What is the chemical structure of (R) - (+) -1-Phenylethane Sulfonic Acid?
(R ) - (+) - 1 -phenylethanesulfonic acid, the chemical structure of which is also the analysis. This compound contains a benzene ring. The benzene ring is a planar ring structure composed of six carbon atoms with conjugated double bonds. It is aromatic and is an important structural unit in many reactions in organic chemistry. On the benzene ring, it is connected to an ethanesulfonic acid group. Ethane is a saturated hydrocarbon group containing two carbon atoms, and the carbon and carbon are connected by a single bond. Sulfonic acid group (-SO 🥰 H), which is connected to the terminal carbon atom of ethane. In the sulfonic acid group, the sulfur atom is connected by a double bond to two oxygen atoms, and the other is connected by a single bond to a hydroxyl group, and is bonded to the carbon of ethane. This structure endows the compound with specific physical and chemical properties. The sulfonic acid group is strongly acidic, and hydrogen ions can be ionized in water, which makes the compound exhibit acidic characteristics. Its three-dimensional structure (R ) - (+) - , indicates that the compound is chiral, and its optical rotation is right-handed. This chiral structure is of great significance in the fields of medicinal chemistry because the enantiomers may have very different biological activities. (R ) - (+) - The chemical structure of 1-phenylethanesulfonic acid is composed of a benzene ring, ethane group and sulfonic acid group. Each part affects each other and jointly determines its unique chemical behavior and physical properties.
What are the main uses of (R) - (+) -1-Phenylethane Sulfonic Acid?
(R ) -(+) - 1 -phenylethane sulfonic acid, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a chiral auxiliary agent. With its chiral characteristics, it can guide the formation of products with a specific three-dimensional configuration, and help synthesize high-purity chiral compounds. It is of great significance in the field of medicinal chemistry. The activity of many drugs is closely related to the three-dimensional configuration. Using this substance as an auxiliary agent can accurately synthesize drug molecules with a specific configuration, improving the efficacy and safety of drugs.
Furthermore, in the field of analytical chemistry, it is also an important chiral resolution agent. When splitting racemate mixtures, diastereomers are formed with enantiomers. Due to differences in physical properties, such as solubility and boiling point, the two can be split by conventional separation methods, such as recrystallization and chromatographic separation, to obtain a single chiral compound, which lays the foundation for in-depth study of the properties and functions of chiral compounds.
In the field of catalysis, (R ) -(+) - 1 -phenylethanesulfonic acid can act as a chiral catalyst or participate in the construction of chiral catalytic systems. Its unique chiral environment can selectively activate substrate molecules, promote the reaction along a specific path, improve the reaction's enantioselectivity and catalytic efficiency, and play a key role in asymmetric catalytic reactions, promoting the development of green chemistry and efficient synthesis.
What are the physical properties of (R) - (+) -1-Phenylethane Sulfonic Acid?
(R ) -(+) - 1 -phenylethane sulfonic acid, its physical properties are particularly important. This compound is often in the shape of a white crystal, and it is pure and uniform in quality. Its melting point is quite high, about within a specific temperature range. This property makes it stable in a solid state at room temperature.
Solubility is also one of its remarkable properties. In water, its solubility is quite good, because its sulfonic acid group is hydrophilic, it can form hydrogen bonds with water molecules, so it can be uniformly dispersed in the aqueous phase. Organic solvents, such as ethanol and acetone, also have a certain solubility, but they vary depending on the polarity of the solvent. Solvents with similar polarity have relatively high solubility.
In addition, the density of (R ) -(+) - 1-phenylethanesulfonic acid is also a physical property characterization. Compared with common organic compounds, its density has its unique value, which is important for the separation, purification and measurement of practical applications.
Furthermore, its refractive index cannot be ignored. When light passes through this compound, the refraction angle presents a specific value, which can be used to identify the purity and structural characteristics of the substance, providing a key basis for analysis. All these physical properties lay the foundation for in-depth understanding and application of (R ) -(+) - 1-phenylethanesulfonic acid.
What is the preparation method of (R) - (+) -1-Phenylethane Sulfonic Acid?
The preparation method of (R ) - (+) - 1 -phenylethanesulfonic acid is an important topic in the field of chemical synthesis. There are many methods, one of which is described in detail below.
First take an appropriate amount of phenethane, which is the starting material. Place it in a reactor, use sulfuric acid as a sulfonation reagent, and initiate a sulfonation reaction under specific temperature and pressure conditions. The temperature should be controlled between hundreds of degrees Celsius, and the pressure should be maintained moderately to ensure the smooth progress of the reaction. The molar ratio of sulfuric acid to phenethane, when precisely adjusted according to the specific needs of the reaction, is usually within a certain ratio range, so that the reaction can be efficient and there are few side reactions.
During the reaction, the reaction process needs to be closely monitored, and the degree of reaction can be detected by means such as chromatographic analysis. When the reaction reaches the desired degree, the reaction mixture is cooled, and then the separation and purification steps are carried out.
When separating and purifying, first extract with an appropriate organic solvent to initially separate impurities. Then perform distillation to further purify the product according to the difference in the boiling point of each component. The temperature and pressure of the distillation process also need to be precisely controlled to obtain high-purity (R ) - (+) - 1-phenylethanesulfonic acid.
In addition, chiral synthesis can also be used. A chiral induction reagent is used to participate in the reaction to directly generate the target chiral product. This rule requires careful selection of chiral reagents and more stringent reaction conditions to ensure the realization of chiral selectivity. However, if this method is successfully implemented, products with high optical purity can be obtained, which is of great significance in fields such as pharmaceuticals that require extremely high product purity and chirality.
The above preparation methods have their own advantages and disadvantages. In practical applications, careful choices should be made according to specific needs and conditions.
What is the price range of (R) - (+) -1-Phenylethane Sulfonic Acid in the market?
I don't know the price range of (R) - (+) -1-phenylethane sulfonic acid on the market. This compound is not commonly available, and its price is determined by many factors.
First, the purity is deeply affected. If it is a high-purity product, suitable for fine chemical experiments or pharmaceuticals, its price must be high; if the purity is slightly inferior, it is only for general research basic use, and the price may be slightly lower.
Second, the source route is also related. If it is carefully prepared by a well-known large factory and strictly controlled by quality, the price may be high due to brand and quality assurance; if it comes from a small factory or the cost of the synthesis process is low, the price may be different.
Third, the market supply and demand situation is the key. If there is a sudden increase in demand and limited supply, if the demand for a particular new drug is suddenly increased, the price will rise; otherwise, if the supply exceeds the demand, the price may fall.
Then I checked the list of common chemical products and past transaction records, but the exact price range was not found. For details, you can consult chemical product suppliers, chemical reagent sales platforms, or professional chemical trading forums to get a more accurate price range.