Products

Quinoline-8-Sulphonic Acid

Lingxian Chemical

Specifications

HS Code

595896

Chemical Formula C9H7NO3S
Molar Mass 209.22 g/mol
Appearance White to off - white solid
Solubility In Water Soluble
Melting Point 275 - 280 °C
Pka Value Around 2.45
Boiling Point Decomposes before boiling
Odor Odorless
Stability Stable under normal conditions
Packing & Storage
Packing Quinoline - 8 - Sulphonic Acid packaged in 500 - gram bottles for chemical use.
Storage Quinoline - 8 - Sulphonic Acid should be stored in a cool, dry, and well - ventilated area. Keep it away from heat, flames, and sources of ignition as it may be combustible. Store it in a tightly closed container to prevent moisture absorption and contamination, and segregate from incompatible substances such as strong oxidizing agents to avoid dangerous reactions.
Shipping Quinoline - 8 - Sulphonic Acid is shipped in tightly - sealed, corrosion - resistant containers. It's transported under conditions that prevent exposure to moisture and incompatible substances, in compliance with chemical shipping regulations.
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Quinoline-8-Sulphonic Acid
General Information
Historical Development
Quinoline-8-sulfonic acid is also a product of chemistry. The beginning of its appearance can be traced back to the past. At the beginning, the sages studied in the field of chemistry and gradually gained something. At that time, the method of experimentation was still simple, but the unremitting heart remained unchanged.
Over the years, the technology has improved. The craftsmen studied hard on the craftsmanship, hoping to obtain a purer product. Since the past, its use has also become more and more widespread. At first or only for academic research, after emerging in various industries. The road of medicine may be used as a supplement; the field of chemical industry also has its function.
The process of its development depends on the wisdom of the scholars and the hard work of the craftsmen. Over the years, this product has gradually emerged in the world, becoming one of the pearls in the field of chemistry. Today, it still has endless potential, waiting for our generation to continue exploring its secrets and exploring its new path.
Product Overview
Quinoline-8-sulfonic acid is also a special substance in chemistry. Its color, or crystalline state, is white and shiny, pure in quality and stable in nature. In the field of chemistry, it has a wide range of uses. It can be used as a test drug for chemical reactions, and it is an important angle for various reactions to help form new quality. It is also related to medical research. It is the basis for making good medicines, hoping to solve the source of diseases, and finding ways to cure diseases. Its nature is lively, it can respond to many things, and produce diverse products. In practice, it must follow regulations to ensure safety. Because of its nature, it is dangerous to touch, smell, or hurt the body. We chemical researchers must be cautious, study its nature, expand its use, for the prosperity of the chemical industry, do our best to explore its infinite wonders, in order to benefit the world.
Physical & Chemical Properties
The physical and chemical properties of quinoline-8-sulfonic acid can be studied. Looking at its shape, at room temperature, it may be in a crystalline state, with a color or nearly pure white, and a pure luster. In terms of its solubility, it has a certain solubility in common solvents such as water and alcohol. Water is the source of life, and quinoline-8-sulfonic acid is in it, which can gradually disperse and form a uniform state. Because of its molecular structure, it has groups that can interact with water molecules. And for alcohols, such as ethanol, there is also a phase-appropriate solubility, which may be related to the polarity of alcohols and intermolecular forces.
Its chemical properties are also considerable. The presence of sulfonic acid groups makes this compound acidic, and can neutralize with alkali substances to form corresponding salts. And under suitable conditions, some check points on the quinoline ring can be subjected to the action of reagents and substitution reactions, which is the basis for its use in the field of organic synthesis.
Technical Specifications & Labeling
Quinoline-8-sulfonic acid is a chemical that we have dedicated ourselves to researching. Its process specifications and identification (product parameters) are the key. Looking at the process specifications of this product, it needs to be controlled by a precise process. Since the selection of raw materials, it has gone through several rigorous processes. Each step needs to follow specific laws, such as the precise regulation of reaction temperature and duration, in order to obtain its good product.
