Daos; Sodium 3-((3,5-Dimethoxyphenyl)(Ethyl)Amino)-2-Hydroxypropane-1-Sulfonate

This compound is named 3- [ (3,5 -dimethoxyphenyl) (ethyl) amino] -2 -hydroxypropane-1 -sodium sulfonate, and its chemical structure is as follows:
- ** Core skeleton **: Propane-based carbon chain, that is, three carbon atoms are connected in sequence to form the main chain, the structure of propane is $CH_3 - CH_2 - CH_3 $.
- ** Functional group modification **:
- ** Hydroxyl substitution **: Hydroxyl ($-OH $) is introduced on the carbon atom of propane at position 2, and the structure becomes $CH_3 - CH (OH) - CH_3 $.
- ** Sulfonic acid group and sodium salt modification **: The sulfonic acid group ($- SO_3H $) is attached to the carbon atom at position 1 and further forms a sodium salt, which becomes $- SO_3Na $, and the structure is $CH_3 - CH (OH) - CH_2 - SO_3Na $.
- ** Amino substitution **: The carbon atom at position 3 is connected to an amino ($-NH - $) group, and the two ends of the amino group are connected to specific groups, one end is 3,5 -dimethoxyphenyl, the 3,5 positions of this phenyl are substituted by methoxy ($- OCH_3 $); the other end is connected to ethyl ($- C_2H_5 $) to form $N - $ (3,5 -dimethoxyphenyl) - $N - $ethylamino structure, and is connected to the carbon atom at position 3. The final complete chemical structure is presented as: $CH_3 - CH (OH) - CH_2 - SO_3Na $, where the carbon atom at position 3 is connected to $N - $ (3,5-dimethoxyphenyl) - $N - $ethylamino. In this way, the atoms and groups are joined in a specific order by covalent bonds to construct the unique chemical structure of 3- [ (3,5-dimethoxyphenyl) (ethyl) amino] -2-hydroxypropane-1-sulfonate sodium.

Sodium 3- ((3,5-Dimethoxyphenyl) (Ethyl) Amino) -2-Hydroxypropane-1-Sulfonate, the Chinese name is often called 3- (N-ethyl-N- (3,5-dimethoxybenzyl) amino) -2-hydroxypropanesulfonate sodium, this substance has a wide range of uses.
In the field of biochemical research, it can be used as a biological buffer. Because of its good acid-base buffering ability, it can maintain the stability of the pH of the solution within a specific pH range, thus providing a suitable microenvironment for biochemical reactions. Many enzymatic reactions are extremely sensitive to environmental pH, and a slight deviation will affect the activity and reaction process of enzymes. This substance can ensure the smooth progress of the reaction under suitable pH conditions, and help researchers to more accurately explore the characteristics and functions of biomolecules.
It also has important uses in drug research and development. In the process of drug synthesis, it can participate as a reaction aid to help adjust the pH of the reaction system, promote the synthesis and conversion of drug intermediates, and improve the yield and purity of the reaction. At the same time, because of its good solubility and stability, it can be used to adjust the pH value of the preparation in pharmaceutical preparations, enhance the stability and bioavailability of drugs, and ensure the quality and efficacy of drugs in vivo and outside.
In the field of chemical production, it can act as a functional additive in the preparation of some special chemicals. For example, in the synthesis of some surfactants, the addition of this substance can optimize the performance of the surfactant, improve its solubility, dispersion, and emulsification ability in different environments, thereby improving the quality and application effect of the product and expanding the scope of application of the product.

