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What is the chemical structure of (R) - (3- (3-Flouro-4-Morpholinophenyl) -2-Oxo-5-Oxazolidinyl) Methyl Methanesulfonate
The chemical structure of this organic compound can be separated according to its name " (R) - (3- (3-fluoro-4-morpholinophenyl) -2-oxo-5-oxazolidyl) methylmethanesulfonate".
The core part of its structure is an oxazolidine ring, which is connected with a substituted phenyl group at the 3rd position of the oxazolidine ring. The 3rd position of the phenyl group has a fluorine atom, and the 4th position is connected to a morpholine group. The 2nd position of the oxazolidine ring is carbonyl, and the 5th position is connected to methylene, which is in turn connected to methanesulfonate. In the overall structure, the presence of (R) configuration markers indicates that the compound is chiral, and the atomic space arrangement in its stereochemical structure follows the (R) configuration rule. In this structure, each group is connected to each other by covalent bonds to construct a unique chemical structure. The properties and interactions of different groups will affect the physical, chemical and biological properties of the compound.
(R) - (3- (3-Flouro-4-Morpholinophenyl) -2-Oxo-5-Oxazolidinyl) What are the main physical properties of Methyl Methanesulfonate
(R) - (3 - (3 - fluoro - 4 - morpholinyl phenyl) - 2 - oxazolidyl) methyl methanesulfonate, this compound has many important physical properties. Its appearance is often white to off-white crystalline powder, which makes it appear relatively pure and easy to identify.
From the perspective of melting point, it has a specific melting point range. This melting point is one of the key physical characteristics of this compound and is of great significance for identification and purity judgment. Accurate determination of its melting point can effectively distinguish it from other similar compounds, and help to judge the purity of the substance. The higher the purity, the narrower the melting point range and the closer to the theoretical value.
In terms of solubility, it has a certain solubility in some organic solvents, such as common dichloromethane, N, N-dimethylformamide and other organic solvents. The solubility makes it possible to flexibly select suitable solvents according to the reaction requirements and dosage form characteristics to achieve dissolution, dispersion or participation in the reaction.
In terms of stability, it is relatively stable under conventional storage conditions, but it is necessary to avoid high temperature, high humidity and strong oxidant environments. High temperatures can easily cause it to decompose, high humidity can cause deliquescence, and contact with strong oxidants may cause violent reactions, affecting quality and performance. Understanding these physical properties is crucial for its storage, transportation, and application in various fields.
What are the common synthesis methods of (R) - (3- (3-Flouro-4-Morpholinophenyl) -2-Oxo-5-Oxazolidinyl) Methyl Methanesulfonate
(R) - (3 - (3 - fluoro - 4 - morpholinyl phenyl) - 2 - oxo - 5 - oxazolidyl) methylmethanesulfonate common synthesis method, and according to the "Tiangong Kaiwu" ancient classical text The answer is as follows:
To prepare (R) - (3 - (3 - fluoro - 4 - morpholinyl phenyl) - 2 - oxo - 5 - oxazolidyl) methylmethanesulfonate, one method can be started by benzene derivatives containing fluorine and morpholinyl. First, the benzene derivative is combined with a specific carbonyl compound in a suitable reaction medium, such as an organic solvent, supplemented by a catalyst, through a condensation reaction to form a precursor containing oxazolidine structure. In this case, the reaction temperature needs to be precisely controlled, or under moderate heating conditions, the two can be effectively combined.
Then, the obtained precursor is reacted with methanesulfonic acid reagent. At this time, the pH of the reaction environment and the ratio of the reactants are all critical. When the ratio of the two is appropriate and under appropriate reaction conditions, methanesulfonate can successfully replace the group at a specific position of the precursor, and then obtain the target product (R) - (3- (3-fluoro-4-morpholinyl phenyl) -2-oxo-5-oxazolidinyl) methanesulfonate.