As for the identification (product parameters), its purity must be clear, and the impurity content must be marked in detail, which is related to the quality of the product. The appearance, solubility and other characteristics should also be accurately recorded to facilitate users to understand its properties. In this way, strict adherence to process specifications and accurate identification (product parameters) can make the quality of quinoline-8-sulfonic acid stand out and fully demonstrate its capabilities in all applications.
Preparation Method
The method of making quinoline-8-sulfonic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. Take quinoline as the base, and put it into the reactor with an appropriate sulfation reagent, such as concentrated sulfuric acid or fuming sulfuric acid, according to the appropriate ratio. The temperature is controlled in a suitable range, generally about 150 to 200 degrees. This is the key, which is related to the reaction process and product purity. The reaction lasts for several hours, during which the sulfonic acid group is gradually connected to the eighth position of quinoline.
After the reaction is completed, it is neutralized, separated and purified. The excess acid is neutralized with alkaline substances, followed by extraction and crystallization, etc., to obtain pure quinoline-8-sulfonic acid. The catalytic mechanism is the activity of lysine, promoting the addition of sulfonic acid groups smoothly. This process has been optimized by many experiments and is now mature, which can provide a reliable method for related production and obtain high-quality products.
Chemical Reactions & Modifications
Nowadays, the research on Quinoline-8-Sulphonic Acid is very important for the chemical reaction and modification. The reaction of this compound can be explored in many ways. The method of the past may not be good, and it needs to be changed with new thinking.
Looking at the reaction, the change of conditions has a significant impact. Temperature, solvent, etc., are all key. If it can be adjusted properly, the reaction can be promoted to a beneficial direction. When modifying, it is also necessary to observe its structure in detail. According to its characteristics, new bases can be introduced, or its properties can be changed to obtain better quality.
Chemists should study the theory carefully and study the subtleties of the reaction. With a diligent and sensitive heart, seek its change and explore its novelty, so that this compound can be used in various fields of industry and scientific research to develop its growth, gain greater progress, and contribute to the prosperity of chemistry.
Synonyms & Product Names
Quinoline-8-sulfonic acid, also known as 8-quinoline sulfonic acid. Looking at its name, "quinoline" is the name of a class of nitrogen-containing heterocyclic compounds, whose rings have specific structures and properties. And "8-sulfonic acid" indicates that the sulfonic acid group is attached to the 8th position of the quinoline ring.
In the industry, or it is called 8-quinoline sulfonic acid, this is from the perspective of its preparation, emphasizing the process of sulfonation. It is also called by the trade name, but no matter what the name is, it refers to this thing. It is widely used in chemical, pharmaceutical and other fields, or as an intermediate, participating in the synthesis of many compounds; or due to its unique chemical properties, it plays a key role in some reactions. Different names identify this important chemical to facilitate industry communication and research.
Safety & Operational Standards
Safety and Operation Specifications for Quinoline-8-Sulfonic Acid Products
Quinoline-8-Sulfonic Acid is a substance often involved in our chemical research. In its experimental and production links, it strictly abides by safety and operation standards to ensure that everything goes smoothly, personnel are healthy, and the environment is not damaged.
The road to safety is the first protection. Anyone involved in this product must be equipped with protective equipment. Protective clothing can protect against its damage to the skin; goggles can prevent it from splashing into the eyes; masks can prevent its particles from entering the body to ensure smooth breathing. And the workplace must be well ventilated, so that the air is always fresh and harmful substances are difficult to accumulate.
When operating, there are also laws. When taking it, the action should be slow, the utensils should be clean and accurate, and its leakage should be avoided. Weighing is accurate, which lays the foundation for the follow-up reaction to be stable and accurate. In case of reaction, be familiar with its characteristics and conditions. Temperature, pressure, and reaction time are all key, and there is no error or accident. When heating, the temperature control is stable to prevent overheating and sudden boiling; stirring is uniform to make the reaction uniform.