Sodium 3- ((3,5-dimethoxyphenyl) (ethyl) amino) - 2-hydroxypropane-1-sulfonate, this is an organic compound. Its physicochemical properties are very important and related to its many applications.
Looking at its solubility, this compound may have some solubility in water. The cover contains a sulfonate group in its structure, which is hydrophilic and can promote the compound to interact with water molecules, thereby dissolving in the aqueous phase.
When it comes to stability, under normal conditions, its structure may be relatively stable. However, under extreme conditions such as high temperature, strong acid, and strong base, structural changes may be triggered. For example, in a strong acid environment, the amino group or hydroxyl group may undergo a protonation reaction, causing the molecular charge distribution to change, which in turn affects its chemical properties; under strong alkali conditions, or initiate reactions such as hydrolysis of ester bonds (if there is a similar structure), destroying the original structure of the molecule.
Let's talk about the melting point and boiling point. The melting point and boiling point of this compound are determined by the intermolecular force. Intermolecular interactions such as van der Waals force and hydrogen bond exist. Because of the hydroxyl group, intermolecular hydrogen bonds can be formed, which enhances the intermolecular force and increases the melting point and boiling point. The specific value needs to be accurately determined experimentally.
In addition, its spectral properties are also considerable. In infrared spectroscopy, functional groups such as hydroxyl groups, etheric bonds, and amino groups all generate absorption peaks at specific wavenumbers, which can be used to identify molecular structures. In nuclear magnetic resonance spectroscopy, hydrogen or carbon atoms in different chemical environments will exhibit specific chemical shifts, providing key information for structure analysis. In short, the physical and chemical properties of this compound are complex and diverse, and in-depth investigation of it is helpful to fully grasp its characteristics and applications.

To prepare Sodium 3- ((3,5-dimethoxyphenyl) (ethyl) amino) -2-hydroxypropane-1-sulfonate, the common preparation methods are as follows:
First, it can be started from 3,5-dimethoxyacetophenone. First, 3,5-dimethoxyacetophenone and ethylamine are condensed under suitable conditions to form the corresponding imine intermediate. In this step, attention should be paid to the reaction temperature and the ratio of reactants to prevent the growth of side reactions. Subsequently, the imine intermediate is nucleophilic addition reaction with 2,3-epoxy propanesulfonate sodium. During the reaction, appropriate solvents and catalysts need to be selected to promote the smooth progress of the reaction, and then the target product is generated.
Second, 3,5-dimethoxyaniline is used as the starting material. It is reacted with bromoethane to achieve N-ethylation to generate N-ethyl-3,5-dimethoxyaniline. This reaction requires the participation of a base to advance the reaction with acid binding. Then, N-ethyl-3,5-dimethoxyaniline is reacted with 2,3-epoxy propanesulfonate sodium in a suitable solvent, and nucleophilic substitution is performed to obtain Sodium 3- ((3,5-dimethoxyphenyl) (ethyl) amino) -2-hydroxypropane-1-sulfonate.
Third, it can be started from 3,5-dimethoxybenzaldehyde. First condensed with ethylamine to obtain imine, and then reacted with 2-hydroxy-3-chloropropanesulfonate sodium. This process requires high control of reaction conditions, such as temperature, pH, etc., to obtain high-purity products.
All kinds of production methods have advantages and disadvantages. In actual preparation, the optimal path is selected when considering various factors such as raw material availability, cost, and product purity.

Sodium 3- ((3,5 -dimethoxyphenyl) (ethyl) amino) -2 -hydroxypropane-1 -sulfonate, this is a very important chemical reagent. During use, there are many key precautions that need to be treated with caution.
First, it is related to storage. This reagent is quite sensitive to environmental conditions and should be properly placed in a dry and cool place. In a humid environment, it is easy to cause moisture and deterioration, which in turn affects its chemical properties and use efficiency. Excessive temperature may also cause adverse reactions such as decomposition. Therefore, the temperature of the storage place should be controlled within a specific range to prevent its quality from being damaged.
Second, the operation must be fine. Due to its unique chemical properties, when taking it, the utensils used must be clean and dry to avoid impurities from mixing in. The weighing process should be accurate and accurate according to the experimental requirements, and there must be no sloppiness. Otherwise, the dosage deviation or the deviation of the experimental results will be far, affecting the accuracy and reliability of the experiment.
Third, safety protection should not be underestimated. Although there is no conclusive evidence that it is highly toxic, the principle of caution should still be adhered to. When operating, it is advisable to wear appropriate protective equipment, such as laboratory clothes, gloves and protective glasses. If you accidentally come into contact with the skin or eyes, you should immediately rinse with plenty of water and seek medical treatment as appropriate.
Fourth, disposal of waste is also regulated. The remaining reagents after use must not be discarded at will. They should be properly classified and disposed of in accordance with relevant chemical waste disposal regulations to avoid pollution and harm to the environment.
In short, when using sodium 3- (3,5-dimethoxyphenyl) (ethyl) amino) -2-hydroxypropane-1-sulfonate, every link from storage, access, safety protection to disposal cannot be ignored, so as to ensure the smooth progress of the experiment, while ensuring the safety of personnel and the environment is not damaged.