Disodium (3Z)-5-Amino-6-[(E)-{4'-[(E)-(2,4-Diaminophenyl)Diazenyl]Biphenyl-4-Yl}Diazenyl]-4-Oxo-3-(Phenylhydrazono)-3,4-Dihydronaphthalene-2,7-Disulfonate

(3Z) - 5-hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) carbonyl] bibenzyl-4-yl} carbonyl] - 4-oxo-3- (benzylimino) - 3,4-dihydronaphthalene-2,7-dipotassium diacid, this substance has a wide range of uses. In the field of medicine, it may have unique pharmacological activities or can be used in the human body by specific mechanisms to assist in the treatment of diseases. For example, it affects the cellular pathways involved in specific diseases, regulates physiological processes, and thus exerts therapeutic effects. In the field of materials science, due to its own chemical structure and characteristics, it may become a key raw material for the construction of new functional materials. After rational design and synthesis, it is expected to endow materials with special optical, electrical or mechanical properties, and to emerge in optical devices, electronic components, etc. In the chemical industry, it can be used as an important intermediate in organic synthesis, and can be converted into other more complex and specific functional compounds by means of chemical reactions, providing support for the diversified production of chemical products.
Looking at its chemical structure, polyfunctional groups coexist, and each functional group synergistically endows the substance with diverse reactivity and physicochemical properties, which is also the fundamental reason why it can be used in many fields. Hydroxyl groups can participate in the formation of hydrogen bonds, which affects the solubility of substances and the interaction between molecules; carbonyl groups and oxygen groups are active in chemical reactions and are key check points for building new chemical bonds and synthesizing new substances; benzyl groups and other groups have effects on the spatial structure and hydrophobicity of substances. The interweaving of various characteristics has laid the foundation for the important use of (3Z) - 5 - hydroxy - 6- [ (E) - {4 '- [ (E) - (2,4 - dihydroxybenzyl) carbonyl] bibenzyl - 4 - yl} carbonyl] - 4 - oxo - 3 - (benzylimino) - 3,4 - dihydronaphthalene - 2,7 - dipotassium diacid in different fields.

(3Z) -5-hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) methoxy] bibenzyl-4-yl} methoxy] -4-oxo-3- (benzylamino) -3,4-dihydrochromene-2,7-dicarboxylate dipotassium, this compound has many unique physical properties.
Looking at its morphology, it is mostly crystalline under normal circumstances, and the crystalline structure is regular and orderly, like a naturally carved miniature crystal world. Its color is often white to light yellow, with pure color and no variegated interference, giving people a sense of simplicity.
In terms of solubility, it exhibits good solubility in polar organic solvents, such as common ethanol and methanol. In ethanol, with the increase of temperature, the solubility increases significantly, just like the gradual melting of ice and snow in the warm sun. This characteristic is due to the existence of multiple polar groups in its molecular structure, which form a strong interaction force with polar solvent molecules.
In water, its solubility is relatively low, because although the water molecule is polar, the compound molecule is large and partially hydrophobic, which hinders its full fusion with water molecules. The melting point of
is also one of the important physical properties. After measurement, the melting point of the compound is in a specific range. At this temperature, the interaction between molecules is broken, the lattice structure disintegrates, and the solid state changes to the liquid state. The stability of the melting point reflects the stability and regularity of its molecular structure.
In addition, it may also have a certain acidity and alkalinity in the solution, which is closely related to the hydroxyl group, carboxyl group and other groups in the molecular structure. Hydroxyl groups can weakly ionize hydrogen ions, while carboxyl groups can obviously release hydrogen ions, making the solution appear acidic. These characteristics play an important role in different chemical environments.

(3Z) -5-Hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) methylene] bibenzyl-4-yl} methylene] -4 -oxo-3- (benzylimino) -3,4-dihydro-2,7-naphthalene dicarboxylic acid, this is a complex organic compound. Its chemical properties are unique, let me talk about it in detail.
First, its solubility, this compound contains hydroxy, carboxyl and other polar groups, in polar solvents such as water and alcohol, or has a certain solubility. However, its molecules are large and have more non-polar aromatic ring structures, so the solubility in non-polar solvents such as alkanes is low.
Then talk about its acidity and alkalinity. The carboxyl group can ionize hydrogen ions, showing acidity. And the hydroxyl group can also reflect weak acidity under specific conditions. On the other hand, the nitrogen atom in the imino group has a lone pair of electrons, which can accept protons and is alkaline to a certain extent. This acid-base amphoteric makes it exist in different forms and reactivity under different acid and base environments.
Its redox properties cannot be ignored. The hydroxyl groups in the molecule are easily oxidized, especially under the action of strong oxidants, or converted into higher valence oxygen-containing functional groups such as aldehyde groups and carboxyl groups. At the same time, the aromatic ring structure may undergo hydrogenation and reduction reaction under specific conditions, which can change the molecular structure and properties.
In addition, because it contains multiple unsaturated bonds, including carbon-carbon double bonds and methylene double bonds, addition reactions can occur. Electrophilic reagents or nucleophiles may attack these double bonds and initiate the formation of various addition products. The aromatic ring part may also undergo substitution reactions, such as halogenation, nitrification, etc., which are affected by the localization effect of substituents, and the reaction check point has a certain selectivity.
In conclusion, (3Z) -5-hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) methylene] bibenzyl-4-yl} methylene] -4 -oxo-3- (benzylimino) -3,4 -dihydro-2,7 -naphthalene dicarboxylic acids are rich in chemical properties and may have potential application value in the fields of organic synthesis and pharmaceutical chemistry.

