N-[2-({4-[3-(Propan-2-Ylamino)Pyridin-2-Yl]Piperazin-1-Yl}Carbonyl)-1H-Indol-5-Yl]Methanesulfonamide Methanesulfonate (1:1)

This is the nomenclature of an organic compound. To clarify its chemical structure, it is necessary to analyze this nomenclature. This nomenclature follows the nomenclature of organic chemistry and can be obtained by layer-by-layer analysis.
"N - [2 - ({4 - [3 - (Propan - 2 - Ylamino) Pyridin - 2 - Yl] Piperazin - 1 - Yl} Carbonyl) - 1H - Indol - 5 - Yl] Methanesulfonamide Methanesulfonate (1:1) ", which can be separated and analyzed.
"Methanesulfonamide", which is the methane sulfonamide moiety, containing a sulfonyl group (-SO _ 2O NH _ 2O) connected to a methyl group. "Methanesulfonate (1:1) ", refers to methane sulfonate, and binds to the main body in a 1:1 ratio.
"1H - Indol - 5 - Yl", indicating that the 5-position indole ring is involved in bonding, which is a nitrogen-containing heterocyclic structure. " 2 - ({4 - [3 - (Propan - 2 - Ylamino) Pyridin - 2 - Yl] Piperazin - 1 - Yl} Carbonyl) ", where" Piperazin - 1 - Yl "is the 1 position of the piperazine ring," 4 - [3 - (Propan - 2 - Ylamino) Pyridin - 2 - Yl] ", refers to the 4 position of the piperazine ring with 3 - (isopropylamino) pyridine - 2 - group, the 3 position of the pyridine ring is connected to the isopropylamino group, and the 2 position is connected to the piperazine ring. And "2 - ({4 - [3 - (Propan - 2 - Ylamino) Pyridin - 2 - Yl] Piperazin - 1 - Yl} Carbonyl) ", carbonyl (- CO -) connects this complex structure to the 2-position indole ring.
In summary, this compound has an indole ring as the core, a structure containing piperazine, pyridine and isopropylamino at the 2-position, a methanesulfonamide at the 5-position, and a 1:1 ratio of methanesulfonate. After this analysis, its chemical structure can be determined.

The name of this drug is N- [2- ({4- [3- (isopropylamino) pyridine-2-yl] piperazine-1-yl} carbonyl) -1H-indole-5-yl] methanesulfonamide methanesulfonate (1:1), and its pharmacological action is as subtle as "Tiangong Kaiqi".
This drug can act on specific receptors or signaling pathways. Just like the ancient method of refining medicinal pills according to precise proportions, it can precisely bind to targets and regulate intracellular signal transduction, just like following the strict steps of the ancient method to control the reaction and return the disordered physiological process to the right track. In terms of inflammation regulation, it is like the ancient technique of checks and balances, which can inhibit the release of inflammatory mediators, regulate the function of immune cells, and avoid excessive inflammation from causing damage to the body. For some abnormal proliferating cells, it is like the ancient method of restraining evil, which can interfere with the cell cycle, induce apoptosis, and inhibit abnormal proliferation. In neurotransmitter regulation, it is like the clever preparation of fragrances, which can affect the synthesis, release and uptake of neurotransmitters and improve nervous system dysfunction. However, just like the ancient method, there are risks. This drug may have corresponding adverse reactions. When using it, the pros and cons should be carefully weighed like the ancient method to achieve the best therapeutic effect.

