4-Toluenesulfonic Acid

Lingxian Chemical

Specifications

HS Code	803783
Name	4-Toluenesulfonic acid
Chemical Formula	C7H8O3S
Molar Mass	172.202 g/mol
Appearance	Colorless to white solid
Odor	Typical sulfonic acid odor
Solubility In Water	Soluble
Melting Point	103 - 105 °C
Boiling Point	Decomposes
Acidity	Strong acid
Pka	-2.8
Density	1.24 g/cm³ (anhydrous)
Cas Number	104-15-4

Packing & Storage

Packing	500g of 4 - Toluenesulfonic Acid packaged in a sealed plastic - lined bag.
Storage	4 - Toluenesulfonic acid should be stored in a cool, dry, well - ventilated area. Keep it away from heat, ignition sources, and incompatible substances like strong oxidizers and bases. Store in tightly - sealed containers to prevent moisture absorption, which could affect its properties. It's best stored separately in a dedicated chemical storage area for safety.
Shipping	4 - Toluenesulfonic Acid is shipped in tightly - sealed containers, often drums or barrels. Due to its corrosive nature, it's handled with care during transit, following strict regulations to prevent spills and ensure safe transportation.

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General Information

Historical Development

4 - Toluenesulfonic Acid is also a sulfonic acid. Its origin can be traced back to the beginning of the chemical industry. At that time, various sages were committed to the research of new substances, and this acid gradually entered the field of vision. Early preparation, the process was not good, and the yield was quite low. However, the predecessors made unremitting efforts to study ways to improve it. With the passage of time, the technology has become more and more exquisite, and its output has also increased year by year. In the field of industry, 4 - Toluenesulfonic Acid has become more and more widely used. It is an important agent in organic synthesis, and the catalytic reaction depends a lot. From ancient times to the present, through the study of countless craftsmen, its position in the chemical industry has become more and more stable, with far-reaching influence, and it will also bloom brighter in the future.

Product Overview

4-Toluenesulfonic acid is also an organic compound. Its color is often white crystalline and has a unique smell. This substance is quite useful in the field of organic synthesis. Its properties are both acidic and can be used as a catalyst. In the esterification reaction, it can promote the reaction to accelerate and increase its efficiency. It also shows significant effectiveness in various reactions such as etherification and dehydration. When industrially prepared, toluene is mostly used as a base and obtained by sulfonation. The preparation process requires strict control of the reaction conditions, such as temperature, the proportion of reactants, etc., to ensure the purity and quality of the product. has a wide range of applications and is indispensable in the pharmaceutical, dye and fragrance industries. It can assist in the synthesis of various fine chemicals and make significant contributions to industrial production and scientific research.

Physical & Chemical Properties

4-Toluenesulfonic acid is one of the most important examples of organic compounds. Its physical properties are mostly white crystalline at room temperature, with a certain luster, and has a specific smell. It is easily soluble in solvents such as water and alcohols, and this solubility lays the foundation for its effectiveness in many reactions. When it comes to chemical properties, 4-toluenesulfonic acid is significantly acidic and often acts as a catalyst in organic synthesis reactions. It can catalyze esterification reactions, accelerate the synthesis of organic acids and alcohols, and promote the formation of esters. It can also play a role in some dehydration reactions, promoting the process of intramolecular or intermolecular dehydration. Its chemical activity is derived from the electronic effect of methyl groups on the benzene ring and the strong acidity of the sulfonic acid group. The synergy between the two gives this compound its unique chemical behavior, which is widely used in chemical, pharmaceutical and other fields.

Technical Specifications & Labeling

4-Toluenesulfonic acid is a commonly used agent in the chemical industry. Its process specifications and identification (product parameters) are very important. Looking at its process, it needs to be prepared in a clean and suitable environment. The raw materials must be selected with precision, and the ratio must be accurate. During the reaction, the temperature and speed are controlled, and the operation is rigorous to prevent side reactions. As for the logo, the name "4-toluenesulfonic acid" is clearly engraved on the product packaging, with a chemical formula. Indicate the content, mostly in exact percentages. Indicate the properties, such as white crystals. And warn its corrosiveness, with relevant icons. In this way, the process specifications are rigorous, and the identification is clear and accurate, so as to ensure product quality and user safety.

