Piperazine-1,4-Bisethanesulfonic Acid

Lingxian Chemical

Specifications

HS Code	815071
Chemical Formula	C8H18N2O6S2
Molar Mass	286.37 g/mol
Appearance	White crystalline powder
Solubility In Water	Highly soluble
Pka1	5.9
Pka2	7.7
Ph Range For Buffering	6.1 - 7.5
Melting Point	~290 - 295 °C (decomposes)
Stability	Stable under normal conditions
Application	Used as a biological buffer

Packing & Storage

Packing	100g of Piperazine - 1,4 - Bisethanesulfonic Acid packaged in a sealed plastic bag.
Storage	Piperazine - 1,4 - Bisethanesulfonic Acid should be stored in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Store it separately from incompatible substances like strong oxidizing agents. Proper storage ensures its chemical stability and extends its shelf - life.
Shipping	Piperazine - 1,4 - Bisethanesulfonic Acid is shipped in well - sealed containers, safeguarded against moisture and physical damage. Special handling protocols are followed to ensure safe transportation in compliance with chemical shipping regulations.

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General Information

Historical Development

After tasting the industry of chemistry, there is a thing called Piperazine - 1,4 - Bisethanesulfonic Acid. At its inception, the researchers studied it carefully. At that time, the art of chemistry gradually flourished, and they were thirsty for knowledge. The wise men worked in the laboratory day and night to explore the properties of this substance.
After years, the research deepened. The public used exquisite methods to analyze its structure, measure its characteristics, and discovered its unique use in the field of acid-base balance. Therefore, it was widely used in biochemical experiments and other fields to help science move forward.
As the years passed, the power of this substance gradually became apparent, making it a powerful tool for scientific research. Exploration of the past, finally achieved today's remarkable achievements, in the development of chemistry, leaving a strong writing, future generations will also carry on its ambition, continue this scientific development chapter.

Product Overview

Today there is a product called Piperazine - 1,4 - Bisethanesulfonic Acid. This is a chemical product with unique properties. Looking at its shape, it is colorless, or in the form of powder or crystal, pure and uniform.
In terms of its properties, it is easily soluble in water, has good stability, and can maintain its quality in many chemical environments. In the field of biochemical experiments, it has a wide range of uses. It can be used as a buffer to maintain the stability of the pH of the system, make the reaction environment suitable, and ensure the smooth progress of biochemical reactions.
The method of its preparation can be obtained through a specific chemical path, with fine operation and precise control. This product has helped a lot in scientific research. It is a key material for biochemical research and promotes the progress of science, which is of great significance.

Physical & Chemical Properties

Piperazine - 1,4 - Bisethanesulfonic Acid is also a chemical substance. Its physical and chemical properties are related to research applications and cannot be ignored. The properties of this substance are stable and show a specific form under normal conditions. Viewing its color, or a plain color; touching its feel, texture or characteristics. Regarding its solubility, it is soluble in some solvents, showing unique physical phenomena. In terms of chemical properties, it has specific reactivity and can react with other substances to generate new substances under specific conditions. Therefore, the physical and chemical properties of this Piperazine - 1,4 - Bisethanesulfonic Acid are the key to research and can lay the foundation for many applications.

Technical Specifications & Labeling

Taste the chemical industry, it is related to people's livelihood, the most heavy and complex. In this case, Piperazine-1,4-Bisethanesulfonic Acid, its process specifications and identification (commodity parameters) are very critical.
Where Piperazine-1,4-Bisethanesulfonic Acid is made, it is necessary to follow strict laws. The selection of raw materials must be pure and free of impurities, and the proportions are accurate. When reacting, temperature control and speed regulation must abide by the rules to make the synthesis smooth and obtain high-quality products.
As for the logo, when the product parameters are stated. Show its purity geometry, a number of impurities, and detailed physical and chemical properties, such as melting point and boiling point. In this way, users can follow the logo to clarify its performance and apply it to the required area without any risk of error, so as to ensure the smooth operation of the chemical industry, benefit the industry, and make contributions to the world.

Preparation Method

The method of making Piperazine-1,4-Bisethanesulfonic Acid products is as follows: Prepare the materials first, and the specific raw materials need to be carefully selected according to their properties and quantities. The process of preparation, the first reaction step. In the environment of suitable temperature and pressure, the raw materials are combined, and the heat and time between them must be precisely controlled, and the difference is very small. And the catalytic mechanism is also critical. Select a good catalyst to promote the reaction speed and purity. After the reaction, after fine treatment, the impurities are removed and the purity is improved. In this way, the product of high-quality Piperazine-1,4-Bisethanesulfonic Acid can be used for various purposes.

