Products

Piperazine-N,N'-Bis(2-Hydroxypropanesulfonic Acid) Dihydrate

Lingxian Chemical

Specifications

HS Code

629726

Chemical Formula C10H22N2O10S2·2H2O
Molar Mass 432.47 g/mol
Appearance White crystalline powder
Ph Range For Buffer 6.1 - 7.5
Solubility In Water Highly soluble
Pka1 6.8
Pka2 8.2
Melting Point ~125 - 127 °C
Density ~1.49 g/cm³
Buffer Capacity Effective in its pH range
Stability Stable under normal conditions
Packing & Storage
Packing "1 kg bag packaging for Piperazine - N,N'-Bis(2 - Hydroxypropanesulfonic Acid) Dihydrate."
Storage Piperazine - N,N'-Bis(2 - Hydroxypropanesulfonic Acid) Dihydrate should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption, which could affect its chemical properties. Store it separate from incompatible substances, such as strong oxidizing agents, to avoid potential reactions and ensure its stability over time.
Shipping Piperazine -N,N'-Bis(2 - Hydroxypropanesulfonic Acid) Dihydrate is shipped with strict safety measures. Packed securely in suitable containers, they are transported following hazardous chemical regulations to ensure safe arrival.
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Piperazine-N,N'-Bis(2-Hydroxypropanesulfonic Acid) Dihydrate
General Information
Historical Development
Piperazine - N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, the development of this substance has gone through years of changes. At the beginning, chemical research was not mature, and the understanding of this substance was still shallow. However, the road of scientific research is not limited. In the past, scholars worked tirelessly under simple experimental conditions. With the passage of time, technology has gradually emerged, and analytical methods have become more accurate. The investigation of its structure and properties has become more and more in-depth. From the initial exploration of ignorance to the clarification of its characteristics, everyone has paid a lot of effort. This substance has gradually developed its use in chemical, pharmaceutical and other fields. Its development process is like a boat on a long river. Although there are twists and turns, it will eventually welcome the light, lay the foundation for future scientific research, and will continue to affect the process of related fields.
Product Overview
There is a substance called Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate. This substance has unique properties and is a dihydrate. In its structure, the two ends of the piperazine ring are connected with propyl groups containing hydroxyl groups and sulfonic acid groups.
In the experimental environment, it is often used as a buffer. Because it can stabilize the pH of the solution in a specific pH range and ensure the stability of the reaction environment. It can be used in many fields of biochemical research, such as the study of biological macromolecules such as proteins and enzymes, to provide suitable conditions for the smooth progress of the reaction. The characteristics and functions of this substance are quite valuable in the process of chemical research and are a powerful tool for researchers.
Physical & Chemical Properties
To taste a chemical thing, Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, its properties are also related to physical and chemical characteristics, and it is very important. The shape of this thing, or a certain shape, and the color also has its own characteristics. In terms of physical properties, its melting point and boiling point have fixed numbers, which are related to the temporal state of application.
In terms of its chemical properties, it has a certain reactivity. In case of acid and alkali, or change, the stability of its molecular structure also affects many things. It can participate in specific chemical reactions and generate new substances, which is its chemical charm.
The beauty of chemistry lies in exploring the physical and chemical characteristics of things. Although Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate is small, its physical and chemical properties are of deep significance in scientific research and application. Our generation of chemical researchers should explore it in detail to clarify its rationality and make good use of its properties.
Technical Specifications & Labeling
Today there is a product called Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate. Its technical regulations and identification (product parameters) are the key. The technical regulations of this product need to clarify its composition ratio, physical and chemical properties, such as color and taste, degree of melting and boiling, solubility, etc., and must be accurate. In the identification, the product parameters should be listed in detail. Number, specifications, applicable fields, storage methods, etc. In this way, people can use this product to know its properties and laws, so that there is no mistake. Strict compliance with technical regulations and labels is essential to ensure the quality and use of this product.
Preparation Method
To prepare Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, its raw materials and production process are very critical. The raw materials need to be selected from high-quality piperazine to ensure high quality. In the production process, the reaction step is to mix piperazine with a specific sulfonic acid reagent in a certain proportion, and slowly stir the reaction at a suitable temperature and pressure to make the two fully contact and combine. When the reaction is initially completed, it needs to be purified by a mechanism, recrystallization, chromatography, etc. to remove impurities and improve the purity of the product. In this way, high-quality Piperazine - N, N' - Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate can be prepared to meet the needs of experiment and production.
Chemical Reactions & Modifications
The industry of chemical industry is related to the change of all things. Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, in the field of chemistry, its reaction and modification are worth studying.
