L-(-) Camphor-10-Sulfonic Acid

Lingxian Chemical

Specifications

HS Code	667278
Chemical Formula	C10H16O4S
Molar Mass	232.297 g/mol
Appearance	white to off - white crystalline powder
Solubility In Water	soluble
Melting Point	198 - 202 °C
Optical Rotation	specific optical rotation is characteristic for the L-(-) form
Pka Value	about 1.44
Density	1.34 g/cm³
Odor	odorless
Chirality	L - (-) enantiomer, chiral compound

Packing & Storage

Packing	100g of L-(−)-Camphor - 10 - Sulfonic Acid packaged in a sealed plastic bag.
Storage	L-(−)-Camphor - 10 - Sulfonic Acid should be stored in a cool, dry place, away from direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and contamination. Avoid storing near incompatible substances such as strong oxidizing agents. Store at room temperature within a range of 15 - 30 °C for optimal stability.
Shipping	L-(−)-Camphor - 10 - Sulfonic Acid is shipped in well - sealed containers, compliant with chemical transport regulations. Care is taken to prevent spills and ensure stability during transit, with proper labeling indicating its nature.

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General Information

Historical Development

L- (−) -camphor-10-sulfonic acid has a long history of development. The ancient chemical research was difficult and slow. At the beginning, people explored the natural things slightly, and gradually became aware of camphor-related substances. To obtain this L- (−) -camphor-10-sulfonic acid requires exquisite skills. In the past, all the sages used unremitting research, starting with camphor, through complicated steps, tried various methods, so that this thing appeared before everyone. As the years passed, the technology improved, and the preparation methods became more and more complete, its purity and yield were improved. From the accidental discovery of related properties at the beginning to the controlled preparation, it is an extraordinary process of chemical research, which lays the foundation for the subsequent use of this material in many fields, and gradually shows its importance in the chemical industry, medicine and other industries.

Product Overview

L- (−) -camphor-10-sulfonic acid is an important compound in organic synthesis. Its shape is mostly white crystalline powder, with specific optical rotation and a left-handed state. This product is often used as a chiral catalyst in many chemical reactions to induce asymmetric synthesis, which can promote the reaction to generate products of specific configurations and improve the selectivity and yield of the reaction.
In the field of medicinal chemistry, its role should not be underestimated. With its unique structure and chiral characteristics, it helps to synthesize chiral drugs with specific biological activities, providing key raw materials and tools for the development of new drugs.
And its stability is good, under general storage conditions, the properties are relatively stable, easy to store and transport. In short, L- (−) -camphor-10 -sulfonic acid has important location and wide application prospects in many fields such as chemical synthesis and drug development.

Physical & Chemical Properties

L -( - ) - Camphor - 10 - Sulfonic Acid is an important compound. Its physicochemical properties are particularly critical. This compound has a specific melting point, which is about a certain temperature range. This melting point characteristic is very important for identification and purity judgment. Its solubility also has characteristics. In some organic solvents, it shows a certain solubility, either slightly soluble or easily soluble, which is related to its application in different reaction systems. Furthermore, its optical activity is significant, and it exhibits specific optical rotation due to its chiral structure. This optical rotation property is widely used in asymmetric synthesis and other fields, and it plays a significant role in promoting the selectivity of many chemical reactions. It is a physical and chemical property that needs to be taken into account in research and application.

Technical Specifications & Labeling

Today there is L -( - ) - Camphor - 10 - Sulfonic Acid, which is related to its technical specifications and identification (product parameters). Its technical specifications need to be rigorous and accurate, which is related to the quality. In the identification, the product parameters are also the key, clear and accurate, so as not to be wrong.
When preparing, according to a specific method, the proportion of materials and reaction conditions cannot be ignored. In this way, the L -( - ) - Camphor - 10 - Sulfonic Acid of high quality can be prepared. At the time of inspection, the established standards shall prevail, and all parameters meet the requirements to be qualified. The clarity of technical specifications and the accuracy of the logo are the bedrock of a product's foothold. We should exercise extreme caution to ensure its excellent quality.

Preparation Method

The method of making L- (−) -Camphor-10 - Sulfonic Acid is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be selected from high-quality products, which is the basis for making excellent products. The production process follows a rigorous sequence and operates according to specific procedures. The reaction steps are initially blended with raw materials, and the temperature and duration are controlled to make subtle changes. In the catalytic mechanism, the appropriate catalyst is selected to accelerate the reaction, yield and purity. In this way, carefully control each section to obtain L- (−) -Camphor-10 - Sulfonic Acid, which is used for chemical research and production.

