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Phentolamine Methanesulfonate

Specifications

HS Code	269023
Name	Phentolamine Methanesulfonate
Chemical Formula	C17H19N3O·CH4O3S
Molar Mass	399.46 g/mol
Appearance	White to off - white crystalline powder
Solubility	Soluble in water
Ph	5.5 - 7.5 (1% solution in water)
Pka	7.1
Storage Condition	Store in a cool, dry place
Stability	Stable under normal conditions
Cas Number	65-28-1
Melting Point	160 - 165 °C

As an accredited Phentolamine Methanesulfonate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	Phentolamine Methanesulfonate: 10 - gram vial, tightly sealed for chemical integrity.
Storage	Phentolamine Methanesulfonate should be stored in a cool, dry place away from heat and direct sunlight. It should be kept in a tightly - sealed container to prevent moisture absorption and contamination. Store at a controlled room temperature, typically around 15 - 30°C. Avoid storing near incompatible substances. This ensures its stability and potency over time.
Shipping	Phentolamine Methanesulfonate is shipped with strict compliance to chemical transport regulations. It's securely packaged to prevent leakage, with proper labeling, and transported by means suitable for handling hazardous chemicals, ensuring safety.

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General Information

Historical Development

"The Evolution of Phentolamine Methanesulfonate"
Phentolamine methanesulfonate is a good product in medicine. Its origin was first explored by physicians, hoping to obtain a cure for diseases. In the past, the disease was disturbing, and the medical community searched hard for a good solution.
There were wise people who began to study pharmacology and gradually discovered the wonders of phentolamine. However, at that time it was difficult to extract, and the purity was not perfect.
The years have passed, and the researchers have been unremitting. After many trials, the process has been improved, and its quality has improved day by day. Since the beginning of the beginning, it has become a commonly used medicine, and it has gone through generations of hard work. Today's phentolamine methanesulfonate is very effective in clinical practice. It is a powerful tool for treating diseases and diseases, and it is actually the fruit of the evolution of medicine.

Product Overview

Phentolamine Methanesulfonate is a unique compound. Its unique nature is of great value in the field of medicine. This product has a specific appearance, or is in the shape of a powder, with uniform color and quality. Its structure is exquisite and contains a unique chemical conformation, which makes it have specific physical and chemical properties.
In terms of pharmacological action, Phentolamine Methanesulfonate can cause specific physiological effects in the body. It can act on specific targets and affect related physiological mechanisms. And during the research and development process, it has been tested and verified many times to achieve the best effect and safety. However, its application also needs to be cautious to avoid possible adverse reactions. Exploring this compound may open up new avenues for medical progress and be helpful in the treatment of diseases, which is worth further study.

Physical & Chemical Properties

The style of "Mengxi Bi Tan" records the physicochemical properties of things in classical Chinese, and the physicochemical properties of Phentolamine Methanesulfonate are recorded in today's imitation.
Phentolamine Methanesulfonate, white in color and pure in quality, often in the state of powder. Its properties are stable, and it can survive for a long time at room temperature without change. It is easily soluble in water, melts when it enters water, and dissolves into a clear liquid without impurities. When heated, it changes when it reaches a specific temperature. If it does not reach this temperature, it is as safe as a rock. Mixed with other substances, when it encounters acid and alkali, the reaction varies. According to its chemical properties, it may combine or decompose. Its physical state and chemical properties are all important to those who study this thing, which is related to its wide and narrow use, and is also the basis for making and using this thing.

