(8Xi,12'Xi)-2-Bromo-12'-Hydroxy-2'-(1-Methylethyl)-5'-(2-Methylpropyl)-3',6',18-Trioxoergotaman Methanesulfonate (Salt)

Looking at the chemical name of " (8Xi, 12 'Xi) -2 -bromo-12' -hydroxy-2 '- (1-methylethyl) -5' - (2-methylpropyl) -3 ', 6', 18 -trioxo ergotane methanesulfonate (salt) ", in order to clarify its chemical structure, it is similar to dismantling a natural artifact, and it needs to follow the rules of organic chemistry.
This compound belongs to ergotane derivatives. First look at the parent nucleus of ergotane, which has a unique multi-ring structure, like the cornerstone of an exquisite pavilion. In the second position, there are bromine atoms, which seem to add a delicate decoration to the pavilion. The introduction of bromine atoms will change its chemical activity and physical properties. At the 12 'position, the hydroxyl group is attached, and the hydroxyl group is also a hydrophilic group, which can increase the property of the compound and water, and is also an active check point in chemical reactions.
2' position is connected to (1-methylethyl), that is, isopropyl, which adds a slightly larger side chain to the parent nucleus, which affects the spatial arrangement and hydrophobicity of the molecule. 5 'position (2-methylpropyl), that is, isobutyl, this side chain further enriches the spatial structure of the molecule and has a non-negligible impact on intermolecular forces and physical properties.
Furthermore, 3', 6 ', 18-trioxo, this is the introduction of carbonyl at a specific position. Carbonyl is polar, which not only changes the electron cloud distribution of the molecule, but also affects the stability and reactivity of the compound. The methanesulfonate part, which is an ionic structure, can enhance the solubility of the compound in water, and also plays an important role in its pharmacological activity and in vivo processes.
In summary, the chemical structure of this compound is derived from the ergothane mother nucleus, and each substituent is cleverly arranged, giving it unique physical and chemical properties. It is just like a natural creation, exquisite and exquisite, and all parts cooperate to achieve a unique chemical entity.

This is called 2-bromo-12 '-hydroxy-2' - (1-methylethyl) -5 '- (2-methylpropyl) -3', 6 ', 18-trioxo ergot methanesulfonate. Its physical properties are as follows:
Under normal conditions, or in a solid state, it is mostly powdery, delicate and uniform. Looking at its color, it is often white to off-white, pure and free of variegated colors, like the first snow in winter, clean and elegant.
When it comes to solubility, it shows its unique properties in organic solvents. In alcoholic solvents, such as ethanol, it can show a certain dissolution trend, just like salt melts in water, quietly disperses, and gradually becomes a homogeneous phase; in some polar organic solvents, such as dimethyl sulfoxide, the solubility is also considerable, and it can be quickly dispersed and fused with it. However, in water, its solubility may be slightly inferior, only slightly soluble, like the ping in water, and it is difficult to completely disappear.
The genus of melting point is also an important physical characteristic. Its melting point may be in a specific temperature range, which is obtained by fine measurement, which is one of the key markers for identifying this substance.
In addition, the stability of this substance to light and heat is also worthy of careful investigation. Under light, it may gradually change, and the color, structure, etc. may change subtly; when heated, it reaches a certain temperature, or triggers a change in chemical structure, causing its physical properties to change accordingly.
In summary, 2-bromo-12 '-hydroxy-2' - (1-methylethyl) -5 '- (2-methylpropyl) -3', 6 ', 18-trioxo ergot methanesulfonate shows its own unique properties in terms of physical properties, such as its appearance, solubility, melting point and stability.