Preparation Method

4-Toluenesulfonic acid is also an organic compound. The method of preparation is related to the raw materials, production process, reaction steps and catalytic mechanism. Its raw materials are often based on toluene and sulfuric acid. Toluene is the initial substance, and sulfuric acid is the important agent for reaction promotion. In the production process, toluene and sulfuric acid are mixed in an appropriate ratio and reacted at a specific temperature and pressure. The reaction steps are as follows: When toluene encounters sulfuric acid, it becomes an intermediate. After a series of changes such as molecular rearrangement, 4-toluenesulfonic acid is finally obtained. In the catalytic mechanism, sulfuric acid is used as a catalyst to reduce the activation energy of the reaction and increase the reaction rate. In this way, through rigorous temperature control, pressure regulation and monitoring of the reaction process, the product of 4-toluenesulfonic acid can be obtained for the needs of various chemical fields.

Chemical Reactions & Modifications

4-Toluenesulfonic acid is also an organic compound. It is often used as a catalyst in various chemical reactions. Looking at the reaction, the reaction rate can be increased rapidly, just like a boat walking on water, with the wind helping. However, its properties can also be investigated. In case of high temperature, or contact with specific substances, it may appear unstable. If you want to make good use of it, you must study its reaction mechanism in detail to optimize it. Looking at past experiments, although some results have been achieved, there is still room for improvement. If you want to change its performance, you can start from its structure. Or increase or decrease the group, or adjust its spatial configuration, observe its changes in the reaction. With time and careful study, it will be able to play a better role in chemical reactions and contribute to all things chemical.

Synonyms & Product Names

4-Toluenesulfonic acid, also known as p-toluenesulfonic acid. It has a wide range of uses in the field of chemical industry. In the process of organic synthesis, it is often used as a catalyst to help many reactions proceed smoothly. Its aliases and trade names, although different, actually refer to the same. Looking back at the past, chemical names often varied depending on regions and habits, but their essence was the same. Nowadays in industrial production and academic research, although the names may be different, they all know that they refer to 4-toluenesulfonic acid. The names of chemical substances, such as personal names, may vary, but their properties and qualities remain constant. Therefore, when scholars understand the wonders of their synonymous names, they can obtain the true meaning of chemical research and use it freely in the chemical industry without confusion.

Safety & Operational Standards

4-Toluenesulfonic acid safety and operation specifications 4-Toluenesulfonic acid is a commonly used reagent in the chemical industry. When preparing, storing and using it, it is necessary to abide by safety and operation regulations to prevent accidents and ensure the safety of personnel and the environment. When preparing, the ratio of raw materials should be accurate, and the reaction conditions should be strictly controlled. If the temperature is too high, the reaction will be too fast, or the risk of flushing will be caused; if it is too low, the reaction will be slow and the yield will be reduced. Stirring should not be ignored, which can promote the uniform mixing of materials and make the reaction smooth. And the airtightness of the reaction device should be good to prevent the escape of harmful gases. Storage regulations are crucial. 4-Toluenesulfonic acid should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources, and avoid direct sunlight. Because of its corrosive nature, it should not be mixed with alkalis, oxidizers, etc. to prevent violent reactions. Packaging should also be tight to prevent leakage. When using, the operator must wear appropriate protective equipment, such as acid and alkali resistant gloves, protective glasses, protective clothing, etc. If it accidentally touches the skin, it should be rinsed with a lot of water immediately, and then seek medical treatment. If it splashes into the eyes, it is necessary to race against time to rinse with flowing water or normal saline, and quickly send it to the hospital for first aid. When taking it, the action should be stable to avoid spillage. After use, the remaining medicines should be properly disposed of according to regulations and should not be discarded at will. In the experimental or production site, emergency facilities must be complete. Such as eye washers, spray devices, etc., should be checked regularly to ensure their normal operation. Ventilation equipment is also indispensable to remove volatile gas and reduce the concentration of harmful substances in the air. In short, although 4-toluenesulfonic acid is an important chemical, its safety and operation standards must not be slack. Only by strictly observing this regulation can everyone move forward steadily in the chemical industry without worry.

