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What is the chemical structure of methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzenesulfonate?
I am looking at your words, and I am inquiring about the chemical structure of methyl (S) -2-hydroxy-3- ((S) -2-oxypyrrolidine-3-yl) butyrate 4-methylbenzenesulfonate. This is a difficult problem in the field of organic chemistry, let me go through it in detail.
Methyl itself is a group composed of one carbon and three hydrogens, expressed as "-CH". (S) -2-hydroxy, which means that this compound has a hydroxyl group (-OH) at position 2, and its three-dimensional configuration is (S) type. This three-dimensional configuration is determined according to the Cahn-Ingold-Prelog rule, depending on factors such as atomic number.
3- ((S) -2-oxypyrrolidine-3-yl) moiety, pyrrolidine is a five-membered cyclic structure containing a nitrogen atom. 2-Oxygen represents a carbonyl group (C = O) at position 2 of pyrrolidine, while the (S) type stereo configuration shows its spatial arrangement. This pyrrolidine group is connected to position 3 of the main chain.
In the case of butyrate, the carboxyl group (-COOH) of butyric acid is esterified with alcohol to form an ester group (-COO-). In this structure, the hydrocarbon group of the butyric acid part is connected to the above-mentioned hydroxyl group and pyrrolidine group, and forms an ester group structure.
As for 4-methylbenzene sulfonate, the benzene sulfonate radical group (-SO
) is connected to 4-methylbenzene, and there is a methyl substitution at position 4 of 4-methylbenzene, that is, the benzene ring. The benzene sulfonate moiety is often combined with cations to balance charges, in this case, or with the cationic moiety of the above ester-containing structure.
Overall, this compound has a complex structure, fusing multiple functional groups and specific stereoconfigurations. A affects the properties of molecules based on different positions. Hydroxyl, carbonyl, ester, pyrrolidinyl, and benzene sulfonate can each develop their own capabilities to jointly construct this unique chemical structure, which makes it suitable for organic synthesis, medicinal chemistry, and other fields or has specific uses and properties.
What are the main uses of methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate?
The author of "Tiangong Kaiwu" is a novel of science and technology in ancient China. Its style of writing is simple and profound. Today there is a question: "What are the main uses of methyl (S) -2 -hydroxy-3- (S) -2 -oxo cyclopentyl-3-yl) butyrate benzyl 4-methylbenzenesulfonic anhydride?", and listen to me in detail.
Methyl (S) -2 -hydroxy-3- (S) -2 -oxo cyclopentyl-3-yl) butyrate benzyl 4-methylbenzenesulfonic anhydride is widely used in the field of medicine and chemical industry. In the pharmaceutical industry, it is often a key intermediate. Due to the delicacy of organic synthesis, complex drug molecular structures need to be built based on this substance. For example, the synthesis of some targeted anti-cancer drugs often uses their unique chemical structures to introduce specific functional groups, so that drug molecules can precisely act on cancer cell targets, improve efficacy and reduce side effects.
In the field of materials science, it also has its uses. In the research and development of new polymer materials, it can be used as an initiator or modifier for polymerization reactions. Using this substance to participate in the reaction can regulate the properties of polymer materials, such as improving the mechanical strength, thermal stability and chemical stability of the material. Make the material more suitable for aerospace, electronic devices and other fields with strict performance requirements.
Furthermore, in the manufacture of fine chemical products, such as fragrances, cosmetic additives, etc., it is also indispensable. Due to its unique chemical properties, it can give products a unique aroma or improve the physical characteristics of products, and enhance product quality and market competitiveness.
All of these show that the important use of methyl (S) -2 -hydroxy-3- (S) -2 -oxycyclopentyl-3-yl) butyric acid benzyl 4 -methylbenzenesulfonic anhydride in the chemical industry is a key factor in promoting industrial development.
What is the synthesis method of methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate?