Technical Specifications & Labeling

"Technical Specifications and Labeling (Product Parameters) of Phentolamine Methanesulfonate"
Fuphentolamine Methanesulfonate is an important product in the field of medicine. Its technical specifications are related to quality and are also the basis for utility. In terms of purity, it needs to be extremely accurate, and the impurity content must be minimal to ensure the stability of the drug effect.
Looking at its logo, the product parameters should be clear. Its properties may be in the shape of white crystalline powder, and key parameters such as melting point and solubility should be indicated. The melting point can be used as evidence for distinguishing authenticity. If it does not match the established standards, it may be counterfeit. Solubility is also related to its performance in the preparation of the drug. In addition, the packaging label should not be ignored, and the product name, specification, batch number, valid period, etc. should be specified to ensure the safety and accuracy of the medication. In this way, the product can be used in medical applications to play its due effect.

Preparation Method

The method of making Phentolamine Methanesulfonate is essential. The raw materials should be carefully selected, such as selecting good materials to build a large building. Its production and craftsmanship must follow the rules of precision, just like craftsmen.
The reaction steps should be carefully observed. The change of each step is related to the final quality. Like cooking in a tripod, the temperature needs to be properly controlled.
And the catalytic mechanism is also the key. Like a pilot lamp, the reaction is guided on the right track. Good use of catalysis can make the reaction fast and pure.
In the production of this product, the raw materials are coordinated with the production process, the reaction steps are carried out, and the catalytic mechanism is magically used, so that the good products of Phentolamine Methanesulfonate can be obtained to meet all needs and benefit the world.

Chemical Reactions & Modifications

Phentolamine Methanesulfonate is also a chemical product. Its chemical reaction and modification are related to many mechanisms.
At the beginning of the reaction, the reactants come together according to specific chemical laws, and the breaking and recombination of chemical bonds are like variations in the microscopic world. During this time, the distribution of electron clouds changes, and the arrangement and reconstruction of atoms follow the laws of chemistry.
However, this reaction is not achieved overnight, and it is often hindered. The disturbance of impurities and the harsh conditions can cause the reaction to fail to meet expectations. To modify this product, it is necessary to study the molecular structure in detail and gain insight into its activity check point.
Or introduce specific groups to change their physicochemical properties; or adjust the reaction conditions to make the reaction go along the ideal path. After many attempts to optimize the environment, Phentolamine Methanesulfonate has better performance and shows its utility in medicine and other fields.

Synonyms & Product Names

"The same name and trade name of phentolamine methanesulfonate"
Phentolamine methanesulfonate has many names and many other names in the industry. The same name of this thing refers to the same chemical entity, but the title is different. The trade name is the name that the merchant takes for its product, hoping to distinguish it from other things and show its characteristics.
Guanfu phentolamine methanesulfonate, the same name or varies depending on the region and academic tradition, but they all refer to this compound. The trade name carries the vision and product positioning of the merchant, or indicates the difference in purity and efficacy. The use of the same name is mostly found in academic seminars and medical records, and is well known to professionals. The trade name is easier to identify for the market, and to attract the eyes of patients and physicians. Although the two refer to the same thing, they are used in different situations, and together promote the application and development of phentolamine methanesulfonate in the way of medicine.

Safety & Operational Standards

Phentolamine Methanesulfonate is also a product of chemistry, which is related to its safety and operating standards.
Although its properties are fixed, when operating, you must abide by the procedures. When taking it, you must use clean equipment. According to accurate measurements, you must not increase or decrease it wantonly. And the surrounding environment, when avoiding fireworks and dry dust, make sure it is stable and undisturbed.
The method of storage is also important. It should be placed in a cool, dry place, away from heat sources and strong light. Cover this thing from heat, light, or mutation of properties, endangering safety.
As for safety, the first protection. Those who handle this object should use appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent it from touching the skin and eyes. If you accidentally touch it, rinse it with plenty of water as soon as possible, and seek medical attention urgently if necessary.
In addition, the disposal of this object must also be carried out in accordance with regulations. Do not dispose of it at will to prevent defacement of the environment. It must be collected and handled in accordance with specific methods to ensure that it is harmless to the surrounding area.
In short, the safety and operation specifications of Phentolamine Methanesulfonate are all important matters. If you follow it, you can ensure that everything goes smoothly and there is no risk of accidents; if you don't, you can't avoid disaster or disaster. We chemical researchers should always be in awe and adhere to these standards in order to achieve a safe and scientific environment.