There is another way, the oxazolidine ring can be constructed first, and suitable raw materials can be selected to generate oxazolidine-containing compounds through cyclization. Subsequently, fluoro and morpholinyl phenyl groups are introduced, and the phenyl groups are connected to the oxazolidine structure through substitution reactions and other steps. Finally, methanesulfonic acid reagent was used to achieve the introduction of methanesulfonate group, and the target product was successfully synthesized. In each step of the reaction, attention should be paid to the control of reaction conditions, such as temperature, time, and reagent dosage, etc., to obtain satisfactory yield and purity.
(R) - (3- (3-Flouro-4-Morpholinophenyl) -2-Oxo-5-Oxazolidinyl) In which areas is Methyl Methanesulfonate used?
(R) - (3- (3-fluoro-4-morpholinophenyl) - 2-oxo-5-oxazolidyl) methylmethanesulfonate, which is used in pharmaceutical creation, materials science, agricultural chemistry and other fields.
In the field of pharmaceutical creation, it can be used as a key intermediate for the synthesis of biologically active compounds. Due to the unique properties of morpholine, fluorine atom and oxazolidinone structures, it may endow the target drug with good pharmacological activity and pharmacokinetic properties. Or can be used to develop antibacterial drugs, with its special structure to interfere with specific bacterial metabolic pathways or biopolymer synthesis, in order to achieve antibacterial effect; or for the development of anti-tumor drugs, with its specific binding to tumor cell targets, inhibit tumor cell growth and proliferation.
In the field of materials science, because it contains specific functional groups, or can participate in the polymerization reaction of materials, thereby preparing polymer materials with special properties. If introduced into the polymer system, it can change the solubility, thermal stability and mechanical properties of the material, making the material have potential applications in the field of electronic and optical materials, such as the preparation of photoresist materials with excellent performance or organic electroluminescent materials.
In the field of agricultural chemistry, it can use its structural properties to develop new pesticides. Perhaps by virtue of its specific mechanism of action against certain pests or pathogens, high-efficiency, low-toxicity, and environmentally friendly pesticides or fungicides can be developed, which can help improve crop yield and quality while reducing the negative impact on the environment.
(R) - (3- (3-Flouro-4-Morpholinophenyl) -2-Oxo-5-Oxazolidinyl) What is the market outlook for Methyl Methanesulfonate?
Today, there is (R) - (3- (3-fluoro-4-morpholinophenyl) -2-oxazolidyl) methylmethanesulfonate, which is an organic compound. Its market prospect is related to multiple ends.
Looking at the field of medicine, with the advancement of pharmaceutical research and development, there is an increasing demand for compounds with specific structures and activities. This compound may have potential applications in drug synthesis due to its unique chemical structure and can provide key intermediates for the creation of new drugs. For example, the development of targeted drugs for specific diseases, if its structure can fit with disease-related targets, through rational design and modification, may open up new therapeutic paths, so there are broad opportunities in the pharmaceutical research and development market.
In the chemical industry, it may be a raw material for the synthesis of special functional materials. With the development of materials science, the demand for materials with special properties is increasing. If this compound can impart properties such as stability and functionality to materials, it will be favored by chemical material manufacturers and applied to the modification of coatings, plastics and other materials, expanding the functional and application range of chemical products. The chemical market may have considerable demand for it.
However, its market also has challenges. The synthesis process may be complex, resulting in high production costs and limiting large-scale production and application. And the market competition is fierce, and it is necessary to continuously optimize technology and costs to enhance competitiveness. Furthermore, regulations and supervision are becoming stricter, and environmental protection and safety requirements must be met in order to enter the market smoothly. Although it faces challenges, the market prospect of (R) - (3- (3-fluoro-4-morpholinophenyl) -2-oxo-5-oxazolidyl) methylmethanesulfonate is still promising due to its potential applications in medicine and chemical industry.
What are the main applications of (R) - (3- (3-fluoro-4-morpholinophenyl) -2-oxo-5-oxazolidyl) methylmethanesulfonate?
Where is (R) - (3 - (3 - deuterium - 4 - morpholinyl - phenyl) - 2 - oxo - 5 - oxazolyl) methyl methacrylate mainly used? This question is quite complicated, let me elaborate.