Storage should not be taken lightly. Store in a cool and dry place, away from fire sources and direct sunlight. Classified storage, do not coexist with objects that are taboo, and prevent chemical reactions from happening. The logo is clear, and the ingredients, hazards, and dates are all detailed, which is easy to access and manage.
If you unfortunately encounter an accident, take emergency measures quickly. If the skin touches it, rinse it with a large amount of water quickly, and seek medical attention if necessary; if it enters the eye, it needs to be rinsed immediately, and seek medical treatment. When leaking, quickly cut off the source, and the surrounding control area should be cleaned up according to its nature. Don't panic.
The safety and operation specifications of quinoline-8-sulfonic acid are the cornerstone of chemistry research and production. We should keep it in mind, do it in reality, and use a scientific and rigorous state to ensure the safety and order of work, and urge graduate students to go before delivery.
Application Area
Quinoline-8-sulfonic acid is useful in many fields. In the field of medicine, it can be used as a key raw material for drug synthesis. With its unique chemical structure, it can help develop new therapeutic agents, or it can have unique therapeutic effects for specific diseases. In the chemical industry, it can participate in the preparation of a variety of fine chemicals to improve the performance and quality of products. In materials science, it can be used to improve some properties of materials, such as enhancing the stability and durability of materials. In addition, in scientific research and exploration, as an important chemical reagent, it can help scientists to deeply explore the mechanism of chemical reactions, open up new research directions, and provide a theoretical and practical basis for the development of various fields, showing a wide range of important application values.
Research & Development
In the field of chemical industry, new compounds are emerging. Among all kinds of compounds, Quinoline-8-Sulphonic Acid has recently attracted the attention of our researchers.
First obtained this thing, observe its properties, explore its structure, and understand its essence. Then study the reaction mechanism, hoping to understand its changes in various chemical reactions. During the experiment, observe its interaction with various reagents, and record the data in detail for accuracy.
As for the application, I also dedicated myself to studying. Or in the field of medicine, it can contribute to the research and development of new drugs; or in material science, help create materials with specific properties.
We should persevere and study hard, hoping to expand its application, promote the development of this product, and contribute to the progress of chemical industry, so that Quinoline-8-Sulphonic Acid will bloom in the future.
Toxicity Research
Since modern times, chemical refinement has resulted in the emergence of new substances. Today, there is Quinoline-8-Sulphonic Acid, which is used in chemical and pharmaceutical industries. However, the study of its toxicity is crucial.
We use scientific methods to explore its toxicity. After various experiments, observe its impact on living beings. In the experiment of mice, they were fed food containing this substance to observe the changes in their behavior and health.
At the beginning, the mice ate it, but no abnormality was seen. However, after eating it for a long time, the movement gradually slowed down, the coat lost its color, and the organs also showed signs of damage. It can be seen that although Quinoline-8-Sulphonic Acid can be used, it is toxic. When using it, be cautious and careful to prevent its harm and life, pollution to the environment. It must be studied in detail, and regulations must be used to protect its benefits and avoid its harm.
Future Prospects
Quinoline - 8 - Sulphonic Acid has shown its extraordinary quality in today's chemical research. Although we know it now, it is only the beginning of its appearance, but those who have studied it in our generation have seen the grand vision of its future development.
Its exquisite structure and unique properties may open up new paths for healing diseases in the field of medicine; or in the field of materials, it can help create strange materials to meet the needs of the future.
We should do our best to explore its subtleties and understand its laws of change. Looking forward to the future, we can use Quinoline-8-Sulphonic Acid as the basis to expand the new realm of chemical application, so that this material can be used for human well-being, blooming with sparkling light, so as to unfinished business and develop infinite possibilities in the future.
Frequently Asked Questions
What are the chemical properties of Quinoline-8-Sulphonic Acid?
Quinoline-8-sulfonic acid is an organic compound with many unique chemical properties.
