What is the use of Colistinmethanesulfonic Acid, Sodium Salt?
Colistinmethanesulfonic Acid, Sodium Salt (polymyxin E sodium methanesulfonate) is an antibacterial drug, which is widely used in the medical tract.
First, it is used to treat serious infections caused by Gram-negative bacteria. Such as Pseudomonas aeruginosa, Escherichia coli and other lung infections caused by these bacteria, which ravage the lungs and cause patients to cough, fever and difficulty breathing. Polymyxin E sodium methanesulfonate can enter the lung meridian, directly attack the bacteria, inhibit their growth and reproduction, help the lung to spread and reduce the function of recovery, make breathing smooth, heat relief and cough.
Second, it is also effective against urinary system infections. When bacteria invade the kidneys, bladder and other urinary organs, causing frequent urination, urgency, urinary pain and other diseases, this medicine can follow the meridians into the lower coke, eliminate the evil poison of the urinary system, restore the transparency of the waterway, and relieve all kinds of discomfort.
Third, it is also indispensable in the treatment of sepsis. In sepsis, bacteria enter the blood and run around the body, endangering life. Polymyxin E sodium methanesulfonate can enter the blood, clear the blood of heat poison, kill bacteria, make qi and blood flow smoothly, and save the patient in danger.
When using this medicine, caution is also required. Because of its possible nephrotoxicity and other drawbacks, improper use may damage the kidney and cause kidney qi deficiency. Doctors should carefully review the patient's physique and condition, weigh the pros and cons, and use the drug rationally, so that the drug can exert its healing power and avoid its harm.
What are the side effects of Colistinmethanesulfonic Acid and Sodium Salt?
Colistin sodium methanesulfonate, although it is an antibacterial drug, it also has various side effects, which cannot be ignored.
One of its side effects is nephrotoxicity. With this drug, the burden on the kidneys may increase, and renal tubular function may be damaged. Common symptoms include proteinuria, hematuria, tubular urine, etc., and even kidney insufficiency. Gu Yun: "Kidney is a strong official, and it is clever." Kidney health is related to various functions of the human body. If the kidneys are damaged by drugs, the consequences are worrying.
The second is neurotoxicity. This drug may affect the nervous system, causing dizziness, headache, fatigue, and may also cause blurred vision and ataxia. "The eye is the envoy of the heart, and the heart is the place of the gods." Vision and mental thinking are disturbed, and life and work are affected. And in severe cases, it can cause respiratory depression, which is life-threatening and cannot be underestimated.
Third, it also affects the gastrointestinal tract. After medication, nausea, vomiting, diarrhea and other symptoms are common, and the functions of the spleen and stomach are blocked. The spleen and stomach are the foundation of the acquired day, the source of qi and blood biochemistry, and the spleen and stomach are out of harmony. Nutrient intake and qi and blood production are implicated, resulting in weakness.
Fourth, allergic reactions cannot be ignored. Or there are symptoms such as rash and itching, and in severe cases, it can cause anaphylactic shock. "The skin, the appearance is also, and the outside is the solid." Skin allergies, not only itching is intolerable, but anaphylactic shock can be life-threatening. When taking medication, the doctor should weigh the pros and cons and handle them cautiously. Patients should also pay close attention to their own reactions. If there is any abnormality, inform the doctor to ensure the safety of the medication.
Colistinmethanesulfonic Acid, Sodium Salt are suitable for
Colistinmethanesulfonic Acid (Sodium Salt) is suitable for patients with multi-drug resistant Gram-negative bacterial infections, mostly in critical condition and those who have failed conventional antimicrobial therapy.
This drug is often used in patients in intensive care units (ICUs) because they often suffer from serious infections and the pathogen has a high rate of resistance to common antibiotics. For example, in patients with respirator-associated pneumonia, if the infection produces ultra-broad-spectrum β-lactamase (ESBLs) Enterobacteriaceae bacteria, conventional β-lactam antibiotics are difficult to work. Colistin sodium mesylate may be tried.
It is also suitable for patients with intestinal flora imbalance caused by long-term hospitalization or repeated use of antibacterial drugs, which leads to infection by drug-resistant Gram-negative bacteria. For example, in patients with leukemia, the immunity is low due to chemotherapy, the intestinal barrier is damaged, and the infection is susceptible to drug-resistant bacteria. Colistin sodium mesylate may be able to control the infection.
In addition, in patients with urinary system infections, if the pathogenic bacteria are resistant to commonly used quinolones and cephalosporins, colistin sodium mesylate may be used as a rescue treatment drug. However, due to its nephrotoxicity and neurotoxicity, the advantages and disadvantages should be weighed when using the drug, and the patient's renal function and nervous system symptoms should be closely monitored. It is contraindicated for those with colistin allergy, and the dose should be adjusted cautiously in the elderly,
Colistinmethanesulfonic Acid and Sodium Salt
Colistinmethanesulfonic Acid and Sodium Salt, it is also a product. If you want to use it properly, the first person to follow the rules. The dosage and usage are determined according to the patient's symptoms, age, and other factors such as illness and other diseases.
If it is taken orally, it is often taken with a large amount of water, so that the patient can swallow it according to the rules, and do not miss or exceed the dosage. During the use period, it is necessary to closely observe the reaction of the patient, such as adverse reactions, such as stomach diseases such as heart, vomiting, abdominal problems, or skin rash, skin and other sensitive symptoms.
If it is used for injection, it must be done by the person in the right place, according to the appropriate bacteria operation. The speed and amount of injection are all safe and should not be ignored. And the injection should also be done to the patient's safety to prevent sudden damage.
In addition, the preservation of this safety is also important. It should be placed in the dry, dry and children's safety, to avoid high and tidal light, so as to avoid damage. Therefore, the use of Colistinmethanesulfonic Acid and Sodium Salt must be followed, and caution can be used to avoid harm.
What are the storage conditions for Colistinmethanesulfonic Acid, Sodium Salt?
Colistinmethanesulfonic Acid, Sodium Salt is a drug, and its storage conditions are extremely important, which is related to the efficacy and quality of the drug. This drug should be stored in a cool and dark place, the so-called cool and dark, covering a place not exceeding 20 ° C and shading light. In this way, it can be protected from direct light, causing the components to decompose and deteriorate.
It is also necessary to keep the environment dry. If the moisture is heavy, or the drug is damp, it will cause deliquescence and mildew, which will damage its effectiveness. And it should be placed out of the reach of children to prevent accidental ingestion and adverse consequences.
Furthermore, it should be stored separately from other drugs to avoid mutual contamination or chemical reactions. After use, it should also be sealed immediately and must not be left open for a long time to prevent excessive contact with air and affect the quality. Proper storage conditions are followed to ensure the stability of the efficacy of Colistinmethanesulfonic Acid, Sodium Salt for clinical or other purposes.