Products

5-Chlorothiophene-2-Sulfonic Acid Tert-Butylamide

Lingxian Chemical

Specifications

HS Code

183507

Chemical Formula C8H12ClNO3S2
Molecular Weight 269.77
Appearance Solid (Typical description, actual may vary)
Solubility In Water Limited (General assumption for such organic compound)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone (General prediction)
Stability Stable under normal conditions (General prediction)
Packing & Storage
Packing 250g of 5 - Chlorothiophene - 2 - Sulfonic Acid Tert - Butylamide in sealed chemical - grade pouch.
Storage Store 5 - Chlorothiophene - 2 - Sulfonic Acid Tert - Butylamide in a cool, dry place, away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption and oxidation. Store separately from incompatible substances, such as strong acids, bases, and reactive chemicals, to avoid chemical reactions. Label the storage area clearly for easy identification and safety.
Shipping 5 - Chlorothiophene - 2 - Sulfonic Acid Tert - Butylamide is shipped in well - sealed, corrosion - resistant containers. Handling during transit follows strict chemical safety regulations to prevent leakage and ensure safe delivery.
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5-Chlorothiophene-2-Sulfonic Acid Tert-Butylamide
General Information
Historical Development
5-Chlorothiophene-2-sulfonic acid tert-butylamide, the beginning of this substance is really derived from the dedication of Zhu Xian to chemical exploration. In the past, Zhugong studied sulfur heterocyclic compounds and wanted their new changes. At the beginning, the basic thiophene structure was gradually modified. After many trials and errors, the chlorine atom was added to the fifth position of thiophene, and this change caused the properties of the compound to slightly change. Later, the sulfonic acid group was connected to the second position to add new energy. Finally, the tert-butylamide group was connected, so this 5-chlorothiophene-2-sulfonic acid tert-butylamide was formed. The process is the condensation of the wisdom and sweat of countless chemists. From the simple conception to the realization of this compound, every step has been the imprint of the chemical exploration journey, and a new path has been opened for subsequent chemical research and application.
Product Overview
5-Chlorothiophene-2-sulfonic acid tert-butylamide is an important substance in chemical research. It is an organic compound with a unique chemical structure. The presence of chlorine atoms and sulfonic acid tert-butylamide groups on the thiophene ring endows it with specific chemical properties.
This compound has great potential in the field of organic synthesis and can be used as a key intermediate. Due to its special structure, it can participate in a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc. In drug development, it may be used to construct molecular structures with specific activities, laying the foundation for the creation of new drugs. In the field of materials science, it may be chemically modified to prepare functional materials with special properties. In-depth study of it is expected to expand the boundaries of chemical science and generate more innovative results.
Physical & Chemical Properties
5-Chlorothiophene-2-sulfonate tert-butylamide, the physical and chemical properties of this substance are related to many aspects. Its appearance may be in a specific form, or as a powder, or as a crystal, which can only be determined by careful observation. In terms of solubility, it varies in different solvents, and the degree of solubility in water and organic solvents varies. This property affects its dispersion in various reaction systems and the degree of participation in the reaction.
Furthermore, its stability cannot be ignored. Under different temperature, humidity and light conditions, the stability changes. High temperature or high humidity environment may accelerate its decomposition or deterioration. In terms of chemical activity, the functional groups it contains determine the possibility of reacting with other substances. Chlorine atom and sulfonic acid tert-butylamide group can both initiate specific chemical reactions, providing the possibility for the synthesis of new compounds. The study of its physical and chemical properties is the key to in-depth understanding and rational application of this substance.
Technical Specifications & Labeling
5-Chlorothiophene-2-sulfonate tert-butylamide technical specifications and labels (product parameters)
5-chlorothiophene-2-sulfonate tert-butylamide, the technical specifications need to identify the purity of the material, the raw materials used must be carefully selected, and the impurity content must be strictly controlled at a very low degree. During synthesis, the reaction temperature, duration and reactant ratio are all key, and precise control can lead to high-quality products.
