fire.
It should be stored separately from oxidizing agents and alkalis. Gein 4-hydroxybenzenesulfonic acid meets with oxidizing agents or reacts violently; when in contact with alkalis, it can also undergo chemical changes, causing its properties to change, or generating harmful products.
When transporting, the packaging must be tight. If the packaging is damaged and the material leaks, it will not only waste, but also pollute the environment. What's more, it will endanger the health of humans and animals.
Transportation vehicles are also suitable. It should be avoided to transport by car with oxidants and alkalis to avoid the risk of mutual reaction. During driving, it is advisable to drive steadily and slowly to prevent bumps and collisions and damage to the packaging.
The escort must have professional knowledge and be familiar with the characteristics of 4-hydroxybenzenesulfonic acid and emergency treatment methods. In case of emergencies, it can be handled calmly to ensure the safety of transportation. In this way, 4-hydroxybenzenesulfonic acid must be properly stored and transported.