Looking at its acidity, because it contains a sulfonic acid group (-SO-H), the sulfur atom in this group has strong electron absorption, which causes the electron cloud of oxygen-hydrogen bonds to be biased towards the oxygen atom, making the hydrogen atom easy to dissociate. Therefore, quinoline-8-sulfonic acid is acidic and can partially ionize hydrogen ions in water, showing the general properties of acids, such as neutralization with bases to generate corresponding salts and water.
In terms of solubility, the sulfonic acid group is a hydrophilic group, and the quinoline ring has a certain hydrophobicity. Overall, quinoline-8-sulfonic acid has a certain solubility in water, and with the increase of temperature, the solubility may increase; in polar organic solvents, it also has good solubility.
When it comes to reactivity, the sulfonic acid group can participate in a variety of substitution reactions. If under suitable conditions, the sulfonic acid group can be replaced by other groups, such as with nucleophiles. The nucleophilic reagent attacks the sulfur atom in the sulfonic acid group, and the sulfonic acid group leaves to realize group substitution, providing a variety of possibilities for organic synthesis. The quinoline ring is also reactive, and its nitrogen atom can provide lone pairs of electrons, participate in the electrophilic substitution reaction, and introduce other functional groups into the ring.
Furthermore, quinoline-8-sulfonic acid has certain stability. Under normal temperature and pressure, if there are no special conditions, its chemical properties are relatively stable, and it is not easy to spontaneously decompose or other violent reactions. However, under extreme conditions such as high temperature, strong acid, strong base or strong oxidant, its structure may change, triggering decomposition or other chemical reactions.
In summary, quinoline-8-sulfonic acid has unique chemical properties and has important application value in organic synthesis, pharmaceutical chemistry and other fields.
What are the physical properties of Quinoline-8-Sulphonic Acid?
Quinoline-8-sulfonic acid is one of the organic compounds. Its physical properties are quite specific, let me tell you in detail.
Looking at its properties, under room temperature and pressure, quinoline-8-sulfonic acid often takes the form of a white to light yellow crystalline powder. This form is easy to store and use, and in many chemical operations, because of its powdery form, it is easier to mix evenly with other substances and participate in various chemical reactions.
When it comes to solubility, this substance is soluble in water. For water, the solvent of all things, quinoline-8-sulfonic acid is soluble in water, which is a major characteristic. This solubility allows it to be fully dispersed in the reaction of the aqueous solution system, providing convenience for the smooth progress of the reaction. And after it dissolves in water, it can be uniformly distributed in the form of ions or molecules, which is conducive to the occurrence of various ionic reactions or molecular interactions.
Furthermore, the melting point is also one of its important physical properties. Quinoline-8-sulfonic acid has a specific melting point, and this melting point value provides a key basis for the identification and purification of this substance. In the purification operation of chemical experiments, according to its melting point characteristics, by controlling the temperature, quinoline-8-sulfonic acid can be separated from impurities to obtain high-purity products.
In addition, its density is also fixed. The characteristics of density are crucial in operations involving the relationship between the mass and volume of a substance. For example, when formulating a solution of a specific concentration, knowing its density can accurately calculate the amount of the required substance to ensure the accuracy and reproducibility of the experiment.
Looking at its smell, although it does not have a strong pungent or special odor, it also has its own unique smell. Although this smell is weak, it is also part of its physical properties. In some specific analysis and identification scenarios, it may be used as a basis for auxiliary judgment.
In summary, the physical properties of quinoline-8-sulfonic acids, from morphology, solubility, melting point, density to odor, etc., are of great significance in many fields such as chemical research and industrial production.
What are the applications of Quinoline-8-Sulphonic Acid?
Quinoline-8-sulfonic acid is used in various fields. In the field of medicine, it is an important organic synthesis intermediate. It can be used to create many drugs. Due to its unique structure, it can participate in various chemical reactions and help build complex drug molecular structures to achieve specific pharmacological effects.