In terms of labeling, on the product packaging, the name "5-chlorothiophene-2-sulfonate tert-butylamide" should be clearly engraved, and the product parameters should be detailed, such as molecular formula, molecular weight, purity value, etc. At the same time, warning labels are also indispensable to inform the relevant hazards and protection methods, so that the contact person knows the risk and handles it with caution. In this way, it is necessary to meet the technical specifications and labels to ensure product quality and safety.
Preparation Method
Formulation method of 5-chlorothiophene-2-sulfonic acid tert-butylamide (raw materials and production process, reaction steps, catalytic mechanism)
To prepare 5-chlorothiophene-2-sulfonic acid tert-butylamide, first take an appropriate amount of 5-chlorothiophene as the initial raw material, mix it with sulfur-containing reagents in a specific ratio, and heat it to promote the reaction. This is the key starting step. During the reaction, the temperature and duration are precisely controlled to ensure sufficient reaction. After the initial reaction is completed, a mixed solution containing the target substance is obtained.
Then, the mixed solution is separated and purified by a specific process. Appropriate solvent extraction is used to remove impurities by filtration, distillation, etc., to obtain a purer intermediate product.
Then, the intermediate product reacts with tert-butylamine under catalytic conditions. Select an appropriate catalyst, control the reaction environment, accelerate the reaction process, and improve the yield. After a series of reactions and treatments, 5-chlorothiophene-2-sulfonate tert-butylamide is finally obtained. The whole process, the selection of raw materials, the control of reaction conditions and the connection of each step are the key to the preparation, which is related to the quality and yield of the product.
Chemical Reactions & Modifications
5-Chlorothiophene-2-tert-butylamide sulfonate is also an organic compound. In the field of chemistry, it is our research priority to explore its reaction and modification.
The reaction of this compound may involve nucleophilic substitution or the change of electron clouds. The structure of its sulfonic acid tert-butylamide can take different reaction paths due to external conditions, such as temperature and catalysts. Or in contact with nucleophiles, the sulfonic acid group leaves, and a new bond is formed.
As for modification, it is designed to optimize its properties. The introduction of groups can be used to change its solubility and stability. For example, the introduction of a specific functional group may greatly increase its solubility in a specific solvent, and its stability in a specific environment exceeds the previous.
Our chemical researchers should carefully study the reaction and modification of this compound to expand the boundaries of chemical applications and add new power to various fields, such as medicine and materials.
Synonyms & Product Names
5-Chlorothiophene-2-sulfonate tert-butylamide, this substance has attracted much attention in today's chemical research. Its synonyms and trade names are the focus of our investigation.
In the past, there was no current standard for naming chemical substances. In different places and different research groups, the same substance is often called by different names. This 5-chlorothiophene-2-sulfonate tert-butylamide, or due to structural characteristics, some people use its chlorine, thiophene, sulfonic acid and tert-butylamide parts as aliases; or according to the preparation method and use, it has different names.
However, the choice of a trade name is often related to commercial considerations. Businesses want their names to be unique and easy to remember, so that they can be different from others and attract customers. Therefore, the same 5-chlorothiophene-2-sulfonate tert-butylamide has also won the names of various commodities when it is in circulation in the market.
Today, it is of great significance to clarify its synonyms and trade names in chemical research, industrial production and trade exchanges. It can avoid confusion caused by complicated appellations and promote smooth communication and collaboration among all parties.
Safety & Operational Standards
Code for safety and operation of 5-chlorothiophene-2-tert-butylamide sulfonate
If 5-chlorothiophene-2-sulfonate tert-butylamide is chemically prepared, it is also necessary to ensure the smooth operation of the experiment, the safety of personnel, and safety and operation standards.
The preparation site should be well ventilated. Cover this compound or contain volatile components. If it accumulates in the room, it is easy to cause poisoning. Ventilation equipment can quickly discharge harmful gases and keep the indoor air fresh.
When handling this substance, protective equipment must be worn. Gloves need to be resistant to chemical corrosion, so as not to touch the skin with drugs and cause skin damage; goggles are also indispensable, so as to prevent splashing into the eyes and damage the eyesight.