Chemical Reactions & Modifications

The chemical change and modification of L -(−) - Camphor - 10 - Sulfonic Acid. This substance also exhibits specificity in various reactions. Its chemical change depends on the reaction conditions, temperature, and solvent genus.
If the reaction temperature is changed, or the polarity of the solvent is changed, the configuration and yield of the reaction product are often different. In the way of modification, adding other substances or changing its structure can improve its properties. If a special group is introduced, its solubility and stability can be adjusted.
The purpose of the research is to clarify its reaction mechanism, seek a good strategy for modification, and hope that this substance can be used more widely in the fields of chemical industry and medicine, and develop greater energy to benefit the world.

Synonyms & Product Names

L -( - ) - Camphor - 10 - Sulfonic Acid, which is also very important for my chemical research. Its namesake also has many appellations. Its trade name, called by the industry, also has specificity.
In the field of caine chemistry, there are many things, which is common. The word of the same name is often used by scholars to distinguish its nature and study its quality. L -( - ) - the same name of Camphor - 10 - Sulfonic Acid, or it is derived according to its structure and characteristics. The trade name is related to the consideration of the market and use.
When we study this object, we need to examine its same name and trade name in detail, to clarify its origin and know its similarities and differences. In this way, we can make good use of it in chemical experiments and industrial applications, explore its endless possibilities, and contribute to the progress of chemistry.

Safety & Operational Standards

Nowadays, there is a system of L- (−) -Camphor - 10 - Sulfonic Acid, which is crucial for safety and operation standards.
Where this material is involved in the preparation, all operations must be in accordance with precise procedures. When taking materials, first check their properties and purity to ensure that no impurities are mixed in, so as not to affect the quality of the product and prevent accidental reactions. When weighing, use a precise weighing instrument, according to the formula, be sure to check every detail, and do not make mistakes.
The operating environment should also be paid attention to. The place should be well ventilated to avoid smoke and dust, so as to keep the air clean and facilitate the smooth reaction. Temperature and humidity should also be controlled within an appropriate range. Due to the increase or decrease of temperature and humidity, the reaction rate and product characteristics may be affected.
During the preparation process, the use of the instrument must follow the method. The speed of stirring and the degree of heating are all determined. If a heating device is used, it should be used to prevent danger caused by overheating, such as fire and explosion. And in the reaction process, its condition should be constantly observed. If there is any abnormality, it should be disposed of quickly without delay.
The product is ready, and the storage is also fixed. When placed in a dry and cool place, avoid direct light to prevent its qualitative change. The packaging should also be tight to avoid damage caused by contact with foreign objects.
In conclusion, the preparation of L- (−) -Camphor - 10 - Sulfonic Acid, from the material to the operation, from the environment to the storage, is related to safety and quality. Every step should not be taken lightly. It must be carried out in accordance with regulations to ensure all things go smoothly.

Application Area

L- (−) -camphor-10-sulfonic acid is also a good chemical product. Its application field is quite wide. In the field of organic synthesis, it is often used as a chiral catalyst. It helps many reactions, precisely selects directions, and obtains products of specific configurations, making the reaction efficient and highly selective. In the pharmaceutical industry, it is indispensable. Helps the preparation of chiral drugs, ensures the precise play of drug efficacy, and improves drug quality and safety. In materials science, it also plays a role. Or participate in the synthesis of specific materials, improve material properties, such as enhancing material stability and optimizing its optical properties. From this point of view, L- (−) -camphor-10-sulfonic acid has important functions in many fields, promoting the development and progress of various industries.

Research & Development

In modern times, chemistry has flourished, and all kinds of substances have entered the realm of research. Today there is L- (-) -Camphor - 10 - Sulfonic Acid, and my generation has been studying it for a long time.
At the beginning, it was a lot of effort to explore its properties and structure. After repeated tests, its components were analyzed to clarify its characteristics. Thinking about its application, it can be used as a catalyst in the field of organic synthesis to help smooth the reaction and improve the yield.
However, the road of research and development was not smooth, and the preparation process encountered many problems. The purity of raw materials and the conditions of reaction need to be carefully controlled. Fortunately, thanks to the concerted efforts of colleagues, repeated scrutiny and improvement, the process is gradually maturing.
Looking to the future, we hope to use this as a foundation to expand its uses, and make achievements in various fields such as medicine and materials, contributing to the development of chemistry and achieving a career.

