Products

N-(2-Hydroxyethyl)Piperazine-N'(4-Butanesulfonic Acid)

Lingxian Chemical

Specifications

HS Code

101370

Chemical Formula C8H18N2O4S
Molar Mass 238.305 g/mol
Appearance White to off - white powder
Solubility In Water Highly soluble
Ph Range For Buffering 6.8 - 8.2
Pka Value 7.5 (at 25°C)
Melting Point 234 - 238°C
Stability Stable under normal conditions
Packing & Storage
Packing 500g of N-(2 -Hydroxyethyl)Piperazine - N'(4 - Butanesulfonic Acid) in resealable bags.
Storage N-(2 - Hydroxyethyl)Piperazine-N'(4 - Butanesulfonic Acid), often abbreviated as HEPES, should be stored in a cool, dry place, away from heat sources and direct sunlight. It is best kept in a tightly - sealed container to prevent moisture absorption and contamination. Ideal storage temperature is around 2 - 8 °C for long - term stability, ensuring its quality for various laboratory and industrial applications.
Shipping *N-(2 - Hydroxyethyl)Piperazine-N'(4 - Butanesulfonic Acid)* is shipped in sealed, corrosion - resistant containers compliant with chemical transport regulations. Packaging is designed to prevent spills and ensure safe transit.
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N-(2-Hydroxyethyl)Piperazine-N'(4-Butanesulfonic Acid)
General Information
Historical Development
N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) is actually a product of exquisite chemical industry. Looking back at its past, at the beginning, the academic community was exploring compounds, and occasionally obtained this unique structure. At that time, although its potential was not well understood, those who were keen felt that it was extraordinary.
With the passage of time, science and technology have gradually developed, and all kinds of experiments have come one after another. Scientists have made great efforts to analyze its characteristics, and have found that it is effective in the field of biochemistry. It can stabilize the acid and base of the solution and help many reactions go smoothly. Due to this, its use has become increasingly widespread, and it has gradually entered the realm of industrial production from the laboratory to the field of medicine and biological research.
Product Overview
There is now a substance called N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid). This substance is a chemical product and is quite useful in the field of scientific research. Its properties are stable, and it can play a unique role in a specific environment.
Looking at its structure, it is derived from piperazine. The groups of hydroxyethyl and butanesulfonic acid give it unique characteristics. In biochemical experiments, it can be used as a buffer to maintain the acid-base balance of the system and make the reaction proceed stably.
When preparing this compound, fine operation, temperature control and time control are required to obtain high-purity products. And because of its special nature, storage also needs to be paid attention to to avoid moisture and light to prevent deterioration. When using it, researchers must carefully investigate its properties and use it rationally in order to perform its function and help the progress of scientific research.
Physical & Chemical Properties
The physicochemical properties of N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) are quite critical. This material may be a white crystalline powder with good solubility and easy solubility in water, which is one of its major characteristics. Its melting point and boiling point also have specific values. The melting point is about a certain range, and the boiling point varies according to conditions.
From the perspective of chemical properties, its molecular structure contains specific functional groups, causing it to have certain chemical activity. It can participate in specific chemical reactions and react with other substances under suitable conditions. Due to its stable structure, it is difficult to decompose in general environments, making it widely used in many chemical experiments and industrial production. It is of great significance to research and practice in many fields.
Technical Specifications & Labeling
Today, there is a product called N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid). In the field of my chemical research, its technical specifications and identification (product parameters) are crucial. The technical specifications of this substance are related to the preparation method, from the selection of raw materials, the precision of the ratio, to the temperature and time of the reaction, all need to be precisely controlled, and there must be no mistakes. Its identification (product parameters), such as purity geometry, and properties, are the keys to judging quality. When preparing, follow ancient methods and incorporate new technologies, and strive to meet high standards of products. A clear logo allows users to understand its characteristics and make good use of it. It is beneficial to scientific research and ensures that it is useful in various fields and lives up to its research and development intentions.
Preparation Method
The method of preparing N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) is related to the raw materials and production process, reaction steps and catalytic mechanism. First, an appropriate amount of piperazine is taken, based on it, and 2-chloroethanol is mixed. The two are substituted according to a specific amount at a suitable temperature and pressure. This step requires precise temperature control to avoid side reactions. After the reaction is completed, an intermediate product is obtained.
Then, the intermediate product is mixed with 1,4-butanesulfonolactone to adjust the reaction environment so that the two can react again. In this process, the catalytic mechanism is key, and a specific catalyst can be added to promote the reaction speed and increase the yield. At the same time, the reaction process is closely monitored and the conditions are adjusted in a timely manner. After several refining methods, the impurity is removed and purified, and the pure N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) product is finally obtained, and its quality and quantity are in line with expectations.
