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What is the chemical structure of potassium 2,2 '-piperazine-1,4-diethylsulfonate (Dipotassium 2,2' -Piperazine-1,4-Diyldiethanesulfonate)?
2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8%E9%92%BE, its English name is Dipotassium 2,2 '-Piperazine-1, 4-Diyldiethanesulfonate, which is a chemical substance. The chemical properties can be described as follows:
This substance contains piperazine, piperazine, and six-membered piperazine, which are alternately formed by nitrogen atoms of four carbon atoms. At the 1,4 position of piperazine, there are 2-ethanesulfonic acid groups connected. Every 2-ethanesulfonic acid group is formed by the phase of ethyl sulfonic acid. In the sulfonic acid group, the sulfur atom is composed of three oxygen atoms with oxygen atoms, and one oxygen atom has a charge, which can be formed into hydrogen atoms. Because of the sulfonic acid group, there is a phase of hydrogen, so there is a phase of hydrogen, so it is neutral.
For example, the chemical reaction of 2,2 '-piperazine-1,4-diyl diethylenesulfonic acid is based on the core of piperazine, which is terminated with a 2-ethylenesulfonic acid group. The charge phase of the sulfonic acid group is combined.
In which fields is potassium 2,2 '-Piperazine-1,4-diethylsulfonate (Dipotassium 2,2' -Piperazine-1,4-Diyldiethanesulfonate) used more?
2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8%E9%92%BE, that is, 2,2 '-piperazine-1,4-diethylsulfonate dipotassium salt, is widely used in many fields such as biology and medicine.
In the field of biological experiments, it is often used as a buffer. Chemical reactions in organisms are extremely sensitive to pH value, and small changes may affect the reaction process and biological macromolecule activity. This substance can effectively maintain the stability of pH value of the system, providing a suitable acid-base environment for enzymatic reactions, protein crystallization and other experiments. Because of its good buffering ability and chemical stability, it can ensure constant experimental conditions and improve experimental repeatability and reliability.
It is also common in the field of pharmaceutical research and development. In the process of drug preparation, in order to ensure the stability and effectiveness of drugs, it is necessary to precisely control the pH value. As a buffer component, this substance can prevent the degradation or inactivation of drugs due to pH changes, which is of great significance for improving the quality and efficacy of drugs. Some injections, eye drops and other pharmaceutical preparations use this substance to adjust the pH value, reduce the irritation of drugs to the body, and enhance the comfort and compliance of patients with medication.
In the field of cell culture, its importance cannot be underestimated. Cell growth requires strict environmental pH values. 2,2 '-piperazine-1,4-diethylsulfonate dipotassium salt can create a stable pH environment, meet the needs of cell growth, and help cells grow and proliferate healthily in vitro. It is widely used in various cell line culture and cell biology research.
What are the main physical properties of potassium 2,2 '-Piperazine-1,4-diethylsulfonate (Dipotassium 2,2' -Piperazine-1,4-Diyldiethanesulfonate)?
2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8%E9%92%BE, the English name is Dipotassium 2,2 '-Piperazine-1,4-Diyldiethanesulfonate, often referred to as PIPES potassium salt. This physical property is special and related to many aspects.
Its shape is mostly white crystalline powder, which is pure in appearance and has no variegated colors. In terms of solubility, it is easily soluble in water and melts when entering water. It is like ice and snow in the warm sun, which melts in an instant, and has poor solubility in organic solvents. This characteristic makes it unique in the application of aqueous solutions.
Thermal stability is also an important physical property. Under normal conditions, it is quite stable, but it is heated to a specific temperature, or there is a risk of decomposition. This temperature limit needs to be accurately grasped, which is related to its application in different scenarios.
Its pH-related properties cannot be ignored. As a buffer, it can effectively maintain the pH stability of the system in a specific pH range. It is usually suitable for pH ranges of 6.1-7.5, just like a loyal guard, guarding the pH balance of the system.
And the chemical properties of this substance are relatively stable, and it is not easy to react with common substances at will. However, in the case of extreme chemical environments such as strong oxidants and strong acids and alkalis, there may be changes. When applying, careful consideration should be given to the types of substances in contact with it. All these properties are of critical significance in the fields of biochemical research, pharmaceutical preparations, etc., and must be observed by the application.
What are the production methods of potassium 2,2 '-Piperazine-1,4-diethylsulfonate (Dipotassium 2,2' -Piperazine-1,4-Diyldiethanesulfonate)?
2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8%E9%92%BE (Dipotassium 2%2C2%27-Piperazine-1%2C4-Diyldiethanesulfonate), known as PIPES, is commonly used in biochemical research. The method of this method has a slight end.
First, piperazine is used as the starting material. The amount of piperazine in ethanesulfonic acid, such as bromoethanesulfonic acid, is suitable for solution, such as alcohols or non-alcoholic solutions. In the case of low-performance components, nuclei can be generated and substituted. Anti-oxidation, etc., can be used to promote the nitrogen atom of piperazine to attack the carbon atom of ethanesulfonic acid to form carbon and nitrogen, and to obtain medium 2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8. And, with the reverse of oxidation and other substances, the sulfonic acid group is substituted by the sulfonic acid group to obtain 2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8%E9%92%BE.
Second, 1% 2C4-bis (2-ethyl) piperazine can also be synthesized first, and then the sulfonic acid group should be synthesized. First, 1% 2C4-bis (2-ethyl) piperazine can be obtained from piperazine-oxyethane. And, with appropriate sulfonation, such as chlorosulfonic acid, sulfuric acid, etc., the sulfonation reaction is performed, and the sulfonic acid group is introduced at the end of the sulfuric group. Most importantly, the same reason is that the sulfonic acid is synthesized by sulfonic acid to complete the synthesis of 2%2C2%27-%E5%93%8C%E5%97%AA-1%2C4-%E4%BA%8C%E4%B9%99%E7%A3%BA%E9%85%B8%E9%92%BE.
In this way, it is necessary to pay attention to the control of the reaction parts, such as the degree, reaction, material ratio, etc., in order to ensure the reaction and improve the yield of the product.
What is the approximate market price of potassium 2,2 '-Piperazine-1,4-diethylsulfonate (Dipotassium 2,2' -Piperazine-1,4-Diyldiethanesulfonate)?
Today I have a question, what is the price of 2,2 '-piperazine-1,4-diethylsulfonate dipotassium salt in the market? This is a commonly used reagent for biochemical experiments, and its price varies depending on quality, quantity and supplier.
If you buy a small amount, such as excellent grade pure and the quantity is hundreds of grams, the price may be in the hundreds of gold at ordinary biochemical reagent dealers. However, if you want a large amount, up to kilograms, for industrial grade, the price should be based on wholesale regulations, per kilogram or thousands of gold.
And its price is also affected by the supply and demand, origin and brand of the market. Refined by famous factories, those with high quality and strict inspection will have high prices; while those from unknown factories may be slightly cheaper, but the quality may be unpredictable.
Furthermore, if you buy it in different places, the price will be different. In a prosperous city, there are many merchants, and the competition is fierce, or there are goods with excellent price; in a remote place, it is less difficult to transport, and the price may increase. Therefore, if you want to know the exact price, you must consult all reagents, compare their price and quality, and then you can get a good and suitable choice.