To prepare methyl (S) -2-hydroxy-3- ((S) -2-oxypyrrolidine-3-yl) benzyl butyrate 4-methylbenzenesulfonate, the following method can be used:
Take (S) -2-hydroxy-3- ((S) -2-oxypyrrolidine-3-yl) butyric acid as the starting material, and esterify it with appropriate benzyl alcohol under the action of condensation reagents. Commonly used condensation reagents, such as dicyclohexyl carbodiimide (DCC) and 4-dimethylaminopyridine (DMAP), under this reaction condition, the two can be condensed to generate (S) -2-hydroxy-3- ((S) -2-oxypyrrolidine-3-yl) benzyl butyrate.
Subsequently, the resulting (S) -2-hydroxy-3- ((S) -2-oxypyrrolidine-3-yl) butyrate benzyl ester is reacted with p-toluenesulfonyl chloride in the presence of a base. The base can be selected as an organic base such as triethylamine. During this reaction, the sulfonyl group of p-toluenesulfonyl chloride will replace the hydrogen atom of the alcohol hydroxyl group, thereby generating the target product methyl (S) -2-hydroxy-3- ((S) -2-oxypyrrolidine-3-yl) benzyl butyrate 4-methylbenzenesulfonate.
The reaction process should pay attention to the control of reaction temperature, proportion of reactants and reaction time. The esterification reaction temperature should be maintained in a moderate range, generally between room temperature and 50 degrees Celsius. If the temperature is too high, side reactions may occur, which will affect the purity and yield of the product. During the p-toluene sulfonylation reaction, the amount of alkali should be precisely controlled. If the amount is too small, the reaction may be incomplete, the amount is too large, or other side reactions may be triggered. And the reaction process needs to be carried out in an anhydrous environment to avoid hydrolysis of p-toluenesulfonyl chloride and affect the reaction process. In this way, through this series of steps, the desired product can be obtained.
What are the purity requirements for methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate?
"Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty, but it does not specify the purity requirements of "methyl (S) -2 -hydroxy-3- (S) -2 -oxo, pyrrole, alkane-3 -yl) propionate benzyl 4 -methylbenzene, sulfonate". These chemical substances are the products of fine synthesis of modern chemistry, and their purity requirements vary with the use.
If used in the field of medicine, it is related to the health and safety of patients, and the purity requirements are extremely strict. Pharmaceutical active ingredients need to be highly pure, and the impurity content must be extremely low to prevent impurities from causing adverse reactions. Generally speaking, the purity often needs to reach more than 99% or even higher to meet the medicinal standards.
Used in the field of materials science, if used as a synthetic raw material for special functional materials, it depends on the material performance requirements. If the material needs to have high stability and uniformity, the purity requirements are also high; if the effect on performance is small, the purity requirements may be appropriately relaxed.
Used in general chemical research, to explore the reaction mechanism, verify the theory, etc., the purity requirements are relatively flexible and can be adjusted according to the experimental purpose and method, or 95% or even lower purity can also meet the preliminary research needs.
In summary, the purity requirements for "methyl (S) -2 -hydroxy-3- (S) -2 -oxo, pyrrole, alkane-3 -yl) propionate benzyl 4 -methylbenzene, sulfonate" vary from application scenario to application scenario, and it is difficult to generalize, and it needs to be precisely defined according to the specific application.
What are the precautions for the storage and transportation of methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate?
When storing and transporting methyl (S) -2 -hydroxy-3- (S) -2 -oxypyrrolidine-3-yl) propionic acid 4 -methylbenzenesulfonamide, there are several ends that should be paid attention to.
First, looking at its chemical properties, this substance contains active groups such as hydroxyl groups and oxygenates, which are active or active. When storing, make sure the environment is dry and cool. If it is placed in a humid and warm place, it may cause various reactions such as hydrolysis and oxidation. For example, if the hydroxyl group is easy to interact with the surrounding water vapor, it will cause molecular structure changes, and the efficacy or function will be reduced.
Second, during transportation, it is important to prevent shock and collision. Because of its structure or a certain degree of fragility, violent vibration or collision, or chemical bonds are broken, causing material properties to change. And it needs to be properly separated from other chemicals to prevent mutual reaction. In case of strong oxidizing or reducing agents, or unpredictable changes.
