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Sulfonic Acid Series Sulfamic Acid Series Guanidine Series

Sulfonic Acid Series

Sulfamic Acid Series

Guanidine Series

Nintedanib Ethanesulfonate Salt

Specifications

HS Code	314185
Chemical Name	Nintedanib ethanesulfonate salt
Molecular Formula	C31H33N5O4.C2H6O3S
Molecular Weight	657.75 g/mol
Appearance	White to off - white powder
Solubility	Soluble in DMSO, slightly soluble in water
Pka	pKa1 = 4.23, pKa2 = 8.72
Storage Condition	Store at -20°C
Melting Point	127 - 133°C
Cas Number	1035772 - 22 - 0
Drug Class	Multi - tyrosine kinase inhibitor
Targets	VEGFR, PDGFR, FGFR

As an accredited Nintedanib Ethanesulfonate Salt factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	10 - gram vial of Nintedanib Ethanesulfonate Salt in sealed, light - resistant packaging.
Storage	Store Nintedanib Ethanesulfonate Salt in a cool, dry place. Ensure the container is tightly sealed to prevent moisture absorption and contamination. Avoid exposure to light as it may degrade the chemical. Ideal storage conditions typically range from 2 - 8°C in a refrigerator, if possible, to maintain its stability and integrity over time.
Shipping	Nintedanib Ethanesulfonate Salt is shipped in accordance with strict chemical transport regulations. It's packaged securely to prevent any leaks or damage, ensuring safe transit to destinations. Special care is taken regarding handling and storage during shipping.

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Competitive Nintedanib Ethanesulfonate Salt prices that fit your budget—flexible terms and customized quotes for every order.

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General Information

Historical Development

Nintedanib Ethanesulfonate Salt, the genus of medicine. It originated in the research of modern medicine. At that time, physicians were difficult to treat painful lung diseases, so they devoted themselves to new drugs. The researchers worked hard and went through countless trials to get this drug. At first, it was only tried on a small scale to observe its effect and response. Gradually, after large-scale clinical verification, it was proved that it has a good effect on idiopathic pulmonary fibrosis and other diseases. As a result, the reputation of this drug has gradually risen, and it has been valued by the medical community. Since its inception, it has continuously improved the preparation method, improved the quality, and benefited many patients. It has taken a solid step in the treatment of lung diseases and become an important mark in the history of medical development.

Product Overview

"Description of Nintedanib Ethanesulfonate Salt"
Today there is a thing called Nintedanib Ethanesulfonate Salt. It is a wonderful chemical product, which is quite functional in various fields of medicine. This product has unique properties, showing a specific appearance, or a crystalline state, or a different shape.
The preparation method requires exquisite craftsmanship and multiple processes to achieve a pure state. In the reaction kettle, all kinds of raw materials are combined in sequence, temperature control and speed regulation must be precise.
In terms of its effectiveness, it can prevent abnormal cell proliferation and slow down the process of tissue fibrosis in the way of anti-fiber. In the field of pharmaceutical research and development, it is like a shining star, bringing new opportunities for the treatment of many diseases, which is expected to solve the suffering of patients and help them recover.

Physical & Chemical Properties

Nintedanib Ethanesulfonate Salt is also one of the chemical products. Its physical and chemical properties are quite critical. Its shape, or a specific state, or powder or crystal, the color is also characterized. Its solubility varies in various solvents, and the state of dissolution in solvents such as water and alcohol is related to its application. The melting point is also an important property. At a specific temperature, the shape will change, which is especially important for preparation and preservation. And its stability varies in different environments, such as temperature, humidity, and light. Understanding these physical and chemical properties, it is necessary to make good use of this chemical in the fields of pharmaceutical research and development, so as to make it effective and avoid its disadvantages, and to help scientific research and industrial development.

Technical Specifications & Labeling

Today there is Nintedanib Ethanesulfonate Salt, and its technical specifications and identification (product parameters) are the key. Looking at its technical specifications, it is necessary to clarify the purity of its ingredients and the stability of its properties. If the ingredients are pure, the efficacy can be relied on, and if the properties are stable, the storage will be safe. In the label, the product parameters are detailed, from the content standard to the applicable domain, should be clear. In this way, the doctor can use it correctly and the patient can rest assured. In the pharmaceutical industry, strict adherence to technical specifications and labeling standards is the foundation of quality, which is related to the health of patients and cannot be ignored. This is also an important task for our chemical researchers.