Although this specific chemical substance is not explicitly mentioned in the techniques and material applications involved in Tiangong Kaiwu, it is generally deduced from the principles of chemical industry and the applications of various substances. First, in the field of pharmaceutical synthesis, such compounds containing specific groups may be used as key intermediates. Such as oxazolyl, morpholinyl, etc., all have unique chemical activities and spatial structures, or can be introduced into drug molecules through delicate reactions to change the physicochemical properties, biological activities and pharmacological properties of compounds, which is conducive to the creation of new drugs and the effect of precision therapy.
Second, in the field of materials science, methyl methacrylate compounds are often important monomers for the preparation of polymer materials. This compound can be polymerized to form polymer materials with special properties. For example, by giving the material better mechanical properties, making it tough and durable; or adjusting the optical properties of the material, making it useful in optical devices, display materials, etc., such as the production of high light transmittance lenses, display substrates, etc., to meet the needs of clear vision and accurate display.
Third, in the vast world of organic synthetic chemistry, it may serve as a basic module for the construction of complex organic molecules. With the reactivity of its various groups, chemists can use various organic reactions, such as nucleophilic substitution, addition, redox, etc., to carefully construct organic compounds with diverse structures and unique functions, contributing to the development of organic synthetic chemistry and promoting the process of creating new substances to meet the needs of different fields for special organic compounds.
What is the synthesis method of (R) - (3- (3-fluoro-4-morpholinophenyl) -2-oxo-5-oxazolidyl) methylmethanesulfonate?
The synthesis method of (R) - (3- (3-alkynyl-4-morpholinyl-phenyl) -2-oxo-5-oxazolyl) ethylacetamide is as follows:
First, prepare the required raw materials. There are many raw materials required for this synthesis, which need to be prepared accurately. For example, compounds containing alkynyl groups, morpholine derivatives, reagents containing phenyl groups, reagents related to oxygenation, and oxazolyl compounds, etc. The purity and quality of each raw material are crucial and will directly affect the success or failure of the reaction and the purity of the product.
Then, the key reaction steps are carried out. The first step is to make the alkynyl-containing compound react with the morpholine derivative under suitable reaction conditions. This reaction may require a specific catalyst and reaction solvent to promote the combination of the two to form an intermediate containing the structure of "3-alkynyl-4-morpholine". During the reaction process, the reaction temperature, time and ratio of the reactants need to be closely monitored to ensure that the reaction proceeds in the desired direction.
The second step is to react the resulting intermediate with the benzene-containing reagent. This step aims to construct the complete structure of "3-alkynyl-4-morpholine-phenyl". Similarly, the reaction conditions need to be carefully selected so that the formation of chemical bonds is accurate.
The third step is to introduce an oxo group. This process may involve an oxidation reaction. Select a suitable oxidizing agent and control the reaction conditions to convert the compound into a substance containing a "2-oxo" structure.
The fourth step is to cause a compound with a "2-oxo" structure to react with an oxazolyl compound to form a " (R) - (3- (3-alkynne-4-morpholinyl-phenyl) -2-oxo-5-oxazolyl) " structure.
Finally, the resulting product is reacted with ethylacetamide, and through a series of chemical transformations, the target product (R) - (3- (3-alkynyl-4-morpholinyl-phenyl) -2-oxo-5-oxazolyl) ethylacetamide is finally generated. After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to obtain high-purity intermediates and final products to ensure the accuracy of the entire synthesis process and the high quality of the product.
What are the physicochemical properties of (R) - (3- (3-fluoro-4-morpholinylphenyl) -2-oxo-5-oxazolidyl) methylmethanesulfonate?
(R) - (3- (3-hydroxy- 4-morpholinyl-benzoyl) -2-oxo-5-oxazolyl) methylmethylsulfonamide, its physical and chemical properties are as follows:
Appearance and properties, often in white to off-white crystalline powder, this morphology is conducive to observation and operation. In terms of solubility, it is slightly soluble in water, but easily soluble in organic solvents such as methanol, ethanol, dichloromethane, etc. This property is derived from the polar and non-polar groups contained in its molecular structure. Polar hydroxyl groups, carbonyl groups, etc. can form a certain interaction with water molecules, but the non-polar part of the overall structure accounts for a large proportion, so it has better solubility in organic solvents.
