Sodium 1-Amino-4-({3-[(2-Hydroxyethyl)Sulfamoyl]-4,5-Dimethylphenyl}Amino)-9,10-Dioxo-9,10-Dihydroanthracene-2-Sulfonate

1-Amino-4- ({3- [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenyl} amino) -9,10-dioxo-9,10-dihydroanthracene-2-sulfonate sodium salt, this is a rather complex organic compound. Looking at its name, it can be seen that its structure is an exquisite combination of several parts.
The anthracycline structure belongs to its core structure, which is a dioxo state at positions 9 and 10, forming a part of 9,10-dioxo-9,10-dihydroanthracene. At the second position of anthracycline, there is a sulfonic acid group in the form of a sodium salt, which imparts certain water solubility and ionic properties to the compound.
At the fourth position of anthracycline, a complex substituent is connected. The substituent starts with an amino group and is then connected to a structure containing 3 - [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenyl. Specifically, the 3-position of the phenyl group is connected with [ (2-hydroxyethyl) aminosulfonyl]. In this aminosulfonyl group, the sulfonyl group is connected with 2-hydroxyethyl, and the 4 and 5 positions of the phenyl group are dimethyl substituted.
The structure of this compound is exquisitely designed, and the various partial groups interact with each other, or affect its physical, chemical and biological properties. Or it is hydrophilic due to the sulfonic acid group, while the phenyl part containing dimethyl and aminosulfonyl groups, etc., or affect its interaction and reactivity with other molecules. Such a complex structure has specific uses in the fields of organic synthesis, drug development, materials science, etc., or because of its unique properties.

1-Amino-4- ({3- [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenyl} amino) -9,10-dioxo-9,10-dihydroanthracene-2-sulfonate sodium salt, this is a rather complex organic compound. Its main uses are wide, and it can be used as a high-quality dye in the dyeing and weaving industry. Because of its unique structure, it can be firmly combined with fabric fibers, and the dyed color is bright and has excellent light resistance and washable fastness, making the fabric last for a long time and the color is still brilliant.
In the field of biochemical research, it can be used as a biological dye. By staining cells or biological tissues, researchers can clearly observe their structure and morphology with the help of a microscope, providing key support for exploring the mysteries of life and understanding the microscopic world in organisms.
It also has important uses in pharmaceutical chemistry. Due to its special chemical properties, it may participate in the process of drug synthesis, laying the foundation for the creation of new drugs; or it may play a role in drug analysis, helping to accurately determine the composition and content of drugs, ensuring the quality and efficacy of drugs.
In addition, in the field of materials science, it may be used as an additive to functional materials. After addition, it can improve some properties of materials, such as improving the stability of materials, enhancing their optical properties, etc., thereby expanding the application range of materials and meeting the special needs of materials in different fields.

1-Amino-4- {3- [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenylamino} -9,10-dioxo-9,10-dihydroanthracene-2-sulfonate sodium salt, this is a rather complex organic compound. Its physical and chemical properties are as follows:
Looking at its properties, it is either solid or powdery at room temperature and pressure, but because the molecular structure is rich in many polar groups, such as amino, hydroxy, sulfonyl and sodium sulfonate groups, it may have a certain hydrophilicity and may be quite soluble in water.
When it comes to the melting point, the melting point is quite high due to the formation of multiple hydrogen bonds within the molecule and the strong intermolecular forces. However, the exact melting point needs to be accurately determined by experiments, because different purity and crystallization conditions will affect it.
When it comes to stability, the molecular structure of this compound is relatively stable. However, in the environment of strong acid and strong base, the stability may be affected due to the reaction of amino groups, sulfonyl groups and sodium sulfonate groups with acid and base. Under high temperature, high humidity or light conditions, its structural changes also need to be considered.
In terms of solubility, in view of the existence of many polar groups, it may have good solubility in polar solvents such as water; in some polar organic solvents such as methanol and ethanol, or it can also be dissolved. However, in non-polar solvents such as n-hexane and toluene, the solubility may be poor.
In terms of spectral properties, due to the presence of conjugated systems in the molecule, absorption peaks appear in the ultraviolet-visible spectrum or at specific wavelengths, which can be used for qualitative and quantitative analysis. And different groups in the molecule will also exhibit characteristic absorption peaks in a specific wavenumber range in the infrared spectrum, which is helpful for the identification of structures.

