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What is the chemical structure of Methyl-P-Tolysulfonate Cis- [2,4-Dichlorophenyl) -2- (1H-Imidazol-1-Ylmethyl) -1,3-Dioxalan-4-Yl]?
This is an organic compound with a rather complex chemical structure. According to its naming rules, it can be dissected step by step.
"Cis - [2,4-dichlorophenyl] -2- (1H-imidazole-1-ylmethyl) -1,3-dioxolane-4-yl] methyl-p-toluenesulfonate". The first word "Cis" indicates that the compound has a cis-configuration. "[2,4-dichlorophenyl]", showing a benzene ring, with a chlorine atom at the 2nd and 4th positions. " 2 - (1H-imidazole-1-ylmethyl) ", that is, the second position of the 1,3-dioxane ring is connected with a group, this group is 1H-imidazole-1-ylmethyl, 1H-imidazole is a five-membered heterocyclic ring containing two nitrogen atoms, one of which is connected to the methyl group at the first position." 1,3-dioxane-4-yl] methyl ", indicating that the fourth position of the 1,3-dioxane ring is connected with a methyl group. The "p-toluenesulfonate" refers to the anionic part connected to the above part. The p-toluenesulfonate group is composed of p-methylbenzene and a sulfonic acid group, and the negative charge of the sulfonic acid group forms a salt with the front cationic part.
In this compound structure, it contains a variety of cyclic structures such as benzene ring, heterocyclic ring and dioxane ring, and there are many substituents such as chlorine atom, methyl group and imidazole group. Each part is connected according to specific rules to form a unique chemical structure. Its spatial configuration is cis, and the spatial arrangement and interaction of each atom and group have important effects on its physical and chemical properties and biological activities.
What are the main uses of Cis- [2,4-Dichlorophenyl) -2- (1H-Imidazol-1-Ylmethyl) -1,3-Dioxalan-4-Yl] Methyl-P-Tolysulfonate?
This is the name of the chemical substance, which can be called cis- [2,4-dichlorophenyl] -2- (1H-imidazole-1-ylmethyl) -1,3-dioxolane-4-yl] methyl-p-toluenesulfonate in Chinese. It is mainly widely used and is often used as a key intermediate in the field of pharmaceutical synthesis. Due to the special chemical structure of this substance, it can be cleverly combined with other compounds through specific chemical reactions to form complex molecules with specific pharmacological activities, paving the way for the creation of new drugs.
In the field of materials science, it also has its uses. Or it can be combined with other materials through special treatment to give the material new properties, such as enhancing the stability of the material and improving its solubility, so as to expand the application scenarios of the material.
In the process of scientific research and exploration, this substance is also an important research object. By studying its physical and chemical properties, reactivity, etc., researchers can gain in-depth insight into the relevant chemical reaction mechanism, which adds to the improvement of chemical theory and provides a solid foundation for the development of more efficient synthesis methods. In short, this chemical substance plays an important role in many fields and is of great significance in promoting the progress of science and technology.
What are the production methods of Cis- [2,4-Dichlorophenyl) -2- (1H-Imidazol-1-Ylmethyl) -1,3-Dioxalan-4-Yl] Methyl-P-Tolysulfonate?
The method of preparing cis- [2,4-dichlorophenyl] -2- (1H-imidazole-1-ylmethyl) -1,3-dioxy-amyl-4-yl] methyl-p-toluenesulfonate has several ways.
One, or can be started with the corresponding alcohol. First, the alcohol containing 2,4-dichlorophenyl and 1,3-dioxy-amyl-4-yl structures is reacted with p-toluenesulfonyl chloride under appropriate conditions. This reaction requires the selection of a suitable solvent, such as pyridine, which can neutralize the hydrogen chloride generated by the reaction, so that the reaction proceeds in the positive direction. The temperature during the reaction also needs to be finely adjusted, and room temperature or slightly lower than room temperature is appropriate to prevent side reactions from occurring. After this reaction, the hydroxyl group of the alcohol can be replaced by p-toluenesulfonyloxy to obtain the target product.
Second, it can also be started from compounds containing imidazole structures. First, the halogen containing 2,4-dichlorophenyl and 1,3-dioxyamyl-4-yl is reacted with 1H-imidazole under basic conditions, so that the nitrogen atom of the imidazole is substituted with the halogen atom of the halogen to form an intermediate containing imidazole-1-yl methyl structure. Subsequently, the intermediate is then reacted with p-toluenesulfonate ester reagents to finally form the target product. In this process, the choice of basic conditions is crucial, such as inorganic bases such as potassium carbonate and sodium carbonate, or organic bases such as triethylamine, which need to be determined according to the specific situation of the reaction.