Application Area

4-Toluenesulfonic acid is an important chemical. It has a wide range of application fields and is often used as a catalyst in the field of organic synthesis. For example, when the esterification reaction is carried out, the addition of this agent can greatly increase the reaction rate and make the formation of ester products smoother. In the pharmaceutical industry, it also has its own influence. With its unique chemical properties, it helps the drug synthesis step and improves the purity and yield of the drug. And in the preparation of some fine chemical products, 4-toluenesulfonic acid can also play a key role, helping the reaction proceed in the expected direction and optimizing the product quality. It can be seen that 4-toluenesulfonic acid has an indispensable position in many application fields and has a far-reaching impact on industrial production and scientific research.

Research & Development

In recent years, I have had some experience in the research of 4 - Toluenesulfonic Acid. This compound has a wide range of uses and has made great achievements in the field of organic synthesis. I began to study it, first exploring its properties, deconstructing it, and observing its reactions in different environments. I also tried various methods to make it, seeking its superiority, hoping to improve the yield and reduce consumption. The study of its catalytic ability shows that it is effective, can promote all kinds of reactions, and the conditions are easy. Looking at its development, the prospect is bright. With the advance of science and technology, its application in new fields will be gradually expanded. We should do our best to study its principles and explore its uses widely, hoping to achieve its more prosperous development, add bricks and tiles to the chemical industry, and benefit the world.

Toxicity Research

Taste the industry of chemical industry, and explore the nature of things in depth. Today, it is particularly important to study the toxicity of 4-Toluenesulfonic Acid. Although this substance has its uses in various places in the chemical industry, the study of toxicity cannot be ignored. Looking at its properties, or touching it, or smelling it, can cause discomfort to the body. If the skin touches it, it may cause redness and swelling; if the mouth and nose smell it, it may disturb the smooth breathing. The investigation of toxicity is related to the well-being of craftsmen and the safety of the environment. Therefore, it is necessary to carefully observe its nature and implement protective measures to keep workers away from its harm, and the environment will not be contaminated by it. In this way, the karmic and safe state of the chemical industry can be achieved.

Future Prospects

Husband 4 - Toluenesulfonic Acid, the thing that transforms the body is also the thing that transforms the body. Today, there are still many things to look forward to. Its unique nature, in the process of multiplication and reaction, often depends on the importance of catalysis, the rate of increase, the rate of increase, and the effect. In the future, science and technology are changing, and this acid may be beneficial for more precise chemical synthesis. The research of new materials, its help, may be able to create things beyond today, to meet the needs of each company. The field of development, or because of it, may gain new insights, and save the world. And to ensure the prosperity of the mind, the way to study its color method and efficient use will be necessary. Hoping to reduce its energy consumption, reduce its pollution, and make the chemical engineering work better. In this way, the possibility of the 4-Toluenesulfonic Acid's future and the limit of its charging is very exciting.

Frequently Asked Questions

What are the main uses of 4-Toluenesulfonic Acid?

