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What is the chemical structure of (4-Nitrophenyl) Benzenesulfonate?
The chemical structure of (4-nitrophenyl) benzenesulfonate is one of the important topics involved in the field of organic chemistry. The structure of this compound includes the basic structure of monobenzenesulfonate, the benzenesulfonate part, which is formed by connecting the benzene ring to the sulfonate group. Sulfonate group, -SO 2O OR, where the R part is in the (4-nitrophenyl) benzenesulfonate, which is 4-nitrophenyl group.
The part of 4-nitrophenyl group is formed by introducing nitro (-NO 2O) at the para-position of the benzene ring (ie, position 4). Nitro is a strong electron-absorbing group, and its existence can significantly affect the electron cloud distribution of the whole molecule, which in turn has many effects on the physical and chemical properties of the compound.
As far as the overall structure is concerned, the benzene ring of benzenesulfonate and the benzene ring of 4-nitrophenyl group are related to each other and together form the core carbon skeleton of the compound. Such structures are often used in organic synthesis, pharmaceutical chemistry and other fields. Due to their specific electronic and spatial structures, they can participate in many chemical reactions, exhibit unique reactivity and selectivity, and provide a key structural basis for the design and synthesis of more complex organic molecules.
What are the main uses of (4-Nitrophenyl) Benzenesulfonate?
(4-Nitrophenyl) benzenesulfonate, which is an important chemical substance in the field of organic synthesis, has a wide range of uses.
First, in the field of medicinal chemistry, it is often used as an intermediate to synthesize various drugs. Drug synthesis is like a delicate building, and (4-nitrophenyl) benzenesulfonate is like a key masonry. It can use specific chemical reactions to cleverly connect with other compounds to construct drug molecular structures with specific pharmacological activities. For example, in the synthesis of some antibacterial drugs, it can participate in the reaction and introduce key groups to enhance the drug's ability to inhibit or kill bacteria.
Second, it also has important functions in the field of materials science. In the preparation of high-performance polymer materials, (4-nitrophenyl) benzenesulfonate can be used as a modifier. As if imparting special "magic" to the material, the modified polymer may have significant improvements in heat resistance and mechanical properties. For example, high-performance materials used in the aerospace field can better adapt to extreme environments after modification.
Third, in the study of organic synthesis chemistry, (4-nitrophenyl) benzenesulfonate is often used as a reaction substrate to help chemists explore new reaction paths and methods. By manipulating it to participate in different reactions, observing reaction phenomena and products, chemists are like exploring unknown treasures, constantly expanding the boundaries of organic synthesis, laying the foundation for the creation of more novel and useful organic compounds.
To sum up, (4-nitrophenyl) benzenesulfonate plays an indispensable role in many fields and is of great significance to promoting the progress and development of science and technology.
What is the synthesis method of (4-Nitrophenyl) Benzenesulfonate?
The synthesis of (4-nitrophenyl) benzenesulfonate is a key issue in the field of organic synthesis. To make this substance, many paths can be followed.
First, benzenesulfonic acid and 4-nitrophenol are used as raw materials under suitable reaction conditions and obtained by esterification reaction. In this process, the catalyst needs to be carefully selected. Commonly used ones are concentrated sulfuric acid, which can effectively catalyze esterification reaction, but it is also highly corrosive, and special attention must be paid to safety during operation. Isothermal catalysts for p-toluenesulfonic acid can also be used, which have good catalytic activity and weak corrosiveness. During the reaction, the reaction temperature and time need to be precisely regulated. If the temperature is too low, the reaction rate is slow; if the temperature is too high, it may cause side reactions to breed. Generally speaking, the reaction temperature should be maintained within a certain range, and the reaction can be achieved after a certain period of time.
Second, the benzene ring can be modified first. For example, the sulfonic acid group is introduced into the benzene ring first, and then the nitro group is introduced through the nitrification reaction, and finally reacts with phenolic compounds to form a sulfonate. This path step is slightly complicated, but the reaction check point can be precisely controlled to obtain a higher purity product. In the nitrification reaction step, the mixed acid of nitric acid and sulfuric acid is a common reagent, and the reaction temperature should be strictly controlled to prevent excessive nitrification.