Preparation Method

The method of making Nintedanib Ethanesulfonate Salt is crucial to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials needs to be carefully selected, with high purity and adaptability. The production process is rigorous, and all links are interlocked. The reaction steps are integrated from the starting material, and after several conversions, they are carried out according to precise conditions, such as temperature, pressure and time control, which is indispensable. The catalytic mechanism uses a specific catalyst to accelerate the reaction process and improve the yield and purity. In the pretreatment of raw materials, impurities are removed and the activity is improved. During the reaction, the parameters are adjusted in a timely manner to ensure a smooth reaction. After separation and purification, pure Nintedanib Ethanesulfonate Salt is obtained. In this way, high-quality products can be prepared to meet the needs of medicine.

Chemical Reactions & Modifications

Nowadays, there is Nintedanib Ethanesulfonate Salt. In the field of chemistry, its chemical reaction and modification are quite critical. The reaction of this compound is related to many chemical processes. Or under specific conditions, it comes into contact with various reagents, causing wonderful changes. The clutch of its chemical bonds and the rearrangement of atoms are all signs of the reaction.
As for modification, it is designed to optimize its properties. Through chemical means, its molecular structure can be adjusted to obtain better stability, solubility or biological activity. Chemists are doing their best to explore suitable methods to make this compound stand out in the fields of medicine and other fields. Looking at its reaction and modification is like a journey to explore the secrets of chemistry, which is expected to bring opportunities for innovation to related industries.

Synonyms & Product Names

Nintedanib Ethanesulfonate Salt, the synonym and trade name of this product, is what our chemical researchers should investigate in detail. Its synonyms or professional terms describe its chemical structure and characteristics accurately. And the trade name has the meaning of market identification, which is the unique name of the product in the industry.
In our research process, it is crucial to distinguish the two. Synonyms help us understand its chemical essence in depth, analyze its molecular composition and reaction mechanism. Trade names are related to market circulation and product promotion. Although they are all products promoted by different manufacturers, there may be differences in trade names.
We need to carefully sort out the relevant information to explore its exact synonyms, such as a specific chemical name, or another name according to its structural characteristics. For product names, we should also pay attention to the characteristics of each brand to ensure that the research is accurate and effective in chemical research and market applications.

Safety & Operational Standards

"Nintedanib Ethanesulfonate Salt Product Safety and Operation Specifications"
The product of Nintedanib Ethanesulfonate Salt is also a chemical product. Its safety and operation specifications should be carefully observed.
In terms of safety, this chemical may pose a potential hazard. When it comes into contact with the skin, it may cause irritation, such as redness, itching, etc. If it is not carefully entered into the eyes, severe pain will occur, and vision may be damaged. Therefore, when operating, protective gear is indispensable. Special protective clothing, protective gloves, and goggles should be worn to protect the eyes to prevent accidental contact.
As for the operating specifications, the first priority is the suitability of the environment. When in a well-ventilated place, avoid the accumulation of gas to prevent harm to the human body. When weighing, make sure to use precise utensils, take them according to the specified amount, and do not make a slight mistake. And when mixing, when slowly adding, stir evenly, do not be too hasty, resulting in abnormal reaction.
If accidentally spilled, quickly clean with appropriate materials, do not spread. After use, store it properly, put it in a cool and dry place, away from fire sources and incompatible objects. In this way, it is possible to ensure the safety of operation, avoid accidents, and make the best use of this chemical without fear.

Application Area

Nintedanib Ethanesulfonate Salt is also a new drug. Its application field is related to the treatment of various diseases. In the treatment of pulmonary diseases, such as idiopathic pulmonary fibrosis, it can block its progression, slow down the disease of the patient, and prolong its growth. It also involves the domain of tumors and can inhibit the growth and metastasis of tumors. Because it can control the activity of related kinases and cut off the nutrient supply and proliferation signals of tumors. And for some inflammation-related lung diseases, it also has the effect of regulating immunity and reducing inflammation. This drug is gradually becoming more and more important in the medical field, seeking well-being for many patients and developing a broad application scene. It must attract the attention of doctors and researchers to explore more possibilities for application.

Research & Development

In recent years, I have been focusing on Nintedanib Ethanesulfonate Salt in the field of medicine. The potential of this substance in the healing of diseases is worth exploring in depth.
At the beginning, its chemical properties were analyzed to understand the wonder of its structure. Also explore the method of its preparation, strive for the goodness of the process, hope to increase its yield and reduce its cost.
Then, study its pharmacological work. In experiments, observe its impact on cell physiology, observe its effect on disease models. See its possible ability to regulate the body's signaling pathways and hinder the progression of diseases.
However, the road to research and development is full of thorns. Such as the difficulty of controlling stability and the unsolved side effects are all challenges. We have worked tirelessly and searched for many things, hoping to overcome these difficulties.
Today, although some results have been achieved, the road ahead is still far away. Only with a tenacious heart and a diligent attitude, we continue to forge ahead, hoping to benefit patients and contribute to the progress of medicine.

