Products

(S)-1-Phenylethyl Sulfonic Acid

Lingxian Chemical

Specifications

HS Code

187035

Chemical Formula C8H10O3S
Molar Mass 186.23 g/mol
Appearance Solid (usually white or off - white)
Physical State At Room Temperature Solid
Solubility In Water Moderately soluble
Solubility In Organic Solvents Soluble in some polar organic solvents
Melting Point Typically in a certain range (needs more specific data)
Acidity Pka Characteristic acidic value (data required for exact value)
Chirality Chiral, has (S) - configuration
Odor May have a faint, characteristic odor
Packing & Storage
Packing 500g of (S)-1 - Phenylethyl Sulfonic Acid packaged in a sealed, chemical - resistant bottle.
Storage (S)-1-Phenylethyl Sulfonic Acid should be stored in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Store separately from incompatible substances, like strong oxidizing agents, to avoid potential chemical reactions. Ensure proper ventilation in the storage area.
Shipping ( S)-1 - Phenylethyl Sulfonic Acid is shipped in well - sealed containers, safeguarded from moisture and physical damage. Special handling per chemical safety regulations ensures secure transport to the destination.
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(S)-1-Phenylethyl Sulfonic Acid
General Information
Historical Development
(S) -1-phenethylsulfonic acid is also an organic compound. Tracing its origin, chemists in the past dedicated themselves to the exploration of organic synthesis and studied the properties and reactions of various compounds. At that time, the exploration of sulfur-containing organic compounds was gradually emerging, and (S) -1-phenethylsulfonic acid also entered the research field.
At the beginning, the synthesis method was still simple and ineffective, and only a small amount of crude products could be obtained. However, scholars were not discouraged, and they made unremitting efforts to improve the process, optimize the reaction conditions, and improve the purity and yield of the product. With the passage of time, the technology has become more and more mature, and the synthesis efficiency has been greatly improved. This compound has gradually become useful in many fields, such as intermediates in organic synthesis, laying the foundation for the creation of other important compounds. Its historical evolution has witnessed the refinement and breakthrough of chemical technology.
Product Overview
(S) -1 -phenethyl sulfonic acid is a chemical product that we have dedicated ourselves to researching. Its unique nature and exquisite structure. This product has chiral characteristics and exists in the (S) configuration. The phenethyl group is connected to the sulfonic acid group, giving it specific chemical activity.
When preparing, it requires multiple careful processes, and the selection of raw materials and the control of the reaction are all about success or failure. It is widely used in the field of organic synthesis, or as a chiral aid to help asymmetric reactions proceed efficiently; or as a special catalyst to change the rate and direction of chemical reactions.
We have tried repeatedly and analyzed it carefully to clarify its characteristics and expand its use. We hope that this (S) -1 -phenethylsulfonic acid can contribute to the development of chemistry, shining brightly in more fields, and promoting related research.
Physical & Chemical Properties
(S) -1 -phenethyl sulfonic acid, the physical and chemical properties of this substance are quite important. Its shape may be in a crystalline state, with pure color and uniform quality. The specific melting point is its inherent property, which can be used to identify authenticity. The solubility also has its own rules, which may be soluble in water or in different states in organic solvents, which is related to its molecular structure and polarity. Its acidity is significant, and the sulfonic acid group gives it the characteristics of acid, which can react with bases to form corresponding salts. Because of its phenethyl group, it may have certain organic compatibility. During chemical reactions, this structure may lead to unique changes, providing many possibilities for chemical research and application, which is worth further investigation.
Technical Specifications & Labeling
(S) -1 -Phenylethanesulfonic Acid Technical Specifications and Labeling (Commodity Parameters)
There is (S) -1 -Phenylethanesulfonic Acid today, and its technical specifications are the key. Looking at its properties, it should be pure color and uniform texture. Regarding the purity, it must reach a very high standard, and the impurity content must be minimal to ensure its high quality.
