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What is the main function of Phentolaminemethanesulphonate?
Phentolamine mesylate, its main functions are as follows:
This drug has the ability to dilate blood vessels, which can reduce peripheral vascular resistance. This is because it can block alpha receptors, which can relax vascular smooth muscles and dilate blood vessels. In clinical practice, it is often used to treat peripheral vasospastic diseases, such as Raynaud's disease, which can dilate spastic blood vessels and relieve limb ischemia.
Furthermore, phentolamine mesylate is quite beneficial for improving microcirculation. In shock treatment, timely application of this drug can dilate small arteries and veins, increase blood flow velocity, improve tissue blood perfusion, improve microcirculation disorders, and help shock patients relieve the condition.
At the same time, it can also antagonize the vasoconstriction caused by the leakage of noradrenaline. If noradrenaline is leaked intravenously, it can cause strong local vasoconstriction, causing tissue ischemia and necrosis, and local infiltration injection of phentolamine methanesulfonate can resist this kind of vasoconstriction and prevent tissue necrosis.
In addition, this drug also plays an important role in the diagnosis and treatment of pheochromocytoma. It can be used to diagnose pheochromocytoma, through its impact on blood pressure, etc., to assist in judging whether you have this tumor; when used before surgery, it can effectively control blood pressure and reduce the risk of surgery.
What are the side effects of Phentolaminemethanesulphonate?
Phentolamine methanesulfonate is a medicine commonly used by doctors, but it also has various side effects, which cannot be ignored.
First, it is related to the cardiovascular system. Those who use this drug have common symptoms of hypotension. After the drug is introduced into the body, it quickly relaxes the smooth muscles of the blood vessels, causing vasodilation and a sudden drop in blood pressure. Patients often feel dizzy, even faint, walk like cotton wool, and stand unsteadily. It can also cause tachycardia, palpitations, and the heart is like a deer ramming, and the rhythm is disordered. This is all because after the blood pressure drops, the body is underreplenished, the sympathetic nerves are excited, and the heart compensates for accelerated beating.
Second, it also affects the gastrointestinal tract. Many users find gastrointestinal discomfort, such as nausea and vomiting, something in the abdomen seems to be stirring, and the stomach qi is reversed. Sometimes it looks like vomiting, and it is difficult to stay when eating. And it can cause abdominal pain, pain or dull pain, or twisting like thorns. It can also cause diarrhea, rapid peristalsis of the intestines, frequent defecation, loose stools, several times a day, resulting in weakness.
Third, the nervous system is also affected. Some patients feel headache, if the head is pressed by heavy objects, or seems to have needle prickling pain. And it is easy to cause hypersensitivity, difficulty sleeping, tossing and turning at night, thoughts flying, disturbing normal work and rest. Or present restlessness, temperament mutation, irritability for no reason, affecting daily getting along with people.
Fourth, it has occasional effects on the respiratory system. After a few people take the drug, they have shortness of breath, poor breath, need to gasp for breath, seem to be insufficient to use, and the throat may feel tight, which can cause breathing difficulties and endanger life in severe cases.
Therefore, when doctors use phentolamine mesylate, they must carefully observe the symptoms of the patient, weigh the pros and cons, and be cautious to prevent side effects from causing pain to the patient and damaging their health.
What are the applicable groups of Phentolaminemethanesulphonate?
Phentolamine methanesulfonate is suitable for a wide range of people. Among men, this medicine may help if they are not erectile or impotent. Because this medicine can dilate the blood vessels of the corpus cavernosum of the penis, increase blood perfusion, and improve erectile function.
It may also be suitable for women who have cold sex and lack of eroticism. It can regulate blood circulation in the reproductive system, stimulate women's sexual impulses, and enhance the pleasure of the boudoir.
Furthermore, before surgery, in order to prevent patients with sudden rise in blood pressure and tachycardia caused by emotional stress, phentolamine methanesulfonate can be used for prevention. Because it can soothe vascular smooth muscles, calm blood pressure, and stabilize the heartbeat to ensure smooth surgery.
