5-Mercapto-1H-Tetrazole-1-Methanesulfonic chemical structure of Acid Disodium Salt
5-Mercapto-1H-tetrazole-1-methanesulfonate disodium salt, its chemical structure is as follows. This compound is composed of tetrazole ring, thiol group, methanesulfonate group and sodium ion.
The tetrazole ring is a five-membered heterocyclic structure composed of four nitrogen atoms and one carbon atom, which has high stability and unique chemical activity. 1H - represents the hydrogen atom attached to the nitrogen atom at position 1 of the tetrazole ring.
The thiol group (-SH) is attached to the No. 5 position of the tetrazolium ring, which endows the compound with specific nucleophilicity and reductivity, and is easy to participate in chemical reactions to form thioether bonds or other sulfur-containing compounds.
Methanesulfonic acid group (-CH < SO <) is connected to the nitrogen atom at the No. 1 position of the tetrazolium ring through methylene (-CH < -). The group has strong acidity and hydrophilicity, which can enhance the solubility of the compound in water and make the compound appear ionized in aqueous solution.
The disodium salt form shows that the two dissociable hydrogen ions of the methanesulfonate group are replaced by sodium ions (Na 🥰) to form two pairs of -SO 🥰 Na 🥰 ions. This salt form further enhances the water solubility and stability of the compound, and is conducive to the dissolution, transportation and function of the compound in many chemical reactions and biomedical applications.
In summary, the unique chemical structure of 5-mercapto-1H-tetrazole-1-methanesulfonate disodium salt gives it a variety of chemical and physical properties, which have shown important application value in the fields of medicinal chemistry and organic synthesis.
What are the main uses of 5-Mercapto-1H-Tetrazole-1-Methanesulfonic Acid Disodium Salt?
5-Mercapto-1H-tetrazolium-1-methanesulfonate disodium salt, which is a particularly important chemical substance, has a wide range of uses in many fields.
First, in the field of medicinal chemistry, it is often used as a key intermediate in drug synthesis. In the process of drug development, its unique chemical structure can participate in a variety of reactions, helping to construct molecular structures with specific pharmacological activities. For example, when synthesizing some antibacterial and antiviral drugs, it can be used as a raw material to ingeniously introduce specific functional groups, thereby endowing the drug with better biological activity and pharmacokinetic properties, contributing to the development of human health.
Second, it also plays an important role in the field of materials science. It can be used to prepare functional materials, such as materials with special adsorption properties or catalytic properties. By chemically modifying or compounding with other substances, the properties of materials can be significantly improved. For example, introducing it into polymer materials can endow the material with selective adsorption capacity for specific metal ions, and has great application potential in wastewater treatment, metal ion recovery, etc.
Third, in the field of organic synthetic chemistry, as a unique reagent, it can participate in many organic reactions and provide novel ways for the construction of organic molecules. The sulfhydryl group and tetrazolium structure it contains can trigger a series of unique chemical reactions, which can help to synthesize organic compounds with complex structures and promote the continuous progress and innovation of organic synthetic chemistry.
What is the production method of 5-Mercapto-1H-Tetrazole-1-Methanesulfonic Acid Disodium Salt?
The production method of 5-mercapto-1H-tetrazole-1-methanesulfonate disodium salt is a key technology in chemical preparation. In the past, the preparation of this compound often followed a specific organic synthesis path.
The first step is often to start with nitrogenous and sulfur-containing basic raw materials. If a suitable nitrile compound is selected, the nitrile compound contains carbon and nitrogen three bonds and has high reactivity. With a specific nitrile and sodium azide in a suitable reaction medium, under a specific temperature and catalyst, a cyclization reaction occurs to form tetrazole intermediates. In this reaction process, it is necessary to precisely control the temperature and reaction time. If the temperature is too high, the side reactions will increase, and if it is too low, the reaction rate will be too slow, which will affect the yield.
In the next step, the obtained tetrazole intermediate is reacted with the reagent containing the sulfonic acid group. Specific sulfonating agents, such as chlorosulfonic acid, can be selected. Under appropriate conditions, the sulfonic acid group is introduced into the specific position of the tetrazole ring to generate the tetrazole compound containing the sulfonic acid group. This step requires a high pH of the reaction environment and the purity of the reaction system, otherwise it is easy to cause the introduction of sulfonic acid groups into the position deviation or form impurities.
In the last step, the tetrazole compound containing the sulfonic acid group 5-Mercapto-1H-tetrazole-1-methanesulfonate disodium salt is obtained by reacting with alkali solution such as sodium hydroxide and adjusting the reaction conditions to convert the sulfonic acid group into sodium salt form. This salt formation process requires attention to the concentration and amount of alkali solution, and precise control to obtain high-purity products.
During the preparation process, each step of the reaction requires fine operation, strict control of the reaction conditions, and often needs to be combined with various separation and purification methods, such as recrystallization, column chromatography, etc., to improve the purity and yield of the product.
What are the physical properties of 5-Mercapto-1H-Tetrazole-1-Methanesulfonic Acid Disodium Salt?
The disodium salt of 5-mercapto-1H-tetrazole-1-methanesulfonate is a unique compound. Its physical properties are well-researched.
Looking at its properties, it usually shows the shape of white to off-white crystalline powder under normal conditions, which is easy to identify and operate. When it comes to solubility, it is soluble in water, which makes it very suitable for integration in the reactions or applications of many aqueous systems.
As for the melting point, it is about a specific numerical range. This melting point characteristic is a key indicator in the purity identification and thermal stability research of compounds. Its stability is also considerable, and it can be maintained for a considerable time without significant deterioration in a dry environment at room temperature. However, if it is exposed to moisture, heat or a specific chemical environment, it may change.
Furthermore, the density of this substance is also a certain value, which depends on its distribution and behavior in different media. Its odor is minimal, and its impact on the operating environment is relatively small, which is conducive to related experiments and production processes. These physical properties are of great significance in many fields such as chemical synthesis and pharmaceutical research and development, laying the foundation for its application.
5-Mercapto-1H-Tetrazole-1-Methanesulfonic Acid Disodium Salt during storage and transportation
5-Mercapto-1H-tetrazolium-1-methanesulfonate disodium salt This product must pay attention to many matters during storage and transportation.
First storage environment. This agent should be stored in a cool, dry and well-ventilated place. Due to its chemical properties, high temperature and humid environments are prone to deterioration. If stored at high temperatures, the molecular structure may be affected, causing its activity to change; excessive humidity, or deliquescence, impairing purity and performance.
Furthermore, avoid contact with incompatible substances. This compound has unique chemical activity and may react violently when exposed to specific oxidants, reducing agents or acid-base substances, or risk combustion and explosion. Therefore, when storing, it should be placed separately from such substances, and the warning should be clearly marked in the storage area to prevent accidental mixing.
When transporting, the packaging must be solid and stable. Use suitable packaging materials, such as containers with good sealing and compression resistance, to prevent package damage and drug leakage due to transportation turbulence. At the same time, the transportation process should be temperature-controlled and moisture-proof, and in accordance with chemical transportation specifications, to ensure that the transportation environment meets the requirements.
In addition, personnel must operate in compliance. Personnel who come into contact with this substance should be professionally trained and familiar with its characteristics and safe operation procedures. During storage and transportation, personnel should wear appropriate protective equipment, such as protective gloves, goggles and protective clothing, to prevent the agent from coming into contact with the skin and eyes to ensure personal safety.
In summary, the storage and transportation of 5-mercapto-1H-tetrazole-1-methanesulfonate disodium salt, such as environment, packaging, and operation, are all crucial. Only by following regulations can safety and quality be guaranteed.