Chemical Reactions & Modifications
The reaction and modification of N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) is really the key to chemical research. Its chemical reaction also requires detailed consideration of all factors, such as temperature, pressure, and catalysts. The level of temperature is related to the speed and direction of the reaction. Overheating may cause side reactions to clump, and undercooling may delay the reaction. The change of pressure cannot be ignored, and pressure can promote the progress of the reaction.
As for modification, if you want to achieve its good, you can start from the adjustment of molecular structure. Increase a certain group or change its chain length to change its properties. If it has better solubility and stability, it will be beneficial in all fields. For chemical workers, we should study it carefully and make every effort to improve its application and modification techniques, so that this substance can have better effects in the industry and benefit the world.
Synonyms & Product Names
Nowadays, there is a thing called N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid), which is quite important in chemical products. The nickname and trade name of this thing also need to be carefully examined. Its nickname can be regarded as a name related to its nature or structure, and the trade name is related to the market situation.
In the process of research, scholars need to clarify its namesake and city name. The namesake helps academic communication, so that everyone knows what it is; the market name involves industrial application, which is convenient for product identification. The two complement each other and are the key to studying this thing.
Although it is only about 200 words, the namesake and trade name of N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) have been briefly described. I hope researchers will pay more attention to the two when exploring, so as to clarify the whole picture of this thing in academia and industry.
Safety & Operational Standards
Nowadays, there is a product called N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid), which is very important in the field of my chemical research. The safety and operating standards of this product are of paramount importance and cannot be careless.
When using this product, the first priority is to ensure the safety of the environment. It must be placed in a well-ventilated place to prevent the accumulation of harmful gases and damage to people's health. And the surrounding should be protected from fire and heat sources, because it may be dangerous to explode.
When operating, all utensils must be clean and dry. When using, the method should be stable and accurate, and the amount should be carried out according to the quantity. Do not waste, and prevent overflow. If you accidentally touch the skin, rinse it with plenty of water as soon as possible. If you feel unwell, seek medical attention immediately. If it enters the eye, use water as a buffer as soon as possible, and then rush to the medical office.
There are also rules for storing this thing. It should be stored in a cool, dry and well-ventilated place, away from strong oxidants, strong alkalis and other substances to prevent reactions from changing. Packaging must be tight to avoid contact with air, moisture, etc., resulting in quality changes.
When handling, be careful to prevent damage to the container. In case of leakage, cut off the fire source first and evacuate everyone quickly. Small leaks can be adsorbed by sand, vermiculite, etc., and properly collected and disposed of. A large number of leaks require embankment containment and then professional decontamination.
In short, although N- (2-hydroxyethyl) piperazine-N '- (4-butane sulfonic acid) is a weapon for scientific research, its safety and operating standards need to be kept in mind at all times, and we must not slack off to ensure that everything goes smoothly and is harmless.
Application Area
Today, there is a product called N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid), which has wonderful uses in many fields. In the context of biochemical experiments, it is often used as a buffer reagent, which can stabilize the acid and base of the solution, ensure the stability of the reaction, and enable all biochemical reactions to proceed smoothly. In the process of pharmaceutical research and development, it can regulate the drug microenvironment, help the efficacy of the drug, or increase the stability of the drug, or promote the absorption of the drug. In the field of chemical production, it can also improve product performance and optimize the production process. The application of this substance is like a boat in a river, providing assistance for the progress of various fields. It is an indispensable material.
Research & Development
I have been studying N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) for a long time. This compound is stable and has a wide range of uses in biochemical research. At the beginning, it depends on complicated methods, time-consuming and laborious, and the yield is not high.
My colleagues and I have worked hard to explore new ways and optimize. After months of research, trying different conditions, adjusting the proportion of reactants, and changing the reaction process. Fortunately, the optimization method has improved the yield and quality.
Looking at this achievement, it can be applied in more fields. In the future, we should continue to cultivate and expand its use, with the hope of contributing to the biochemical industry and promoting its development, so that this compound can develop greater capabilities and create more benefits for the academic community.
Toxicity Research
There is a substance called N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid) that wants to investigate its poison. This is the priority of chemical researchers.
Examine this substance in detail, and test its toxicity according to the rules of ancient law. Watch its contact with other substances, and observe its changes in various environments. Although this substance may be available in industries, medicines, etc., the study of toxicity should not be ignored.
After repeated tests, record its situation in detail. Observe its impact on various objects, how living things are affected. Measure carefully, and dare not make mistakes. Hope for certainty, know the depth of its toxicity, for the safety of later use, provide evidence, so that this thing can be used properly, avoid harm and profit, and be used by the world, without causing disaster.
Future Prospects
The future prospect concerns N- (2-hydroxyethyl) piperazine-N '- (4-butanesulfonic acid). I look at this substance, which has unique properties and a wide range of uses. In the field of biochemical research, it can be used as a buffer to maintain a stable environment and ensure smooth reaction.