Looking at the reaction, and the combination of various reagents, often produce wonderful changes. Or from the reaction of combination, the molecules blend, the structure is reformed, and then a new substance is formed. The mechanism, such as the combination of yin and yang, is subtle and difficult to measure.
Discuss modification, or adjust its pH, or change its temperature and humidity, in order to optimize performance. Make it in different situations, can develop its strengths. After modification, the stability is increased, the activity is also suitable, and it is more convenient for industrial and scientific research purposes.
Chemical matters, such as exploring the secrets, the research on the reaction and modification of Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, will never end, and more new gains will be expected to benefit the world.
Synonyms & Product Names
Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate is an important substance in chemical research. Its common names are also diverse. In the industry, there may be aliases, although this alias is different from the official name, it all refers to the same thing. This product is unique in nature and is involved in experimental and industrial applications. Its chemical structure is exquisite and its role is significant. It can often play a key role in reactions and is indispensable for many research and production processes. Although the names are different, they all refer to this Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate. Chemists need to clarify its different names when studying, so that they can be used accurately to promote the progress of scientific research and make it play a greater role in the field of chemistry.
Safety & Operational Standards
Safety and Operation Specifications of Piperazine - N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate
Piperazine - N, N' -Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate is a commonly used substance in chemical research. Its safety and operation specifications cannot be ignored.
On the safe side, if this substance accidentally touches the skin, rinse it with plenty of water as soon as possible, and observe whether the skin is uncomfortable. If there is any abnormality, seek medical treatment. If it enters the eye, do not rub it, rinse it with flowing water or normal saline immediately, and seek medical attention in time. As for inhaling the dust of this substance, you should leave the site as soon as possible and go to a place where the air is fresh. If you feel that you are not breathing well, you must seek medical attention.
In terms of operating specifications, the experimental site should be well ventilated to disperse harmful gases that may be generated. The operator must wear suitable protective clothing, such as laboratory clothes, gloves, etc., and goggles are also indispensable to prevent the substance from splashing out and hurting the eyes. When using this substance, you should handle it with care. Take tools and methods according to the exact amount, and do not let it spill. After use, store it properly in a cool, dry and ventilated place, away from fire and heat sources. When discarded, it should also comply with relevant environmental regulations and should not be discarded at will to avoid polluting the environment.
In this way, when using Piperazine - N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, strict safety and operating standards are adhered to to to ensure the smooth operation of the experiment, and the safety of personnel and the environment.
Application Area
Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate is widely used in the field of biochemistry. In the research and development of pharmaceutical preparations, because of its good buffering properties, it can stabilize the pH value of the liquid, ensure the activity and stability of the drug ingredients, and make the drug play the best effect. In biological experiments, it is also often used as a buffer to maintain the stability of the pH of the experimental system, ensure that the structure and function of biological macromolecules are not disturbed by pH changes, and lay the foundation for accurate experimental results. In addition, in some chemical production processes, with its unique chemical properties, it can optimize reaction conditions, improve product quality and output efficiency. It is an indispensable important chemical in many fields and has broad application prospects.
Research & Development
I have been studying the chemical product Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate for a long time. This material quality is special and can be used in various fields. At first, explore its properties, destruct its structure, and know its effect in the reaction. Then study its preparation method, find its purity, and increase its yield. During the process, we encountered various problems, such as impurities that were difficult to remove, and the yield did not meet expectations. However, we have been unremitting. After repeated tests, we have adjusted the conditions and changed the process. Progress has been made, and the purity of the product has gradually increased, and the yield has also improved. In the future, if we want to expand its application, we will widely promote it in the fields of medicine, chemical industry, etc., hoping that it can add new color to the industry, promote the development of the industry, and make unremitting efforts to make the results of our research more widely used.
Toxicity Research
I have heard that all things contain properties, and the study of poisons is related to the health of people's livelihood, which cannot be ignored. Today there is Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, and the study of its toxicity is particularly important. We use scientific methods to observe its properties in detail. Or observe its impact on living things, or explore its changes in the environment. Observe the path of its entry into the body, and observe the signs of its onset. After repeated experiments, record its feelings in detail, hoping to understand the toxicity of this substance. When it is used for the world, it avoids harm and seeks profit, protects everyone's well-being, and makes the best use of it without causing disaster. The study of such toxicity is the heavy responsibility of our scientific research, and we will live up to our mission if we keep doing it.
Future Prospects
Piperazine - N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate has gradually become more and more important in today's academic circles. Although it is not widely used at present, its future development can be looked forward to.
