Sodium 2-Phenylindole-5-Sulfonate

Sodium + 2 - Phenylindole - 5 - Sulfonate is an organic compound. In terms of its name, it is composed of sodium (Sodium) ions and 2 - phenylindole - 5 - sulfonate.
In this compound, the 2 - phenylindole part contains the core structure of indole, and is connected to the phenyl group at the 2nd position, giving it specific aromatic properties and spatial structure. In the 5 - sulfonate part, the sulfonate group (-SO
) is hydrophilic, which can make this compound exhibit unique solubility and chemical properties in specific solvents.
In the field of organic synthesis, it may be used as an important intermediate. Due to the reactivity of the indole structure, it can participate in many reactions, such as electrophilic substitution reaction. Due to the difference in electron cloud density at different positions, other functional groups can be introduced on the indole ring or phenyl group under appropriate conditions, thereby constructing more complex organic molecules.
And because of its sulfonate group, in materials science, it may be used to prepare materials with special properties. For example, in some self-assembled systems, the hydrophilic sulfonate part can interact with other hydrophilic substances, while the hydrophobic indole and phenyl part can self-assemble to form a specific structure, thereby imparting unique surface properties or micromorphology to the material.
In the field of medicinal chemistry, the structure of this compound may provide ideas for drug development. Indole compounds are often biologically active. By modifying their structures, such as adjusting the substituents on phenyl groups or changing the properties of sulfonate parts, it is expected to develop drug molecules with specific pharmacological activities, such as inhibitors or modulators for certain specific targets.

Sodium 2-Phenylindole-5-Sulfonate, commonly known as sodium 2-phenylindole-5-sulfonate in Chinese, has a wide range of uses and is significant in many fields.
First, in the field of materials science, it is often used as a key intermediate in organic synthesis. Through a series of carefully designed chemical reactions, chemists can skillfully combine it with other compounds to create new materials with unique optical and electrical properties. For example, for the preparation of organic Light Emitting Diode (OLED) materials. OLED technology has developed rapidly in the display field in recent years. After ingenious chemical modification of sodium 2-phenylindole-5-sulfonate, it can become an important part of the OLED light-emitting layer material, endowing the device with excellent luminous efficiency and color stability, making the display screen clearer and brighter.
Second, in the field of biomedical research, it can act as a fluorescent probe. Due to its special structure, it can fluoresce under the excitation of specific wavelengths of light, and is highly sensitive to certain specific substances or environmental changes in living organisms. Scientists take advantage of this property and introduce it into biological systems. By observing the change of fluorescence signals, highly sensitive detection of biomolecules can be realized, such as the identification and tracking of specific proteins, nucleic acids and other biological macromolecules, which can help early diagnosis and treatment monitoring of diseases.
Third, in the field of dye industry, sodium 2-phenylindole-5-sulfonate can be used to synthesize new dyes because of its unique color and good dyeing properties. When used in textile, printing and dyeing industries, such dyes can not only make fabrics show a bright and long-lasting color, but also have good light resistance and washable fastness, meeting people's dual needs for textile beauty and durability.
Fourth, in the field of analytical chemistry, it can be used as an effective analytical reagent. In some chemical analysis methods, it is used for quantitative or qualitative analysis of target substances based on its specific reaction with specific substances and the characteristics of detectable signals. For example, in colorimetric analysis or fluorescence analysis experiments, the content of target components in samples is accurately determined by the change of signal intensity in the detection system, providing accurate data support for quality control in scientific research and industrial production.