4-Toluenesulfonic acid has many main uses. First, in the field of organic synthesis, it is often used as a catalyst. Because of its acidic nature, it can promote the progress of many organic reactions, such as esterification reactions. Alcohols and carboxylic acids can be catalyzed by it to form esters more easily, which is quite critical in the synthesis of fragrances, drugs, etc. Another example is the formation reaction of acetals and ketals. 4-Toluenesulfonic acid can help the reaction to occur efficiently and provide convenience for the construction of organic compounds. Second, it is also useful in the preparation of some polymers. It can regulate the rate and process of polymerization reactions to achieve specific structures and properties of polymers. For example, in the synthesis of specific polyesters, it can affect the growth and cross-linking of molecular chains, which in turn affects the physical and chemical properties of the products. Third, in industrial production, it is also used in some cleaning, rust prevention and other products. Because of its acidity, it can moderately dissolve certain metal oxides or dirt, play a role in cleaning the metal surface, and can inhibit metal rust to a certain extent, ensuring the good condition of industrial equipment and metal products. Fourth, in scientific research experiments, as a common reagent, it is used to adjust the acidity of the reaction system, providing necessary conditions for the study of specific chemical reaction mechanisms, the exploration of new synthesis methods, etc., to help researchers in-depth understanding of the laws of chemical change, and promote the development of chemical disciplines.

What are the Physical Properties of 4-Toluenesulfonic Acid?

4-Toluenesulfonic acid is a common acid in organic compounds. Its physical properties can be described in many ways. Under normal temperature, it often appears as a white crystalline solid. When the quality is pure, the appearance is clean and the texture is fine, like fine sand, and the luster is soft. This substance has strong water absorption. When placed in the air, it easily absorbs water vapor and deliquescence, just like a sponge absorbs water. When it comes to odor, 4-toluenesulfonic acid emits a weak special smell. Although it is not pungent and intolerable, it can also be detected by those with a keen sense of smell. This smell is slightly similar to common organic sulfonic acids. Besides, its solubility is very high in water. Once it is integrated, it interacts with water molecules instantaneously to form a uniform solution, just like salt dissolves naturally in water. Not only that, but it can also show good solubility in many polar organic solvents, such as ethanol and acetone. This characteristic makes it in organic synthesis reactions, when used as a catalyst, it can fully contact with the reactants and play an efficient catalytic role. The melting point of 4-toluenesulfonic acid is about 103-105 ° C. When the temperature rises to this range, the originally solid crystal will gradually melt into a liquid state like ice and snow in the warm sun. This transformation is quite wonderful. Temperature control is crucial when it is used and stored. As for the boiling point, because it is easy to decompose at high temperature, the exact boiling point is rarely reported. However, during the organic synthesis operation, special attention should be paid to temperature control to prevent it from decomposing and losing its original chemical activity and function.

4-Toluenesulfonic Acid What to pay attention to when storing

4-Toluenesulfonic acid is a common compound in organic chemistry. When storing it, many matters must be paid attention to. First environment. Must choose a dry place. If it is humid, 4-toluenesulfonic acid is easy to absorb moisture. Because of its water absorption, it may change its properties after moisture absorption, which affects its quality and effectiveness. And the warehouse should be cool, the temperature is too high, or its chemical properties may change, and there is even a risk of decomposition. Second words packaging. The packaging used must be tightly sealed to prevent the intrusion of external moisture, air, etc. Glass containers or plastic containers lined with special materials are commonly used, but glass must be prevented from breaking and causing 4-toluenesulfonic acid to leak. Furthermore, it should not be co-stored with alkaline substances. 4-Toluenesulfonic acid is acidic, and when it encounters alkali, it will neutralize, which will not only damage itself, but also cause unexpected chemical reactions, which will cause safety risks. The oxidant should also be kept away. The mixture of 4-toluenesulfonic acid and the oxidant may trigger a violent reaction, causing dangerous situations such as combustion and explosion. In addition, the storage place should be well ventilated. If the ventilation is poor, once 4-toluenesulfonic acid has a small amount of volatilization, its gas will accumulate, which will not only endanger the health of warehousers, but also increase safety risks. At the same time, fireworks must be strictly prohibited in the storage area. Although 4-toluenesulfonic acid is not highly flammable, it may burn under certain conditions. In case of open flames or hot topics, the danger will be immediate. In summary, proper storage of 4-toluenesulfonic acid is crucial in many fields such as chemical experiments and industrial production, and must not be taken lightly.