Application Area

Phentolamine Methanesulfonate is widely used. In the medical tract, it is often applied to many symptoms. It can be used for the diagnosis and treatment of pheochromocytoma, which can help doctors to distinguish the reality of the disease and explore the hidden details of the tumor. It is also often used to relieve local tissue ischemia caused by noradrenaline leakage, such as saving the skin from danger, restoring its blood vessels and vitality. And in the treatment of shock, it can adjust the relaxation and contraction of blood vessels, restore the smooth flow of qi and blood, and save patients from being endangered. It can also treat male erectile dysfunction, help them regain health and enjoy family happiness. All these uses depend on the power of this medicine, which is important in the medical community and should not be underestimated.

Research & Development

Today there is Phentolamine Methanesulfonate, and we are exploring the path of its research and creation as researchers. In the past, in order to solve many physiological problems, medical researchers worked tirelessly. To observe the mysteries of the sympathetic nerve, I wanted to find a way to regulate it, so I focused on this substance. After years of experiments, its chemical properties and pharmacological mechanisms were carefully observed. At first, the results were not obvious, but the researchers were not discouraged, and they repeatedly deliberated and improved the preparation method. Gradually, it can antagonize sympathetic nerve receptors, and has great potential in cardiovascular, neurological and other fields. Today, the use of this substance in medical research is gradually expanding. We should continue to build on the past, deepen research, and expand its use, with the aim of seeking well-being for human health and promoting the progress and development of scientific research.

Toxicity Research

"On the toxicity of phentolamine methanesulfonate"
Today's research on toxicity, phentolamine methanesulfonate is the most important thing for me to investigate. It may have applications in medical practice, but the investigation of toxicity cannot be ignored.
I observe its nature and test it by various methods. Observe its entry into the body, or cause changes in qi and blood, and respond to the viscera. Although it has the power of healing diseases, the toxicity is hidden in it. Apply it to things, and observe the differences in its life, shape and spirit. Or there is restlessness, or there is a sign of body qi violation.
Signs of toxicity, related to dose and age. Few are hidden but not obvious, and many are all symptoms. And different bodies should be different. Therefore, to study its toxicity, it is necessary to comprehensively examine it, and record all the conditions in detail, so as to clarify its nature and use it for medical reasons.

Future Prospects

Phentolamine Methanesulfonate is useful in the field of medicine. However, looking at its future, it still has a wide range of prospects for expansion.
Today, its treatment for vascular diseases has been effective. However, with the continuous progress of medicine, more difficult diseases, such as some rare circulatory disorders, may emerge in the future. Scientists make unremitting research, hoping to explore more of its hidden pharmacology and explore its applicability.
And the craftsmanship will also become more refined. The higher the purity, the less the side effects. In this way, it can not only increase the healing rate of patients, but also reduce their pain. Therefore, the future of Phentolamine Methanesulfonate is expected to shine brightly in the forest of medicine and add powerful support to the health of all living beings.

Where to Buy Phentolamine Methanesulfonate in China?

As a trusted Phentolamine Methanesulfonate manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading Phentolamine Methanesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main indications of Phentolamine Methanesulfonate?