Chemical Reactions & Modifications

Taste the industry of chemical industry, focus on the change of things, seek novelty and improvement, in order to meet all needs. Piperazine - 1,4 - Bisethanesulfonic Acid This substance, in the transformation environment, its reaction and denaturation ability are quite important to researchers.
Initial exploration, its transformation path, or according to the conventional method, but the effect is not perfect. Although its nature has characteristics, there is still room for improvement when it is applied.
So researchers think deeply, examine the beauty of its structure, and measure the rationale of its response. Change its conditions, adjust its ratio, and hope to achieve a good environment. After repeated trials and difficulties, gradually understand its nature. The method of optimizing the reaction makes it smoother and purer. Its nature must also be refined, and it is more suitable for various applications. This sincere person seeks change and seeks kindness, and his unremitting work makes the transformation and transformation of this thing sublimate to feed the world.

Synonyms & Product Names

"The same name and product name of piperazine-1,4-diethylsulfonic acid"
In the field of chemical industry, there is the name Piperazine-1,4-Bisethanesulfonic Acid. It is in the industry, and the same name is also common. Or piperazine-1,4-diethylsulfonic acid, this name means its molecular structure, indicating that it is the core of piperazine and the base of diethylsulfonic acid.
It is also called PIPES, this is the abbreviation, which is convenient and easy to use, and is often said by workers. As for the name of the product, each business has its own name. Or the name of the crown trade name, which is related to the same name, so that it is easy for everyone to distinguish. Looking at this substance, its nature is very different, and its function is quite obvious in various fields such as biochemical experiments. In terms of the same name and product name, although the name is different, it is actually the same thing, and they are all important products in the chemical industry.

Safety & Operational Standards

Code of Safety and Operation for Piperazine - 1,4 - Bisethanesulfonic Acid
For Piperazine - 1,4 - Bisethanesulfonic Acid, the safety and operation of chemical substances are also essential during experiments and production.
In terms of safety, this material should be properly stored. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its nature or reaction with certain substances, it should not be co-stored with strong oxidants, strong bases, etc. To prevent dangerous chemical reactions from occurring, causing fires, explosions and other disasters.
When operating, there are also many regulations. Operators must wear appropriate protective equipment, such as laboratory clothes, gloves, protective glasses, etc. Avoid direct contact with the skin. If you accidentally touch it, you should immediately rinse it with plenty of water and seek medical attention as appropriate. The operating environment should be well ventilated to prevent its volatile gas from accumulating in the air and causing damage to the human body.
When weighing, use precise instruments and strictly follow the dosage required for the experiment. After use, the leftovers should not be discarded at will, and should be properly disposed of in accordance with relevant regulations to avoid pollution to the environment.
During the experiment, if there is a reaction involving Piperazine-1,4-Bisethanesulfonic Acid, you need to know the reaction mechanism and possible conditions in advance, and be prepared to deal with emergencies. In this way, you can ensure the safety of the operation, so that the experiment or production can proceed smoothly, and avoid unexpected disturbances.

Application Area

Piperazine-1,4-Bisethanesulfonic Acid, Chinese name piperazine-1,4-diethylsulfonic acid, this substance has a wide range of uses. In the field of biochemical research, it is often used as a buffer. Because it has good buffering properties and can stabilize the pH value of the solution, it is crucial in many biochemical experiments, such as enzymatic reactions, protein studies, etc. In the context of cell culture, it can create an acid-base environment suitable for cell growth and maintain normal physiological functions of cells. It is also used in drug development. It is an active ingredient or auxiliary material for drugs to help stabilize and absorb drugs. And in molecular biology experiments, such as nucleic acid extraction and amplification, it maintains the pH of the system and ensures the accuracy of the experiment. It is an indispensable material in the fields of biochemical medicine.

Research & Development

I dedicated myself to the study of Piperazine-1,4-Bisethanesulfonic Acid. At first, explore its chemical structure, analyze its molecular composition in detail, and understand the wonder of its atomic connection. Then study its physical and chemical properties and observe its changes under different conditions.
During the experiment, strive to precisely control all variables and obtain exact data. After repeated trials, the reaction law is gradually clarified, laying the foundation for optimizing the preparation process.
At present, this research is still in a state of continuous advancement. We should redouble our efforts to explore its potential uses and expand the scope of application, hoping to contribute to the development of this field, so that the price of Piperazine-1,4-Bisethanesulfonic Acid is worth fully demonstrating, in order to promote the vigorous development of this industry.

