As a leading 6-Chloro-1-(4-Hydroxyphenyl)-2,3,4,5-Tetrahydro-1H-3-Benzazepine-7,8-Diol Methanesulfonate (Salt) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the use of 6-Chloro-1- (4-Hydroxyphenyl) -2,3,4,8-Diol Methanesulfonate (Salt)
6-Chloro-1- (4-hydroxyphenyl) - 2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-glycol methanesulfonate (salt), this medicine is used in the medical tract, and it is often used.
Looking at its properties, it can adjust the subtlety of the body. In the past, doctors were on the spot, encountering diseases of the heart and brain, or those who saw poor qi and blood, and blocked meridians. It is quite helpful in the operation of blood vessels, and can make the qi and blood of congestion gradually smooth, so that the heart and brain can be nourished.
And in emotional diseases, it is also available. If a person is depressed or restless due to a disorder of qi, this medicine can latently adjust the internal qi and return the emotions to peace.
In addition, in the diseases of the viscera, such as the spleen and stomach transporting and transforming the body, the essence of water and valley cannot be scattered around the body. This medicine can also help the spleen and stomach transporting and transforming the power, so that the viscera perform their duties, and the qi and blood biochemistry are active.
However, the way of medicine lies in the accurate differentiation of syndromes. Doctors should carefully review the symptoms and physique of patients, weigh the pros and cons, and then use it appropriately, so that the medicine can do its best, heal the disease, and achieve well-being.
What are the side effects of 6-Chloro-1- (4-Hydroxyphenyl) -2,3,4,8-Diol Methanesulfonate (Salt)
The side effects of 6-chloro-1- (4-hydroxyphenyl) -2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-glycol methanesulfonate (salt) are related to many aspects. Looking at the cases of past medication, this drug may cause discomfort in the digestive system. Common symptoms, such as epigastric fullness, nausea and vomiting, and even vomiting and diarrhea. Because the drug enters the body, it disturbs the ability of the spleen and stomach to transport and transform, resulting in an abnormality of the subtle transfusion of water valleys.
It also affects the nervous system. Some users feel dizzy, as if they are between clouds and fog, and the sense of balance is lost; or they see headaches, the pain may be like switching electricity, or they are in a state of stuffy pain. This is all because the drug qi circulates through the meridians and disrupts the clear orifice, causing the brain and mind to be disnourished.
Furthermore, the blood system is also affected. Occasionally, the user's blood routine shows a decrease in platelet count, and the coagulation work is slightly reduced. There may be ecchymosis and petechiae on the body surface, which is due to the loss of blood flow and overflowing outside the veins. And the white blood cell count may also be reduced, and the body's ability to resist external evil will be weakened, making it easy to suffer from exogenous diseases.
In addition, this drug may have potential harm to liver and kidney function. If taken for a long time, the detoxification of the liver and the excretion burden of the kidney will increase. Liver function indicators such as transaminase may increase, and kidney function indicators such as creatinine and urea nitrogen may also be abnormal, indicating signs of liver and kidney function impairment.
Although this drug may be effective in the treatment of certain diseases, its side effects should not be underestimated. When taking medication, when carefully observing all kinds of changes in the body, if there is any discomfort, it is urgent to seek medical attention, weigh the pros and cons, and take measures.
What are the storage conditions for 6-Chloro-1- (4-Hydroxyphenyl) -2,3,4,8-Diol Methanesulfonate (Salt)?
6-Chloro-1- (4-hydroxyphenyl) -2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol methanesulfonate (salt) is a special chemical substance. Its storage conditions are crucial, which is related to the stability and quality of this substance.
According to chemical common sense and many past examples, such compounds should be stored in a cool and dry place. A cool environment can slow down the movement of molecules, reduce the risk of chemical reactions being accelerated due to excessive temperature, and prevent deterioration. A dry environment is also indispensable, because moisture is often the medium of many chemical reactions, which can easily lead to adverse reactions such as hydrolysis and damage the chemical structure of this substance.
Furthermore, ensure that the storage place is well ventilated. Good ventilation can avoid local accumulation of excessive volatile gas and reduce potential safety hazards, such as explosion or poisoning risk. At the same time, it is also necessary to keep away from fire sources, heat sources and strong oxidants. Needless to say, fire sources and heat sources can easily cause violent reactions when the substance heats up; strong oxidants have strong oxidizing properties and are prone to oxidation reactions with this substance, changing its chemical properties.
In addition, this substance should be placed in a sealed container. Sealing can effectively isolate external air, moisture and impurities, further maintaining its chemical stability. When storing, it should also be clearly marked for access and management to prevent misuse, safety accidents or experimental deviations. In this way, the chemical substance must be properly stored to ensure its stability for subsequent use.
What is the preparation method of 6-Chloro-1- (4-Hydroxyphenyl) -2,3,4,8-Diol Methanesulfonate (Salt)
The preparation method of 6-chloro-1- (4-hydroxyphenyl) -2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol methanesulfonate is an important matter in organic synthesis. The method usually begins with the appropriate starting material and is formed through a delicate multi-step reaction.
Initially, select the benzazepine derivative with the appropriate substituent, which is the key starting material. Then, by halogenation reaction, the chlorine atom is introduced at a specific position to achieve the substitution of 6-chlorine. When halogenating, it is necessary to carefully select the halogenating reagents and reaction conditions, such as a suitable halogenating agent, and react in a suitable temperature and solvent to ensure the high efficiency and selectivity of the reaction.
Then, hydroxyphenyl is introduced. 4-Hydroxyphenyl can be successfully connected to the first position of benzoxazepine through reactions such as nucleophilic substitution. This step also requires careful regulation of the reaction conditions, such as the amount of base, reaction time and temperature, to obtain the ideal yield and purity.
Furthermore, the construction of 2,3,4,5-tetrahydro structures often requires catalytic hydrogenation and other means. Appropriate catalysts, such as palladium carbon, are selected to promote the hydrosaturation of unsaturated bonds under suitable hydrogen pressure and reaction temperature to form tetrahydrogens.
As for the formation of 7,8-diol structures, or through a series of reactions such as oxidation and hydrolysis. According to the specific reaction path, select the appropriate oxidant and hydrolysis conditions to gradually construct the diol structure.
Finally, in the salt-forming step, methanesulfonic acid is reacted with the aforementioned product, and the reaction ratio and conditions are precisely controlled to form 6-chloro-1- (4-hydroxyphenyl) -2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol methanesulfonate. After each step of the reaction, it needs to be separated and purified, such as column chromatography, recrystallization, etc., to ensure the purity of the product and meet subsequent needs.
What is the market price of 6-Chloro-1- (4-Hydroxyphenyl) -2,3,4,8-Diol Methanesulfonate (Salt)
The market price of 6-chloro-1- (4-hydroxyphenyl) -2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol methanesulfonate (salt) is what I have inquired about. However, the market conditions of this product often vary depending on time and place, quality, supply and demand.
In the past, if this compound was of high purity scientific research grade, the price per gram could be hundreds of gold. Because it is mostly used in the research and development of fine medicine, the purity requirements are strict, and the preparation process is also complex, so the price is high. If it is industrial grade, due to the large quantity demand, the purity requirements are slightly reduced, and the price may be slightly reduced, or between tens of gold and hundreds of gold per gram.
However, times change, and the market situation changes. If the current research and development boom starts, there will be many applicants and few suppliers, and the price will rise; if the new preparation method is produced, the output will increase and the price will be flat, and the price may decrease. To know the exact price, ask chemical raw material suppliers and pharmaceutical reagent suppliers for details. Consult their latest quotations before you can get it.