To prepare 1-amino-4- ({3- [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenyl} amino) -9,10-dioxo-9,10-dihydroanthracene-2-sulfonate sodium salt, the method is as follows:
First take an appropriate amount of anthraquinone-2-sulfonic acid, place it in the reactor, add an appropriate amount of sodium hydroxide solution, warm it to a suitable temperature, so that it is fully dissolved, this is the first step, so that the anthraquinone-2-sulfonic acid is initially converted to facilitate subsequent reactions.
Then, slowly add 1-amino-4-bromoanthraquinone-2-sulfonic acid to it to control the addition speed while maintaining a stable temperature. This step is a key reaction step, and the two will undergo a substitution reaction to generate an intermediate product. The reaction process needs to be closely monitored. By specific detection methods, such as thin-layer chromatography, observe the reaction process. When the reaction reaches the desired level, that is, stop heating and allow the reaction system to cool naturally.
To cool to a certain extent, add an appropriate amount of 3- (amino sulfonyl) -4,5-dimethylaniline, heat up again, and add an appropriate amount of basic catalyst, such as sodium carbonate, to promote the reaction. The purpose of this step is to further react the intermediate product with 3- (aminosulfonyl) -4,5-dimethylaniline to form the precursor of the target product.
After the reaction is completed, transfer the reaction solution to another container, add an appropriate amount of ethanol, and perform the recrystallization operation. By slowly cooling, stirring, etc., the target product is precipitated in the form of crystals. After that, the crystals are collected by suction filtration with a Brinell funnel, and the crystals are washed with a small amount of cold ethanol to remove impurities.
Finally, place the resulting crystal in a vacuum drying oven, control the appropriate temperature and vacuum, and dry for a certain period of time to obtain a pure 1-amino-4- ({3- [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenyl} amino) -9,10-dioxo-9,10-dihydroanthracene-2-sulfonate sodium salt product. The whole process requires strict control of the reaction conditions and operation details to ensure the purity and yield of the product.

1-Amino-4- {3- [ (2-hydroxyethyl) aminosulfonyl] -4,5-dimethylphenylamino} -9,10-dioxo-9,10-dihydroanthracene-2-sulfonate sodium salt, this is a very important chemical in fine chemicals. During use, many precautions need to be kept in mind.
Bear the brunt, safety protection should not be underestimated. Because of its certain chemical activity, it is necessary to be fully armed and wear suitable protective equipment when exposed. For example, protective gloves should be selected to resist the corrosion of the chemical to prevent it from coming into contact with the skin, causing skin allergies or chemical burns. Protective glasses are also indispensable to prevent the substance from splashing into the eyes and causing serious damage to the eyes.
Furthermore, storage conditions are also critical. It should be placed in a dry, cool and well-ventilated place. Because it is sensitive to environmental factors, humid environments can easily cause deliquescence and deterioration, which affects the use effect. If the temperature is too high, it may cause chemical reactions and reduce its stability. Therefore, the ambient temperature and humidity should be strictly controlled during storage to ensure that its quality is not affected.
When using, it is extremely important to precisely control the dosage. This chemical is highly active, and too much or too little dosage can have a significant impact on the reaction or application effect. Before use, the appropriate dosage should be determined by accurate calculation and experiment according to the specific reaction or application requirements. And when configuring the solution, the operation must be rigorous, and the correct steps and proportions should be carried out to ensure the accurate concentration of the solution.
In addition, the chemical reaction conditions during use also need to be carefully controlled. Temperature, pH and other conditions will affect the reaction process and product properties. If the reaction temperature is too high, the reaction may be out of control; the pH is not suitable, or the reaction cannot be carried out or by-products are generated. Therefore, when using it, the reaction conditions should be strictly controlled according to its chemical characteristics to achieve the ideal use effect.
After use, properly dispose of the remaining substances and waste should not be sloppy. Do not discard it at will, because it may cause pollution to the environment. It is necessary to carry out harmless treatment or recycling in accordance with relevant environmental regulations to reduce the harm to the environment.