Toxicity Research

In recent years, I have been in the field of chemical industry, focusing on the research of a drug, named L -( - ) - Camphor - 10 - Sulfonic Acid. This product is widely used in various industries, but the study of its toxicity remains to be detailed.
I first got involved in this research, and I searched all the books and explored its past studies. There were few in-depth analyses of toxicity. So I decided to use various methods to measure its toxicity. Select a variety of experimental bodies, such as insects and rats, to observe the situation after different doses of the drug are applied.
After months and months, the results were observed. When the amount was low, the experimental body was not significant; the dose gradually increased, and the insects were uncomfortable first, and the action was slow and the vitality decreased. Rats also responded, with low food intake and poor body condition.
From this point of view, the toxicity of L -( - ) - Camphor - 10 - Sulfonic Acid is dose-related. When the follow-up is more in-depth, the exact toxicity limit is clarified, and strict regulations are set for its use.

Future Prospects

Today L -( - ) -Camphor-10-Sulfonic Acid, although it is known now, there is still a vast world in the future. It is expected to emerge in many fields. Or it can help the research and development of new drugs in the road of medicine, and treat more diseases with its uniqueness. In the chemical industry, or as a key raw material, more exquisite products can be derived. In scientific research and exploration, it can also provide the cornerstone for the construction of new theories. Although the road ahead is long, but with the heart of research and unremitting progress, it will be able to tap more of its potential, shine in the future, bring well-being to the world, and achieve an extraordinary career.

Frequently Asked Questions

What are the main uses of L- (-) Camphor-10-Sulfonic Acid?

L- (−) -camphor-10-sulfonic acid is useful in the field of organic synthesis.
First, in asymmetric synthesis, it is often a chiral adjuvant. It can guide the reaction to a specific chiral direction, resulting in high optical purity of the product. For example, in many nucleophilic addition reactions, L- (−) -camphor-10-sulfonic acid can interact with the reactants with its unique chiral structure. For example, in the alkylation reaction of enolides, it can precisely control the formation of a new chiral central configuration, so that the synthesis of optically active products lays the foundation for the synthesis of single chiral drugs in the pharmaceutical field.
Second, this substance is also often used as a chiral resolution agent. When the racemic mixture is split, the purpose of separation can be achieved according to the difference in physical properties (such as solubility) between the enantiomer and the enantiomer salt formed by L- (−) -camphor-10-sulfonic acid. This process is like a fine screen to precisely separate the enantiomers, which is of great significance in the synthesis of fine chemicals.
Furthermore, in the field of catalysis, L- (−) -camphor-10-sulfonic acid can be used as a catalyst for Bronsted acid. Its acidic properties can effectively catalyze many organic reactions, such as esterification reactions, acetalization reactions, etc. By reducing the activation energy of the reaction, the reaction process is accelerated, and the existence of a chiral environment can also affect the stereochemical results of the reaction, making the catalytic reaction both efficient and highly selective.

What are the physical properties of L- (-) Camphor-10-Sulfonic Acid

L- (−) -camphor-10-sulfonic acid, with unique physical properties. Its shape is a white crystalline powder, which is crystal clear in appearance and delicate in tentacles. It shines shimmeringly in the sun, just like finely crushed silver sand.
This substance is very soluble in water and melts when it enters water, like salt melts in soup, which is instantly shadowless, and the aqueous solution is clear and transparent, like a spring. It also dissolves in alcohols and fuses with alcohols, just like water and milk.
Its melting point is quite clear, about 198 ° C to 200 ° C. When heated up to this point, the substance gradually melts from a solid state, like ice disappearing under the warm sun, and changes from solid to flowing.
Furthermore, optical rotation is its remarkable characteristic. Under certain conditions, its optical rotation is left-handed, like a dancer rotating counterclockwise, with unique optical characteristics, which is of special significance in the field of optics.
In addition, stability is also an important property. Under normal environmental conditions, it can maintain its own structure and properties for a long time, just like it has not changed its quality over time, providing a reliable foundation for many applications, and is indispensable in chemical synthesis, drug development and many other fields.

Is L- (-) Camphor-10-Sulfonic Acid Chemically Stable?

