Products

4-Toluenesulfonic Acid 2-Chloroethyl Ester

Lingxian Chemical

Specifications

HS Code

811424

Chemical Formula C9H11ClO3S
Molecular Weight 234.7
Appearance Typically a colorless to light - yellow liquid
Boiling Point Approximately 154 - 156 °C at 1.5 mmHg
Density Around 1.29 - 1.31 g/cm³
Solubility Soluble in many organic solvents like dichloromethane, ethyl acetate
Flash Point Caution: Flammable, flash point data varies but is relatively low
Pka Acidic compound, with pKa related to its sulfonic acid moiety
Reactivity Reactive towards nucleophiles due to the presence of the chloroethyl ester group
Packing & Storage
Packing 500g of 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester packaged in sealed, corrosion - resistant containers.
Storage 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture absorption and vapor leakage. Store it separately from oxidizing agents, bases, and reactive materials to avoid chemical reactions.
Shipping Shipping of 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester requires special handling. It should be packaged in sealed, corrosion - resistant containers and transported in accordance with hazardous chemical shipping regulations, ensuring safety during transit.
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4-Toluenesulfonic Acid 2-Chloroethyl Ester
General Information
Historical Development
The historical development of 4-toluenesulfonic acid 2-chloroethyl ester can be explored. In the past, organic chemistry flourished, and many wise men continued to study compounds. At that time, the exploration of various esters gradually expanded. 4-toluenesulfonic acid 2-chloroethyl ester was initially hidden in chemical mysteries.
and scientific evolution, researchers' eyes gradually focused on this. After repeated experiments and analysis, its characteristics and reaction rules were discovered. From the initial ignorance to the ability to precisely control its synthesis method, during which all wise men worked hard. Today, this compound is useful in various fields of industry and scientific research. The way to explore in the past is actually the basis for its use today.
Product Overview
Today there is a product called 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester. This is a key material in organic synthesis, and its properties are unique. Looking at it, it is often colorless to slightly yellow liquid with a special odor.
In terms of chemical properties, this product is quite active. It contains chloroethyl and p-toluenesulfonate ester groups, which cooperate and show unique effects in many chemical reactions. In the nucleophilic substitution reaction, chloroethyl is easily attacked by nucleophiles, achieving the replacement of groups, thereby constructing novel compound structures.
Furthermore, it is quite sensitive to reaction conditions. Temperature and solvent selection have a great impact on the reaction process and product formation. Only by precisely controlling the reaction conditions can the product be maximized in the field of organic synthesis, providing a solid foundation for the preparation of various fine chemicals, pharmaceutical intermediates, etc.
Physical & Chemical Properties
The physicochemical properties of 4-toluenesulfonic acid 2-chloroethyl ester are crucial. Looking at its properties, it is often a colorless to slightly yellow liquid, which can be clearly identified. Its boiling point is related to its gasification state. Under a specific pressure, the number of boiling points is also fixed, which is the main point for controlling its physical changes.
When it comes to solubility, it can show good miscibility in many organic solvents, such as ethanol and ether, which is the basis for its application in various reaction systems. In terms of chemical properties, because its structure contains chlorine atoms and sulfonate groups, it has active reactivity. In case of nucleophilic reagents, it is easy to react with nucleophilic substitution, and chlorine atoms can be replaced by other groups. And sulfonate groups can also participate in a variety of chemical reactions, and are widely used in the field of organic synthesis. They are of great importance to chemical researchers and contribute to the development and exploration of many synthetic paths.
Technical Specifications & Labeling
Today there are chemical products, named 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester. Its technical specifications and identification (commodity parameters) are the most critical. The technical specifications of this product must strictly abide by the order of the process. From the selection of raw materials, it is necessary to be pure and free of impurities; to the control of the reaction, the degree of temperature and pressure, the accuracy is no difference, so that the reaction is smooth, and the yield is constant.