Third, the packaging should be tight. Choose suitable packaging materials to prevent the intrusion of air and water vapor. If an airtight container is used, cover it with a buffer protective material. And on the packaging, clearly mark the material characteristics and warning labels, so that the transportation and storage people can see at a glance and follow the norms.
Fourth, follow relevant regulations and standards. For the storage and transportation of such chemicals, there are national and local customizations. From the setting of storage conditions to the requirements of transportation qualifications, they should be strictly implemented in accordance with regulations to ensure the safety of personnel and the environment. In this way, methyl (S) - 2 - hydroxy - 3 - (S) - 2 - oxypyrrolidine - 3 - yl) propionate 4 - methylbenzenesulfonamide must be properly stored and transported to avoid harm.
What are the chemical properties of Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate?
This is to explore the chemical properties of "Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate". This compound has a unique chemical structure and contains many subtle properties.
From its structural point of view, (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate contains a chiral center, which has a great influence on its interaction and reaction selectivity in vivo. Chirality is like human hands, although similar but cannot overlap. In biochemical reactions, it often fits with specific receptors or enzymes in a unique way, similar to the relationship between keys and locks, and then exhibits special biological activities.
Furthermore, 4-Methylbenzenesulfonate this sulfonate structure endows the compound with certain solubility and stability. Sulfonate structures often have good water solubility, because the sulfonate group can form hydrogen bonds with water molecules, which helps the compound to disperse in polar solvents. And this structure is relatively stable. Under normal conditions, it is not easy to decompose or rearrange spontaneously, which provides convenience for the storage and use of compounds.
From the perspective of chemical activity, amino groups coexist with active groups such as carbonyl groups, so that the compound can participate in a variety of chemical reactions. Amino groups are nucleophilic and can react with electrophilic reagents, such as acyl halides and acid anhydrides, to form amide bonds. This reaction is often used in organic synthesis to construct polypeptides or heterocyclic compounds. The presence of carbonyl also makes the compound can be used as an electrophilic reagent to undergo addition reactions with nucleophiles such as alcohols and amines, further expanding the possibility of its chemical transformation.
In summary, "Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate" has important applications and research values in organic synthesis, medicinal chemistry and other fields due to its unique structure, chiral characteristics, good solubility and diverse chemical reactivity.
What are the common uses of Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate?
Methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate, a specific compound in organic chemistry. Its common uses can be found in the field of organic synthesis.
First, as a key intermediate, it participates in the construction of complex organic molecules. Organic synthesis is like building a delicate castle, and this compound is an important cornerstone. When building natural product analogs with specific biological activities, it can serve as a starting material. Through a series of chemical reactions, such as acylation, alkylation, etc., atoms and functional groups are gradually spliced to shape the complex structure of the target molecule.
Second, it also plays an important role in medicinal chemistry research. The design and synthesis of many drug molecules are often based on this. Due to its structural characteristics, it can impart specific spatial configurations and electronic effects to new drug molecules, which in turn affect the interaction between drugs and targets. Researchers can modify its structure to optimize the activity, selectivity and pharmacokinetic properties of drugs, and strive to develop innovative drugs with better efficacy and fewer side effects.
Third, it also plays a unique role in the field of peptide synthesis. In the preparation of peptide drugs and bioactive molecules, it can be used as a key link in the protection group strategy. By introducing and removing the relevant structures of the compound, the growth and functional group reactivity of the peptide chain are precisely controlled, ensuring the accuracy and efficiency of peptide synthesis, and assisting in the acquisition of high-purity, specific sequence peptide products.
What is the synthesis method of Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate?
The synthesis of methyl (S) -2-amino-3- (S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzenesulfonate is a crucial investigation in the field of chemistry. The synthesis process is complex and delicate, and specific steps and conditions need to be followed.