Sodium 2 - Phenylindole - 5 - Sulfonate is an organic compound with unique physical properties. Its appearance is often solid or crystalline powder, which forms a regular lattice structure due to the interaction between molecules. The color may be white to off-white, and the color is pure. This is due to the characteristics of chromophore groups in the molecular structure, and does not contain a large number of conjugated systems that can cause significant color.
In terms of solubility, the compound exhibits a certain solubility in water. Because of its hydrophilicity, the intramolecular sulfonic acid group can be combined with water molecules through ion-dipole interaction, and the water molecules surround the ions to form a hydrated shell, which promotes their dissolution. However, in organic solvents such as ethanol and ether, the solubility may be limited. Due to the intermolecular force between the organic solvent molecule and the compound, it is difficult to match the intramolecular polar groups, and it is impossible to effectively overcome the intermolecular attractive force to achieve dissolution.
Melting point is also an important physical property. The specific melting point of this compound is a reflection of the strength of the intermolecular force. When heated, the vibration of the molecule acquiring energy intensifies. When the melting point is reached, the kinetic energy of the molecule is sufficient to overcome the lattice energy, the lattice structure disintegrates, and the substance changes from a solid state to a liquid state. The melting point depends on the molecular structure, such as the presence of benzene rings and indole rings, which increases the intermolecular van der Waals force and makes the melting point relatively high.
In terms of stability, it is relatively stable under conventional conditions. However, in case of strong oxidizing agent or reducing agent, a chemical reaction may occur. Due to the existence of indole ring and benzene ring in the molecule, it has a certain electron cloud density, which can attack the check point of electrophilic or nucleophilic reagents, thereby changing the molecular structure and affecting its physical properties.

Sodium-2-phenylindole-5-sulfonate, this material property is also very wonderful. Its properties are stable and mostly exist in a specific transformation environment. Under normal conditions, it is in a solid state, with pure and uniform color, or a white crystal appearance, or with a shimmering light, and it looks bright.
In terms of its solubility, it can be gradually dissolved in water, just like a sweet rain moistening the soil, slowly fusing, and its liquid is clear, or it shows a light shadow color. In alcohols, it also has the property of blending, but depending on the type of alcohol, the degree varies, or the speed or the speed, all follow the law of transformation. The reaction of
heat can be particularly studied. In case of mild heat, there is no major change, just like a static person. The intensification of heat, such as the pressure of water and fire, its quality begins to move, and the structure of molecules gradually changes, or cracking or combining, forming a new compound. This change also varies according to the degree of heat and the length of time. The subtlety cannot be known without careful observation.
On top of chemical activity, the sulfonate base has active properties and can react with many reagents. When it encounters a base, such as a guest and host, the ion translocates and forms a new salt, and its properties also change accordingly. With the acid pair, it also reacts, and the sulfonyl group may be attacked by the acid, causing the structure to shift, and the properties of the compound are then different from before.
And because it contains the part of phenyl indole, it has the rhyme of aromatic ring, which can be involved in the transformation of aromatics. In the field of organic synthesis, it is a usable material and helps to form other things. It adds color to the chemical industry. It is a treasure in the chemical industry. Those who need to study it carefully and make good use of it.

The method of preparing sodium and sodium 2-phenylindole-5-sulfonate relies on various chemical techniques. The first method is to start with 2-phenylindole, and through sulfonation, the sulfonic acid group is entered into the 5 position. Among them, concentrated sulfuric acid or fuming sulfuric acid is often used as a sulfonating agent, and the two are combined under appropriate temperature and pressure. When reacting, be careful to check the temperature and reaction time to prevent excessive sulfonation and the formation of impurities. After sulfonation, neutralize with alkali solution, such as sodium hydroxide solution, to obtain 2-phenylindole-5-sulfonate sodium.
There are other methods, or the structure of 2-phenylindole is modified with appropriate substituents first, so that when sulfonated, the sulfonic acid group is more likely to enter the 5 position and increase the selectivity of the reaction. Or use a phase transfer catalyst to help the reaction proceed smoothly between heterogeneous systems and improve the reaction rate and yield. There is also a method of electrochemical synthesis to achieve the purpose of sulfonation by electrode reaction, which may be green and efficient. In short, the synthesis of this compound requires careful selection of suitable methods according to the availability, cost, yield and purity of raw materials.