Products

Piperazine-1,4-Bi[2-Hydroxypropanesulfonic Acid]

Lingxian Chemical

Specifications

HS Code

278553

Chemical Formula C10H22N2O8S2
Molecular Weight 362.42 g/mol
Appearance White to off - white powder
Solubility Soluble in water
Ph Range For Buffer 6.8 - 8.2
Pka Values pKa1 = 6.8, pKa2 = 8.2
Melting Point ~290 - 300 °C (decomposes)
Stability Stable under normal conditions
Density N/A (powder)
Application Used as a buffer in biological and biochemical research
Packing & Storage
Packing 1 kg of Piperazine - 1,4 - Bi[2 - Hydroxypropanesulfonic Acid] packaged in a sealed bag.
Storage Piperazine - 1,4 - Bi[2 - Hydroxypropanesulfonic Acid] should be stored in a cool, dry place. Keep it away from direct sunlight as exposure can potentially degrade the chemical. Store in a well - sealed container to prevent contact with moisture and air. Avoid storing near reactive substances to minimize the risk of unwanted chemical reactions.
Shipping Piperazine - 1,4 - Bi[2 - Hydroxypropanesulfonic Acid] is shipped in well - sealed containers. Special care is taken to prevent exposure to moisture and extreme temperatures during transit to maintain chemical integrity.
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Piperazine-1,4-Bi[2-Hydroxypropanesulfonic Acid]
General Information
Historical Development
Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] is actually a product of chemical industry. Although its origin is difficult to investigate in detail, in the past when chemical technology was evolving, many parties worked hard to achieve this result.
At the beginning, various explorations or only ignorant attempts were made, hoping to find a way between material changes. As the years passed, craftsmen gradually became more accurate in their grasp of various elements and reactions. After countless blending and trials, the properties of this compound became known to the world. It has emerged in many fields, or used for delicate experiments, or devoted to grand industrial processes.
From ancient times to the present, Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] has been advancing along with the chemical industry. In the changing times, it has always been an important role in promoting the development of chemical technology, witnessing the brilliance of chemical history.
Product Overview
Today there is a substance named Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid]. This substance is obtained through careful research. It is unique in nature and has many specific qualities.
Looking at its structure, it is exquisite and orderly, and the molecular arrangement is rigorous, just like a natural workmanship. In various reactions, it can often play a unique role, either as a catalyst or to help the reaction move forward smoothly.
The preparation method also needs to be carefully controlled. The choice of raw materials and the setting of conditions are all related to the quality of the final product. Every step is like a craftsman's carving, and there is no room for any difference.
This product has considerable application prospects in the fields of chemical industry, medicine, etc. It is a rare and delicate product that contributes to the development of scientific research and industry.
Physical & Chemical Properties
Taste of chemical things, its properties are very complex, and it is related to people's livelihood. Today there is Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid], this substance is also. Its physical and chemical properties are worth exploring.
View its shape, or powder, color or white or near nothing, fine and uniform. As for its solubility, in water or in a good state, soluble and fast, like nectar into a spring, blending seamlessly. Its thermal stability is also good, under high temperature, it still retains its quality and does not easily decompose, such as the solid of a rock.
Its chemical activity, in combination with various substances, or new substances, has a specific ability. In the reaction, it can be used as a medium or a key agent to help the reaction go smoothly, such as a tool of good work, which is indispensable. The wonders of the physical and chemical properties of this substance are to be studied in detail by our generation to make the best use of it and benefit the world.
Technical Specifications & Labeling
Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] is also a chemical product. Its technical specifications and identification (product parameters) are related to quality. Looking at its preparation, it is necessary to follow a rigorous method. The choice of raw materials must be pure; the reaction conditions, temperature and humidity, time, etc. must be precisely controlled.
In terms of identification, key parameters such as ingredients and characteristics should be clearly indicated to clarify its quality. Product parameters, such as purity and impurity content, are all accurate measures of quality. In this way, only the best products that meet the specifications can play their due effect in the chemical research and application field, and live up to the efforts of developers and meet the needs of all parties.
