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7- (3-aminopyrrolidine-1-yl) -1- (2,4-difluorophenyl) -6-fluoro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzene sulfonate, what is the chemical structure of the hydrate
Guan Jun's question is about the chemical structure of (7- (3-aminophenylpropanone-1-yl) -1- (2,4-dichlorobenzyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzyl ester, hydrate). This is a difficult problem in the field of fine chemistry, let me explain it in detail for you.
Husband (7- (3-aminophenylpropanone-1-yl) -1- (2,4-dichlorobenzyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzyl ester, hydrate), its structure is complex and consists of many parts. First of all, its core skeleton is based on the structure of 1,8-naphthidine. The upper 6 positions are connected to chlorine atoms and the 4 positions are oxo, which have important effects on the properties of compounds. The chlorine atom has electron-absorbing properties, which can affect the distribution of electron clouds, and the oxo-substituted carbonyl group makes the check point have certain reactivity.
The side chain part is connected to 7 positions (3-aminophenylacetone-1-yl). The amino group has the ability to give electrons and can participate in a variety of chemical reactions, such as reacting with electrophilic reagents; the phenylacetone structure adds the hydrophobicity of the compound. 1-position (2,4-dichlorobenzyl), two chlorine atoms further enhance the hydrophobicity and electronic effect of the molecule. The 3-position carboxylic acid forms an ester bond with 4-methyl benzyl ester, which not only affects the solubility of the compound, but also can undergo reactions such as hydrolysis under specific conditions.
Furthermore, the hydrate form indicates that the compound binds to water molecules in a specific way, and the water molecules are connected to the host molecules through weak interactions such as hydrogen bonds, which also has a significant effect on its physical and chemical properties, such as stability and solubility.
In summary, the chemical structure of (7- (3-aminophenylacetone-1-yl) -1- (2,4-dichlorobenzyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzyl ester, hydrate)), each part interacts to determine its unique properties and reactivity.
7- (3-aminopyrrolidine-1-yl) -1- (2,4-difluorophenyl) -6-fluoro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzene sulfonate, what is the main use of hydrate
7- (3-aminopropyl-1-yl) -1- (2,4-dichlorophenyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzene sulfonate and hydrate, its main uses are many.
This compound is often used as a key active ingredient in the pharmaceutical field to develop antibacterial drugs. Due to the special chemical structure of this compound, it can effectively inhibit specific physiological processes of bacteria, such as the synthesis of bacterial cell walls, the replication and transcription of nucleic acids, etc., and has a strong inhibitory and killing ability against a variety of pathogens, so it has important medicinal value in dealing with bacterial infectious diseases.
In the field of chemical research, it can be used as an intermediate for organic synthesis. Through a series of chemical reactions, its structure can be modified to prepare new compounds with different properties and functions, providing a key foundation and material for the development of organic synthetic chemistry.
And because of its unique physical and chemical properties, it has also emerged in the field of materials science. Or it can participate in the preparation of materials with special properties, such as materials with the ability to identify and adsorb specific substances, to open up new paths for the innovation and development of materials science.
7- (3-Aminopyrrolidine-1-yl) -1- (2,4-difluorophenyl) -6-fluoro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzene sulfonate, what are the preparation methods of hydrate
To prepare the compound of 7- (3-hydroxyacetophenone-1-yl) -1- (2,4-dichlorophenyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid-4-methylbenzene sulfonate with water, the method is as follows:
Prepare all the required ingredients and utensils first, and be sure to clean and use them together. Take an appropriate amount of starting materials, such as 3-hydroxyacetophenone-1-yl, 2,4-dichlorophenyl and other related compounds, and weigh them accurately according to a certain proportion. The proportion of the product is related to the purity and yield of the product, so it should not be careless.
Place the raw material in a suitable reaction vessel, which must be able to withstand changes in temperature and pressure during the reaction. Add an appropriate amount of solvent to fully dissolve the raw material and facilitate the reaction. At the same time, add a suitable catalyst, which can accelerate the reaction process, but the dosage also needs to be carefully controlled.
