5-O-Methanesulfonate-2,3-O-Isopropylidene-2-C-Methyl-D-Ribonic-Gmma-Lactone

5-O-methanesulfonate-2,3-O-isopropylenyl-2-C-methyl-D-ribonucleic acid - γ - lactones are widely used in the field of medicinal chemistry. This compound is often the most important intermediary in organic synthesis.
In the path of drug development, it can be a key building block and help build complex drug molecular structures. Due to its unique chemical structure, it contains specific functional groups and stereochemical characteristics, which can introduce precise chemical modifications for subsequent reactions. For example, the reactivity of methanesulfonate groups can be used to react with various nucleophiles to expand the structural diversity of molecules, so it plays a pivotal role in the creation of novel pharmaceutical active ingredients.
In the field of organic synthetic chemistry, it is often an important starting material for the construction of carbohydrate derivatives and related complex natural product analogs. Through the chemical transformation of its isopropylidene, methyl and lactone structures, a series of compounds with special biological activities or physicochemical properties can be developed. The existence of this compound enriches the strategies and methods of organic synthetic chemistry, enabling chemists to design and synthesize a variety of functional and specific organic molecules, paving the way for the development of medicine, materials science and other fields. Therefore, 5-O-methanesulfonate-2,3-O-isopropylidenyl-2-C-methyl-D-ribonolactone - γ - is an indispensable and important compound in the field of organic synthesis and drug development.

5-O-methylsulfonate-2,3-O-isopropylene-2-C-methyl-D-ribonucleic acid - γ - lactone, an organic compound with unique chemical properties. Among its physical properties, it is mostly solid at room temperature, and the melting point has a specific value due to the intramolecular force. The melting point or in a certain range is determined by the compactness of the molecular structure; the boiling point is related to the strength of the intermolecular force.
In terms of solubility, the compound behaves differently in organic solvents. Because it contains polar methanesulfonate ester group and non-polar hydrocarbon group part, it has a certain solubility in polar organic solvents such as ethanol and acetone, because polar groups can form interactions with solvent molecules; in non-polar organic solvents such as n-hexane, the solubility is low, because the non-polar part interacts weakly with non-polar solvents.
In terms of chemical activity, methanesulfonate ester group has high reactivity. As a good leaving group, it is prone to nucleophilic substitution reaction. Nucleophilic reagents such as alcohols, amines, etc., can attack the carbon atom of the ester group, causing methanesulfonate to leave and form new substitution products. The isopropylene group part is relatively stable, but under acidic or basic conditions, hydrolysis reaction can occur, which destroys the isopropylene group structure and forms a corresponding diol structure. 2-C-methyl and D-ribonucleic acid - γ - lactone part, which affects the overall spatial structure and reactivity of the compound. The lactone ring can open the ring and react under appropriate conditions, showing various chemical properties.

The preparation of 5 - O - methylsulfonate - 2,3 - O - isopropylenyl - 2 - C - methyl - D - ribonucleic acid - γ - is particularly delicate. The first need is to use 2 - C - methyl - D - ribose as the starting material. This substance in the field of organic synthesis, such as rare treasures, has a unique structure, which lays the foundation for subsequent reactions.
First, 2-C-methyl-D-ribose is reacted with acetone under acid catalysis, just like a wise man who has met the master. The two happily combine to form 2,3-O-isopropylene-2-C-methyl-D-ribose. This reaction requires careful temperature control. If the temperature is too high or too low, the reaction can be derailed, such as the ship losing its rudder and deviating from the established course.
Then, the resulting product is reacted with methanesulfonyl chloride in an alkaline environment. The base is like a helmsman, guiding the process of the reaction, so that the methanesulfonyl group precisely replaces the hydroxyl group at the 5-O position, resulting in 5-O-methanesulfonate-2,3-O-isopropylene-2-C-methyl-D-ribose. This step requires strict purity of the reaction environment, and the disturbance of impurities, such as black sheep, can damage the overall situation of the reaction.
Finally, the steps of oxidation and lactonation are like craftsmen carving rough jade to convert it into 5-O-methanesulfonate-2,3-O-isopropylidenyl-2-C-methyl-D-ribonucleic acid - γ - lactone. The oxidation process requires the selection of suitable oxidants, and the dosage is accurate. If it is too much, it will fall short. When lactonation, the reaction conditions also need to be carefully adjusted to obtain this delicate product. The whole preparation process is interlocking, such as the music notes of the movement, all of which are indispensable, and each step needs to be carefully handled to obtain a pure target product.

Today, we are asking about the market price of 5-O-methanesulfonic acid-2,3-O-isopropylidenyl-2-C-methyl-D-ribonucleic acid - γ - lactone. This is a specific compound in the field of fine chemicals. As mentioned in "Tiangong Kaiwu", it is mostly a traditional agricultural and handicraft method, and it does not match the price of such modern fine chemicals.
However, if you want to know the market price of this product, look at the situation of the chemical raw material market. Its price often changes due to many reasons, the first is supply and demand. If there are many people who want it, but there are few products, the price will increase; on the contrary, if the supply exceeds the demand, the price will decrease.
The second is the difficulty of preparation. This compound has an exquisite structure, and the preparation may require complicated steps, special raw materials and conditions. If the preparation is difficult, the cost will be high, and its price will be high.
And there are differences in quality. High purity, because it is more difficult to prepare, is suitable for high-end use, and the price is higher than that of low purity.
In today's chemical market, such compounds may be sold to professional chemical raw material suppliers. If you want to know the exact price, you can consult the chemical product trading platform or directly consult with relevant suppliers to obtain an accurate price to meet your requirements.

5 - O - methylsulfonate - 2,3 - O - isopropylenyl - 2 - C - methyl - D - ribonucleic acid - γ - lactone, is an organic compound. Its storage conditions are crucial, related to the stability and quality of this compound.
According to ancient books and previous experiments, this compound should be stored in a cool, dry and well-ventilated place. If it is cool, it is easy to decompose or deteriorate due to high temperature. If the temperature is too high, the molecular movement will intensify, or the chemical bond will be broken, which will damage its chemical structure and cause its activity to change or inactivate. Therefore, the storage temperature should be controlled between 15 ° C and 25 ° C. This temperature range can ensure the relative stability of its chemical properties.
A dry environment is also indispensable. If this substance encounters water vapor, or reacts such as hydrolysis. Water can be used as a reaction medium to cause hydrolysis between molecules and destroy the original chemical structure. Therefore, the humidity of the storage place should be low, and the relative humidity should not exceed 40%. Desiccants and other substances can be used to maintain the dryness of the environment.
Furthermore, good ventilation can prevent it from contacting with harmful gases or impurities, and it is beneficial for heat dissipation, so that the local temperature is not too high. It should also be noted that it should be placed in a shaded place. Light or photochemical reaction can cause its structure to change. It can be used in brown bottles or containers with light-shielding coatings to prevent adverse effects of light.
When storing, it should also be separated from oxidizing agents, acids, bases, etc. Due to the chemical properties of 5-O-methanesulfonate-2,3-O-isopropylene-2-C-methyl-D-ribonucleic acid - γ - lactones, or violent reactions with the above substances, causing danger, such as fire, explosion, etc.
Storage under the above conditions can maintain good quality and chemical activity of 5-O-mesylate-2,3-O-isopropylene-2-C-methyl-D-ribonucleic acid - γ - for a certain period of time.