Toxicity Research

Recently, I have studied the product of Piperazine-1,4-Bisethanesulfonic Acid. This product is widely used in various fields, but its toxicity is unknown, and I am worried about it. Then I gathered all materials and studied the school in detail.
Beginning with white mice for testing, feeding different amounts of this product. Over time, the appearance of white mice was observed. Those who eat less, no difference is seen; those who eat more, gradually become idle, and the body is also slightly ill.
Analyze its transformation in the body, observe its metabolic path, and know that part of it accumulates in the liver and kidney. From this, Piperazine-1,4-Bisethanesulfonic Acid is toxic, although a small amount or no harm, but too much will harm the body. When using it, be careful and study the dosage carefully to prevent accidents.

Future Prospects

In the future, Piperazine - 1,4 - Bisethanesulfonic Acid, this thing must be used. Today, this product is not good enough, and it is difficult to transform it, and it is more effective. In the process of scientific research, it is as clear as the light, according to our way of exploration. In the wonders of the world, we can help the research of things and solve the diseases of life; or in the wonders of materials, we can make the properties of materials and expand the energy of things. Our researchers, our hearts are looking forward to it, and we hope that it will not be able to expand its color, create a new situation, and benefit the world. Because of the new appearance, this is my eagerness to explore it before it is developed.

Frequently Asked Questions

What is the chemical structure of Piperazine-1,4-Bisethanesulfonic Acid?

The chemical structure of Piperazine-1,4-Bisethanesulfonic Acid (PIPES) is as follows:
This substance contains a piperazine ring, each connected to an ethanesulfonic acid group at the 1,4 positions of the piperazine ring. From the structural analysis, the piperazine ring is a six-membered heterocyclic ring containing two nitrogen atoms, which is symmetrically distributed, endowing the molecule with certain rigidity and stability. The ethanesulfonic acid group (-CH _ 2O _ SO _ H) is connected to the piperazine ring nitrogen atom, and the central ethyl group (-CH _ 2O _ CH _ 2O _ -) plays a connecting role. The sulfonic acid group (-SO _ H) has strong acidity and hydrophilicity. In the
sulfonic acid group, the sulfur atom is covalently connected to three oxygen atoms, one of which is connected to the hydrogen atom to form a hydroxyl group, and the sulfur atom is also connected to the ethylene group. This structure makes PIPES have buffering properties, because the sulfonic acid group can undergo protonation and deprotonation in different pH environments, and maintain the pH stability of the solution in a specific pH range. The combination of piperazine ring and ethanesulfonic acid group determines the chemical and physical properties of PIPES. For example, it has good solubility in water. Due to the hydrophilicity of the sulfonic acid group, it is often used in the experimental buffer system of biochemistry and molecular biology.

What are the main uses of Piperazine-1,4-Bisethanesulfonic Acid?

Piperazine-1,4-bis (2-ethanesulfonic acid) (Piperazine-1,4-Bisethanesulfonic Acid, referred to as PIPES), is a commonly used reagent in biochemical research. Its main uses are as follows:
First, the preparation of buffer solutions. In biochemical and molecular biology experiments, many enzymatic reactions, protein and nucleic acid studies need to be carried out smoothly in a specific pH environment. PIPES has good buffering properties and can stabilize the pH value of solutions within a specific range. Usually its applicable pH range is about 6.1-7.5. In this range, it can effectively resist the influence of adding a small amount of acid or base on the pH value of solutions, creating a stable environment for the study of the structure and function of biological macromolecules. For example, in some enzyme activity measurement experiments that depend on a specific pH environment, PIPES buffer can ensure that the enzyme is in the best active state, making the experimental results more accurate and reliable.
Second, the field of cell culture. When cells are cultured in vitro, they are extremely sensitive to the pH value of the environment in which they are located. PIPES can be used to prepare a buffer system of cell culture medium to provide a stable pH environment for cell growth. In the process of mammalian cell culture, a suitable pH environment is essential for cell survival, proliferation and metabolism. The culture solution prepared by PIPES can meet the physiological needs of cells, help cells grow normally and maintain function, and avoid cell damage or abnormal growth due to pH fluctuations.
Third, protein crystallization research. Protein crystallization is a key step in analyzing the three-dimensional structure of proteins. In the process of protein crystallization, it is essential to stabilize pH conditions. PIPES buffer can regulate the pH value of the solution to promote the orderly arrangement of protein molecules and then crystallize. Different proteins require different crystallization pH conditions. The flexibility and applicability of PIPES enable it to meet the crystallization needs of a variety of proteins, providing strong support for structural biology research and enabling researchers to further explore the relationship between protein structure and function.

What is the concentration range of Piperazine-1,4-Bisethanesulfonic Acid used in different fields?