In the dye industry, it also plays a key role. It can be used as a raw material for the synthesis of special dyes. Due to its own chemical properties, it can give dyes a unique color and good dyeing properties, making the fabric dyeing effect better and lasting.
In the field of materials science, quinoline-8-sulfonic acid can be used to prepare functional materials. With its chemical activity, it can modify the surface of materials, improve the physical and chemical properties of materials, such as improving the hydrophilicity and corrosion resistance of materials, and then broaden the application scenarios of materials.
Furthermore, in the field of analytical chemistry, it can act as an analytical reagent. Because it can react specifically with specific metal ions or compounds, it can realize qualitative or quantitative analysis of related substances, and play an important role in environmental monitoring, food safety testing, etc.
What is the preparation method of Quinoline-8-Sulphonic Acid?
The preparation method of quinoline-8-sulfonic acid has been known for a long time. In the past, the preparation was based on quinoline first, which was the key thing. Quinoline was placed in a special vessel, supplemented by an appropriate catalyst, which needed to be carefully selected to meet the needs of the reaction. And the reaction environment was also important, and the temperature and humidity needed to be precisely controlled, just like adjusting the strings of the piano, without a millimeter difference.
Then, slowly adding fuming sulfuric acid, this process must be cautious, like walking on thin ice in the abyss. The amount of sulfuric acid and the rate of addition are all about success or failure. When adding, it must be constantly stirred to make the two fully blend, just like water milk. The speed of stirring is also fixed. If it is too fast, it is easy to cause overreaction, and if it is too slow, the fusion will be poor.
When the reaction occurs, observe its changes, such as the change of celestial phenomena. Wait for the reaction to reach the right moment and stop. Later, the product is separated from the mixture by subtle methods, either by extraction or by distillation, depending on the situation. After separation, purification is carried out to remove impurities and make the product pure and flawless, such as the removal of flaws in good jade.
The method used for purification, or recrystallization, or chromatographic separation. When recrystallization, choose a suitable solvent, dissolve it at high temperature, and crystallize it at low temperature. The precipitated crystal is the pure substance of quinoline-8-sulfonic acid. Chromatographic separation achieves the purpose of purification through the difference between adsorption and desorption of different substances.
This preparation method is interlocking and careful step by step to obtain the required quinoline-8-sulfonic acid.
What are some common derivatives of Quinoline-8-Sulphonic Acid?
Quinoline-8-sulfonic acid is an important organic compound that has applications in many fields, and its common derivatives are quite diverse.
One is 8-hydroxyquinoline-5-sulfonic acid, which has unique chemical properties due to the presence of hydroxyl groups and sulfonic acid groups on the quinoline ring. Hydroxyl groups can participate in the formation of hydrogen bonds, and sulfonic acid groups give it good water solubility. In analytical chemistry, it is often used as a metal ion complexing agent, which can form stable complexes with various metal ions such as copper ions and aluminum ions. With this property, it can be used for qualitative and quantitative analysis of metal ions. In some drug synthesis, it is also a key intermediate, introducing specific structures to drug molecules to change drug solubility, stability and biological activity.
The second is 8-aminoquinoline-5-sulfonic acid, and the introduction of amino groups enriches the chemical properties of the derivatives. Amino groups are basic and can react with acids, which is an important reaction check point in organic synthesis. In the dye industry, they can be used as raw materials for the synthesis of new dyes. By reacting with different groups, a variety of conjugated systems can be constructed, thereby endowing dyes with unique colors and properties. In biochemical research, they can be modified to label biomolecules and assist in biomolecular detection and analysis.
The other is 8-haloquinoline-5-sulfonic acid. The presence of halogen atoms (such as chlorine, bromine, etc.) significantly affects the reactivity and physical properties of the derivatives. Halogen atoms can participate in nucleophilic substitution reactions and provide various pathways for molecular modification. In the field of materials science, it can be used to prepare functional materials, such as polymer materials modified by haloquinoline sulfonic acid derivatives, which may have special electrical and optical properties and may have application prospects in electronic devices, optical sensors, etc.