In terms of identification (commodity parameters), the physical properties are detailed, such as color state, melting point, density geometry. Also remember chemical properties, activity and stability. Packaging labels, clear and visible, show warning words, storage methods, and handling. Only in this way can we ensure that this chemical product is safe and effective in all aspects of production, circulation and use.
Preparation Method
To prepare 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester, the raw materials and production process, reaction steps and catalytic mechanism are very important. First take p-toluenesulfonic acid as raw material, with an appropriate amount of chlorinated sulfoxide, the reaction between the two can activate the sulfonic acid group. In a flask, heat at controlled temperature to catalyze this reaction process, and chlorinated sulfoxide not only acts as a reactant, but also assists the reaction. During the reaction, pay attention to temperature changes to prevent side reactions from occurring.
After the sulfonic acid group is activated, slowly add chloroethanol and continue to stir to make the two fully contact the reaction. This step needs to control the dripping speed to avoid the reaction being too violent. During this period, a specific catalyst is used to catalyze the formation of ester bonds. After the reaction is completed, the product is purified by distillation, extraction and other steps, and the unreacted raw materials and by-products are removed to obtain a pure 4-Toluenesulfonic Acid 2-Chloroethyl Ester.
Chemical Reactions & Modifications
Today there is a chemical substance, named 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester. In the field of chemistry, its reaction and modification are crucial.
To observe the reaction, it is necessary to understand the influence of various conditions. Temperature, pressure, catalyst and other factors all affect the process and product of the reaction. If the temperature is not suitable, or the reaction is too slow or too aggressive, the product is impure.
As for modification, it is the important way to optimize its performance. Or by the introduction of groups, or by fine-tuning the structure, this substance has better performance in specific fields. For material synthesis, after modification, it may have stronger stability and solubility.
In order to make this chemical product play its ultimate function, it is indispensable to study its reaction and modification methods. Only by understanding this can we make good use of this product in chemical research and application and achieve ideal results.
Synonyms & Product Names
4 - Toluenesulfonic Acid 2 - Chloroethyl Ester, this product is quite crucial in my chemical research. Its nickname and trade name are also various.
Looking at the ancient books, it was once called "p-toluenesulfonic acid-2-chloroethyl ester". In the market, or "chloroethyl p-toluenesulfonic acid ester". Both are synonymous names and trade names. P-toluenesulfonic acid, originally a common acid, is combined with 2-chloroethanol to obtain the compound of this ester. Its unique properties, in the field of organic synthesis, are often important reagents or intermediates for reactions.
Its synonymous name and trade name help me express my meaning accurately and avoid confusion when communicating with the academic and industrial circles, and contribute greatly to the process of chemical research and production.
Safety & Operational Standards
Safety and operating specifications for 4-toluenesulfonic acid 2-chloroethyl ester
For 4-toluenesulfonic acid 2-chloroethyl ester, it is also an important substance involved in chemical preparation. To ensure the safety of its preparation and use, operating standards are the key.
When preparing, all matters must be observed. In the use of raw materials, it must be measured with accuracy. The ratio of 4-toluenesulfonic acid to 2-chloroethanol is related to the quality and quantity of the product, and the result may be completely different. And the storage of raw materials should not be underestimated. It should be placed in a cool and dry place, away from water and fire, and away from heat sources to prevent deterioration and accidents.
The operating environment is also a priority. The preparation site must be well ventilated to dissipate harmful gases and prevent their accumulation from endangering the human body. Furthermore, the control of temperature and pressure is related to the reaction process and product purity. It must be adjusted according to the needs of the reaction, with precise instruments, and must not be done at will.
The protection of the operator is of paramount importance. In front of protective clothing to prevent splashing and spraying the body. Masks and goggles are readily available to keep breathing and eyes safe. During operation, the movement should be steady and slow to avoid violent shaking that causes the reaction to go out of control.