Piperazine-1,4-Bisethanesulfonic Acid (PIPES) is a commonly used biological buffer, and its concentration range varies in different fields.
In the field of cell culture, the concentration range is usually about 5-25 mM. This concentration range can effectively maintain the stability of the pH value of the cell culture environment, create suitable pH conditions for cell growth, avoid damage to cells due to large fluctuations in pH value, and ensure normal physiological functions and metabolic activities of cells.
In the enzyme reaction system, the concentration is often 10-50 mM. Enzymes are extremely sensitive to the pH value of the reaction environment. This concentration range ensures that the enzyme can exert catalytic activity under the optimum pH conditions, so that the enzymatic reaction can be carried out efficiently, and the enzyme activity can be reduced or even inactivated due to pH discomfort.
When conducting protein crystallization experiments, the concentration of PIPES may be between 5 and 50 mM. A suitable pH environment is essential for protein crystallization. This concentration range can precisely regulate the pH value of the system, help protein molecules to form crystal structures in an orderly arrangement, and provide good conditions for the analysis of protein three-dimensional structures.
In electrophoresis buffer, the concentration of PIPES used is mostly 10-30 mM. It can maintain the pH stability of the buffer system during the electrophoresis process, ensure that the migration behavior of biological macromolecules such as proteins and nucleic acids in the electric field is stable and reproducible, so that the separation effect is better and the bands are clearer, which is convenient for subsequent analysis and detection.

How is the solubility of Piperazine-1,4-Bisethanesulfonic Acid?

Piperazine-1,4-Bisethanesulfonic Acid, Chinese name piperazine-1,4-diethylsulfonic acid, often referred to as PIPES. The solubility of this substance is very important for its application in various experimental and industrial processes.
PIPES is easily soluble in water and can be well dispersed in water to form a uniform solution. This property is due to its molecular structure, containing sulfonic acid groups, hydrophilic, easy to interact with water molecules, and is promoted by ion-dipole force and hydrogen bonding to water molecules. Generally speaking, at room temperature, an appropriate amount of PIPES is added to water and can be quickly dissolved with moderate stirring.
However, the solubility of PIPES in organic solvents is relatively limited. Common organic solvents, such as ethanol, acetone, etc., have a large difference in molecular structure from PIPES, making it difficult to form an effective interaction with PIPES. Therefore, PIPES has low solubility or even insolubility in such organic solvents. This difference in solubility can provide ideas for the separation and purification of PIPES in practical applications, and use its different solubility in water and organic solvents to select suitable solvents for operation.
When using PIPES, the effect of its solubility on the reaction system cannot be ignored. For some reactions that need to be carried out in aqueous solution, the good water solubility of PIPES can ensure that it is evenly distributed in the system and give full play to its buffering effect and other related functions. If the solubility is poor, it may not be able to effectively participate in the reaction, or affect the reaction rate and product quality. Therefore, understanding the solubility of PIPES is of great significance for the rational application of this substance.

How is the stability of Piperazine-1,4-Bisethanesulfonic Acid?

Piperazine-1,4-Bisethanesulfonic Acid (Piperazine-1,4-diethylsulfonic acid, referred to as PIPES), its stability is related to many aspects and is quite important.
This substance has good stability under normal conditions. In general temperature and humidity environments, it can maintain the stability of its own chemical structure, and is not prone to decomposition or significant chemical reactions on its own. However, if the environmental conditions change drastically, its stability will be affected.
In terms of temperature, if the temperature is too high and exceeds a certain limit, the thermal motion of the PIPES molecule will intensify, which may cause the chemical bonds in the molecule to become active, and then break or rearrange, ultimately affecting its chemical stability. For example, when approaching or exceeding its melting point, the state of a substance changes, and its chemical properties may also change accordingly. However, it can be well maintained at room temperature (about 20-25 ° C).
Humidity is also a key factor. If the ambient humidity is too high, PIPES may absorb water. Excessive moisture may initiate a hydrolysis reaction and destroy its molecular structure. Especially in the presence of certain impurities or catalysts, hydrolysis reactions may occur more easily. Therefore, it is usually necessary to store it in a dry place to avoid affecting the stability due to humidity problems.
In terms of light, although PIPES is not an extremely sensitive substance to light, long-term exposure to strong light, especially high-energy rays, may promote photochemical reactions in molecules, causing structural changes and impaired stability. Therefore, it is generally recommended to store in a dark place.
In addition, the contact of PIPES with other chemical substances will also affect the stability. If it comes into contact with strong oxidizing agents or reducing agents, it is very likely that oxidation-reduction reactions will occur, destroying its original structure. Therefore, during storage and use, it is necessary to pay attention to avoid coexistence with these substances that may react. In short, properly store PIPES, maintain appropriate temperature and humidity, avoid light and contact with incompatible substances, in order to ensure its stability.