What are the main uses of 4-Methylbenzenesulfonic Acid 2- [2-Oxo-1-Phenyl-2- (1-Piperidinyl) Ethylidene] Hydrazide
4-Methylbenzenesulfonic acid-2 - [2-oxo-1-phenyl-2 - (1-piperidinyl) ethylene] hydrazide has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help develop drugs with specific biological activities. Due to its unique structure, it can interact with specific targets in organisms, or be helpful in the treatment of certain diseases, such as antibacterial, anti-inflammatory or anti-tumor.
In the field of materials science, it may be used to prepare functional materials. With its special chemical structure, it can participate in material synthesis reactions, endowing materials with unique properties such as enhanced stability and specific adsorption properties, and is used in fields such as separation membrane materials and adsorbents.
It also plays an important role in the field of organic synthesis. As an organic synthesis reagent, it can participate in many organic reactions to construct more complex organic molecular structures, providing organic synthesis chemists with rich synthesis strategies and paths to expand the variety and function of organic compounds.
In summary, 4-methylbenzenesulfonic acid-2 - [2-oxo-1-phenyl-2 - (1-piperidinyl) ethylene] hydrazide has shown important uses in many fields such as medicine, materials and organic synthesis, and the prospects are quite promising.
4-Methylbenzenesulfonic Acid 2- [2-Oxo-1-Phenyl-2- (1-Piperidinyl) Ethylidene] Hydrazide
4-Methylbenzenesulfonic acid 2 - [2-oxo-1-phenyl-2 - (1-piperidinyl) ethylene] hydrazide, the composition of this compound, is composed of several groups.
Among them, the 4-methylbenzenesulfonic acid part contains a benzene ring structure, and the benzene ring is connected with methyl (-CH 🥰) and sulfonic acid (-SO 🥰 H). Methyl is an alkyl group, which has a certain electron supply effect and can affect the electron cloud density of the benzene ring; the sulfonic acid group gives the compound an acidic characteristic.
And 2- [2-oxo-1-phenyl-2- (1-piperidinyl) ethylene] hydrazide moiety, containing phenyl group, endows the compound with a certain conjugate system and hydrophobicity; 2-oxo structure is carbonyl (C = O), which has polarity and has a great influence on the physical and chemical properties of the compound; 1-piperidinyl is a nitrogen-containing heterocyclic ring, and the nitrogen atom on the piperidine ring can participate in the formation of hydrogen bonds or chemical reactions; ethylene is the connecting structure, which plays the role of connecting the groups; the hydrazide moiety (-CONHNH ²), which contains both carbonyl and hydrazine, and the nitrogen atom in the hydrazine group Hydrogen has certain reactivity and can participate in a variety of chemical reactions, such as the formation of hydrazone compounds by reacting with alaldehyde and ketone.
In summary, this compound is composed of a variety of specific structural groups mentioned above, and each group interacts to give it unique chemical and physical properties.
What is the preparation method of 4-Methylbenzenesulfonic Acid 2- [2-Oxo-1-Phenyl-2- (1-Piperidinyl) Ethylidene] Hydrazide
To prepare 4-methylbenzenesulfonic acid 2- [2-oxo-1-phenyl-2- (1-piperidinyl) ethylene] hydrazide, the method is as follows:
First take an appropriate amount of 1-phenyl-2- (1-piperidinyl) ethyl ketone and place it in a clean reaction vessel. This ketone needs to be carefully purified to ensure that the reaction is pure and free of impurities. Then, slowly add an appropriate amount of hydrazine compounds, such as anhydrous hydrazine, and the ratio of the two should be precisely prepared to achieve the best reaction effect. During the reaction, it is necessary to control the temperature within a suitable range. The method of water bath or oil bath can be used to make the temperature stable and not fluctuate greatly. Continuous stirring is required to fully contact the reactants and accelerate the reaction process.
After the above reaction is completed, the intermediate product is obtained, and another 4-methylbenzenesulfonyl chloride is taken and placed in another clean container. The temperature of this container is adjusted to a specific range, and then the intermediate product obtained before is slowly added dropwise. When adding dropwise, be sure to pay attention to the speed, not too fast, so as not to overreact. At the same time, add an appropriate amount of acid binding agent, such as triethylamine, to neutralize the acid generated by the reaction and promote the positive progress of the reaction.
After the reaction is completed, the resulting mixture The method of extraction can be used to extract the target product to the organic phase with a suitable organic solvent, such as ethyl acetate, multiple times to transfer the target product to the organic phase. After that, the organic phase is washed to remove impurities, which can be washed several times with saturated salt water. Then the organic phase is dried with anhydrous sodium sulfate, the desiccant is filtered off, and the organic solvent is distilled under reduced pressure to obtain a crude product.
Finally, the crude product is recrystallized, a suitable solvent is selected, such as ethanol-water mixed solvent, and careful operation is performed to crystallize the product, filter and dry it, resulting in pure 4-methylbenzenesulfonic acid 2 - [2-oxo-1-phenyl-2 - (1-piperidinyl) ethylene] hydrazide. The whole process requires rigorous operation and attention to the details of each step to obtain a satisfactory product.
4-Methylbenzenesulfonic Acid 2- [2-Oxo-1-Phenyl-2- (1-Piperidinyl) Ethylidene] Hydrazide
4-Methylbenzenesulfonic acid 2 - [2-oxo-1-phenyl-2 - (1-piperidinyl) ethylene] hydrazide This substance may have various unsuitable effects. When the chemical agent is not known, it is used rashly, and it may cause disaster.
Look at its structure, containing sulfonic acid, hydrazide and other groups. Sulfonic acids, many of which are acidic, encounter alkali or active metals, often neutralize and replace, generate heat or generate gas, and in the sealed place, it is easy to cause pressure rise, leading to the risk of explosion. The genus of hydrazide is active in nature and sensitive to oxidants. The two are combined in one place, or cause severe reactions, releasing a large amount of heat and gas. If it is not protected, it will hurt people, destroy and utensils.
And its piperidine and phenyl structure, the organic composition is complex, or under specific conditions, rearrangement and polymerization make the product impure and lose its original effect. And this thing or with common things in the environment, such as moisture and oxygen, gradually changes, causing instability in nature, long-term survival and deterioration.
When used in experiments and production, its chemical properties need to be detailed, and comprehensive protection should be made in advance to control the reaction conditions to prevent accidental reactions, so as to ensure safety and obtain expected results. Otherwise, if the operation is not careful, it will cause trouble that is difficult to measure and endanger everything.
4-Methylbenzenesulfonic Acid 2- [2-Oxo-1-Phenyl-2- (1-Piperidinyl) Ethylidene] Hydrazide is available in the market
I don't know how much 4 - Methylbenzenesulfonic Acid 2 - [2 - Oxo - 1 - Phenyl - 2 - (1 - Piperidinyl) Ethylidene] Hydrazide is priced in the market. The price of this chemical material often varies for many reasons. First, the difficulty of production is different. If the preparation requires difficult processes and rare raw materials, the price will be high. Second, the trend of supply and demand is also the key. If there are many applicants and few suppliers, the price will rise, and vice versa. Third, the quality has a shallow impact. Those with high purity and excellent quality should be more expensive than those with ordinary prices.
And the market conditions are changing rapidly, and prices vary from place to place. If you want to know the exact price, you can consult the suppliers of chemical raw materials, such as chemical product trading houses, who often know the current price. Or on the platform of chemical product trading, you can check the prices quoted by people to get a rough idea. I regret that I can't state the price directly. I hope this will help you in your quest for knowledge.