Looking at its properties, it has a specific quality. In the field of biochemistry, it can be used as a buffer agent to stabilize the environment of acid and alkali, and to ensure the stability of the reaction. In the path of medical research, it may also have its own uses, the system of pharmaceutical aids, and the safety of cells.
Although the technology is not perfect today, the application is still being explored, but with time, it will be able to shine in many places. At that time, it may become a treasure in the biochemical world, making outstanding contributions to the advancement of scientific research and the benefit of people's livelihood.
Frequently Asked Questions
What are the chemical properties of Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate?
Piperazine -\ (N\),\ (N '\) -bis (2-hydroxypropanesulfonic acid) dihydrate, which is a commonly used chemical reagent in the field of fine chemicals. It has unique chemical properties and is widely used in many fields.
Looking at its physical properties, it is a white crystalline powder under normal conditions, with stable properties, can maintain its own shape in air, and is not easy to volatilize. This substance is highly soluble in water, forming a uniform and transparent solution. This solubility makes it convenient to operate in solution system experiments and production.
In terms of chemical properties, it is weakly acidic, and can release protons under appropriate conditions due to the sulfonic acid group in its molecular structure. In chemical reactions, it can be used as a buffer, because it can interact with acids and bases, effectively maintaining the stability of the reaction system\ (pH\) value. In biochemical experiments, many enzymatic reactions are extremely sensitive to\ (pH\), which can ensure that the enzyme is active in a suitable\ (pH\) environment and avoid enzyme inactivation due to large fluctuations in\ (pH\), which affects the experimental results.
Furthermore, because of its hydroxyl group, it can participate in a variety of organic synthesis reactions, such as esterification with carboxyl-containing compounds, providing rich possibilities for the field of organic synthesis, which can be used to prepare compounds with specific structures and functions.
Piperazin-\ (N\),\ (N '\) -bis (2-hydroxypropanesulfonic acid) dihydrate plays a key role in biochemistry, medicine, organic synthesis and other fields due to its stable physical properties and unique chemical activity, and has become an indispensable substance in many scientific research and production processes.
Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate is commonly used in which experiments
Piperazine-N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, Chinese name piperazine-N, N' -bis (2-hydroxypropanesulfonic acid) dihydrate, often abbreviated as POPSO-2H 2O O, which is a commonly used zwitterion buffer in biochemical research. Due to its unique chemical properties, it has important applications in many experimental scenarios.
In protein research experiments, POPSO-2H 2O O is often used to maintain a stable pH environment. Proteins are extremely sensitive to the pH value of their environment, and slight deviations may cause damage to their structure and function. POPSO-2H2O can stabilize the pH value of the solution within a specific range, creating a suitable living environment for proteins, and enabling researchers to better explore the properties, structures and functions of proteins. For example, in protein crystallization experiments, precise pH regulation is the key to obtaining high-quality protein crystals, and POPSO-2H2O plays an indispensable role in this process.
Enzyme research experiments also frequently use POPSO-2H2O. Enzymes are used as biocatalysts, and their activity is significantly affected by pH. Different enzymes have the best activity under specific pH conditions. POPSO-2H2O can build a suitable pH environment according to the characteristics of the studied enzyme to ensure the efficient activity of the enzyme, so as to facilitate in-depth study of the catalytic mechanism and kinetic parameters of the enzyme.
In cell culture experiments, POPSO-2H2O O is also crucial. Cell growth requires a stable pH environment. POPSO-2H2O can effectively buffer the acidic or alkaline substances produced by cell metabolism, maintain the pH stability of cell culture medium, and provide a strong guarantee for the normal growth and proliferation of cells. In addition, in some nucleic acid-related experiments, such as nucleic acid extraction, purification, and amplification, the stable pH environment created by POPSO-2H2O helps to maintain the structural integrity of nucleic acids and avoid nucleic acid degradation due to pH fluctuations, thus ensuring the smooth progress of the experiment and the accuracy of the results.
What is the price range of Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate?
Piperazine-N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, Chinese name piperazine-N, N' -bis (2-hydroxypropanesulfonic acid) dihydrate, often referred to as POPSO-2H 2O O, is a commonly used buffer in biochemical research. Its price range varies depending on many factors, making it difficult to determine.
One is related to product purity. The higher the purity, the higher the price. Scientific research-grade high-purity products have very few impurities and can accurately meet the needs of high-end experiments. The preparation process is complicated and the cost is high, so the price is high. If the purity reaches more than 99%, the price per gram may be tens of yuan. The industrial-grade purity is slightly lower, contains some impurities, and is used in industrial production with low requirements. The price is relatively low, per gram or several yuan.