N - [2 - ({4 - [3 - (Propan - 2 - Ylamino) Pyridin - 2 - Yl] Piperazin - 1 - Yl} Carbonyl) - 1H - Indol - 5 - Yl] Methanesulfonamide Methanesulfonate (1:1), this is a rather complex organic compound. Its clinical application field is quite extensive, showing unique effects in the treatment of many medical diseases.
In the field of tumor treatment, this compound may intervene in key processes such as tumor cell proliferation and migration by virtue of a specific mechanism of action. For example, in the study of some solid tumors, it can precisely act on specific targets in tumor cells, inhibit the abnormal activation of related signaling pathways, and then slow down the tumor growth rate, and even induce tumor cell apoptosis, bringing new therapeutic hope to tumor patients.
In neurological diseases, it may have an impact on the regulation of neurotransmitters. In the nervous system, the balance of neurotransmitters is crucial, and this compound may improve neurological disorders such as depression and anxiety by adjusting the release, uptake or metabolism of specific neurotransmitters.
In the field of cardiovascular diseases, its potential application value can also be seen. It may act on related cells and molecules of the cardiovascular system, regulate vascular tone, inhibit platelet aggregation, etc., and play a positive role in the prevention and treatment of cardiovascular diseases such as hypertension and atherosclerosis.
However, its efficacy and potential side effects need to be carefully weighed during clinical application. It is necessary to conduct rigorous clinical trials to further explore its safety and effectiveness in order to better apply it in clinical practice and benefit patients.

The name of this drug is N- [2- ({4- [3- (isopropylamino) pyridine-2-yl] piperazine-1-yl} carbonyl) -1H-indole-5-yl] methanesulfonamide methanesulfonate (1:1). In the era of Tiangong Kaiwu, there was no such chemical synthetic drug, so it is difficult to describe its side effects in detail in the classical language of the time. However, based on today's medical reasons, such compounds may have the following side effects.
In terms of digestive system, it may disturb the transportation of the spleen and stomach, causing nausea and vomiting. Due to its special chemical structure, the cover affects the normal acceptance, decomposing and transportation of the stomach and intestines after entering the body, so that the essence of water and grain cannot be transferred normally.
Nervous system, or make the spirit restless, causing headache and dizziness. The ingredients of the drug affect the flow of qi and blood in the brain and nerve conduction, causing the loss of nourishment of the clear orifice and the disorder of the spirit.
In the blood system, or injures the blood, affecting the generation and function of blood cells, such as leukopenia, weakening the function of the outside body, and susceptible to external evil. This is because the drug interferes with the hematopoietic microenvironment of the bone marrow, affecting the differentiation and maturation of blood cells.
The immune system may also be affected, or cause immune dysfunction and Drugs affect the activity of immune cells and the secretion of immune factors, so that the body can resist external evils and dysfunction of self-stability. Although there is no accurate expression in the literary words of "Tiangong Kaiwu", the combination of traditional medical thinking and today's pharmacological knowledge can be deduced from its general side effects.

To prepare N- [2- ({4- [3- (isopropylamino) pyridine-2-yl] piperazine-1-yl} carbonyl) -1H-indole-5-yl] methanesulfonamide methanesulfonate (1:1), the process is as follows.
First take appropriate raw materials, take pyridine-2-ylpiperazine as the starting material, in a suitable reaction vessel, add an appropriate amount of solvent, such as dichloromethane, etc., to create a mild reaction environment. Slowly add the reactant containing isopropylamino, control the reaction temperature within a certain range, or between room temperature and moderate temperature, and with the help of a suitable catalyst, make the two condensation reactions occur to generate the isopropylamino-containing pyridine-2-yl piperazine intermediate.
Mix this intermediate with the indole-5-yl-containing reactant, under specific reaction conditions, or add a condensing agent such as carbodiimide reagents to promote the carbonyl linking reaction of the two, and construct a key structural framework. After careful separation and purification, high purity N - [2 - ({4- [3 - (isopropylamino) pyridine - 2 - yl] piperazine - 1 - yl} carbonyl) -1H -indole - 5 - yl] methanesulfonamide was obtained by column chromatography. After that, methanesulfonic acid is added to this product in a ratio of 1:1, and a suitable solvent, such as ethyl acetate, is selected to fully react the two to form the target product N - [2 - ({4- [3- (isopropylamino) pyridine - 2 - yl] piperazine - 1 - yl} carbonyl) -1H - indole - 5 - yl] methanesulfonamide methanesulfonate (1:1). Purification methods such as recrystallization are used again to remove impurities and improve the purity of the product to meet the required Quality Standards. The whole process requires fine control of the reaction conditions, the proportion of raw materials and the operation of each step before the compound can be prepared.