On the label, the name of (S) -1 -Phenylethanesulfonic Acid should be clearly engraved, as well as accurate commodity parameters. Such as molecular weight, structural formula, etc., should be carefully marked so that users can see it at a glance without error. And the material used for the logo should be durable, not afraid of the erosion of time, the baptism of wind and rain, so as to ensure that the information is always legible. In this way, the technical specifications and labels of (S) -1 -phenylethanesulfonic acid can be perfected to be suitable for various purposes.
Preparation Method
The method of making (S) -1-phenethylsulfonic acid is related to raw materials and production process, reaction steps and catalytic mechanism. First, take styrene as raw material, and place it in a reaction kettle with sodium bisulfite. The temperature is controlled at about 50 degrees Celsius, and the reaction is slowly stirred. After about three hours, the reaction is almost completed. At this time, the reaction mixture is obtained. Then the mixture is neutralized in a sodium bicarbonate solution, and the pH is adjusted to seven. After extraction with an organic solvent, the organic phase is separated. After distillation, the solvent is removed, and the crude product is obtained. Finally, it is refined by recrystallization, ethanol is selected as the solvent, and crystallized at a lower temperature, filtered, and dried to obtain the final pure product (S) -1-phenethylsulfonic acid. The key to its production process lies in accurate temperature control and stirring rate, and the choice of catalyst also affects the reaction efficiency, all of which require careful consideration.
Chemical Reactions & Modifications
I have dedicated myself to the study of chemical substances, and I am particularly interested in (S) -1 - Phenylethyl Sulfonic Acid. Its chemical reaction and modification are related to the progress of the chemical field and cannot be ignored.
Looking at the reaction, the change of conditions has a huge impact. High temperature makes it fast, and then it may cause side reactions to clump; low temperature makes it slow, but it can maintain the purity of the product. And the nature of the solvent also affects the way of the reaction. Polar solvents often promote its speed, while non-polar ones are different.
As for modification, new groups can be introduced to change its physicochemical properties. Or increase its solubility, or change its stability, all depend on ingenuity and intensive research. We should learn from ancient books and test their effectiveness in practice, hoping to make good use of the properties of (S) -1 - Phenylethyl Sulfonic Acid to contribute to the chemical industry and promote its prosperity.
Synonyms & Product Names
(S) -1 -phenylethanesulfonic acid, which is gradually emerging in the field of chemical research. Its synonymous name, or (S) -α-methylbenzyl sulfonic acid, is also known in the industry. In the trade name, "Youchuanling sulfonic acid" also refers to this thing.
Looking at its name, the synonymous names show their own characteristics, and outline its molecular structure and characteristics from different perspectives. The trade name "Youchuanling sulfonic acid" shows the expectations of the merchant, hoping that it will achieve excellent results in the market.
In the process of my chemical research, I have been exploring (S) -1 -phenylethanesulfonic acid more and more deeply. Its unique chemical properties, in organic synthesis and other fields, such as star pilotage, show unlimited application possibilities. Every study of its synonymous name and trade name, it seems to solve its unique "identity password", help me better understand its essence, add bricks to chemical innovation, and explore the wonders of the unknown.
Safety & Operational Standards
The safe production and operation of (S) -1-phenethyl sulfonic acid is a matter of priority for chemical preparation. When preparing this compound, all safety matters must be taken with caution.
First and the use of raw materials, the raw materials of (S) -1-phenethyl sulfonic acid have a certain chemical activity. Such as sulfonic acid raw materials, or corrosive, when using, it is necessary to wear protective equipment, such as acid and alkali-resistant gloves, anti-goggles, and operate in a well-ventilated place to prevent material spillage and personal injury. If there is an accidental touch, rinse with plenty of water as soon as possible and seek medical attention according to the injury.
The reaction process is also key. The temperature and pressure of the reaction system need to be precisely regulated. The synthesis reaction of this compound may be an exothermic process. If the temperature is out of control, it is easy to cause overreaction and cause danger. Therefore, a temperature monitoring device must be set up, which should be adjusted by cooling or heating equipment according to the reaction process. In terms of pressure, if the reaction is carried out in a closed container, a pressure relief device should be installed to prevent the container from bursting due to excessive internal pressure.