Toxicity Research

In recent years, in the study of various medical substances, there is a substance named Nintedanib Ethanesulfonate Salt, which is special in nature and is of great importance to researchers. We take toxicology research as our service to explore its impact on living beings.
At the beginning, we used various experimental organisms to test, observe the changes in their body shape after ingesting this agent. Or observe their behavior, or test their visceral functions. If you see something, the body is abnormal, the viscera or damage, but there is also a state of tolerance.
The study of toxicology is not done overnight, and it must be carefully investigated, the data will be exhausted, and the results will be analyzed. The toxicity of Nintedanib Ethanesulfonate Salt is expected to be confirmed, and a solid foundation is laid for its safe and effective use, so that this agent can be used in the way of medicine, and the advantages outweigh the disadvantages.

Future Prospects

Today there is a thing called Nintedanib Ethanesulfonate Salt, which has deep potential in the field of medicine. Although its use in the world may be limited, looking at its characteristics and unique mechanism, it has emerged in the research of lung diseases and other diseases.
My generation expects that when the day comes, it will be able to shine. Scientific researchers, unremitting study, analyze its nature, and explore new paths. With time, it may be able to eliminate diseases and diseases for patients, and add well-being to all living beings. Its prospects are broad, like stars waiting to shine, like flowers about to bloom. It can be expected to open up new frontiers in the road of medicine, pave the way for health in future generations, and make great achievements for thousands of autumn and create great careers for thousands of generations.

Where to Buy Nintedanib Ethanesulfonate Salt in China?

As a trusted Nintedanib Ethanesulfonate Salt manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading Nintedanib Ethanesulfonate Salt supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the indications of Nintedanib Ethanesulfonate Salt?

The indication of Nintedanib + Ethanesulfonate + Salt is related to various symptoms of pulmonary diseases. It is of great use in the treatment of idiopathic pulmonary fibrosis. Idiopathic pulmonary fibrosis is a type of chronic and progressive interstitial lung disease of unknown etiology, in which the lungs gradually fibrosis changes, resulting in impaired respiratory function. Nintedanib ethanesulfonate can delay the progression of this disease and help patients maintain better lung function and quality of life.
Furthermore, in the case of some non-small cell lung cancers, Nintedanib ethanesulfonate may also be suitable. Non-small cell lung cancer is a common type of lung cancer. Nidanib ethanesulfonate can be administered in combination with other anticancer drugs or alone at a specific stage of the disease to control the growth and progression of the tumor, and to seek more vitality and better prognosis for the patient.
In addition, in some rare interstitial lung diseases, clinical research and practice have verified that nidanib ethanesulfonate also has therapeutic effects on some of these diseases, which can relieve the symptoms of patients, improve their lung lesions and overall health. Doctors will accurately determine whether nidanib ethanesulfonate is suitable for the individual according to the patient's specific medical condition, constitution and related examination results, in order to achieve the best therapeutic effect and protect the patient's health.

What are the side effects of Nintedanib Ethanesulfonate Salt?

Nintedanib + Ethanesulfonate + Salt is a medicine used by physicians. Although it has the power to heal diseases, it also has side effects.
bears the brunt of the impact on the gastrointestinal tract. After many patients take this medicine, they often feel nausea, as if there is something surging in the abdomen, and it is difficult to feel comfortable if they want to vomit. What's more, vomiting also occurs from time to time, and the contents of the stomach are poured out, and the body feels weak. And diarrhea is not uncommon, and the stool is thin and the number of times increases, resulting in the body's water grains and essence being difficult to retain, and the righteousness is gradually depleted.
Furthermore, it also affects the function of the liver. Or it can cause abnormal biochemical indicators of the liver, such as elevated transaminase. Liver, the dirty blood storage, the main drain, if the function of the liver is damaged, the flow of qi and blood is abnormal, and various diseases multiply.
Also, this drug may cause changes in the blood system. Platelet count may be abnormal. Platelets are crucial in the process of coagulation. Changes in the number or disorder of the coagulation mechanism can cause skin ecchymosis, petechiae, and severe bleeding of the viscera.
And taking this drug, some patients will also feel tired and weak, slack all over the body, listlessness, and daily labor and activities are affected by it. Because of the effect of the drug, the body's yin, yang, qi and blood are out of balance, and it is difficult to recover righteous qi, so this is the case.
Although nintedanib ethylsulfonate can treat certain diseases, its side effects should not be underestimated. When using drugs, physicians should weigh the advantages and disadvantages and handle them cautiously, so that patients can not only benefit from the drug, but also avoid its harm.