The method of use should be used with caution. Use clean and accurate utensils, take according to the quantity, not more or less. If there is any spill, clean it up immediately to prevent pollution of the environment and endanger others.
During the reaction, it is essential to control the temperature and time. Different temperatures and durations have different products, and it is related to safety. Overheating may cause the reaction to go out of control and explode; short duration also affects the purity of the product.
When storing, choose a dry and cool place, away from fire and heat sources. Sealed and stored to prevent reaction with air and moisture, deterioration and failure, and avoid mixing with other chemicals, prevent interaction and unexpected changes.
Waste disposal should be carried out according to regulations. It should not be discarded at will, sorted and collected, and handled by professional institutions to protect the environment and avoid public hazards.
In short, the handling of 5-chlorothiophene-2-sulfonate tert-butylamide, in accordance with safety and operating standards, can save the danger, achieve the purpose of the experiment, and protect the safety of everyone.
Application Area
5-Chlorothiophene-2-sulfonic acid tert-butylamide is widely used in the field of chemical industry. In the field of pharmaceutical creation, it can be a key intermediate to help synthesize special and good drugs to cure various diseases. For example, a certain type of antibacterial agent, with its unique structure and drug-enhancing effect, expands the spectrum of antibacterial.
In the field of material research and development, it also has extraordinary functions. It can be added to polymer materials through specific reactions to improve their properties. It makes the material have excellent weather resistance and corrosion resistance, and shines brightly in outdoor facilities, chemical equipment and other materials.
And it is also indispensable in the preparation of pesticides. It can help to produce high-efficiency and low-toxicity pesticides, precisely eliminate pests, protect the growth of crops, and ensure the abundance of agricultural products. All of these demonstrate its important position in multiple application fields and contribute to the progress of chemical technology.
Research & Development
5-Chlorothiophene-2-sulfonate tert-butylamide, the research and development of this compound is very important in the field of chemical exploration in China. In the past, many studies focused on its synthesis path. At the beginning, the synthesis method was cumbersome and the yield was low. After repeated research, an optimized method has been found, which can effectively improve the yield.
The study of its properties has also made progress. After testing, the substance has unique solubility in specific solvents and good stability.
At the application level, it has been found to have great potential in the field of pharmaceutical intermediates. Although some achievements have been made, there are still challenges. In the future, when deepening research, optimizing the synthesis process, and expanding the scope of application, we hope to promote the research and development of this compound to a new level and add to the field of chemistry.
Toxicity Research
Taste the industry of chemical industry, and explore the properties of substances in detail. Now on 5 - Chlorothiophene - 2 - Sulfonic Acid Tert - Butylamide, the study of its toxicity is crucial.
Examine the ancient books in detail, and if you want to clarify its toxicity, you need to do more methods at the same time. Observe its chemical structure, containing chlorine, sulfur and other elements, or potentially toxic. However, it is difficult to determine the whole picture according to the structure.
Repeat to verify, select all kinds of creatures, and observe their effects on this substance. Observe its physiological characteristics and changes in behavior, and analyze the damage to the organs. If the tested organism shows signs of illness, such as slow movement and organ lesions, its toxicity can be proved.
It is also considered in the shadow of the environment, which is scattered outside, or harmful to water and soil life. Entering the water body will disturb the aquatic state; storing the soil will also endanger the safety of grass and trees.
In summary, the study of toxicity is not achieved overnight, and it must be carefully investigated to obtain the truth, so as to ensure the safety of all things and the peace of the environment.
Future Prospects
Fu 5-chlorothiophene-2-sulfonate tert-butylamide is also a new product of chemistry. Looking at its current state, it seems to have extraordinary quality. In the opinion of my researchers, its future development will definitely have great potential.
This product may be used in various manufacturing processes, such as the field of pharmaceutical synthesis, or it can add wings to the cure of diseases. Its unique structure and stable properties can be the cornerstone of innovative drugs.
It is also expected to emerge in the genus of materials science. It may be able to change the properties of materials and make them more suitable for high-tech needs.
Although it is not widely used today, looking at it in the long run, with time and good research, it will be able to expand its path, create a new situation, and shine in the future world, adding a touch of brilliance to the grand event of transformation.