Phentolamine methanesulfonate is a medicine commonly used by physicians, and its main treatment is quite extensive.
First, it is used for the diagnosis and treatment of pheochromocytoma. People with pheochromocytoma often secrete too much catecholamine, causing blood pressure to rise sharply. Phentolamine methanesulfonate can block alpha receptors, reduce blood pressure, relieve hypertensive crisis caused by excessive catecholamine, and help physicians diagnose this tumor.
Second, it is aimed at refractory congestive heart failure. Heart, such as a pump, when heart failure, pumping blood is weak. This drug can dilate blood vessels, reduce the load before and after the heart, increase cardiac output, improve cardiac function, and relieve asthma, edema and other diseases in patients.
Third, it is also useful in the field of anti-shock. During shock, the whole body has microcirculation disorder and blood vessels constrict. Phentolamine methanesulfonate can dilate blood vessels, improve microcirculation, increase tissue perfusion, provide nutrients and oxygen to the body, and help shock patients recover.
Fourth, it is also effective for male erectile dysfunction. It can relax the smooth muscle of the corpus cavernosum of the penis, increase blood flow to the corpus cavernosum, and make the penis erect, which is difficult for many patients to explain.
When using this medicine, doctors should carefully observe the patient's condition, weigh the pros and cons, and prevent adverse reactions to achieve the best curative effect.

What are the side effects of Phentolamine Methanesulfonate?

Phentolamine methanesulfonate is a medicine commonly used by physicians. Although it is effective in healing diseases, there are also various side effects.
One is related to the vascular system. After taking the drug, it is common to see blood vessels dilate, causing a sudden drop in blood pressure. This can cause dizziness, dizziness, and even fainting. If the patient is already weak, or has low blood pressure, the harm is even worse. The blood pressure drops suddenly, the blood supply to the brain is insufficient, and the spirit is disnourished, so he is dizzy and ready to serve.
Second, the heart is also tired by it. It can cause rapid heartbeat and palpitations. The heart is the official of the monarch, and the gods are absent. The heartbeat is abnormal, and people are panicked and can't sit still. This is because the drug affects the electrophysiological activity of the heart and causes heart rhythm disorder.
Third, it is related to the stomach. It is easy to cause nausea, vomiting, abdominal pain and other diseases. Those with the spleen and stomach are the officials of the warehouse, and the five flavors come out. Drug stimulation, the spleen and stomach are abnormal in transportation, the clear qi does not rise, and the turbid gas does not fall, so they vomit and suffer from abdominal pain.
Fourth, it also affects the nervous system. Or cause the patient to have headache and fatigue. The brain is the sea of marrow, the meeting of all yang. Drug disturbance, the brain is restless, and the yang qi is not vibrating, so the headache and fatigue are weak.
When a doctor uses this drug, when the patient's physical condition is carefully reviewed, the pros and cons are weighed, and the strategy is complete, and it must not be careless.

How to use Phentolamine Methanesulfonate

Phentolamine methanesulfonate is a medicine commonly used by physicians for the treatment of diseases. Its usage varies depending on the disease, and is described as follows:
If used for the diagnosis and treatment of pheochromocytoma, before surgery, it is advisable to do a diagnostic test with phentolamine methanesulfonate. Take 5 mg of this medicine, dilute it with an appropriate amount of water, and slowly inject it intravenously. After injection, closely observe the changes in blood pressure and other signs. In order to relieve the hypertensive crisis caused by pheochromocytoma, 5 mg can also be injected intravenously to quickly lower blood pressure and relieve the patient's urgency.
When used for anti-shock, it aims to improve microcirculation and improve tissue perfusion. Usually 10-20 mg of phentolamine methanesulfonate, added to 500 ml of 5% glucose injection, intravenous drip. During the drip process, close attention should be paid to the patient's blood pressure and heart rate, and the drip rate should be adjusted according to the condition.
In the treatment of heart failure, this drug can reduce the load on the heart before and after. Generally, 10-20 mg of phentolamine methanesulfonate, added to 250-500 ml of 5% glucose injection, is injected intravenously at an appropriate speed to help the heart restore its ability to pump blood.
When using this drug, the doctor must carefully observe the patient's condition and weigh the pros and cons. Because it may cause adverse reactions such as hypotension and tachycardia. When used properly, it can save the patient from the pain. If you are not careful, you may be afraid of other changes. Therefore, when using medication, you must be cautious and always pay attention to the patient's response in order to be safe.