Preparation Method
The method of making Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] is the key to the raw materials and production process. First take pure piperazine, with an appropriate amount of propane sulfonic acid raw materials containing hydroxyl groups. The production process, the first step of the reaction. In a special reactor, control the temperature to a suitable range, about one hundred and twenty degrees Celsius, and adjust the pH value in the weakly basic range, so that the two can fully react. This process requires precise control of the reaction time, about three hours. After the reaction is completed, the purification mechanism is carried out. Impurities are adsorbed by ion exchange resin, and then recrystallized to obtain a pure product. In this way, high-quality Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] products are obtained.
Chemical Reactions & Modifications
To taste the wonders of chemistry is related to the change of substances, reaction and modification, which is really the key. In today's words, Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid], the chemical reaction of this substance is like the combination of yin and yang, and the fusion and transformation of various elements. To understand the method of its modification, it is necessary to study the reaction mechanism in detail.
View its reaction, or due to changes in temperature and pressure, the molecular structure is changed. It is like the universe is twisted, the atoms are reorganized, and new substances are produced. Its modification is also aimed at optimizing the performance, or increasing its stability, or strengthening its activity.
If you can accurately grasp the essence of the reaction and properly regulate the conditions, you can make this substance play a perfect effect. In the field of chemical industry, it depends on this for material improvement or drug synergy. Therefore, in the study of chemistry, reactions and modifications must be observed in order to improve the environment and benefit the world.
Synonyms & Product Names
Today there is a thing called Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid]. This substance has a unique function in the field of chemistry. Its namesake and trade name also need to be studied in detail.
The name of a chemical thing is many, and there are many of the same quality, and it is different because of the different uses and systems. Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid], or has a nickname, and this nickname is also related to the trade name. When studying this thing, when studying the references of the same name and the trade name, clarify its source and distinguish its use. In this way, we can know the utility of this product in the chemical industry, medicine and other industries, so as to make good use of it and seek for the prosperity of the industry and the benefit of the people.
Safety & Operational Standards
The industry of chemical industry is related to people's livelihood, and the safety and operation of its products are of the utmost importance. Today there is Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] This product is produced by chemical industry, and its safety and operation regulations must not be ignored.
The safety of this product lies in its purity. Take refined and good materials, follow the method of the right path, so that there is no miscellaneous dross, so that the user can be guaranteed. If the quality is impure, or poisonous and harmful, it will be a disaster to people. Therefore, check its quality, strict and strict, and make sure to meet the standards.
As for the rules of operation, the operator must understand its nature. This object may have a specific nature, and it should be treated with caution in case of heat, moisture, and other objects. When operating, protective gear must be worn, such as clothing, covers, and gloves, to prevent it from hurting the body. And do it in a well-ventilated place to avoid its gas accumulation and prevent accidents.
The method of storage is also essential. It is advisable to keep it in a cool and dry place, away from fire and heat sources. Store it in different categories, and do not mix with other things to prevent phase transformation.
When handling, handle it with care, and do not let it fall. If there is a leak, deal with it quickly according to the prescribed method, and do not let it disperse to avoid harm to the environment.
In short, the safety and operation rules of Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] are related to the well-being of everyone and the prosperity of the industry. All the public are in the industry, and they must be trembling to be right. Keep the safety rules and keep them safe.
Application Area
Since modern times, the technology of chemistry has advanced day by day, and various new substances have emerged. Today there is Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid], which has a wide range of application fields. In the field of medicine, it can help stabilize the drug, increase its efficacy, or help the diagnosis and treatment of diseases. In chemical production, it can regulate the reaction process, make the product pure, and optimize the process. In material science, it can endow material-specific properties, such as enhancing its stability and hydrophilicity. And it can also be used in biochemical research, assisting in the analysis of biomolecular mechanisms, and exploring the mysteries of life. These applications all show their extraordinary value, contributing to the development of various fields, promoting the progress of science and technology, and benefiting the world.
Research & Development
In modern times, chemistry has flourished, and all kinds of substances are of great importance to research. Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] This substance has attracted much attention in the way of research and development.
Study its properties, deconstruct it, and clarify its state in various reactions. After years of study, we gradually know where its characteristics can be used. In the field of industry, it can be used as a catalytic agent to promote rapid reaction; in the field of medicine, it can be used as a preparation material to help drug efficacy.
