What is the chemical structure of Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Sesquisodium Salt
Piperazine -\ (N\),\ (N '\) -bis (2-hydroxypropanesulfonic acid) sesquinone salt, this is a rather complex organic compound. The analysis of its chemical structure needs to be viewed step by step from the components.
First of all, piperazine, which is a six-element nitrogen-containing heterocyclic compound, has two nitrogen atoms, and has a symmetrical structure, resembling a ring-like structure. It is like a delicate circular pavilion. The pillars of the pavilion are nitrogen atoms, and the framework of the ring is composed of carbon atoms and hydrogen atoms.
Look again at\ (N\),\ (N '\) -bis (2-hydroxypropanesulfonic acid), this part is connected to two nitrogen atoms of piperazine. Among them, 2-hydroxypropanesulfonic acid contains hydroxyl groups, propyl groups and sulfonic acid groups. Hydroxyl groups are like smart spirits, giving compounds a certain degree of hydrophilicity; propyl groups are like bridges, connecting different groups; sulfonic acid groups are like strong adsorbents, with strong acidity and hydrophilicity. Two 2-hydroxypropanesulfonic acids are connected to piperazine through nitrogen atoms, like two arms stretched out on both sides of a pavilion, each holding a unique group combination.
Finally, it is the sesquinone salt, which means that there are sodium ions in the compound combined with it, and the ratio of sodium atoms to the overall compound is a specific "half-times" relationship. The existence of sodium ions is like adding a unique decoration to this complex chemical building, changing its physical and chemical properties, such as affecting its solubility and stability.
The chemical structure of this compound is actually the result of the ingenious combination of various groups, and each part works together to endow it with unique chemical properties and application potential.
What are the main uses of Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Sesquisodium Salt
Piperazine - N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Sesquisodium Salt, which is piperazine - N, N' -bis (2-hydroxypropanesulfonic acid) sesquicum salt, is widely used.
In the field of biochemical research, it is often used as a buffer. Because biochemical reactions are extremely sensitive to environmental pH, this substance can maintain the stability of the pH value of the reaction system and ensure the smooth and orderly progress of various biochemical reactions. It is like a solid foundation for biochemical reactions, enabling many enzymatic reactions, protein and nucleic acid research experiments to be carried out smoothly.
In the field of medical testing, it is also indispensable. In the process of medical testing, many testing items require a specific pH environment. This substance can precisely regulate the pH of the reaction solution, ensure the accuracy of the test results, and provide a reliable basis for doctors to diagnose the disease, just like the key guarantee for the accuracy of medical testing.
In the scene of cell culture, this substance also makes outstanding contributions. When cells are cultured in vitro, they have strict environmental requirements. It can adjust the pH of the medium to create a suitable living environment for cells, help cells grow normally, proliferate and metabolize, and create a comfortable home for cells.
In the process of drug development, the role of Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Sesquisodium Salt should not be underestimated. In the process of drug synthesis and preparation, it can be used as a buffer component to ensure drug stability and effectiveness, and at the same time, it can adjust drug pH to enhance drug safety and tolerance, acting as a right-hand assistant for drug development.
Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Sesquisodium Salt What to pay attention to when storing
Piperazine - N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Sesquisodium Salt, that is, piperazine - N, N' -bis (2-hydroxypropanesulfonic acid) sesquisodium salt, should pay attention to the following matters when storing this material.
Bear the brunt, temperature is critical. It should be stored in a cool place, not in a high temperature environment. Due to high temperature, it is very likely that its chemical properties will change, which will affect its quality and efficiency. Generally speaking, it is appropriate to refrigerate in a refrigerated environment of 2-8 ° C, so as to ensure its stability.
Furthermore, humidity should not be underestimated. It should be placed in a dry place, away from a humid place. If the ambient humidity is too high, it is easy to cause it to get damp. Once damp, there may be agglomeration, and in severe cases, it may even cause a chemical reaction, damage its structure, and make it impossible to use normally.
Shading is also a key point. The substance is quite sensitive to light, and light may cause luminescent chemical reactions, causing it to deteriorate. Therefore, it should be stored in an opaque container or stored in a dark place.
In addition, care should be taken to avoid mixing with other chemicals. Due to its special chemical properties, if it comes into contact with certain substances, a chemical reaction may occur. This will not only affect its own quality, but also cause danger.
