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What fields is 5-mercapto-1H-tetrazole-1-methanesulfonic acid used in?
5-Hydroxy-1H-tetrahydropyrrole-1-acetic acid, this drug has applications in the following fields.
In the context of pharmaceutical research and development, its role is significant. It can be used as a key intermediate for the synthesis of specific drugs. Because of its unique chemical structure, it can interact with specific targets in organisms. For example, in the development of neurological drugs, its structural properties can regulate the transmission process of neurotransmitters. Some innovative drugs for depression and anxiety are developed, and 5-hydroxy-1H-tetrahydropyrrole-1-acetic acid is involved, helping to build effective active ingredients, improve patients' nervous system function, and relieve psychiatric symptoms.
In the field of organic synthesis, it is also an important cornerstone. Organic chemists often use it as a starting material to build complex organic molecular structures through a series of chemical reactions. It is like a key building block for building a molecular building. It is cleverly combined with other organic reagents to construct organic compounds with different functions. For example, when synthesizing organic materials with special optical and electrical properties, 5-hydroxyl-1H-tetrahydropyrrole-1-acetic acid is used as a starting module. Through multi-step reactions, the material is endowed with unique properties, providing the possibility for the development of new organic optoelectronic materials.
In the field of biochemical research, its role should not be underestimated. As a bioactive molecule, it can simulate natural substances in organisms and be used to explore complex metabolic pathways and signal transduction mechanisms in organisms. By introducing this substance, researchers can observe the changes in cell physiological functions and deeply analyze the mysteries of biochemical reactions in cells, providing important support for basic research in life sciences and promoting further deepening of the understanding of the essence of life.
What are the preparation methods of 5-mercapto-1H-tetrazole-1-methanesulfonic acid?
To prepare 5-hydroxymethyl-1H-tetrazole-1-acetic acid, the method is as follows:
First, cyanoacetamide is used as the starting material. First, cyanoacetamide and sodium azide are reacted in a suitable solvent such as dimethylformamide under heating conditions to cyclize to generate 5-cyano-1H-tetrazole. This step requires attention to the control of reaction temperature and time to prevent side reactions from occurring. Then 5-cyano-1H-tetrazole is hydrolyzed, under acidic or basic conditions, the cyano group is converted to carboxyl group, and then the cyano group is reduced to hydroxymethyl group with a suitable reducing agent such as sodium borohydride-lithium chloride system, and finally 5-hydroxymethyl-1H-tetrazole-1-acetic acid is obtained.
Second, formaldehyde and 1H-tetrazole-1-acetic acid are used as raw materials. Under alkali catalysis, such as the presence of sodium hydroxide or potassium carbonate, the activity check point of 1H-tetrazole-1-acetic acid undergoes nucleophilic addition reaction with formaldehyde. The reaction process requires fine regulation of the amount of base and the reaction temperature, because the amount of base and temperature have a great influence on the reaction process and product purity. After subsequent separation and purification steps, the target product can be obtained.
Third, 2-bromomethyl-1H-tetrazole and acetate are used as raw materials. 2-bromomethyl-1H-tetrazole reacts with potassium acetate or sodium acetate in a polar solvent such as acetone. Through nucleophilic substitution mechanism, bromine atoms are replaced by acetate to generate 5-hydroxymethyl-1H-tetrazole-1-acetic acid. In this reaction, the choice of solvent, the molar ratio of reactants and the reaction time are all key factors, which need to be strictly controlled to improve the yield and purity of the product. After the reaction, the pure 5-hydroxymethyl-1H-tetrazole-1-acetic acid was obtained by extraction, recrystallization and other purification methods.
What are the physicochemical properties of 5-mercapto-1H-tetrazole-1-methanesulfonic acid?
5-Hydroxy-1H-tetrahydropyrrole-1-acetic acid, which is an organic compound. The physical and chemical properties of this substance are as follows:
Under normal temperature, it is mostly white to white crystalline powder, which is easy to observe and operate. When it comes to solubility, it is soluble in water and also shows a certain solubility in common organic solvents such as methanol and ethanol. This property determines its application in different reaction systems and preparations.
From the perspective of melting point, it has a specific melting point range, which is of great significance for the identification of its purity and the control of related reaction conditions. As for stability, the properties of the substance are relatively stable in conventional temperature and humidity environments, but if exposed to extreme conditions such as high temperature, high humidity or strong acid and alkali, its structure may change, causing changes in chemical properties.
In terms of chemical properties, this compound has a carboxyl group and a nitrogen-containing heterocyclic structure. The carboxyl group can participate in reactions such as esterification and salt formation. The presence of nitrogen-containing heterocyclic rings gives it a unique electron cloud distribution, allowing it to participate in nucleophilic, electrophilic and other reactions. These reactive activities make it widely used in the field of organic synthesis, and can be used as a key intermediate to construct more complex organic molecular structures. It has shown potential application value in many fields such as medicinal chemistry and materials science.
What is the market price of 5-mercapto-1H-tetrazole-1-methanesulfonic acid?
For 5-% hydroxybenzol-1H-tetrazole-1-acetic acid, the market price varies depending on quality, quantity, and supply. In today's market, its valence state is changeable, and it is difficult to have a definite value.
In terms of its quality, pure and excellent, the price must be higher than that of regular products. If there are few impurities and high purity, it meets a specific standard, or is used in fields such as medicine and chemical experiments with high demand, its price should be expensive.
The amount is also the main reason. If you buy a lot, you can often get a good price. Merchants often use the policy of discounting large quantities to promote quantities. Therefore, the price of bulk purchases is lower than that of a small amount of retail purchases.
Furthermore, the supply situation affects its price. If the demand is greater than the supply, the product is scarce in the market, and there are many people in demand but few goods, the price will increase. On the contrary, if the supply exceeds the demand, the merchant will sell its goods or reduce the price.
It also depends on the origin, manufacturing, etc., which is also related to the price. The cost of raw materials from different origins is different, and the coarse manufacturing process also affects the cost and quality, which ultimately affects the market price. To determine the price of 5-% hydroxybenzene-1H-tetrazole-1-acetic acid, various factors must be carefully considered, and multiple suppliers can be consulted to obtain a near-real price.
What are the storage conditions for 5-mercapto-1H-tetrazole-1-methanesulfonic acid?
5-Hydroxy-1H-tetrahydropyrrole-1-acetic acid, this substance needs to be properly hidden. The method of hiding is related to physical properties and safety.
Although its properties are not detailed, it is known as a fine genus based on its chemical name. When placed in a cool place, avoid the intense sun from the sun. The heat of the sun may cause it to change, resulting in impure quality and loss of efficacy.
And it should be placed in a dry place to prevent the disturbance of moisture. If the moisture invades, or produces the appearance of deliquescence, it will damage its original state, and even lead to various chemical reactions, which will damage its inherent nature.
In addition, it must be contained in a sealed device. Those who seal it must prevent it from coming into contact with external gases. Oxygen, carbon dioxide and other gases in the air may change with them, causing them to deteriorate.
Where this object is hidden, it should also be kept away from fire and heat sources. It may be at risk of explosion, although it is not known for sure, it is necessary to be cautious. The proximity of fire and heat sources, or the unexpected change, endangers the surrounding objects and people.
It needs to be separated from other objects, especially not with chemicals that are in conflict. Different chemicals meet together, or react violently, causing harm.
In the hiding place, a clear sign should be set up to indicate the name, nature and protection of the object. Make it clear to the viewer to prevent accidental touch and misuse, and keep the depositor and the user safe. In this way, the way to properly store 5-hydroxyl-1H-tetrahydropyrrole-1-acetic acid.