After the reaction is completed, the product handling is also in accordance with regulations. Store in a special container, clearly marked, indicating its characteristics and hazards. When transporting, follow relevant regulations to ensure safety on the way.
All of these are the safety and operation specifications of 4-toluenesulfonic acid 2-chloroethyl ester. Practitioners should keep it in mind and act carefully to ensure that everything goes well and avoid disasters.
Application Area
4-Toluenesulfonic acid 2-chloroethyl ester is also an organic compound. Its application field is quite extensive. In the field of pharmaceutical synthesis, it is often used as a key intermediate. It can help form a variety of specific drugs, such as antibacterial and antiviral agents, and contribute to human health.
In the field of materials science, it also has wonderful uses. It can participate in the preparation of polymers, optimize material properties, such as improving their stability and plasticity. Make materials more practical in industrial manufacturing and daily necessities.
In organic synthesis reactions, it is an important reagent. With its unique chemical properties, it promotes various complex reactions, expands the boundaries of organic synthesis, and opens a new chapter in chemical research and industrial production. It is a widely used and indispensable chemical substance.
Research & Development
In recent times, chemical refinement has resulted in the emergence of new substances. In this case 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester, we have been researching this product for years.
At the beginning, the preparation method was still clumsy, the yield was quite low, and there were many impurities. However, our generation was unremitting, and we tried various paths, trying different materials, adjusting the temperature, time, and ratio of the reaction agent.
After several years of research, we gradually obtained exquisite methods. The newly made technique has greatly increased the yield and excellent purity. And this achievement can be used in various fields. In industry, or as a raw material, it can assist in the synthesis of other substances; in scientific research, it can be used as a reagent to explore the reaction mechanism.
Looking forward to the future, we should hold the heart of this research, and hope that this thing will make even greater progress, shining brightly in the fields of medicine, materials, etc., for the well-being of the world, promoting the progress of science and technology, and moving forward unremittingly, in order to reach a lofty realm.
Toxicity Research
I have heard all the sages talk about the nature of poisons. Today, I want to study the toxicity of 4-Toluenesulfonic Acid 2-Chloroethyl Ester in detail.
This substance has a unique structure, and the chloroethoxy group is connected to the p-toluenesulfonic acid base. Or think about it in the biochemical realm, and it is afraid of mutation. Chlorine atoms are highly active, or can nucleophilically attack biological macromolecules, such as proteins and nucleic acids. Sulfonate groups are also not good, and can cause alkylation changes.
In the way of experiments, try it with various creatures. Observe its characterization and observe its physiological changes. Or see cell aberrations, metabolic disorders, and organ damage. Push its mechanism, or because it hinders the activity of enzymes, disturbs the transmission of cell signals, and causes chaos in the order of life. Therefore, a detailed study of the toxicity of this substance has important significance in the safety of life and the protection of the environment, and cannot be ignored.
Future Prospects
I have tried this product 4 - Toluenesulfonic Acid 2 - Chloroethyl Ester. It is unique in nature and has a wide range of uses. In the field of chemical industry, it is expected to lead to a new path. Although the research is not deep at present, the future outlook is really promising. It may be able to create materials and have extraordinary achievements. With the help of new techniques, its quality may be refined again, and its effect may be improved again. At that time, in all kinds of industries, it can develop its growth and prosper. For the progress of future generations, adding strength and glory, this is my hope for its future.
Frequently Asked Questions
What are the main uses of 2-chloroethyl 4-toluenesulfonate?
4-Methylsulfoacetic acid 2-chloroethyl ester is an organic compound with a wide range of main uses.
In the field of pharmaceutical synthesis, this compound plays the role of a key intermediate. The preparation of many drugs requires it to participate in specific chemical reactions to build the key structure of drug molecules. For example, in the synthesis path of some antibacterial drugs, 4-methylsulfoacetic acid 2-chloroethyl ester can be introduced through a series of reactions to introduce specific functional groups, so that the drug has corresponding antibacterial activity, helping the drug to achieve the inhibition and killing effect of pathogens.