Be sure to mark it well. Clearly label the name, specifications, storage conditions and valid period. This way, it can be seen at a glance when using it, and it is easy to follow the principle of first-in, first-out to prevent expired use.
When storing Piperazine - N, N '-Bis (2-hydroxypropanesulfonic acid) sesquimetum salt, it must be properly disposed of in terms of temperature, humidity, light, mixing and labeling to ensure that its quality and performance are not compromised.
How safe is Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Sesquisodium Salt?
Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Sesquisodium Salt, that is, piperazine - N, N' - bis (2-hydroxypropanesulfonic acid) sesquicum salt, the safety of this product is related to many aspects.
In terms of its chemical properties, as a sodium salt containing sulfonic acid groups and hydroxyl groups, it is relatively stable under conventional conditions. In general chemical synthesis experiments, if there is no extreme acid-base environment, high temperature hot topic and other special conditions, accidental chemical reactions rarely occur, resulting in harmful by-products.
In the field of biological research, if it is used in cell culture, biological experiments, etc., it has been verified by many experiments that within the appropriate concentration range, it has little interference with cell growth and metabolism. Due to its structural characteristics, it can maintain the acid-base balance of biological systems to a certain extent, and has little impact on the structure and function of biological macromolecules.
In terms of the environment, if this substance is discharged according to the normal route, it can be gradually decomposed into relatively simple and harmless small molecule substances in natural water bodies, soil and other environments by virtue of the degradation of microorganisms. However, if a large amount or disorderly discharge, it may cause short-term acid-base imbalance and other effects on the local ecological environment, but this effect is usually relatively limited, and can be gradually restored through the environment's own buffering and self-purification mechanism.
In terms of human contact, a small amount of contact with skin and mucous membranes generally does not cause strong irritation, allergic reactions. If accidentally inhaled or ingested, it is weakly alkaline and has low toxicity. As long as it is treated in time, such as rinsing with water, inducing vomiting, etc., it usually does not cause serious and lasting harm to the human body.
In summary, Piperazine - N, N '- Bis (2 - Hydroxypropanesulfonic Acid) Sesquisodium Salt is quite safe under normal use and operating conditions, but it still needs to follow the corresponding specifications during use to ensure safety.
Piperazine-N, N '-Bis (2-Hydroxypropanesulfonic Acid) Sesquisodium Salt
Piperazine-N, N '-Bis (2 - Hydroxypropanesulfonic Acid) Sesquisodium Salt, that is, piperazine-N, N' -bis (2-hydroxypropanesulfonic acid) sesquimetum salt, has been prepared by means of chemical synthesis throughout the ages.
One method is based on piperazine, first combining piperazine with an appropriate halogenated hydroxypropanesulfonate. This halogenated hydroxypropanesulfonate needs to be prepared in advance, and can be obtained by reacting hydroxypropane with halogenating agents and sulfonating agents in an appropriate order and under suitable conditions. Then, the nitrogen atom of piperazine reacts with the halogen atom of halogenated hydroxypropanesulfonate through nucleophilic substitution to form piperazine-N, N '-bis (2-hydroxypropanesulfonic acid). In this product, an appropriate amount of base, such as sodium hydroxide, reacts with it according to a precise stoichiometric ratio to form part of the carboxyl group into a sodium salt, and finally obtains piperazine-N, N' -bis (2-hydroxypropanesulfonic acid) sesquinone salt. During the reaction process, temperature, reaction time, and concentration of reactants are all key factors and need to be carefully controlled. If the temperature is too high, or side reactions will occur, and the product will be impure; if the temperature is too low, the reaction will be slow and take
Another method uses nitrogen-containing heterocyclic derivatives as starting materials and is converted through a multi-step reaction. First, the heterocyclic ring is functionalized with specific substituents, and then hydrolyzed and sulfonated to construct a hydroxypropanesulfonic acid group at a specific position. Finally, through the reaction with the base, the degree of salt formation is precisely controlled to achieve the purpose of preparing sesquinone salt. Although this path is complicated, if the reaction conditions of each step are properly optimized, a high-purity product can also be obtained. During synthesis, there are strict requirements for the cleanliness of the reaction environment and the purity of the reagents used. A little carelessness will affect the quality of the product.