Nowadays, technology is new, and the exploration of it does not stop. In the future, it may be possible to optimize the synthesis method, reduce costs and improve yield. On the application, it is expected to expand to emerging fields, such as high-end pharmaceutical research and development, special material preparation. When the time comes, this substance will be able to shine brightly, contribute to the progress of science and technology, the improvement of people's livelihood, and become an important boost for future development. The prospect is bright and promising.
Frequently Asked Questions
What is N- (2-hydroxyethyl) piperazine-N ' (4-butanesulfonic acid)?
Both are organic compounds. N - (2 -furanomethyl) guanidine, which contains a furan ring and a guanidine group in its structure. The furan ring is an aromatic five-membered heterocycle, and the guanidine group is a strong nitrogen-containing basic group. This compound is often used as an intermediate in the field of organic synthesis. Due to its active reactivity of guanidine groups, it can participate in many nucleophilic substitution, condensation and other reactions. It may have potential biological activities in pharmaceutical chemistry, such as antibacterial and antiviral.
And N '- (4-pyridinesulfonyl) urea, the structure contains a pyridine ring and a sulfonylureid. pyridine ring is a six-membered nitrogen-containing heterocycle, which is aromatic and weakly basic. Sulfonylureyl is a structural fragment with special biological activity. In the field of pesticides, this compound is mostly used as a herbicide, which can inhibit the activity of specific enzymes of weeds and hinder their growth; in the field of medicine, some of these structural compounds can be used as hypoglycemic drugs, which regulate blood sugar levels by stimulating pancreatic beta cells to secrete insulin.
Although both are organic compounds, due to structural differences, their physical, chemical properties and application fields are different. N - (2-furanomethyl) guanidine focuses on organic synthesis and potential drug activity development; N '- (4-pyridinesulfonyl) urea plays a role in specific fields of pesticides and medicine.
What are the main uses of N- (2-hydroxyethyl) piperazine-N ' (4-butanesulfonic acid)?
N- (2-hydroxyethyl) piperazine-N '- (4-butylsulfonic acid), namely HEPES, is a crucial reagent in biochemical research. Its main uses are as follows:
First, as a buffer. HEPES has a good buffering ability and can maintain the pH stability of the solution over a wide pH range. In the field of cell culture, cell growth is extremely sensitive to environmental pH. HEPES can ensure the constant pH of the cell culture medium, create a suitable growth environment for cells, avoid damage to cells due to pH fluctuations, and enable normal metabolism and proliferation of cells.
Second, used for biochemical experiments. In the study of biological macromolecules such as proteins and nucleic acids, many reactions require specific pH conditions. HEPES can precisely adjust and maintain the pH of the reaction system to ensure the stability of the structure and function of biological macromolecules, making the experimental results more reliable and accurate. For example, in enzyme activity determination experiments, suitable pH is the key to the best activity of enzymes, and HEPES can provide a stable environment for this.
Third, in the field of drug development. In vitro activity studies and pharmacological experiments of drugs often need to simulate the physiological environment in vivo. HEPES can adjust the pH of the buffer to close to the physiological pH of the human body, which helps to evaluate the stability and activity of drugs in the in vivo environment, providing an important reference for drug development.
Fourth, in molecular biology experiments, such as PCR, nucleic acid electrophoresis, etc., stabilizing the pH environment is indispensable. HEPES can effectively maintain the pH stability of the reaction system or electrophoresis buffer, ensure the smooth progress of nucleic acid amplification and separation, and ensure the reproducibility of experimental results.
What are the precautions for using N- (2-hydroxyethyl) piperazine-N ' (4-butanesulfonic acid)?
During the use of N- (2-furfuryl) piperidine and N ' (4-butyryloxy), the following matters should be paid attention to:
One is related to the physical and chemical properties of the two. Both have specific chemical structures and properties. Before use, be sure to understand their melting point, boiling point, solubility, stability, etc. in detail. Such as solubility, if it needs to be dissolved in a specific solvent for reaction or application, be sure to ensure that the selected solvent is suitable for both to prevent poor dissolution or adverse reactions. And the stability of the two is also very critical. It is necessary to know the stability of the two under different temperature, humidity, light and other conditions, so as to store and use it reasonably, and avoid deterioration due to environmental factors and affect the use effect.
Second, the control of the reaction conditions. If the two are used in chemical reactions, the reaction temperature, pressure, reaction time and the ratio of reactants all have a profound impact on the reaction results. For example, the reaction temperature, too high or too low temperature, may cause abnormal reaction rate, or the formation of by-products. And if the ratio of reactants is improper, it may also lead to incomplete reaction and waste of raw materials. Therefore, before the reaction, it is necessary to accurately determine the best reaction conditions through experiments or reference to relevant literature.