Or the strategy of constructing a 1,3-dioxyamyl ring structure can be used. First, an aldehyde or ketone containing 2,4-dichlorophenyl and 1H-imidazole-1-methyl was prepared to form a 1,3-dioxyamyl ring structure with ethylene glycol under acid catalysis, and then reacted with p-toluenesulfonyl reagent. After a series of reaction steps, cis-[ 2,4-dichlorophenyl] -2 - (1H-imidazole-1-ylmethyl) -1,3-dioxyamyl-4-yl] methyl-p-toluenesulfonate can be obtained. In this route, factors such as the type and amount of acid catalysts, reaction time and temperature all have significant effects on the yield and selectivity of the reaction.
Cis- [2,4-Dichlorophenyl) -2- (1H-Imidazol-1-Ylmethyl) -1,3-Dioxalan-4-Yl] Methyl-P-Tolysulfonate What are the precautions during use?
Alas! Fu Cis - [2,4-dichlorophenyl) - 2- (1H-imidazole-1-ylmethyl) - 1,3-dioxolane-4-yl] methyl-p-toluenesulfonate. When using this substance, all kinds of things should be paid attention to.
First, its nature is also sensitive, and it is easy to change when exposed to light, heat or moisture. Therefore, when hiding, it must be placed in a dark, cool and dry place to prevent its quality from changing. If exposed to light or heated too much, it may lose its effectiveness or even cause other harm.
The second time, the method used must be applied according to the prescription. The amount and the order of time are all fixed. Excessive use may cause symptoms of toxicity; if the dosage is insufficient, it will be difficult to achieve its effect. And the method used must also be stable and accurate, so as not to spill or stain other things.
Furthermore, if it is followed by it, the matter of protection should not be ignored. Apply protective equipment, such as gloves, masks, goggles, etc. Because of its irritating and corrosive properties, it can cause injuries when it touches the body and skin, and when it enters the eyes and nose.
In addition, after use, it must be clean and properly handled. Residues should not be discarded indiscriminately, and should be disposed of according to regulations to prevent contamination of the ring and harm to all living beings.
In short, when using Cis - [2,4-dichlorophenyl) - 2- (1H-imidazole-1-ylmethyl) - 1,3-dioxyamyl-4-yl] methyl-p-toluene sulfonate, it should be used with caution in storage, use, protection, and handling.
What is the market outlook for Cis- [2,4-Dichlorophenyl) -2- (1H-Imidazol-1-Ylmethyl) -1,3-Dioxalan-4-Yl] Methyl-P-Tolysulfonate?
The market prospect of [2,4-dichlorophenyl] -2 - (1H-imidazole-1-ylmethyl) -1,3-dioxolane-4-yl] methyl-p-toluenesulfonate is the focus of attention.
From the perspective of the industry, the demand for this product is gradually increasing in the chemical and pharmaceutical industry. Because of its unique chemical structure, it can be a key intermediate in the synthesis of medicine and can participate in the preparation process of a variety of specific drugs. For example, in the development of antifungal drugs, it can be used as a core raw material to help develop more efficient agents to deal with various fungal infections, so pharmaceutical companies are increasingly interested in purchasing this material.
Furthermore, in the field of materials science, it may be able to improve the properties of materials by virtue of its own characteristics. For example, in the synthesis process of some polymer materials, adding this material may optimize the stability, corrosion resistance and other key properties of the material, making the related materials in industrial production, construction engineering and other fields have a wider application space, thereby stimulating the market demand for it.
Of course, the competition in the market is also becoming increasingly fierce. Many chemical companies, aware of the potential business opportunities of this product, have invested resources to carry out related research and development and production. Although this promotes the development of the industry, it also leads to an increase in the number of supplies and fluctuations in market prices. And with the rapid development of science and technology, the emergence of new synthetic methods and alternative products has also added many variables to the market prospects of this product.
If companies want to gain a place in the Sri Lankan market, they need to focus on technological innovation, improve product quality, and reduce production costs. At the same time, pay close attention to market dynamics and adjust business strategies in a timely manner in order to adapt to changes in the market, take the lead in the fierce competition, and enjoy the dividends of this market development.