Frequently Asked Questions
What are the chemical properties of tert-butylamide 5-chlorothiophene-2-sulfonate?
Good, what you are asking is about the chemical properties of trimethyl borate. Trimethyl borate is an organoboron compound, and its specific properties are worth exploring.
Trimethyl borate, at room temperature, is a colorless and transparent liquid with a pungent odor. Its boiling point is quite low, about 68-69 ° C. This property makes it easy to change from liquid to gaseous state under certain temperature conditions and evaporate in the surrounding environment. Its density is smaller than that of water, so if it encounters water, it can float on the surface of the water.
In terms of solubility, trimethyl borate is soluble in many organic solvents, such as ethanol, ether, etc. This is because its molecular structure can form a specific interaction with the molecules of organic solvents, so that it can be uniformly dispersed. However, its solubility in water is limited, and although it can react with water to a certain extent, it is difficult to dissolve in large quantities.
The chemical activity of trimethyl borate is also characterized. The boron atom in its molecule is electron-deficient, which makes it easy to accept electron pairs and exhibits Lewis acidity. When encountering nucleophiles, boron atoms can combine with the electron-rich parts of nucleophiles to initiate various chemical reactions. For example, it can be transesterified with compounds containing hydroxyl groups. This reaction is widely used in the field of organic synthesis and can be used to prepare other organic borate esters.
In addition, trimethyl borate poses a risk of combustion at high temperatures or in contact with open flames. Because it is an organic compound, it is flammable. When storing and using, be sure to pay attention to fire and explosion protection. Keep it in a cool and ventilated place, away from fire sources and oxidants.
In summary, trimethyl borate has important uses in many fields such as organic synthesis and materials science due to its unique physical and chemical properties. However, when using it, it is also necessary to be careful and follow the corresponding safety procedures.
In which fields is 5-chlorothiophene-2-sulfonate tert-butylamide used?
5-Alkanidine-2-sulfonate guanidourea is a special chemical substance that has applications in many fields and has unique effects.
In the field of medicine, this substance has shown important value. Because it has certain biological activity, it may be used as a key intermediate in drug synthesis. By ingenious modification and modification of its chemical structure, new drugs with specific pharmacological effects can be prepared, or can be used to treat certain diseases, such as specific inflammation or metabolic disorders and other related diseases.
In the field of agriculture, 5-alkanidine-2-sulfonate guanidourea also has applications. It may act as a plant growth regulator and affect the growth and development process of plants. For example, it can adjust the flowering and fruiting time of plants, improve the yield and quality of crops; it can also enhance the resistance of plants to pests and diseases, reduce the use of pesticides, and thus contribute to the development of green agriculture.
In the field of materials science, this substance can also play a role. Because of its special chemical properties, it can be used to prepare high-performance materials. For example, introducing it into polymer materials can improve the mechanical properties and thermal stability of materials, thereby expanding the application range of materials in high-end fields such as aerospace and electronic equipment.
In addition, in some aspects of industrial production, 5-alkamidine-2-sulfonate guanidourea may be used as a component of catalysts to accelerate the progress of specific chemical reactions, improve production efficiency, reduce production costs, and have positive significance for the optimization and improvement of industrial production. In short, this substance has certain application potential in many fields such as medicine, agriculture, materials science, and industrial production. With the continuous deepening of research, its application prospects may be broader.
What is the synthesis method of 5-chlorothiophene-2-sulfonate tert-butylamide?
To prepare fluoxetine hydrochloride for 5-hydroxytryptamine-2-receptor antagonist, the method is as follows:
First take p-chloronitrobenzene, and 3-chloro-1,2-propylene oxide in an appropriate solvent, add alkali catalysis, and heat up the reaction to obtain 1 - (3-chloro-2-hydroxypropyl) -4-chloronitrobenzene. This step requires temperature control and control to make the reaction sufficient. Next, 1 - (3 - chloro - 2 - hydroxypropyl) - 4 - chloronitrobenzene is reacted with dimethylamine. Under suitable conditions, the amine group replaces the chlorine atom to obtain 1 - (3 - dimethylamino - 2 - hydroxypropyl) - 4 - chloronitrobenzene. This reaction requires attention to the material ratio and reaction environment.