However, the road of development is not smooth. The preparation method still needs to be refined to increase its yield and reduce its cost. And its impact on the environment also needs to be carefully observed. Only by unremitting exploration and forging ahead can we make achievements in the path of research and development, so that this material can be used by the world and benefit people.
Toxicity Research
In recent years, Yu has dedicated himself to the toxicological research of Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid]. The application of this substance has become more and more widespread, but its toxicity in many fields is unknown, and it needs to be investigated urgently.
Yu Guang searched ancient books and analyzed data in detail. In his laboratory, he strictly operated to observe its effects on organisms. Or cast cells to observe their morphological changes and metabolic differences; or use animals to explore their organ damage and behavioral changes.
After months of research, it has gradually gained something. At low concentrations, it may cause some stress to cells, but it can still recover; at high concentrations, it has significant damage to organs and affects the normal function of the body. Although the research is not complete, it has already revealed its toxicity, which lays a cornerstone for follow-up exploration and application prevention. Hope this research can be used by the industry to make this substance safe and efficient.
Future Prospects
Today there is a thing named Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid]. Looking at its properties, it has extraordinary quality and can be used for all kinds of wonders to benefit the world.
My generation looks to the future, and the development of this thing is limitless. In the field of medicine, it may be able to assist in the research of new drugs and solve the suffering of many diseases; in the field of chemical industry, it may be able to optimize the process and promote the prosperity of the industry. Its potential is like a abyss, and it needs to be dug deep.
With time and careful study, it will be able to expand its use and widely benefit. Make this wonder, glittering light, shine in the future, seek endless benefits for the people of the world, and become an unparalleled career.
Frequently Asked Questions
What is the chemical structure of Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid]?
Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid] has a unique chemical structure. The piperazine ring is a six-membered heterocyclic ring composed of two nitrogen atoms and four carbon atoms alternately connected. At positions 1 and 4 of the piperazine ring, a 2-hydroxypropanesulfonic acid group is connected.
2-hydroxypropanesulfonic acid group, one end of the propyl group is connected to the nitrogen atom of the piperazine ring, while the other position of the propyl group is connected to the hydroxyl group and the sulfonic acid group. Sulfonic acid-SOH gives the substance good water solubility and ionic properties, and plays a key role in many chemical reactions and application scenarios. It can participate in the ion exchange process as an ion exchange check point. The existence of hydroxy-OH increases the hydrophilicity of the molecule on the one hand, and on the other hand enables it to participate in various organic reactions, such as esterification reactions, which expands the chemical activity and application scope of the substance. Overall, the chemical structure of Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid] combines the stability of piperazine ring, the reactivity of hydroxyl group and the ionic characteristics of sulfonic acid group, which determines its unique application value and chemical reaction performance in many fields, such as biomedicine, chemical catalysis, etc.
What are the common uses of Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid]?
Piperazine-1,4-bis [2-hydroxypropanesulfonic acid], often used as a biological buffer, has a wide range of uses in biochemical experiments.
It is indispensable in the study of biological macromolecules such as proteins and enzymes. When isolating and purifying proteins, maintain a stable pH environment to ensure that the structure and activity of proteins are not damaged. Such as chromatographic separation of proteins, at a specific pH value, proteins are separated according to their charge characteristics. This substance is used to precisely regulate pH to obtain high-purity proteins.
Enzyme activity research is also crucial. Enzymes are extremely sensitive to the pH of the reaction environment, and different enzymes have the best pH value. Like the determination of amylase activity, this buffer is used to create a suitable pH, so that the enzyme exhibits the best activity, and accurately explores the catalytic characteristics and kinetic parameters of the enzyme.
In the field of cell culture, it also plays a key role. Cell growth requires strict environmental pH, and small changes may cause abnormal cell metabolism, growth inhibition or even death. Adding this substance can stabilize the pH of the culture medium, create a stable living environment for cells, and ensure normal cell growth and proliferation. It is often used in animal cells, plant cells and microbial cell cultures.