At the beginning, specific raw materials are often used, or compounds with specific structures are selected. The carefully designed reaction path is used to construct the structure of each part of the target molecule one by one through chemical transformation. Such as using common reactions in organic synthesis, such as nucleophilic substitution reactions, addition reactions, etc. The nucleophilic substitution reaction allows a specific group to replace another group and precisely introduce the desired atom or group into the molecule. The addition reaction can expand the skeleton of the molecule and lay the foundation for subsequent reactions.
During the reaction process, the control of conditions is extremely critical. The temperature will significantly affect the rate and selectivity of the reaction. Moderate temperature can make the reaction proceed efficiently and avoid unnecessary side reactions. Furthermore, the solvent used in the reaction cannot be ignored. Different solvents have an impact on the solubility and reactivity of the reactants. Choosing a suitable solvent can promote the reaction to unfold in a good environment.
Catalysts also play an important role in synthesis. Appropriate catalysts can reduce the activation energy of the reaction, speed up the reaction rate, and enable the originally difficult reaction to proceed smoothly. And the type and dosage of catalysts need to be carefully considered and optimized to achieve the best reaction effect.
Synthesis of methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate requires comprehensive consideration of many factors such as the selection of raw materials, the design of reaction paths, the precise control of reaction conditions, and the rational use of catalysts. After repeated experiments and optimization, a satisfactory synthesis effect can be obtained.
What is the approximate market price for Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate?
This is a question about the market price of (S) -2 -amino-3- (S) -2 -oxypyrrolidine-3-yl) methyl propionate 4-methylbenzene sulfonate. However, I have searched all over the classics, but I have not been able to obtain the exact market price of this product. Due to the fickle market, the price of this compound is determined by many factors, such as raw material cost, difficulty in preparation process, market supply and demand, and pricing varies from supplier to supplier.
If you want to know the exact market price of this compound, you can check it in detail on the chemical trading platform, which gathers quotations from many suppliers and can be compared. You can also consult professional chemical product suppliers, who are familiar with market conditions and can give more accurate price information. Or communicate with industry insiders, who may provide valuable clues based on their experience and industry contacts.
Although I cannot immediately inform you of the exact market price of this compound, following the above channels, a more accurate price may be obtained.
Methyl (S) -2-Amino-3- ((S) -2-Oxopyrrolidin-3-Yl) Propanoate 4-Methylbenzenesulfonate What are the precautions during storage and transportation?
Methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzene sulfonate, a chemical substance, there are many key things to pay attention to when storing and transporting.
First, when storing, be sure to find a cool, dry and well-ventilated place. This chemical substance may be sensitive to humidity and temperature, and high temperature or humid environment is very likely to cause it to deteriorate. If stored in a humid place, water vapor may interact with the substance, causing chemical reactions such as hydrolysis, thereby changing its chemical properties; while in a high temperature environment, the decomposition rate may be accelerated, resulting in the loss of active ingredients.
Second, the integrity of the packaging must be ensured during transportation. The packaging of this substance must be solid and well sealed to prevent leakage. Once leakage occurs, it may not only cause corrosion damage to the transportation equipment, but also pose a threat to the surrounding environment, and may even cause dangerous reactions due to contact with incompatible substances.
Third, it needs to be strictly stored and transported separately from other incompatible substances. Due to the characteristics of its chemical structure, it may react violently with certain substances. For example, avoid co-storage and co-transportation with strong oxidants, strong acids, strong alkalis, etc., otherwise it is very likely to cause serious safety accidents such as fires and explosions.
Fourth, whether it is a storage place or a transportation vehicle, it should be equipped with corresponding emergency treatment equipment and materials. In the event of an unexpected situation such as leakage, effective emergency treatment can be carried out in a timely manner. Such as adsorbents, which can be used to absorb leaking liquids; fire extinguishing equipment to deal with possible fires, etc.
In short, for the storage and transportation of methyl (S) -2-amino-3- ((S) -2-oxypyrrolidine-3-yl) propionate 4-methylbenzenesulfonate, every link needs to be treated with caution, and relevant safety regulations and operating procedures should be strictly followed, so as to ensure the safety of personnel and the stability of materials.