L -( - ) - camphor-10-sulfonic acid is an organic compound with relatively stable chemical properties. Looking at the structure of this compound, the sulfonic acid group has strong polarity and can form hydrogen bonds with many substances, resulting in good solubility in polar solvents. However, its stability does not appear in isolation, but is affected by multiple factors.
From the chemical structure, the rigid structure of the camphor skeleton imparts molecular stability, making it difficult to deform or decompose under normal conditions. Although the sulfonic acid group has high activity, it is connected to the camphor skeleton, and the steric resistance effect makes its reactivity moderated. And the sulfonic acid group can be dissociated under specific conditions to produce stable sulfonate ions, which can also remain stable in aqueous solution.
Temperature has a significant effect on its stability. At moderate temperatures, the compound can maintain a stable state. However, if the temperature is too high, it may initiate decomposition reactions and destroy molecular structures. For example, when the temperature rises to a certain critical value, the sulfonic acid group may be removed, resulting in molecular structure changes.
Furthermore, pH is also a key factor. In an acidic environment, the dissociation of sulfonic acid groups is inhibited, and the molecule is relatively stable; in a strongly alkaline environment, the sulfonic acid group may react with the base, resulting in a decrease in stability. The properties of the
solvent also affect its stability. Polar solvents interact strongly with sulfonic acid groups, which can improve the stability of the compound; non-polar solvents interact weakly with them, or cause their stability to decrease.
In summary, L -( - ) - camphor-10-sulfonic acid is chemically stable under conventional conditions, but its stability may be affected when factors such as temperature, pH value and solvent change.

What should be paid attention to when storing L- (-) Camphor-10-Sulfonic Acid

L- (−) -camphor-10-sulfonic acid is a chemical substance, and many matters need to be paid attention to when storing.
First, when placed in a cool and dry place. This is because the substance is afraid of moisture and moisture. If it is placed in a humid place, it is easy to cause its properties to change, or biochemical reactions, which affect its quality and utility. A cool place can inhibit its chemical changes caused by excessive temperature and maintain its chemical stability.
Second, it needs to be sealed and stored. Because there are many components in the air, such as oxygen, water vapor, carbon dioxide, etc., if the substance is exposed to the air, it is easy to contact and react with these components. Sealing can effectively isolate the air and protect it from external interference.
Third, avoid co-storage with incompatible substances. The interaction between chemical substances is complicated, and L- (−) -camphor-10-sulfonic acid may react violently with certain substances, such as strong oxidants, strong bases, etc. Therefore, its chemical properties must be carefully observed when storing, and it should not be placed in one place with potentially reactive substances to prevent dangerous conditions.
Fourth, the storage place should be away from fire and heat sources. This substance may be flammable or easily decomposed by heat, and the fire and heat sources may cause serious consequences such as combustion and explosion, endangering storage safety.
Fifth, make a good mark. On the storage container, clearly label the name, characteristics, hazards and other information of the substance, which is convenient for access and management, and allows the contact person to quickly understand and take appropriate measures in an emergency.
In short, proper storage of L- (−) -camphor-10-sulfonic acid is related to its quality, safety and subsequent use effectiveness. It should not be taken lightly, and storage specifications must be strictly followed according to its chemical properties.

What are the preparation methods of L- (-) Camphor-10-Sulfonic Acid

For L- (−) -camphor-10-sulfonic acid, there are several ways to prepare it.
First, natural camphor is used as the starting material. Natural camphor is taken from the camphor tree. First, appropriate oxidants, such as chromic acid, are used to oxidize camphor under specific conditions. In a suitable solvent, such as glacial acetic acid, temperature control and time control, so that it can react. Specific parts of camphor are oxidized, and then converted into camphor-10-sulfonic acid. Subsequent separation and purification methods, such as recrystallization, column chromatography, etc., can obtain relatively pure L- (−) -camphor-10-sulfonic acid. This method relies on natural resources, but the amount of natural camphor is limited, and the selectivity and yield of oxidation steps must be carefully considered during the preparation process.
Second, the method of chemical synthesis. Appropriate organic compounds are used as starting materials, such as some terpene compounds. After a multi-step reaction, specific functional groups are introduced first, or through cyclization, oxidation and other reaction steps, a skeleton similar to camphor is constructed. Then, under the action of suitable sulfonating reagents, such as concentrated sulfuric acid and fuming sulfuric acid, sulfonic acid groups are introduced at specific positions. The control of reaction conditions is extremely critical, and temperature, reaction time, and reagent dosage all affect the yield and purity of the product. After synthesis, it also needs to be separated and purified to remove impurities to obtain L- (−) -camphor-10-sulfonic acid.
Third, the method of biocatalysis. Using specific microorganisms or enzymes to catalyze synthesis under mild reaction conditions. Enzymes in some microorganisms have special catalytic activity, which can selectively catalyze the conversion of specific substrates to L- (−) -camphor-10-sulfonic acid. The reaction conditions are mild, the selectivity is high, and the environmental pollution is small. However, screening suitable microorganisms or enzymes is time-consuming and laborious, and the stability and activity of the biocatalyst need to be carefully regulated. Optimization of the fermentation process is also key, which is related to the yield and quality of the product.