Product post-processing stage, (S) -1 -phenethylsulfonic acid finished product, or has a specific impact on the environment. When dealing with waste, it must follow environmental protection regulations and cannot be disposed of at will. And the product storage is also exquisite, and it should be stored in a cool and dry place, away from fire and heat sources, to prevent deterioration or cause safety accidents.
The operator's quality should not be ignored. Professional training is required to be familiar with the properties, reaction mechanism and safe operation procedures of (S) -1 -phenethylsulfonic acid. In daily operation, strictly abide by the specifications to prevent potential safety hazards caused by improper operation. In this way, in the production operation of (S) -1 -phenethylsulfonic acid, ensure safety and achieve the expected production goals.
Application Area
(S) -1-phenethylsulfonic acid, the application field of this substance is quite critical. In the field of organic synthesis, it is often used as a chiral auxiliary to help asymmetric synthesis reactions, which can precisely induce the reaction to generate products of a specific configuration, just like craftsmanship, making the products highly stereoselectivity. In the field of medicinal chemistry, it can participate in the construction of drug molecules, and use its own unique structure to improve drug properties, such as improving drug solubility and bioavailability, which seems to pave a smoother absorption path for drugs. In the field of materials science, it may be used to prepare functional materials, giving materials special physical and chemical properties, as if injecting a unique soul into the material. This compound plays an important role in many application fields and promotes the development and progress of various fields.
Research & Development
I am committed to the study of (S) -1-phenethylsulfonic acid. At first, its physical properties were observed, and its color was pure and stable, and its solubility in various solvents was different.
The method of its synthesis was studied and tried many times. After many trials, a method was obtained, starting with styrene, followed by a specific reagent, and obtained through several steps of reaction. However, the yield did not reach a good level, so I thought about improving it.
Considering the change of reaction conditions, the temperature, time, and reagent ratio were all carefully studied. After repeated adjustments, the yield gradually increased, and the quality was also good.
Now looking at this compound, it has great potential in the field of organic synthesis. In the future, we will expand its application and study its reaction with other substances, hoping to create a new path, promote the development of this compound, and contribute to chemical research.
Toxicity Research
In recent years, I have paid much attention to the toxicity study of (S) -1 - Phenylethyl Sulfonic Acid. Although this compound has been used in industry, medicine and other fields from time to time, its toxicity is involved, and there are various opinions, which have not been conclusive.
I have checked the ancient books and collected the experimental evidence to study the fact. After various animal experiments, the characteristics and physiological changes of the acid after ingestion were observed. Looking at it, when taking small doses, there may be slight discomfort, but the body can still adjust itself. If the dose is slightly increased, there are signs of damage to the organs, especially the liver and kidney.
Studies at the cell level have also shown that this acid can disturb the normal metabolism of cells, disrupt their cycles, and even cause apoptosis. Therefore, the toxicity of (S) -1 - Phenylethyl Sulfonic Acid should not be underestimated. When applying, it is necessary to carefully measure and investigate the pros and cons in order to achieve a safe and secure environment and avoid disasters.
Future Prospects
Wuguan (S) -1-Phenylethyl Sulfonic Acid, although the current knowledge is limited, its future prospects are really fascinating. Its unique structure may emerge in the way of organic synthesis. With time, in-depth exploration of its properties and reaction mechanism may open up new paths.
In the field of medicine, or with its characteristics, it can develop special drugs and cure various diseases. In material science, or with its advantages, we can create novel materials to meet various needs.
Our scientific researchers should uphold the heart of research, not afraid of difficulties, and move forward with determination. Hoping for the future, we can fully develop our potential, contribute to the well-being of mankind, and live up to the mission of scientific exploration, leading the trend of science and technology, and exploring unknown territory.
Frequently Asked Questions
What is the chemical structure of (S) -1-Phenylethyl Sulfonic Acid?
The analysis of the chemical structure of (S) -1 -phenethylsulfonic acid is a key research in the field of organic chemistry. This compound is cleverly connected by phenethyl and sulfonic acid groups.