288Xi, 12 ′ Xi - 2 - bromo - 12 ′ - hydroxy - 2 ′ - (1 - methylethyl) - 5 ′ - (2 - methylpropyl) - 3 ′, 6 ′, 18 - trioxo ergot methanesulfonate (salt), this medicine is important to doctors and has unique pharmacological uses.
In the human body, it can regulate many physiological states. It can act on the pathway of nerves and affect the transmission of neurotransmitters, just like messengers communicating between pathways, making the transmission of information more orderly, stabilizing the operation of the nervous system, or relieving some neurological diseases, such as headache, vertigo, etc.
In addition, it also has the power to regulate blood vessels. Like a water control ability, it can dredge the "water flow" of blood vessels, regulate the relaxation and contraction of blood vessels, improve blood circulation, and send sufficient nutrients to all corners of the body to maintain its vitality. Or it can be used to relieve discomfort caused by abnormal blood vessels, such as ischemia, poor blood flow and other diseases.
And this drug also has a subtle effect on endocrine. Just like a dispatching officer, fine-tuning the secretion of endocrine glands, maintaining hormone balance, making the body's metabolism, growth, development and other processes smooth, so that the body's functions are like delicate instruments, orderly operation.
Its pharmacological effects are extensive and complex. When treating, physicians must carefully review the patient's condition, weigh the pros and cons, and use it accurately to obtain its good effects, help patients recover, and rejuvenate.

(8Xi, 12 ′ Xi) - 2 - bromo - 12 ′ - hydroxy - 2 ′ - (1 - methylethyl) - 5 ′ - (2 - methylpropyl) - 3 ′, 6 ′, 18 - trioxo ergothylamine methane sulfonate (salt), this drug is widely used in clinical applications.
It can be used to relieve migraine. The symptoms of migraine, when the headache is splitting, are often accompanied by nausea, vomiting, photophobia, phobia, etc. This drug can effectively curb the attack of migraine and relieve the pain of patients.
It is also of great value in the treatment of hyperprolactinemia. Hyperprolactinemia can cause women's menstrual disorders, lactation, and male sexual dysfunction. The drug can regulate the level of prolactin, make the endocrine gradually normalize, and relieve various symptoms.
In addition, it is also helpful for the treatment of Parkinson's disease. Parkinson's disease patients often have tremor, myotonia, and motor retardation. This drug can improve the patient's motor function and improve their ability to take care of themselves.
It is also a commonly used drug in postpartum lactation. If there is no need for breastfeeding or rapid lactation after childbirth, this drug can play an effective role in reducing milk secretion and preventing discomfort such as breast tenderness.
When applying this drug clinically, doctors should accurately grasp the dosage and course of treatment according to the patient's specific condition, constitution and other factors, and pay close attention to the patient's medication response to ensure safety and efficacy.

288Xi, 12 ′ Xi - 2 - bromo - 12 ′ - hydroxy - 2 ′ - (1 - methyl ethyl) - 5 ′ - (2 - methyl propyl) - 3 ′, 6 ′, 18 - trioxo ergotane methanesulfonate (salt), the common adverse reactions of this drug have been described by predecessors. However, there are also many cases, and no adverse response has been seen.
Among the many people who use this drug, some people have specific endowments. After the drug is entered into the body, the qi and blood are reconciled, the meridians are smooth, and there is no discomfort. If the body is weak but the vitality is not injured, after taking the medicine, the spirit will gradually recover, and the body will not be in harmony. There are also signs of the beginning of the disease, when the evil energy is not in full bloom, this medicine will be used to treat it, and the infection will be opened and closed in an orderly manner, without inducing internal evil, and there will be no adverse changes.
And if when taking the medicine, the diet and daily life are properly adjusted, and it conforms to the changes of yin and yang in the four times, it can also reduce the adverse response. For example, in the spring, when the yang qi rises, if the user can go to bed early and get up early, and go out more in the countryside, so that the emotion will be comfortable, the effect of the medicine can be smooth, and there will be less For example, during the medication period, the diet is light, less spicy and thick-tasting things are eaten, the spleen and stomach are transported normally, and the drug absorption and metabolism are orderly, so there can be no adverse reactions.
However, everyone's physical condition varies, and the reaction after medication varies widely. Although there are many situations that may not cause adverse reactions, doctors still need to use medication carefully according to the specific situation of the patient. Medications should also follow the doctor's advice and carefully observe their own changes to ensure the safety of medication.