N-(4-(1-Cyanocyclopentyl)Phenyl)-2-((Pyridin-4-Ylmethyl)Amino)Nicotinamide Methanesulfonic Acid

This is a complex organic compound, and in order to know its chemical structure, its naming needs to be analyzed in detail. "N- (4- (1-cyanocyclopentyl) phenyl) -2 - ((pyridine-4-ylmethyl) amino) nicotinamide, methanesulfonic acid".
From the beginning of the naming, "N- (4- (1-cyanocyclopentyl) phenyl) ", this part indicates that a phenyl group is attached to the nitrogen atom, and the 4-position of the phenyl group is connected with 1-cyanocyclopentyl group. The cyanyl group is - C ≡ N, and the cyclopentyl group is a cyclic structure containing five carbon atoms.
"2- ((pyridine-4-ylmethyl) amino) " means that there is a substituent at the No. 2 position, which is composed of a pyridine-4-ylmethyl group connected to an amino group. Pyridine is a nitrogen-containing hexamembered heterocycle, which is connected to a methyl group at the 4-position, and the methyl group is connected to an amino group.
"Niacinamide" is a pyridine-3-formamide structure, which is connected to the above part.
Finally "methanesulfonic acid", that is, CH 🥰 SO 🥰 H, has a specific interaction relationship with the main structure, or forms a salt, or has other interactions.
In general, the structure of this compound is composed of a combination of complex groups of many parts, and each part is connected by specific chemical bonds to form a unique chemical structure. In this way, a general understanding of the chemical structure of this compound can be obtained.

N- (4- (1-cyanocyclopentyl) phenyl) 2- ((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid, which is a rather complex organic compound. Its main uses are extremely extensive and of great significance in the field of pharmaceutical research and development.
Because of its unique chemical structure, it can be used as a potential pharmaceutically active ingredient to fight many diseases. In pharmaceutical chemistry, it is often used to design and synthesize new drugs, or to provide a new way for the treatment of specific diseases.
For example, in cancer research, scientists hope to explore its inhibitory effect on cancer cells through in-depth investigation of this compound. It may be able to specifically act on some key targets of cancer cells, hindering the proliferation and metastasis of cancer cells, and then bring new hope for cancer treatment.
Or in the field of immunomodulation, the compound may have an impact on the immune system, modulating the activity of immune cells, for the treatment of immune-related diseases, such as autoimmune diseases.
Furthermore, in neurological diseases, it may also show unique effects, or help improve the function of nerve cells, providing new ideas for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. In conclusion, N- (4- (1-cyanocyclopentyl) phenyl) -2- ((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid has broad research and application prospects in the field of medicine, and is expected to make important contributions to human health.

This substance is called N- (4- (1-cyanocyclopentyl) phenyl) -2- ((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid. Regarding its safety precautions, the details are as follows:
First of all, at the operation level, this substance is potentially dangerous and must be operated in a well-ventilated place. During operation, the operator should wear protective clothing, carefully selected protective gloves and goggles to avoid direct contact with the skin and eyes. After the operation, be sure to wash your hands and expose your skin. Do not eat, smoke or smoke in the operation place to prevent the substance from being ingested orally.
Secondly, as far as storage is concerned, it should be stored in a cool, dry and ventilated place, away from fire and heat sources. It needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed to prevent dangerous reactions. The storage area should be equipped with suitable materials to contain leaks.
Again, for transportation, make sure that the container is well sealed and loaded before transportation. During transportation, make sure that the container does not leak, collapse, fall, or damage. Do not mix with oxidants, acids, alkalis, etc., and the speed of the vehicle should not be too fast during transportation. Do not forcibly overtake to prevent danger caused by bumps and collisions.
Finally, in the event of a leak, in the event of a small leak, it is necessary to avoid dust, collect it in a dry, clean, covered container with a clean shovel, and transfer it to a safe place; in the event of a large leak, an embankment should be built or a pit should be dug for containment, covered with foam, to reduce vapor disasters. At the same time, quickly evacuate the personnel from the leaked contaminated area to the safe area, isolate and strictly restrict access. Emergency responders need to wear self-contained positive pressure breathing apparatus, wear anti-virus clothing, and approach the source of the leak from the side wind and upper wind to properly handle the leakage situation.

This is N- (4- (1-cyanocyclopentyl) phenyl) -2- (((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid, an organic compound. Its physical properties are crucial and are related to applications in many fields.
When it comes to appearance, it is often white to off-white solid powder at room temperature and pressure. This form is conducive to storage, transportation and subsequent processing. Because the powder is fine and scattered, it increases the contact area with other substances, making it easier to participate in the reaction in chemical reactions and accelerate the process.
Solubility is also a key property. In organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it has good solubility. This property is of great significance in drug research and development. Drugs need to be dissolved with the help of suitable solvents in order to be better absorbed by the human body and exert their medicinal effects. In water, the solubility is relatively limited, which is related to the proportion of hydrophilic and hydrophobic groups in the molecular structure. The hydrophobic part accounts for a large proportion, making it difficult to dissolve in water.
Melting point is an important physical parameter. The melting point of the compound is in a specific temperature range, which can be used for purity identification. If the purity is high, the melting point range is narrow and close to the theoretical value; the presence of impurities will reduce the melting point and widen the range.
In terms of stability, it has certain stability under normal storage conditions. However, in the case of strong acids, strong bases or high temperature environments, the molecular structure may change, triggering decomposition or other chemical reactions. Because it contains functional groups such as cyano and amide groups, these groups have certain reactivity under specific conditions.
In summary, the physical properties of N- (4- (1-cyanocyclopentyl) phenyl) -2- ((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid, such as appearance, solubility, melting point and stability, have far-reaching impact on its application in chemical and pharmaceutical fields. Understanding and mastering these properties can make rational use of this compound and promote the development of related fields.

To prepare N- (4- (1-cyanocyclopentyl) phenyl) -2- ((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid, the method is as follows:
First, the corresponding starting materials need to be prepared, such as benzene derivatives containing cyanocyclopentyl, pyridine-4-ylmethylamine and nicotinamide-related compounds, etc., which are the basis for synthesis.
times, the benzene derivative containing cyanocyclopentyl can be connected to the nicotinamide compound in a condensation reaction or the like under suitable reaction conditions. In this case, specific catalysts, such as some organic bases or metal catalysts, may be required to promote the reaction. At the same time, the temperature, time and solvent selection of the reaction are also crucial. The appropriate temperature, or between tens of degrees Celsius and hundreds of degrees Celsius, depends on the specific reactivity; the time takes hours to several days, depending on the monitoring of the reaction process; the choice of solvent, when it is conducive to the dissolution of raw materials and does not interfere with the reaction, such as common organic solvents dichloromethane, N, N-dimethylformamide, etc.
In addition, pyridine-4-ylmethylamine is introduced into the above reaction products. This step may require a specific reaction path, such as nucleophilic substitution reaction. The reaction conditions also need to be precisely regulated to ensure that the amine group is accurately connected to the target position.
After the construction of the key structure is completed, the methanesulfonic acid group is finally introduced. It can be achieved under mild conditions by reacting with methanesulfonic acid or its active derivatives. This step aims to form the methanesulfonate form of the target product.
During the whole synthesis process, after each step of the reaction, suitable analytical means such as thin-layer chromatography, nuclear magnetic resonance, etc. are required to monitor the reaction process and product purity. If there are impurities, they need to be purified by column chromatography, recrystallization, etc. to obtain high-purity N- (4- (1-cyanocyclopentyl) phenyl) -2- ((pyridine-4-ylmethyl) amino) nicotinamide methanesulfonic acid.