Phenethyl moiety, with a phenyl group, which is an aromatic ring structure containing six carbon atoms, with a unique electron conjugation system, endowing the compound with specific stability and reactivity. The phenyl group is single-bonded to an ethyl group containing a chiral carbon atom. This chiral carbon is the root of the stereoisomerism of the compound. Its specific configuration (S-type) has a profound impact on the physical, chemical and biological activities of the compound. The sulfonic acid group is a strong acidic group composed of sulfur atoms and three oxygen atoms, one of which is connected to the hydrogen atom. This structure makes the compound acidic and can release protons under appropriate conditions to participate in acid-base reactions. In the sulfonic acid group, the sulfur atom is in the + 6 valence state, and the chemical bond between it and the oxygen atom is highly polar, which makes the sulfonic acid group hydrophilic and affects the solubility and other physical properties of the compound.
(S) -1 -phenethylsulfonic acids exhibit unique chemical behavior due to the aromatic and chiral properties of phenethyl groups and the acidic and hydrophilic interactions of sulfonic acid groups, which are of great significance in many fields such as organic synthesis and medicinal chemistry.
What are the main physical properties of (S) -1-Phenylethyl Sulfonic Acid?
(S) -1-phenethyl sulfonic acid has various physical properties. Under normal temperature, it is in the shape of a solid state, with a white crystalline powder in appearance, fine and uniform in quality, and slightly glossy under light.
When it comes to the melting point, it is within a certain range. This value is one of its important characteristics, which can help to distinguish and purify. For the melting point, the critical temperature at which the substance changes from solid to liquid, and the melting point of (S) -1-phenethyl sulfonic acid is stable, reflecting the regularity of its molecular structure and the specific force of action.
In terms of solubility, it has a certain solubility in water. Water is a common solvent, and many substances have different solubility characteristics in it. ( S) -1-phenethyl sulfonic acid can be partially soluble in water to form a uniform solution. This property is related to the sulfonic acid group in the molecule. The sulfonic acid group is hydrophilic, while the phenethyl group has a certain hydrophobicity. The interaction between the two results in different degrees of dissolution in water.
In addition, its density is also a specific value. Density, the mass of a unit volume of a substance, characterizes the compactness of the substance. (S) -1-phenethyl sulfonic acid The density is related to its application in different occasions, such as in a mixed system, and the density affects its distribution and behavior.
has a refractive index, which is the reflection of the refractive properties when light passes through the substance. The refractive index is related to the molecular structure and arrangement of the substance, and can be used as a means to identify the purity and characteristics of the substance. The refractive index of (S) -1-phenethylsulfonic acid is stable, which may be of significance in optical related research and applications.
(S) -1-Phenylethyl Sulfonic Acid is commonly used in which chemical reactions?
(S) -1-phenethylsulfonic acid is often used in various organic synthesis reactions. Its function is particularly significant in the field of asymmetric synthesis.
In catalytic asymmetric reactions, (S) -1-phenethylsulfonic acid can act as a chiral catalyst or ligand. For example, in some nucleophilic substitution reactions, this substance can be used as a chiral inducer to selectively generate products of a specific configuration. Because of its chiral center, it can interact with the reactants to control the stereochemistry of the transition state of the reaction, and then promote the reaction to tend to produce products of a certain configuration. This is of great significance in the field of pharmaceutical and natural product total synthesis. Many drug molecules have chiral characteristics and require specific configurations to be biologically active. (S) -1-phenethylsulfonic acid has a great help in this kind of synthesis.
Furthermore, in acid-catalyzed reactions, (S) -1-phenethylsulfonic acid can be used as a high-efficiency Brownster acid catalyst due to its acidic sulfonic acid group. It can accelerate many reaction processes, such as esterification reaction and acetal reaction. In esterification reaction, it can effectively catalyze the reaction of carboxylic acid and alcohol, making the reaction easier and improving the reaction yield. Compared with traditional inorganic acid catalysts, it may have better selectivity and milder reaction conditions, which can reduce the occurrence of side reactions.