Then with a suitable reducing agent, such as iron powder and hydrochloric acid system, 1- (3-dimethylamino-2-hydroxypropyl) -4-chloronitrobenzene is reduced to convert the nitro group into an amino group to obtain 1- (3-dimethylamino-2-hydroxypropyl) -4-chloroaniline. Pay attention to the amount of reducing agent and the reaction process during operation.
Subsequently, 1- (3-dimethylamino-2-hydroxypropyl) -4-chloroaniline and 2-chlorobenzoic acid under the action of a condensing agent undergo a condensation reaction to form a key intermediate. This process requires strict reaction conditions and requires fine regulation.
Finally, the intermediate is reacted with hydrochloric acid through a salt-forming reaction to obtain fluoxetine hydrochloride. Pay attention to controlling the pH and crystallization conditions during salt formation to obtain a high-purity product.
Throughout the synthesis process, careful operation is required at each step of the reaction, and fine control of the reaction conditions can improve the yield and purity to obtain qualified fluoxetine hydrochloride.
What is the market prospect of tert-butylamide 5-chlorothiophene-2-sulfonate?
In today's world, serotonin agonists and 2-thiophenethylaminoamphetone have considerable prospects in the market situation.
Guanfu serotonin agonists have great efficacy in the regulation of neurotransmitters. In today's world, due to the complicated life, heavy pressure, and more and more emotional diseases, such as depression and anxiety, are common. Serotonin agonists can regulate the level of serotonin in the brain and relieve such emotional diseases. And today's medical concept, with the increasing emphasis on the treatment of the mind and body, the demand for such drugs is increasing. From the market perspective, it is not only widely used in the field of adult psychiatry, but also in the treatment of emotional disorders in children and adolescents, and has attracted increasing attention. Medical systems around the world are on the rise in the purchase of such drugs, and their market prospects are like the rising sun, and the light is gradually rising.
As for 2-thiophenethylaminophenone, it is widely used in the field of medicine and chemical industry. In the pharmaceutical sector, it is often a key intermediate and participates in the synthesis of a variety of specific drugs. With the advancement of pharmaceutical technology, the research and development of new drugs has emerged one after another, and the demand for 2-thiophenethylaminophenoacetone has also risen. In the chemical industry, the preparation of many fine chemicals also requires this substance. In addition, the global chemical industry is booming, and the demand for its raw materials continues to grow. The market for 2-thiophenethylaminophenoacetone, such as the vast river, is endless.
To sum up, 5-hydroxytryptamine agonists and 2-thiophenethylaminoacetone are both in response to the needs of the times and have great potential in the market prospect. They are like fertile soil to be cultivated and contain endless business opportunities. When considering the situation, all parties should seize the opportunity and strive for great things.
What are the storage conditions for 5-chlorothiophene-2-sulfonate tert-butylamide?
It is also a tool for healing the disease. The pill is made, and the medallion is in the essence. Even when it comes to the hiding of the medallion, there is also a method. "Tiangong, the hiding of the medallion, the first thing is dryness. In a place where the tide is high, it is easy to make the nature of the medallion, resulting in its effectiveness. Therefore, it is a place where it is high and dry, to avoid the invasion of water.
The second time it is dense. If exposed to the air, the medallion is easily stained by the stain and taste of the medallion, and the oxygen is connected, or the chemical is reversed, and it is damaged. Therefore, it is sealed and hidden in pottery jars and porcelain bottles, so that it can be kept upright.
It is also appropriate to avoid light. Direct light exposure, or promoting the decomposition of the components of the medallion Hidden in the dark, so that it is not exposed to light, the quality can last for a long time.
Furthermore, the degree of loss also needs to be paid attention to. High, the weight may melt, low; low, or make some components of the weight condensation.
In addition, the weight should not be mixed with others. Because of its special nature, or the violation of others, it will change the quality. It must be added to it, so that it can be identified and used. In this way, the weight can be preserved, and it can be used when it is sick, so that it can be used for full performance, so as to survive.