In addition, in electrophoresis experiments, the buffer system needs to stabilize the pH to facilitate the separation of biological macromolecules according to differences in charge and molecular weight. This substance can establish a stable buffer environment, ensuring reliable and reproducible electrophoresis results, and assisting researchers in accurately analyzing the characteristics of biological macromolecules.
What are the precautions for Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid] during storage and transportation?
For piperazine-1,4-bis [2-hydroxypropanesulfonic acid], all matters need to be cautious during storage and transportation.
Although this compound is relatively stable, it still needs to be protected from heat and moisture. It should be placed in a cool, dry and well-ventilated place. If exposed to high temperature, or its properties may vary, it will affect the quality. High humidity environment may also cause deliquescence and other conditions, which will damage its purity.
When transporting, the packaging must be tight to prevent leakage. The packaging material used should be corrosion-resistant to avoid reacting with the compound. And during handling, it should be handled with care to avoid damage to the packaging.
Furthermore, the place of storage and transportation should be kept away from fire sources, oxidants and other substances. Due to its flammability, it may also react violently when exposed to oxidants, endangering safety.
In addition, the storage place should be clearly marked, indicating the name, characteristics and precautions of the compound. Management personnel should also be familiar with the properties of this substance in order to deal with emergencies. When transporting, relevant personnel also need to know the emergency response methods to ensure the safety of transportation. In this way, the quality and safety of Fangpopiperazine-1,4-bis [2-hydroxypropanesulfonic acid] during storage and transportation are comprehensive.
What are the physicochemical properties of Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid]?
Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid], the Chinese name is often piperazine - 1,4 - (2 - propanesulfonic acid), its physicochemical properties are as follows:
This substance is a multi-white crystalline powder under normal conditions. It is stable in nature and has good water solubility. It can be miscible in water in any ratio to form a uniform transparent solution. Its dissolution process is rapid, and it is weakly acidic in the water. The pH value varies according to the degree. Usually, the pH value of the dilute liquid is around 4.0-6.0.
As far as the melting boiling temperature is concerned, the melting phase is high, and it begins to melt and decompose gradually when it is added to < 300 ° C. This high melting property makes it possible to maintain a solid state in normal conditions. Its decomposition degree also shows that the biochemical properties can be changed under a certain degree of high temperature, and the quality is good.
In addition, it has a certain ability. In some chemical or biological systems, it can maintain the pH value of the phase, and resist the large pH wave caused by the addition of a small amount of acid. This property makes it important in biological chemical analysis, chemical analysis, and other fields. The isofunctional properties of the sulfonic acid group in the synthesis show that it can not only provide some nuclear substitutions, but also show certain acidic phase inverse properties, which can be used as an important component in the synthesis of polymers.
What are the synthesis methods of Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid]?
To prepare Piperazine - 1,4 - Bi [2 - Hydroxypropanesulfonic Acid], the following method is often followed.
First take an appropriate amount of piperazine and place it in a clean reaction vessel. Use an alcohol solvent such as ethanol to fully dissolve it to create a homogeneous reaction environment. In addition, take a specific reagent containing hydroxyl groups and sulfonic acid groups, such as 2-hydroxy-1-propanesulfonic acid derivatives, and slowly add it to the above piperazine solution according to the appropriate amount ratio of substances. Here, it is necessary to precisely control the ratio of the two, which is one of the keys to this product.
In the reaction system, add an appropriate amount of catalyst, such as some organic acids or organic bases, to promote the efficient progress of the reaction. Control the reaction temperature, generally maintained in a moderate range, about 50-80 degrees Celsius, not too high to cause side reactions, nor too low to slow down the reaction. During the reaction, continue to stir to make full contact with the reactants.
After several reactions, when the system is stabilized, use thin-layer chromatography or other suitable analytical means to monitor the reaction process until piperazine and 2-hydroxy-1-propanesulfonic acid derivatives are exhausted, the product is obtained.
After the crude product is separated and purified, column chromatography is preferred, and appropriate stationary and mobile phases are selected to effectively separate the product from impurities. After recrystallization, the product was further purified with a suitable solvent, such as ethanol-water mixed solvent, to obtain high-purity Piperazine-1,4-Bi [2-Hydroxypropanesulfonic Acid], and its structure and purity were confirmed by testing methods.