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What is the chemical structure of 4- (Phenylamino) Benzenesulfonate?
4 - (anilinyl) benzenesulfonate, its chemical structure is as follows. This compound is formed by linking a benzenesulfonate group to a benzene ring substituted by an aniline group.
The benzene ring is a six-membered carbon ring with a conjugated double bond structure, which is very stable. At position 4 of the benzene ring, a benzenesulfonate group is connected. In the benzenesulfonate group, the sulfur atom is connected to three oxygen atoms, two of which are connected to the sulfur by a double bond, and the other oxygen atom is negatively charged and can form a salt with a cation.
The aniline group is also based on the benzene ring. The lone pair electrons on the nitrogen atom are conjugated with the benzene ring, so that the aniline group The aniline group is attached to the benzene ring at position 4 through a nitrogen atom.
This chemical structure results in the unique physical and chemical properties of 4- (anilinyl) benzenesulfonate. The presence of the benzene ring gives it certain hydrophobicity, while the negative charge of benzenesulfonate gives it certain hydrophilicity and ionic properties. Due to the electronic effect of the aniline group and the benzenesulfonate group, the compound may have special uses in the fields of organic synthesis, pharmaceutical chemistry, etc. It can participate in many reactions as an intermediate, or exhibit specific biological activities based on its structural properties.
What are the physical properties of 4- (Phenylamino) Benzenesulfonate?
4- (phenylamino) benzenesulfonate, having a number of physical properties. Its shape or crystalline powder, usually white or off-white in appearance, this color is pure and pure, slightly shiny under light, just like the delicate jade chips. Its smell, almost no special smell, only a quiet place to smell, or a faint smell, but not enough to disturb.
When it comes to solubility, this substance has a certain solubility in water. When placed in an appropriate amount of water, it gradually dissolves to obtain a clear or slightly muddy liquid. When it dissolves, it may have a slight thermal effect, but it is not very significant. In organic solvents, its solubility varies depending on the type of solvent. Such as ethanol, it can also be dissolved, but the solubility is different from that of water.
Its melting point is also an important physical property. After determination, the melting point is in a specific temperature range, and this temperature limit is clear, which is one of the key markers for the identification of this substance. When heated to the vicinity of the melting point, the substance gradually melts, from the solid state to the liquid state, and the process is smooth and orderly.
Furthermore, the density of 4- (phenylamino) benzenesulfonate is also constant. Under normal temperature and pressure, the density is stable. This property is related to its distribution and behavior in various systems, and is of great significance in practical applications and research. The value of its density is the embodiment of the internal structure of matter and the forces between molecules, just like the unique imprint of matter, which cannot be ignored.
4- (Phenylamino) Benzenesulfonate is used in which fields
4- (phenylamino) benzenesulfonate is useful in various fields. In the field of medicine, it can be used as a pharmaceutical intermediate to assist in the synthesis of pharmaceuticals. Due to its specific chemical structure, it can participate in various reactions and create compounds with therapeutic effects to treat various diseases.
In the dye industry, this substance is also quite important. It can be a key raw material for the synthesis of dyes. With its structural properties, it can give dyes excellent color fastness and color. After chemical modification, dyes of different colors and properties can be obtained for dyeing fabrics, leather, etc., making their colors bright and lasting.
In the field of materials science, 4- (phenylamino) benzenesulfonate can be involved in the preparation of polymer materials. In addition, it can change the physical and chemical properties of the material, such as enhancing mechanical properties, thermal stability, etc. In the genus of plastics and rubber, it can be used as an additive to optimize its quality and expand the scope of application.
In addition, in some analytical chemistry experiments, it may be used as a reagent. With its reaction characteristics with specific substances, it can be used to detect and quantitatively analyze certain compounds, providing assistance for scientific research and quality control.
In industrial production, it may play a role in catalyst preparation, surfactant synthesis, etc., which is of positive significance for improving production efficiency and improving product quality. In short, 4 - (phenylamino) benzenesulfonate is indispensable in many fields, promoting the development and progress of various industries.
What are the preparation methods of 4- (Phenylamino) Benzenesulfonate
The preparation method of 4- (anilinyl) benzenesulfonate has been known for a long time, and there are many methods. Let me tell you one by one.
First, it can be prepared by reacting aniline with p-sulfobenzyl chloride under suitable conditions. Prepare the refined aniline first, which is active, and p-sulfobenzyl chloride needs to be pure and free of impurities. Place the two in a reactor, and choose a mild organic solvent, such as dichloromethane, to help it fully contact. Control the temperature in a moderate range, or add it slowly under an ice bath to prevent overreaction. During the process, it is necessary to constantly stir to mix the reactants evenly. After the reaction is completed, the crude product is obtained by extraction, washing, drying and other steps, and then purified by recrystallization to obtain a high purity 4- (anilinyl) benzenesulfonate.
Second, p-aminobenzenesulfonic acid reacts with halogenated benzene under the catalysis of a base. Take p-aminobenzenesulfonic acid, which is acidic, and first neutralize with the base to form a salt to increase its solubility. Halogenated benzene such as bromobenzene, chlorobenzene, etc., also need to be dried without moisture. Choose a suitable base, such as potassium carbonate, sodium carbonate, etc., in an organic solvent such as N, N-dimethylformamide, and heat and reflux. This reaction needs to pay attention to the activity of halogenated benzene. If the activity is not good After the reaction is completed, the target product is obtained by post-treatment, separation and purification.
Third, it is prepared by the coupling reaction of diazonium salts. The p-aminobenzenesulfonic acid is first prepared as a diazonium salt, and the p-aminobenzenesulfonic acid can be obtained by treating the p-aminobenzenesulfonic acid with sodium nitrite and inorganic acid at low temperature. Aniline derivatives are used as coupling components and react with the diazonium salt under appropriate pH conditions. This reaction requires strict temperature and pH requirements. If the temperature is too high or the pH is not appropriate, it is easy to cause side reactions to occur. After the reaction is completed, it is separated and refined to obtain 4- (aniline
These methods have their own advantages and disadvantages. According to actual needs, factors such as raw material availability, cost, yield and purity should be weighed, and an appropriate method should be selected to prepare 4- (anilinyl) benzenesulfonate.
What are the storage conditions for 4- (Phenylamino) Benzenesulfonate?
4- (phenylamino) benzenesulfonate is one of the chemical substances. Its storage conditions are essential to the properties and stability of this substance.
This substance should be placed in a cool and dry place. Cover a cool place to reduce its changes due to excessive temperature. If it is at high temperature, it may cause its chemical structure to change, its activity to change, or even decompose, damaging its quality and function. Dry places are also important because they are afraid of moisture. Moisture invades it, or causes it to deliquescent, chemically reacts with water, causing it to deteriorate.
and should be sealed and stored. The reason for sealing is to prevent it from contacting various components in the air, such as oxygen, carbon dioxide, etc. Oxygen or its oxidation, carbon dioxide or chemical reactions with it are not conducive to its preservation. It must also be kept away from fire and heat sources. Fire and heat can both stimulate its chemical reactions or cause danger, such as combustion and explosion.
As for the storage place, it should be selected in a well-ventilated place. With good ventilation, air circulation can remove harmful gases that may be generated, keep the storage environment safe, and also help maintain a suitable temperature and humidity. And it must be stored separately from oxidizing agents, acids, bases, etc. These substances, or with 4 - (phenylamino) benzenesulfonate, react violently, creating an unpredictable risk.
All these storage conditions are to protect the properties of 4- (phenylamino) benzene sulfonate, ensure its quality, and avoid danger. Those who use it must not ignore it.