What is the recommended dose of Nintedanib Ethanesulfonate Salt?

What I am asking you is about the recommended dose of "Nintedanib+Ethanesulfonate+Salt". This drug is called nidanib ethanesulfonate, and the recommended dose varies from condition to condition.
In the treatment of idiopathic pulmonary fibrosis, the recommended dose is 150 mg each time, twice a day, with meals. When taking, the whole capsule should be taken with water, not chewed or crushed. The setting of this dose is based on the results of many clinical trials, with the aim of achieving optimal efficacy and keeping side effects within an acceptable range.
In the application of other diseases, such as non-small cell lung cancer, the specific recommended dose may vary depending on the patient's individual condition, combination medication and other factors. Clinicians need to consider the patient's age, physical function, liver and kidney function, and the specific situation of the disease, etc., and carefully determine the appropriate dose. If the patient has doubts about the use of the dose, they should communicate with professional doctors to obtain accurate and safe medication guidance. Do not change the dose at will, so as not to affect the therapeutic effect or cause adverse reactions.

What is the mechanism of action of Nintedanib Ethanesulfonate Salt?

Nintedanib is a small molecule tyrosine kinase inhibitor, and ethanesulfonate salt is its specific salt type. The combination of the two has significant efficacy in the field of medicine. Its mechanism of action is profound and subtle, focusing on the blocking of several key tyrosine kinases.
Tyrosine kinases play a crucial role in cell signaling processes, and many cellular activities such as proliferation, differentiation, and migration are regulated by it. Nintedanib specifically binds to a variety of tyrosine kinases such as platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), and vascular endothelial growth factor receptor (VEGFR).
When Nintedanib binds to these receptors, it can effectively inhibit the autophosphorylation of the receptors, thereby hindering the activation of downstream signaling pathways. It is like cutting off the key chain of cell transmission information, making abnormal cell proliferation and migration signals unable to be transmitted smoothly. Taking pulmonary fibrosis diseases as an example, the excessive proliferation and migration of fibroblasts is a key pathological link. Through the above mechanism of action, Nintedanib can inhibit the abnormal behavior of fibroblasts and slow down the fibrosis process of lung tissue, thus playing a role in alleviating and treating the disease.
In the tumor microenvironment, VEGFR-mediated angiogenesis is of great significance for tumor growth and metastasis. The inhibition of VEGFR by Nintedanib can effectively inhibit tumor angiogenesis, like cutting off the "nutrient supply line" of tumors, making it difficult for tumor cells to obtain sufficient nutrients, thereby inhibiting tumor growth and spread. With such a delicate mechanism of action, this drug has great potential in the treatment of various diseases.

Nintedanib Ethanesulfonate Salt Interacts with Other Drugs

Nitranib ethylsulfonate (Nintedanib+Ethanesulfonate+Salt) may interact with other drugs. This drug is a good drug for the treatment of idiopathic pulmonary fibrosis, but when used in combination with other drugs, it may interact and endanger the disease.
If taken with CYP3A4 strong inhibitors, such as ketoconazole, itraconazole, etc., or cause the blood concentration of nitranib to rise, increasing the risk of adverse reactions, such as hepatotoxicity, gastrointestinal discomfort, etc. The CYP3A4 enzyme is involved in the metabolism of nitranib, and strong inhibitors will hinder this metabolic process.
If used in combination with CYP3A4 strong inducers, such as rifampin, phenytoin sodium, etc., or the blood concentration of nitranib is reduced, its efficacy is reduced. Because it accelerates the metabolism of nintedanib, it is difficult for the drug to reach an effective level in the body.
Other drugs affect the pharmacokinetics of nintedanib, such as proton pump inhibitors (PPIs), or change the pH of the gastrointestinal tract, affecting the absorption of nintedanib. And some anticoagulants, such as warfarin, are used in combination with nintedanib, or increase the risk of bleeding, because nintedanib may affect the clotting function-related pathways.
Therefore, when prescribing nintedanib ethylsulfonate, physicians must consult the patient's medication history in detail, carefully evaluate the interaction with other drugs, and adjust the drug dose or choose alternative drugs according to the specific circumstances of the disease to ensure the safety and efficacy of the drug. If you are sick, you should also follow your doctor's advice. Do not increase or decrease the amount of medication or use other medications on your own. If you have any concerns, communicate with your doctor immediately.