Then, adjust the reaction temperature and pressure to the appropriate environment. When heating up or cooling down, the speed should be slow to allow the reaction system to adapt smoothly. The regulation of pressure should also be precise, not high or low. In this process, it is necessary to pay close attention to the progress of the reaction, or observe the change of its color, the generation of bubbles, or monitor the relevant parameters with instruments.
When the reaction is approaching the expected degree, follow-up treatment can be carried out according to the situation. Or use appropriate methods to separate the product, such as filtration, extraction, etc. After separation, the product or containing impurities needs to be purified by recrystallization or other methods. Purified several times until the product reaches the required purity standard.
Finally, under suitable conditions, the product is combined with water to form the required hydrate. During this process, environmental factors such as humidity and temperature may affect the formation of hydrate, so it needs to be properly controlled. Thus, the compound of 7 - (3 - hydroxyacetophenone - 1 - yl) - 1 - (2,4 - dichlorophenyl) - 6 - chloro - 4 - oxo - 1,8 - naphthidine - 3 - carboxylic acid - 4 - methylbenzene sulfonate with water can be obtained.
7- (3-Aminopyrrolidine-1-yl) -1- (2,4-difluorophenyl) -6-fluoro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzene sulfonate, what is the safety and toxicity of hydrates
There is a compound named 7- (3-hydroxyphenylacetone-1-yl) -1 - (2,4-dichlorophenyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid-4-methylbenzene sulfonate and water. To know the safety and toxicity of this compound, the details are as follows:
The safety of this compound depends on many factors. From the perspective of its chemical composition, the interaction of various groups affects its safety. To determine its safety in different scenarios, many rigorous experiments are required. In an industrial production environment, consider its impact on the operator, such as whether it will cause human discomfort through breathing, skin contact, etc. At the environmental level, after it enters natural water and soil, its impact on the ecosystem should not be underestimated. It is necessary to study its degradation rate and degradation products in the environment to understand its potential harm to environmental organisms.
Talking about toxicity, the groups composed of chlorine, oxygen and other elements contained in this compound may be potentially toxic. The presence of chlorine atoms may cause specific chemical reactions in organisms and interfere with normal physiological processes. And structures such as naphthalidine and benzene rings may also interact with biological macromolecules. However, the exact degree of toxicity also needs to be determined by animal experiments, cell experiments, etc. to determine its half lethal dose, half inhibitory concentration and other indicators to accurately evaluate its toxicity to different organisms.
In summary, in order to fully know the 7 - (3-hydroxyphenylacetone-1-yl) -1 - (2,4-dichlorophenyl) -6-chloro-4-oxo-1,8 - naphthidine-3-carboxylic acid 4-methylbenzene sulfonate and hydrocarbons, it is necessary to rely on systematic scientific experimental research and comprehensive factors to reach an accurate conclusion.
7- (3-Aminopyrrolidine-1-yl) -1- (2,4-difluorophenyl) -6-fluoro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzene sulfonate, hydrate What is the price range in the market?
I think what you are talking about is a compound of chemically related substances, but the description is a little complicated. Such 7- (3-hydroxyacetone-1-yl) -1 - (2,4-dichlorophenyl) -6-chloro-4-oxo-1,8-naphthidine-3-carboxylic acid 4-methylbenzenesulfonic anhydride and water compounds are in the market price range, and it is difficult to determine the exact number.
Because of the market price, it is often affected by many factors. First and foremost, the cost of raw materials. The difficulty of obtaining raw materials and the amount of output will cause cost fluctuations, which in turn affects the price of finished products. If raw materials are scarce and difficult to harvest, their price will be high; conversely, if raw materials are abundant and easy to obtain, the price may be relatively low.
Furthermore, the production process is also the key. Although complex and sophisticated processes can produce high-quality things, they require more manpower, material resources, and financial resources, and the cost will rise, and the price will be high.
In addition, the supply and demand relationship in the market is also the baton of price. If the demand for this product is strong and the supply is limited, the merchant will raise the price to obtain a large profit; if the supply exceeds the demand, the price may be greatly reduced in order to sell the inventory.
There is more market competition, the number of congeneric products, the advantages and disadvantages of competing products, etc., will make merchants adjust the price to compete for the market. Coupled with regional differences and the influence of policies and regulations, it is difficult to accurately define this compound in the market price range, or it fluctuates within a large range, making it difficult to generalize.