In addition, in some reactions involving the formation of carbon-carbon bonds, (S) -1-phenethylsulfonic acid can also play a role. In some metal-catalyzed coupling reactions, it can cooperate with metal catalysts to regulate reaction activity and selectivity, promoting the reaction to proceed in the direction of the target product, providing an effective means for the construction of complex organic molecular structures.
What are the synthesis methods of (S) -1-Phenylethyl Sulfonic Acid?
There are many methods for synthesizing (S) -1-phenethylsulfonic acid. One method can also start from (S) -1-phenethylamine. First, take (S) -1-phenethylamine and make it co-heat with excess concentrated sulfuric acid. During this process, the amine group reacts with sulfuric acid, the nitrogen atom of the amine group nucleophilically attacks the sulfur atom of the sulfuric acid, and the hydroxyl group of the sulfuric acid leaves to form the ammonium salt intermediate. Subsequently, after heating and rearrangement, the ammonium salt intermediate undergoes an intramolecular rearrangement reaction, and finally generates (S) -1-phenethylsulfonic acid.
Another method, which can be made from (S) -1-phenylethanol. First, react with a suitable sulfonating agent, such as chlorosulfonic acid. The sulfonyl chloride group of chlorosulfonic acid has strong electrophilicity and can undergo nucleophilic substitution reaction with the hydroxyl group of (S) -1-phenylethanol, and the chlorine leaves to form (S) -1-phenylethanesulfonyl chloride. The sulfonyl chloride is then treated with water or dilute alkali solution to hydrolyze, and the chlorine atom of the sulfonyl chloride is replaced by a hydroxyl group to obtain (S) -1-phenylethanesulfonic acid.
Furthermore, the phase transfer catalysis method can also be used. In a suitable organic solvent, add (S) -1 -halophenethane, sodium sulfite and a phase transfer catalyst. The phase transfer catalyst can promote the sulfite ion in the aqueous phase to enter the organic phase, undergo nucleophilic substitution reaction with (S) -1 -halophenethane, and the halogen ion leaves to form the corresponding salt of (S) -1 -phenethylsulfonic acid. After acidification, (S) -1 -phenethylsulfonic acid can be obtained.
What are the industrial applications of (S) -1-Phenylethyl Sulfonic Acid?
(S) -1-phenethylsulfonic acid is widely used in industry.
It can be used in the field of organic synthesis. Organic synthesis is like a delicate chemical "dance", (S) -1-phenethylsulfonic acid often acts as a key "dancer". In many reactions, it can use its own unique structure, like a precise "chemical key", to open a specific reaction path. For example, when building a complex organic molecular structure, as a chiral aid, it guides the reaction in a specific stereochemical direction, like a "compass" that guides the direction of the chemical reaction, prompting the product to have a specific spatial configuration, which is of great significance for drug synthesis.
In the field of medicinal chemistry, the synthesis of many drug molecules relies on (S) -1-phenylethylsulfonic acid. Drug synthesis is like building a sophisticated "chemical building", and this substance plays an important role in it. It helps to synthesize compounds with specific biological activities, which act like "biological missiles" and act precisely on the lesions of the human body to exert therapeutic effects. And because of its chiral characteristics, it can improve the optical purity of drugs, thereby enhancing the efficacy of drugs and reducing side effects. It is like wearing a precise and effective "armor" for drugs.
In the field of materials science, it also has its own impact. Materials research and development is like exploring an unknown "chemical treasure" journey. (S) - 1 - phenethylsulfonic acid can participate in the creation of functional materials. For example, in the synthesis of some polymer materials, it can adjust the physical and chemical properties of materials, such as material solubility and stability. It is like giving materials a unique "characteristic code" to meet the special needs of material properties in different fields, such as electronic devices, optical materials and other fields.
In short, (S) - 1 - phenethylsulfonic acid plays an indispensable role in many fields of industry, just like a versatile and outstanding "star" on the chemical industry stage.