What are the main uses of 4-Oxo-1, 4-Dihydropyridine-3-Sulfonic Acid?
4-Oxo-1,4-dihydropyridine-3-sulfonic acid has a wide range of uses. In the field of medicine, it is an important organic synthesis intermediate, often used as a key structural unit of many drugs, and plays a prominent role in the synthesis of cardiovascular drugs. For example, it can participate in the preparation of drugs with the effect of regulating blood pressure, helping to maintain the stability of human blood pressure. Its molecular structure characteristics make it unique in drug design and development, and it can be chemically modified to optimize drug activity and selectivity.
In the chemical industry, it plays a role in dye synthesis. Due to its specific functional groups, it can be used as a raw material for the synthesis of special structural dyes, endowing the dyes with unique properties such as light and thermal stability, so that they have excellent performance in fabric dyeing and ink manufacturing.
In the field of scientific research and exploration, as an important object to study the properties and reaction mechanisms of pyridine compounds, it helps researchers to deeply understand the chemical behavior of such compounds. Through the analysis of their reaction paths and product structures, it provides theoretical support and practical experience for the development of organic synthesis chemistry, promotes the birth of new synthesis methods and strategies, and lays the foundation for the creation of more functional materials and active substances.
What are the physical properties of 4-Oxo-1, 4-Dihydropyridine-3-Sulfonic Acid?
4-Oxo-1,4-dihydropyridine-3-sulfonic acid, this is a rather unique chemical substance. Its physical properties contain many interesting things.
Looking at its shape, under room temperature and pressure, it is mostly in the form of solid powder, which is easy to store and transport. Its color is often white to off-white, showing a pure state.
When it comes to solubility, it shows a certain solubility in water. This property is closely related to the sulfonic acid group in its molecular structure. The hydrophilic sulfonic acid group promotes the substance to interact with water molecules and dissolve in water to a certain extent. However, in organic solvents, such as common ethanol, ether, etc., the solubility is not good. This difference is due to the different degree of matching between the molecular polarity and the polarity of the organic solvent.
Its melting point is also one of the important physical properties. After measurement, it has a specific melting point value. This value provides an important basis for the identification and purification of the substance. During the heating process, when the melting point is reached, the substance changes from a solid to a liquid state. This transition process strictly follows the specific temperature conditions, which is of great significance for the study of its thermal stability.
In addition, the density of the substance also has a specific value. Although the density value seems ordinary, it plays a key role in many practical application scenarios. For example, when mixing and separation are involved in the reaction system, the density factor cannot be ignored.
In summary, the physical properties of 4-oxo-1,4-dihydropyridine-3-sulfonic acids are related to each other in terms of morphology, solubility, melting point and density, which together constitute their unique physical properties and lay the foundation for their application in chemical research and related fields.
What is the chemical synthesis method of 4-Oxo-1,4-Dihydropyridine-3-Sulfonic Acid?
To prepare 4-oxo-1,4-dihydropyridine-3-sulfonic acid, the method is as follows:
Usually a suitable pyridine derivative is used as the starting material. First take the pyridine with a specific substituent, and introduce the sulfonic acid group under the reaction conditions of delicate control. This process requires the selection of appropriate sulfation reagents, such as concentrated sulfuric acid and chlorosulfonic acid. During operation, make sure that the temperature of the reaction system and the proportion of the reactants are appropriate, so as to promote the precise connection of the sulfonic acid group to the third position of the pyridine ring.
Then, the fourth position of the pyridine ring is oxidized to convert it to a carbonyl group. A mild or strong oxidizing reagent can be used, depending on the specific substrate activity. If a suitable metal oxide or peroxide is treated in a specific solvent, the 4-position hydrogen atom is oxidized to a carbonyl group, and then 4-oxo-1,4-dihydropyridine-3-sulfonic acid is obtained.
After the reaction is completed, the product is often mixed in the impurities of the reaction system and must be carefully separated and purified. The method of recrystallization can be used to crystallize multiple times according to the solubility difference between the product and the impurities in different solvents to remove impurities. Column chromatography can also be used to select the appropriate stationary phase and mobile phase, so that the product and the impurities can be separated, and a pure 4-oxo-1,4-dihydropyridine-3-sulfonic acid can be obtained. In this synthesis path, each step is interconnected, and the operation details need to be carefully handled to obtain a product with satisfactory yield and purity.
What is the price range of 4-Oxo-1,4-Dihydropyridine-3-Sulfonic Acid in the market?
4-Oxo-1,4-dihydropyridine-3-sulfonic acid is difficult to determine in the market price range. Its price often changes due to many reasons, such as the quality of the product, the amount of demand, the difficulty of production, and the market conditions.
In the past, "Tiangong Kaiwu" said: "The price of all things in the world is impermanent, due to changes in supply and demand, and changes in technology." This is also true of 4-oxo-1,4-dihydropyridine-3-sulfonic acid. If its quality is good, and there are many people seeking it in the market, but it is difficult to produce, and complicated methods and rare materials are required, the price will be high. On the contrary, if the quality is average, the demand is weak, and the preparation is easy, the price may be low.
Looking at all kinds of chemical materials, their prices are often changing like the times. If you want to know the exact price range of 4-oxo-1,4-dihydropyridine-3-sulfonic acid, you should consult chemical material dealers, brokers, or check the price of its recent transactions on the chemical trading platform to get a more accurate number, and it is impossible to speculate.
What are the storage conditions for 4-Oxo-1,4-Dihydropyridine-3-Sulfonic Acid?
4-Oxo-1,4-dihydropyridine-3-sulfonic acid, this is a special chemical substance. Its storage conditions are crucial. According to the ancient principles of "Tiangong Kaiwu", the hiding of all things must be in line with its nature. This material may be sensitive to light and heat, and it is easy to react with other things. Therefore, the method of hiding should be cautious.
The first thing to do is to avoid direct light in a cool place. Those who are light can initiate chemical reactions and cause their qualitative changes. It is like exposing calligraphy and painting to the hot sun, and the color fades and destroys. The same is true for this acid. Under strong light, the structure may change easily and lose its original effect.
Second, a dry place is appropriate. Moisture is the enemy of many substances. In contact with water, this acid may dissolve or react, destroying its purity. For example, iron is rusted in a damp place. Therefore, it is necessary to choose a dry place to prevent moisture from invading.
Furthermore, it is sealed and stored. In the air, oxygen and various gases can mix with acids. Sealed, it is isolated from external disturbances and retains its essence. Such as Tibetan fine wine, the mouth of the jar is sealed, and the aroma exists.
To sum up, 4-oxo-1,4-dihydropyridine-3-sulfonic acid should be stored in a cool, dry and sealed environment to preserve its properties for a long time, so that it can be used without losing its chemical ability.