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What is the main effect of Calcium Polystyrene Sulphonate?
Calcium polystyrene sulfonate has the following main effects:
In the human body, this medicine can adjust the balance of electrolytes. Cover the electrolytes of the human body, and it is related to the normal operation of various physiological functions. If the electrolytes are unbalanced, diseases will occur. Calcium polystyrene sulfonate can be combined with excess potassium ions in the body and excreted through the intestines. Potassium ions play an important role in the maintenance of the function of many important organs such as the human heart and muscles. However, when the blood potassium concentration is too high, that is, hyperkalemia, the electrophysiological activity of the heart is disturbed, arrhythmia may occur, and even life is endangered. Calcium polystyrene sulfonate can just solve this dilemma. Through the mechanism of ion exchange, potassium ions are replaced, lowering blood potassium to the normal range, protecting the safety of organs such as the heart, so that the heart rhythm is normal, muscle strength is also restored to its normal state, and the ability of physical exercise is guaranteed.
Furthermore, in patients with chronic kidney disease and acute kidney injury, the function of kidney excretion of potassium ions is impaired, and blood potassium is easily increased. Calcium polystyrene sulfonate can escort it, help control blood potassium levels, and delay the progression of the disease. And this drug is convenient to use, mostly in oral dosage form, and patient compliance is relatively good. Therefore, calcium polystyrene sulfonate, with its ability to regulate electrolytes and control blood potassium, is a powerful medicine for doctors to treat diseases and treat diseases, protect patients' health, and prevent them from hyperkalemia and other diseases.
Calcium Polystyrene Sulphonate Side Effects
Calcium polystyrene sulfonate is a medicine for treating hyperkalemia, but it also has various side effects.
First, in the gastrointestinal tract, nausea and vomiting are common. This is after the drug is introduced into the body, it stimulates the mucosa of the gastrointestinal tract, causing stomach gas to go up, so nausea. And the properties or ingredients of the drug can also affect the normal transportation of the gastrointestinal tract, causing nausea.
Second, constipation is not uncommon. Calcium polystyrene sulfonate in the intestine changes the properties and transmission of intestinal contents, hinders the smooth passage of feces, and imbalances the absorption of intestinal water, resulting in dry stool and difficulty in excretion.
Third, long-term or excessive use can cause hypokalemia. The drug exchanges potassium ions in the intestines, excessively removing potassium ions, the potassium ion balance of the human body is broken, the blood potassium concentration is reduced, and many functions such as neuromuscular and heart are affected.
Fourth, the drug may affect the balance of other electrolytes. In addition to potassium ions, such as calcium ions, magnesium ions, etc., or the content in the body fluctuates due to the action of the drug, interfering with the normal physiological functions of the body.
Fifth, some patients have local skin or allergic reactions after taking the drug. Some ingredients of the drug may be allergens, causing skin itching, erythema, etc., due to the individual's allergic constitution.
Anyone who uses the drug should carefully monitor their own reactions and seek medical attention for appropriate treatment if serious side effects occur.
What is the correct use of Calcium Polystyrene Sulphonate?
Calcium polystyrene sulfonate is a good medicine used by doctors to treat hyperkalemia. Its usage is quite exquisite, and it should be based on the specific condition of the patient and the prudent judgment of the doctor.
Generally speaking, in the case of acute hyperkalemia, this medicine can be mixed into a paste with an appropriate amount of water and given to the patient by oral or nasal feeding. When taking orally, the initial dose for adults is about 15 to 30 grams, which can be repeated every 1 to 2 hours, but the total amount of daily feeding rarely exceeds 100 grams. The amount of nasal feeding is also roughly similar. It is necessary to pay attention to closely monitor the blood potassium level and gastrointestinal reactions of the patient after administration.
If it is the treatment of chronic hyperkalemia, the dose may be slightly reduced. Adults usually start with about 15 grams per day, and the dose should be moderately increased or decreased according to the results of blood potassium testing. Children need to calculate the dose carefully according to their body weight. Generally, about 0.5 to 1 gram per kilogram of body weight is used, and it is divided into multiple oral or nasal feeds.
When taking medication, be sure to tell the patient to drink an appropriate amount of water to help the drug transport and effect in the intestines, and to prevent the risk of constipation. At the same time, medical practitioners should regularly check the blood potassium, blood calcium and other electrolytes levels of the patient in order to adjust the medication strategy in a timely manner. Due to improper use or excessive blood calcium, other electrolyte disorders and other adverse reactions, the whole process of medication needs to be rigorous and cautious to ensure the safety and efficacy of patient medication.
Which groups of people is Calcium Polystyrene Sulphonate suitable for?
Calcium polystyrene sulfonate is a good medicine used by physicians, and it is suitable for many people. It is especially suitable for those with high blood potassium due to renal failure. Kidney, the main water metabolism, is responsible for excretion. If kidney failure, potassium ion excretion is blocked, blood potassium rises. Calcium polystyrene sulfonate can be in the intestines and exchanged with potassium ions, so that potassium comes out with feces, in order to reduce the concentration of blood potassium, to protect the safety of the body.
Furthermore, patients with chronic kidney disease and blood potassium is often high can also be used. Chronic kidney disease persists and is difficult to heal, kidney excretion function is gradually weakened, and blood potassium is easy to accumulate. This medicine can slow down the rise of blood potassium and help patients maintain the stability of the internal environment.
In addition, people who have suddenly increased blood potassium due to drugs or other factors can also rely on this drug to relieve danger. If some patients accidentally take some drugs that affect potassium metabolism and blood potassium rises sharply, calcium polystyrene sulfonate can take effect quickly, reduce blood potassium, and avoid other changes.
When taking medication, doctors should carefully review the patient's physical condition, weigh the pros and cons, and determine the dosage and frequency of the medication to ensure that the medication is effective and safe.
Does Calcium Polystyrene Sulphonate Interact with Other Drugs?
Calcium polystyrene sulfonate, when taking drugs, it is often necessary to observe the interaction between it and other drugs. The properties of this drug are related to the metabolic balance of calcium and potassium in the body.
If used with digitalis drugs, be careful. In digitalis, the main heart rhythm is regulated, but calcium polystyrene sulfonate can cause changes in blood calcium, changes in blood calcium, or disturb the effect of digitalis on the myocardium. If blood calcium rises, it may increase the toxicity of digitalis, causing a sudden increase in heart rhythm disorders, such as premature ventricular beats, ventricular tachycardia, etc.
When used in combination with sodium-containing drugs, attention should also be paid. Calcium polystyrene sulfonate reduces blood potassium at the same time, or increases sodium intake. If the patient has a sodium retention disease, such as cardiac insufficiency, kidney failure and water and sodium metabolism disorders, this combination may exacerbate edema and increase blood pressure, which is unfavorable to the condition.
In addition, when taken with alkaline drugs, its interaction should not be underestimated. The alkaline environment can affect the ion exchange function of calcium polystyrene sulfonate, resulting in a weakened effect of lowering blood potassium, making it difficult to achieve the expected effect.
When a doctor uses drugs, he must carefully review the patient's symptoms and the drugs used, weigh the pros and cons, prevent the harm of drug interactions, and seek the best treatment effect, so as to benefit the patient and avoid disasters.