Second, the manufacturers are different. Well-known large factories have mature production processes, strict quality control, stable and reliable product quality, large brand influence, and often higher prices. Small factories are competitive markets, and prices may be favorable, but product quality is uneven.
Third, the purchase volume has a great impact. If the purchase volume is small, if you only buy a few grams, the unit price will be high. If you buy a large amount, the manufacturer may give price concessions due to economies of scale, reduced sales costs, etc. When the quantity is large, the price per gram may be reduced by several yuan.
Fourth, market supply and demand determine the price. In peak demand season, supply is tight and prices rise; in off-season or oversupply, prices have room to fall.
Generally speaking, laboratories purchase scientific research-grade products in small quantities, and the price per gram may be 20-50 yuan; for large industrial purchases, the price per kilogram may be in the thousands of yuan, discounted by several yuan per gram. For specific prices, you need to inquire with suppliers and compare the quotations of different manufacturers, different purity and purchase quantity to obtain a suitable price.
How to store Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate
Piperazine-N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, Chinese name piperazine-N, N' -bis (2-hydroxypropanesulfonic acid) dihydrate, often referred to as POPSO-2H 2O O, is a commonly used amphoteric ion buffer in biochemical research. Its storage method is crucial, related to its quality and utility, as follows:
First, temperature control. This compound should be stored at a low temperature, and the optimal temperature range is 2-8 ° C. Low temperature environment can effectively slow down its chemical change rate, inhibit decomposition and deterioration caused by excessive temperature, and maintain its chemical stability. If placed in a high temperature environment, the thermal movement of molecules intensifies, which may cause chemical bonds to break and structure to change, which in turn affects its buffering properties.
Second, the prevention of humidity. Because of its certain hygroscopicity, it is necessary to ensure that the storage environment is dry. If the humidity is too high, it is easy to absorb moisture in the air, which not only changes its water content and affects its purity, but also may cause deliquescence, causing it to agglomerate and deteriorate. When storing, a well-sealed container should be selected, or a desiccant should be placed at the storage place to reduce the ambient humidity.
Third, it should be stored away from light. Light, especially direct light, may cause photochemical reactions, causing changes in its structure and properties. Therefore, it should be placed in a brown bottle or an opaque container and stored in a dark place to avoid adverse effects of light.
Fourth, isolate the air. Oxygen, carbon dioxide and other components in the air, or react with the compound. Sealed storage can reduce its contact with the air, prevent oxidation, carbonation and other reactions, and ensure the stability of its chemical properties.
When storing Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, be sure to adhere to the principles of low temperature, dryness, protection from light, and sealing, so as to ensure its quality and make it play its due role in biochemical research and other applications.
What are the alternatives to Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Dihydrate?
Piperazine-N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Dihydrate, which is piperazine-N, N' -bis (2-hydroxypropanesulfonic acid) dihydrate, often abbreviated as POPSO-2H2O O, is a biological buffer. Although this specific chemical is not present in the antiquities mentioned in Tiangong Kaiwu, there are many alternative products available today.
First, 2 - (N - morpholino) ethanesulfonic acid (MES), which is similar to POPSO-2H2O O, is a biological buffer. The pKa value of MES is about 6.15, and it can effectively maintain the pH of the solution in the pH range of 5.5-6.7. It is suitable for a variety of biochemical and molecular biology experiments, such as some enzymatic reactions. Its buffering performance can stabilize the reaction environment and ensure the activity and function of the enzyme, just like POPSO-2H2O O maintains a stable pH in a specific biological system, helping the smooth progress of related reactions.
Second, 4-morpholine ethanesulfonic acid (MOES), also a commonly used biological buffer. Its pKa is about 6.5, and the pH buffer range is 6.0-7.2. MOES is chemically stable and can avoid interfering with reactions in biochemical experiments. For example, during protein purification, it can prevent protein denaturation due to pH fluctuations, just like POPSO-2H2O O maintains the stability of the system, so that the protein retains its inherent structure and activity.
Its third, tris (hydroxymethyl) aminomethane (Tris), although the pKa value is about 8.1, the pH range is 7.0-9.0, which is different from POPSO-2H2O O, but it is widely used in the field of biochemistry. Tris can be formulated with a variety of buffers for electrophoresis, immunoblotting and other experiments. In the electrophoresis buffer, Tris can adjust the pH to ensure the stable migration of proteins or nucleic acids in the electric field, and POPSO-2H2O is also responsible for maintaining a stable environment in a specific experimental system, both of which are the keys to ensure the smooth development of the experiment.