It also has important value in the creation of pesticides. It can be used as a raw material for the synthesis of new pesticides. By ingenious design and reaction, the pesticide is endowed with a unique chemical structure to achieve the purpose of controlling specific pests or diseases. For example, the synthesis of some high-efficiency and low-toxicity pesticides may be applied to this compound. Through its structural characteristics, the accuracy and effectiveness of pesticides on pests are enhanced, and the harm to the environment and non-target organisms is reduced.
In the study of organic synthetic chemistry, 4-methylsulfoacetic acid 2-chloroethyl ester is often used by chemists to explore novel reaction paths and methods due to its active chemical properties. With its special functional groups, it can carry out various substitution, addition and other reactions, providing new ideas and means for the development of organic synthetic chemistry, and promoting the continuous expansion and innovation of the field of organic synthesis.
What are the physicochemical properties of 4-toluenesulfonate 2-chloroethyl ester
2-Chloroethyl 4-methylpentanoate is an organic compound. Its physical and chemical properties are complex, and I will describe them in detail.
Looking at its properties, it is mostly a colorless to light yellow liquid at room temperature, with a clear texture and a specific smell. This smell is unique, or due to the interaction of atoms and groups in the molecular structure.
When it comes to solubility, this compound can be soluble in many organic solvents, such as ethanol, ether, acetone, etc. Due to the principle of "similar miscibility", its molecular structure has the characteristics of compatibility with organic solvents, resulting in miscibility between the two. However, its solubility in water is not good, because its molecular polarity is weak, and the force between water molecules is difficult to match the hydrogen bond between water molecules, so it is difficult to dissolve in water. The boiling point of 2-chloroethyl 4-methylpentanoate is also one of its important physicochemical properties. The boiling point of 2-chloroethyl 4-methylpentanoate is determined by the intermolecular forces, including van der Waals forces and dipole-dipole forces. The complexity of the relative mass and structure of molecules makes the intermolecular forces moderate, resulting in a specific boiling point range, which is crucial for the separation, purification and application of compounds. The melting point of
also cannot be ignored. The melting point of compounds is related to the regularity of molecular arrangement. The molecular structure of 2-chloroethyl 4-methylpentanoate affects its lattice energy, which in turn determines the melting point.
In terms of stability, it is still stable under normal conditions. When encountering high temperature, open flame or strong oxidizing agent, there is a potential safety hazard. High temperature can cause the thermal movement of molecules to intensify, and the chemical bond activity is enhanced; strong oxidizing agents can react with compounds and cause their structure to change.
Its density is also one of its characteristics. The density is affected by the molecular weight and the degree of intermolecular packing. The specific density value is an important consideration when storing, transporting and mixing with other substances of the compound.
In summary, the physical and chemical properties of 4-methylpentanoate 2-chloroethyl ester are diverse, and each property is related to each other, which affects its application in chemical, pharmaceutical and other fields. It is essential to clarify these properties for rational use and in-depth study of this compound.
What are the precautions for storing 4-toluenesulfonate 2-chloroethyl ester?
In the storage of 4-methylnaphthenic acid 2-chloroethyl ester, it is advisable to pay attention to the following things:
The first heavy storage environment. This environment exists in a good place where it is dry and dry. The degree of resistance is not high, so as to avoid its chemical properties. If it is high, the molecules or activity of the material will cause it to be changed and the effect will be reduced. The dry and dry conditions are essential, and the water is easy to lead to moisture decomposition, or the anti-corrosion of the product, and the composition of the rotten material. It is better to use dense containers to prevent the intrusion of air and moisture. Oxygen or oxidation of the material in the air to improve its chemical properties. Once the moisture enters, as mentioned above, it is easy to cause deliquescence and other diseases. If it falls on the soil, or dyes the product, it will affect its durability and effectiveness.