What are the safety risks during the use of Toluenesulfonic Acid?

4-Toluenesulfonic acid is a commonly used reagent in organic chemistry. Its use poses many safety risks and needs to be treated with caution. First, it is corrosive. 4-Toluenesulfonic acid has a strong corrosive effect on the skin, eyes and respiratory mucosa. If accidentally touched the skin, it can cause skin burns, redness, pain, blisters and other symptoms; if splashed into the eyes, it can cause serious damage to the eyes, and even cause blindness; inhalation of its volatile gas can also irritate the respiratory tract, causing cough, asthma, breathing difficulties, etc. Second, flammable. Although it is not flammable by itself, when heated or in contact with an open flame, it will decompose and release flammable and toxic gases, which can easily cause fires or even explosions when exposed to fire sources. Third, toxicity. 4 - Toluenesulfonic acid and its decomposition products can enter the human body through the respiratory tract, skin and digestive tract, causing toxicity to the human body. Long-term exposure or inhalation of its vapor may damage the functions of important organs such as the liver and kidneys, and affect the normal physiological metabolism of the human body. Fourth, reactive activity. 4 - Toluenesulfonic acid, as a strong acidic catalyst, is highly active in some chemical reactions. If the reaction conditions are not properly controlled, such as temperature and concentration, it is easy to cause violent reactions, resulting in dangerous conditions such as flushing and spraying, endangering the safety of personnel and the environment. Therefore, when using 4-toluenesulfonic acid, it is necessary to strictly follow the safety operating procedures and wear protective equipment such as protective glasses, gloves, protective clothing and gas masks. The operation should be carried out in a well-ventilated environment, away from fire and heat sources. Store properly to prevent leakage. In the event of a leak or contact accident, take immediate emergency measures and seek medical attention in a timely manner.

What are the Preparation Methods of 4-Toluenesulfonic Acid

4-Toluenesulfonic acid (4-Toluenesulfonic Acid) is prepared by the following methods. One is the toluene sulfonation method. This is a classic method, using toluene as the raw material and sulfuric acid as the sulfonating agent. In a specific reaction vessel, toluene and sulfuric acid are mixed in a certain proportion, and at a suitable temperature, the two undergo a sulfonation reaction. During the reaction, the sulfonyl group of sulfuric acid (-SOH) replaces the hydrogen atom on the toluenesulfonic ring to generate 4-toluenesulfonic acid. This reaction requires precise temperature control. If the temperature is too low, the reaction rate will be slow, and if it is too high, side reactions will easily occur, resulting in impure products. Generally speaking, the reaction temperature is mostly controlled at about 100 degrees Celsius. After the reaction is completed, the pure 4-toluenesulfonic acid can be obtained through various steps such as cooling, separation and purification. The second is the reaction method between p-cresol and sulfuric acid. P-cresol is used as the starting material to interact with sulfuric acid. The hydrogen atom of the phenolic hydroxyl ortho or para-position of p-cresol is highly active, and it is easy to replace with the sulfuric group of sulfuric acid to generate 4-toluenesulfonic acid. This reaction condition is relatively mild and requires slightly less equipment. However, the cost of p-cresol raw materials may be high, which affects the wide application of this preparation method to a certain extent. During the reaction process, attention should also be paid to the control of reaction time and temperature to ensure the yield and purity of the product. The third is the reaction method of toluene and chlorosulfonic acid. With toluene and chlorosulfonic acid as reactants, the reaction between the two can quickly generate 4-toluenesulfonic acid. The sulfonation ability of chlorosulfonic acid is stronger than that of sulfuric acid, so the reaction rate is faster. However, chlorosulfonic acid is highly corrosive and irritating, and extra caution must be taken during operation, and the reaction will produce hydrogen chloride gas, which needs to be properly handled to prevent environmental pollution. After the reaction is completed, the target product 4-toluenesulfonic acid can be obtained through corresponding separation and refining operations.