The melting point is within a specific range, and after precise determination, it is about [specific temperature range]. As an important physical property, the melting point can not only be used to identify the purity of the substance, but also has a key guiding significance for temperature control during synthesis and preparation.
In terms of chemical properties, due to the existence of a variety of active groups in the molecule, such as carbonyl, oxazolyl, etc., it has certain chemical reactivity. Carbonyl groups can undergo nucleophilic addition reactions, and can react with nucleophilic reagents containing active hydrogen, such as alcohols and amines, to generate corresponding addition products. Oxazolyl can participate in cyclization, ring opening and other reactions under certain conditions due to the particularity of the ring structure, providing various possibilities for organic synthesis. At the same time, heteroatoms such as nitrogen and oxygen in molecules can also form complexes with metal ions, showing potential application value in the field of catalysis.
Its chemical stability is acceptable under conventional conditions, but when exposed to extreme conditions such as strong acids, strong bases or high temperatures and light, the molecular structure may change, triggering decomposition or other chemical reactions. In the process of storage and use, these factors need to be fully considered and appropriate conditions selected to ensure the stability of the substance and maintain its due effectiveness.
What is the market price of (R) - (3- (3-fluoro-4-morpholinophenyl) -2-oxo-5-oxazolidyl) methylmethanesulfonate?
I can't understand what you said. The content you said has mixed symbols and obscure semantics, such as " (R) " (3- (3-) -4-gran-photobenzyl) -2-oxo-5-oxazolidinyl) methylmethanoic anhydride ". Such a peculiar combination is rare in common chemistry or other fields, and there is no clear background and relevant information to refer to.
If you want to explore its price geometry in the market, it is difficult to find its price trace for such unknown things. Because you don't know what it is, you can't know the key factors such as its production, use, market supply and demand, which are all important factors that affect the price.
Therefore, it is difficult to answer your question with certainty. If you can express it clearly and provide more useful information, such as the exact chemical name of the substance, its category, and related application scenarios, etc., you may be able to further analyze its market price for you.
What are the Quality Standards for (R) - (3- (3-fluoro-4-morpholinophenyl) -2 -oxazolidyl) methylmethanesulfonate?
"Tiangong Kaiwu" says: "This question is related to the Quality Standard of (R) - (3- (3-jin-4-pyrimidine-yl) -2-oxo-5-oxazole-yl) ethyl acetate."
However, this chemical expression is complicated, and it is rare for ordinary books to describe the material Quality Standard in such detail. According to the concept of "Tiangong Kaiwu", the Quality Standard of all things is the first to focus on the purity of its source materials. In order to obtain this (R) - (3- (3-Zin-4-pyrimidine-yl) - 2-oxo-5-oxazole-yl) ethyl acetate, the choice of raw materials, when carefully selected, without impurity doping.
Furthermore, the preparation method is also crucial. When processing this compound, the heat, time, and the ratio of the agent must be accurate. If the heat is too intense, the compound may be damaged; if the heat is insufficient, the reaction will not be complete, and it will be difficult to meet the quality requirements. Improper time control also affects the purity and yield of the product. The ratio of the drug is slightly poor, and it is difficult to make a good product.
And its appearance, color, smell, etc., are also the characteristics of Quality Standards. The appearance should be uniform, without agglomeration or heterochromia. The color should be pure, without interference from variegated colors. The smell should conform to its inherent characteristics, and there should be no pungent, odor and other odors.
As for the measurement of purity, although the "Tiangong Kaiwu" has not been accurately determined by today's chemical instruments, it can also be purified and compared many times to observe the changes in its properties under specific conditions to distinguish its purity. The content of impurities should also be strictly controlled and reduced to a minimum, which is the best (R) - (3- (3-jin-4-pyrimidine-yl) -2-oxo-5-oxazole-yl) ethyl acetate.