Third, safety protection. Many chemical substances are dangerous, and the two may be irritating or even toxic to the human body. Therefore, during the operation, personal protective measures must be taken, such as wearing suitable protective gloves, protective glasses and gas masks, to prevent contact with the skin, eyes, or inhalation of its volatile gases. At the same time, the operating environment should also be well ventilated to reduce the concentration of harmful gases.
Fourth, storage conditions should not be ignored. Store in a suitable environment according to the characteristics of both. Generally speaking, it should be stored in a cool, dry and well-ventilated place, away from fire, heat and oxidants, etc., to prevent dangerous accidents such as fire and explosion. And it should be stored separately from other chemicals to avoid mutual reaction.
In short, when using N- (2-furfuryl) piperidine and N ' (4-butyryloxy), the above matters should be given high priority to ensure the safety and effectiveness of the use process.
What are the physicochemical properties of N- (2-hydroxyethyl) piperazine-N ' (4-butanesulfonic acid)?
The physicochemical properties of N- (2-furanomethyl) guanidine and N ' (4-pyridine sulfonic acid) are particularly interesting and have research value.
First, N- (2-furanomethyl) guanidine, its appearance is often white to off-white crystalline powder. From the perspective of solubility, this substance exhibits a certain solubility in polar solvents such as water. This is because guanidine is highly hydrophilic and can form hydrogen bonds with water molecules. Although the presence of furan rings has certain hydrophobicity, the whole still makes the compound moderately soluble in water. In terms of melting point, it has a specific melting point value, which is an important physical parameter for identifying the substance, and the melting point is relatively stable, reflecting the characteristics of intermolecular forces.
In terms of chemical properties, guanidine is highly active, and its nitrogen-rich structure makes it easy to participate in many chemical reactions as an electron donor. For example, in nucleophilic substitution reactions, the nitrogen atom of guanidine can attack suitable electrophilic reagents, showing nucleophilicity. At the same time, because the furan ring is an aromatic heterocycle, although its aromaticity is slightly weaker than that of the benzene ring, under certain conditions, electrophilic substitution reactions can occur, and the reaction check point is mostly affected by the electronic effects of the substituents on the ring.
Looking at N ' (4-pyridine sulfonic acid) again, its appearance is mostly colorless to slightly yellow crystals or crystalline powders. In terms of solubility, because the sulfonic acid group is a strong hydrophilic group, the compound has good solubility in water and a certain solubility in some organic solvents. Its melting point is also an important physical property, and the existence of different crystalline forms or impurities may have a slight impact on the melting point.
Chemically speaking, the pyridine ring is a six-membered aromatic heterocycle, which has a certain alkalinity, and the nitrogen atom can accept protons. The strong acidity of the sulfonic acid group makes it able to neutralize with bases, and in organic synthesis, the sulfonic acid group can participate in the reaction as a good leaving group. For example, in some nucleophilic substitution reactions, the sulfonic acid ion can leave smoothly and promote the reaction process. At the same time, the substitution reaction on the pyridine ring is also regulated by the electronic effect of the sulfonic acid group, and the reaction check point and activity are affected by it.
The unique physicochemical properties of these two provide rich possibilities and broad exploration space for the research and application of organic synthesis, medicinal chemistry and other fields.
What is the approximate market price of N- (2-hydroxyethyl) piperazine-N ' (4-butanesulfonic acid)?
The market value of N- (2-cyanoethyl) amine and N ' (4-acetamido) is mostly determined by factors such as factors.
First, the grid wave of raw materials is very important. The raw materials required for the synthesis of N- (2-cyanoethyl) amine and N' (4-acetamido) can all fluctuate in terms of land, harvest, supply and demand. If raw materials are rare, supply is not sufficient, and costs rise, the market of both will also be high.
Second, the cost of manufacturing is also high. If the process requires high cost, high energy consumption or special technology, the cost will increase and the sales price will increase. On the contrary, if the cost is easy and low, there may be a downside to the price.
Third, the market demand is also determined by the factors. If the demand for N - (2-cyanoethyl) amine or N ' (4-acetamido) is strong, and the supply is limited, its price will increase; conversely, the demand is low, the supply is left, and the price may decline.
Fourth, external factors such as big problems and policy laws cannot be ignored. Inflation, rate fluctuations, revenue policies and insurance requirements may all change the cost of production, which will affect the market.
Therefore, in order to know the market value of N - (2-cyanoethyl) amine N ' (4-acetamido), it is necessary to pay close attention to the market value of raw materials, the development of manufacturing, the demand of the market, and the external environment, and it is appropriate to add information to the relevant chemical trading platform, manufacturer or supplier, in order to obtain the quality of the product.