About (3Z) -5-hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) imine] bibenzyl-4-yl} imine] -4-oxo-3- (benzylimino) -3,4-dihydroquinazoline-2,7-dipotassium diacid Storage and transportation precautions
This medicine is a rare agent, and its storage and transportation should be handled with caution to ensure that its medicinal properties are not damaged and its efficacy is as usual.
When storing, it is advisable to choose a cool and dry place. If it is in a humid place, water vapor is easy to invade, and it may cause mildew and loss of medicinal properties. The temperature also needs to be paid attention to. If it is too high, the molecules will be restless, and the drug will easily dissipate; if it is too low, it will cause the drug body to coagulate, which will affect its properties. Therefore, it is advisable to maintain a moderate temperature, about [specific temperature range]. And it needs to be placed in a place protected from light, where light and heat are forced, and the drug is easy to decompose and deteriorate.
When transporting, the first thing to ensure is that the packaging is intact. This medicine is delicate, and it can be damaged by bumps and collisions. The packaging should be firm and firm, and it can withstand the shock on the way. The transporter also needs to be careful, handle it with care, and must not be reckless. In addition, the transportation environment should also follow the storage regulations, keeping it cool, dry, protected from light and heat insulation. The transportation equipment used must be clean and dye-free to Only with such careful care can this medicine preserve its properties and relieve the disease for the patient during storage and transportation.

Preparation of (3Z) - 5 -hydroxy-6- [ (E) - {4 '- [ (E) - (2,4 -dihydroxybenzyl) methylamino] bibenzyl-4-yl} methylamine] - 4 -oxo-3- (benzylimino) - 3,4 -dihydropteridine-2,7 -dipotassium diacid
To prepare (3Z) - 5 -hydroxy-6- [ (E) - {4' - [ (E) - (2,4 -di Hydroxybenzyl) methyleneamine] bibenzyl-4-yl} methyleneamine] -4-oxo-3- (benzyleneimino) -3,4-dihydropteridine-2,7-dipotassium diacid, which can be done as follows.
First take an appropriate amount of 2,4-dihydroxybenzaldehyde, mix it with a nitrogen-containing compound in a suitable organic solvent in a certain molar ratio, and use acid or base as a catalyst. Stir the reaction at a moderate temperature to form (E) - (2,4-dihydroxybenzyl) methyleneamine-related intermediates. This step requires attention to the control of reaction temperature and time. If the temperature is too high or the time is too long, it is easy to cause side reactions and affect the purity and yield of the product.
Then, the obtained intermediate is reacted with 4-halogenated bibenzyl derivatives in an alkaline environment and in the presence of a phase transfer catalyst. The creation of an alkaline environment can be aided by bases such as sodium hydroxide and potassium carbonate, and phase transfer catalysts such as tetrabutylammonium bromide, etc., so that the reaction can proceed smoothly under milder conditions, and 4 '- [ (E) - (2,4-dihydroxybenzyl) methyleneamine] bibenzyl-4-yl related products can be obtained. In this process, the control of the pH of the reaction system and the amount of catalyst is very critical, which will significantly affect the reaction rate and selectivity.
Next, the above products are condensed with pteridine derivatives containing specific substituents under suitable reaction conditions and promoted by a condensing agent. The condensation agent can be selected as dicyclohexyl carbodiimide (DCC), etc., and the reaction is carried out in organic solvents such as dichloromethane. At this stage, the reaction conditions should be strictly controlled to ensure the complete reaction and prevent the disturbance of side reactions.
Finally, the obtained crude product is separated and purified by column chromatography, recrystallization, etc., to obtain purified (3Z) - 5-hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) methylamino] bibenzyl-4-yl} methylamino] -4-oxo-3- (benzylimino) -3,4-dihydropteridine-2,7-diacid, and then reacts with potassium hydroxide or potassium carbonate to form the corresponding dipotassium salt. When separating and purifying, it is necessary to select and adapt according to the characteristics of the product to achieve the ideal purity and yield.
In this way, (3Z) -5-hydroxy-6- [ (E) - {4 '- [ (E) - (2,4-dihydroxybenzyl) methylamino] bibenzyl-4-yl} methylamino] -4-oxo-3- (benzylimino) -3,4-dihydropteridine-2,7-dipotassium diacid can be prepared.