Third, phase transfer catalysis can also be used. In this method, the phase transfer catalyst can promote the transfer of the reactants between the two phases and accelerate the reaction process. The selection of suitable phase transfer catalysts, such as quaternary ammonium salts, can effectively improve the reaction efficiency and yield. The solvent selection of the reaction system is also very important, and it is necessary to consider the solubility of the reactants and catalysts and the effect on the reaction.
There are many methods for synthesizing (4-nitrophenyl) benzenesulfonate, each with its own advantages and disadvantages. Experimenters need to carefully choose the appropriate synthesis method according to their actual needs, such as product purity, yield requirements, and experimental conditions, in order to achieve the desired synthesis effect.
What are the precautions for the use of (4-Nitrophenyl) Benzenesulfonate?
(4-Nitrophenyl) benzenesulfonate, when using, there are a number of things to pay attention to, must keep in mind.
First, this material has a certain chemical activity. Its structure contains nitro and benzenesulfonate groups, both of which can participate in many chemical reactions. Therefore, when storing and using, be sure to beware of contact with active reagents, such as strong reducing agents, strong bases and the like. In case of strong reducing agents, nitro groups may be reduced, causing major changes in the structure and properties of the substance; in case of strong bases, benzenesulfonate groups or hydrolysis, the original substance will also fail, and even dangerous side reactions will occur.
Second, safety protection must not be ignored. (4-nitrophenyl) benzenesulfonate may be toxic and irritating. When operating, wear suitable protective clothing, gloves and goggles to avoid contact with the skin and eyes. If you come into contact accidentally, you should immediately rinse with plenty of water and seek medical treatment according to the specific situation. Operate in a well-ventilated place to prevent inhalation of its volatile aerosols. If inhaled, it may cause respiratory discomfort or even more serious health problems.
Third, it is essential to accurately control the reaction conditions. Temperature, reaction time and the proportion of reactants all have a great impact on the reaction results. If the temperature is too high, or the reaction is out of control, causing an increase in side reactions; if the temperature is too low, the reaction rate will be slow and take too long. The reaction time also needs to be accurately grasped. If it is too short, the reaction will be incomplete, too long or the product will decompose. The proportion of reactants is not appropriate, and it is difficult to achieve the expected reaction effect, or generate unnecessary by-products.
Fourth, the storage environment should also be paid attention to. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Humid environment may cause it to hydrolyze, high temperature may accelerate its decomposition and deterioration, so that the properties of the substance will decline and affect the use.
All these are the things that should be paid attention to when using (4-nitrophenyl) benzenesulfonate. Do not slack off to ensure the safety of operation and the smooth operation of experiments or production.
What is the approximate market price of (4-Nitrophenyl) Benzenesulfonate?
I don't know what the market price of (4-nitrophenyl) benzenesulfonate is. The price of various things in the market often changes due to many reasons, such as the state of supply and demand, manufacturing costs, quality, place of trade, season circulation, etc.
If the demand for this thing is wide, but the output is small, and the supply is not enough, the price will increase; on the contrary, if the output is abundant, but the demand is few, the price will exceed the demand. Its manufacturing cost is also the key. The price of raw materials is high, and the manufacturing process is complicated. The cost will increase, and the price will also rise. Quality also affects its price. Those with excellent quality often have higher prices than those with ordinary quality.
The trading places are different, and the prices are also different. In prosperous cities or places with convenient transportation, the prices may vary from other places due to smooth logistics and active markets. Seasonal circulation, or due to the seasonality of raw material output and the seasonality of market demand, the price fluctuates.
To know the exact market price of (4-nitrophenyl) benzenesulfonate, you should consult merchants, distributors in the chemical raw material market, or check the chemical product price information platform to get an accurate price. And its price changes rapidly, and the real-time price needs to be determined by careful investigation now.