Re-storage period. It is necessary to comply with the storage period of the product, guarantee the effectiveness of the product during the storage period, or even harmful. The ingredients of the product will decompose and disappear over time. If it is used beyond the time limit, it will not only be effective during the harvest period, but also cause adverse reactions due to the melting of the product, which will endanger health.
In addition, the hidden product can be avoided by children. If this product is eaten by children, because children are young and tender, and their ability to tolerate the replacement of the product is weak, it will inevitably lead to heavy fruit and harm their health.
Therefore, when storing 4-methylnaphthenic acid 2-chloroethyl ester, we should pay close attention to the environment, container, expiration date, and user, so as to ensure the safety of the product.
What is the synthesis method of 4-toluenesulfonic acid 2-chloroethyl ester?
To prepare ethyl 4-methyl-2-pentenoate, the following method can be used.
First take an appropriate amount of isobutyraldehyde and malonic acid, put it in a reactor, use pyridine as a catalyst, heat it to carry out condensation reaction. The carbonyl activity of isobutyraldehyde is quite good. Under the catalysis of pyridine, the methylene active hydrogen of malonic acid undergoes nucleophilic addition to the carbonyl of isobutyraldehyde, and then dehydrates to generate 4-methyl-2-pentenoic acid. This reaction requires precise temperature control. If the temperature is too high, the side reactions will increase, and if it is too low, the reaction rate will be slow. Generally, it is maintained at a suitable temperature range to make the reaction proceed smoothly. After the reaction is completed, a relatively pure 4-methyl-2-pentenoic acid can be obtained by separation and purification.
Then, take the obtained 4-methyl-2-pentenoic acid, mix it with anhydrous ethanol, add an appropriate amount of concentrated sulfuric acid as a catalyst, and carry out the esterification reaction under heating and reflux conditions. Concentrated sulfuric acid can promote the esterification reaction forward, and attention should be paid to the removal of water in the system to avoid reverse reactions. After the reaction is completed, the reaction liquid is first cooled, and then the impurities are removed by separation, washing, drying and other steps. Finally, the distillation operation collects the fraction in a specific boiling point range to obtain 4-methyl-2-pentenoic acid ethyl ester.
During the operation, the dosage of each reactant needs to be accurately measured, and the reaction conditions such as temperature, time, catalyst dosage, etc. need to be strictly controlled, so as to ensure the smooth reaction and improve the yield and purity of the product.
What is the environmental impact of 2-chloroethyl 4-toluenesulfonate?
The impact of 4-methylimidazole 2-chloroethanol on the environment is related to all ecological things and cannot be ignored.
Fu 4-methylimidazole, this substance is widely used in the chemical industry and other industries. It enters the environment, or is discharged through wastewater and leaks of materials. If it flows in water bodies, aquatic organisms bear the brunt. Exposure of fish to this substance may cause physiological disorders, diseases in gills, livers and other organs, stunted growth and development, and reduced fertility. And this substance is difficult to degrade in water bodies, or persists in sediment for a long time, accumulating over the years, which is a deeper disaster.
As for 2-chloroethanol, it is also an environmental concern. It is toxic and irritating. If it escapes into the atmosphere and people are in it, it will damage the respiratory system, cause coughing, asthma, and even damage the lungs. If it falls on the soil, it will change the physical and chemical properties of the soil, inhibit the activity of soil microorganisms, hinder the growth of plant roots, and trap the vitality of vegetation. And it can be enriched through the food chain, from tiny organisms to large organisms, and the toxicity accumulates step by step, eventually endangering human health.
Both can migrate and transform in the environment, react with other substances, generate new pollutants, and make environmental problems more complicated. Although it has the power of natural purification, the rapid development of industry and the increase in emissions make it difficult for nature to counteract its harm. It is urgent to control sources and reduce emissions, develop green processes, reduce their impact on the environment, protect ecological safety, and ensure the harmony of all things.