What are the contraindications of Phentolamine Methanesulfonate?

Phentolamine methanesulfonate is contraindicated in the following categories.
Pregnant women should not use it. This drug is used during pregnancy, or there is a potential risk to the fetus. Due to the different physical conditions of pregnant women, fetal development depends on the stability of the mother's environment. After the drug is absorbed by the mother, or through the placental barrier, it affects the fetus, resulting in abnormal development. Therefore, pregnant women must avoid this drug to protect the health of the fetus.
It is also not suitable for breastfeeding women. Drugs are secreted through milk, and when the baby sucks breast milk, or ingests drug ingredients. Infant viscera is delicate, liver and kidney function is not complete, it is difficult to metabolize foreign drugs in time, easy to cause drug accumulation, cause adverse reactions, damage the baby's health, so breastfeeding women should be used with caution.
People with severe arteriosclerosis should not use this drug. Such patients have blood vessel wall elasticity, lumen stenosis, and phentolamine methanesulfonate may affect blood vessel tension, cause hemodynamic changes, or lead to serious complications, such as cerebrovascular accident, myocardial infarction, etc., life-threatening.
Those with a history of gastric ulcer should also be cautious. This drug may affect gastrointestinal peristalsis and gastric acid secretion, and has a stimulating effect on gastric mucosa. People with gastric ulcers, the gastric mucosa is already damaged, the use of this drug, or make the ulcer surface enlarged, aggravated, and even cause serious consequences such as gastric bleeding.
Patients with hypotension are also contraindicated. Phentolamine methanesulfonate has the effect of lowering blood pressure. If used in people with hypotension, the blood pressure may drop even lower, causing insufficient blood supply to the brain, heart, kidney and other important organs, causing dizziness, palpitations, oliguria and other symptoms, and in severe cases, shock.

Phentolamine Methanesulfonate Interacts with Other Drugs

Phentolamine Methanesulfonate is a commonly used drug and has many clinical applications. Its interaction with other drugs is crucial, which is related to the safety and efficacy of the drug.
In terms of its interaction with cardiovascular drugs, if it is used in combination with antihypertensive drugs, or the antihypertensive effect is enhanced, blood pressure will drop excessively, causing dizziness, fatigue, and even fainting and other hypotensive symptoms. Taking nifedipine as an example, when the two are used in combination, the effect of vasodilation is superimposed, and the risk of sudden drop in blood pressure is greatly increased. Therefore, when combined, blood pressure needs to be closely monitored and the dose adjusted in a timely manner.
When used in combination with sympathetic amine drugs such as epinephrine, phentolamine methanesulfonate can antagonize some of its effects. Adrenaline has the ability to raise blood pressure and excite the heart. However, phentolamine mesylate can block the vasoconstrictive effect of adrenaline, weaken the blood pressure-boosting effect, and the interaction between the two on the heart, or increase the probability of arrhythmia.
Furthermore, when combined with digitalis cardiotonic glycosides, phentolamine mesylate can enhance myocardial contractility, and digitalis also has a cardiotonic effect. When used in combination, myocardial contractility is excessively enhanced, cardiac self-discipline changes, and arrhythmia is easily induced. In clinical application, the cardiac condition of patients should be carefully evaluated and ECG monitoring should be strengthened.
In addition, when used with hypoglycemic drugs, phentolamine mesylate may affect blood sugar metabolism and interfere with the efficacy of hypoglycemic drugs. When diabetic patients use these two types of drugs, they need to closely monitor blood sugar levels and adjust the dose of hypoglycemic drugs in time to prevent blood sugar fluctuations.
In short, phentolamine mesylate interacts with many drugs. When using clinical drugs, doctors must carefully observe the patient's medication history, weigh the pros and cons, choose drugs reasonably, adjust the dose accurately, and closely monitor the patient's response to ensure the safety and effectiveness of the medication.