In addition, for patients with pheochromocytoma, this drug is also a good agent. The tumor often causes a large amount of catecholamine release, causing a sharp increase in blood pressure. Phentolamine mesylate can antagonize the effect of catecholamine, effectively control blood pressure, and relieve related discomfort symptoms.
Of course, it is necessary to be clear that the medication must be followed by the doctor's advice, and no unauthorized advice should be made, so as to avoid the wrong medicine and reproduce the scourge.
Phentolaminemethanesulphonate how to use
Phentolamine methanesulfonate is a drug, and its use should be carefully followed. This drug can be administered by intravenous injection, intravenous drip, etc.
If intravenous injection is performed, an appropriate amount of phentolamine methanesulfonate should generally be diluted with an appropriate amount of injection water or normal saline, and then slowly injected into the vein. The injection process must pay attention to the patient's reaction, such as changes in blood pressure and heart rate. The injection speed should not be too fast to prevent adverse reactions such as hypotension.
If intravenous drip is used, phentolamine methanesulfonate should be added to the appropriate infusion solution according to the specified dose, such as glucose injection or normal saline. After fully mixing, intravenous drip should be carried out at a suitable drip rate. During the drip period, it is also necessary to closely monitor the patient's vital signs, and adjust the drip rate and dosage in a timely manner according to the specific condition of the patient.
When using phentolamine methanesulfonate, it is necessary to strictly follow the doctor's instructions, and do not change the dosage and usage without authorization. And it is necessary to know the patient's medical history, allergy history and other information before medication. For those with severe arteriosclerosis, severe renal insufficiency, gastric ulcer and other diseases, it is especially necessary to use caution. During the medication process, if the patient has uncomfortable symptoms, such as dizziness, palpitations, breathing difficulties, etc., the medication should be stopped immediately and corresponding treatment measures should be taken. In this way, the purpose of safe and effective medication can be achieved.
What are the precautions when using Phentolaminemethanesulphonate?
When using phentolamine methanesulfonate, you should pay attention to the following things:
First, be sure to check the patient's condition and constitution carefully before taking the medicine. Doctors should carefully investigate the patient's past medical history, such as whether there is a chronic cardiovascular disease, whether the liver and kidney function are healthy and prosperous, and if the liver and kidney function are weakened, the drug metabolism or stagnation may easily lead to the accumulation of drugs and toxins. And those who are allergic to drugs should not use it to prevent allergic crises.
Second, when taking medicine, strictly follow the doctor's instructions and precisely control the amount. The dosage of phentolamine methanesulfonate must depend on the severity of the condition and individual differences of the patient. If the dosage is too large, it may cause hypotension, heart palpitations and other diseases, and even endanger life; if the dosage is too small, it will be difficult to achieve the expected effect. During the course of medication, when the blood pressure, heart rate and other signs are carefully checked, if there is any abnormality, it should be dealt with immediately.
Third, pay attention to drug interactions. When this drug is used in combination with many drugs, it may interact. If taken with antihypertensive drugs, the antihypertensive effect can be superimposed, causing a sudden drop in blood pressure; when used in combination with sympathomimetic amines, it can antagonize its blood pressure-boosting power. Therefore, before medication, patients should inform the doctor of the medicine they are taking in detail in order to weigh the advantages and disadvantages and avoid risks.
Fourth, be vigilant for adverse reactions. After medication, there may be adverse reactions such as hypotension, tachycardia, nasal congestion, and vertigo. If the patient feels unwell, he should inform the doctor immediately. Those with mild symptoms may relieve themselves; those with severe symptoms require immediate treatment.
Fifth, special groups should be especially cautious when using drugs. Pregnant women, breastfeeding women, children and the elderly, the risk of drug use may be higher than ordinary people. Pregnant women and breastfeeding women use drugs, or endanger the health of the fetus and baby; children's organs are not fully developed, and the function of the elderly's organs is gradually declining. Doctors need to weigh the pros and cons and use drugs cautiously.