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What are the main uses of Sodium 3-Mercaptopropanesulphonate?
Sodium-3-mercaptopropanesulfonate has a wide range of uses. In the industrial field, it is often used in the electroplating industry. Covering it can optimize the quality of the electroplating layer, making the coating more uniform, dense and shiny. For example, in the nickel plating process, adding this substance can effectively improve the physical properties of the nickel layer, improve its corrosion resistance and aesthetics, and make the plated object more practical and ornamental.
In medicine, it also has important applications. It is a heavy metal antidote, which can combine with heavy metal ions such as mercury, lead, bismuth and other heavy metal ions in the body to form a stable and soluble complex, which can be excreted in urine to achieve the effect of detoxification. In the treatment of patients with heavy metal poisoning, it plays a key role in saving many lives.
Furthermore, it also has a place in the field of chemical synthesis. It is often used as an intermediate in organic synthesis and participates in the preparation of many organic compounds. With its unique chemical structure and activity, functional groups such as sulfhydryl groups and sulfonic acid groups can be introduced to expand the types and properties of organic compounds, providing more possibilities for the research and development and production of chemical products. From this perspective, sodium-3-mercaptopropanesulfonate is indispensable in many fields such as industry, medicine, and chemical industry, and has made great contributions to promoting the development of various industries.
What are the physical and chemical properties of Sodium 3-Mercaptopropanesulphonate
Sodium 3-Mercaptopropanesulphonate, the Chinese name is sodium 3-mercaptopropanesulfonate. The physical and chemical properties of this substance are as follows:
Its appearance is often white crystalline powder, and it looks fine and uniform. In terms of solubility, it is very soluble in water and quickly disperses in water, just like fine sand flowing in, and there is no trace for a while. Due to the appropriate force between water molecules and the molecules of this substance, it can be intermingled with each other.
In terms of stability, it is usually quite stable under normal conditions, but in the case of strong oxidants, its molecular structure is easily destroyed. Just like a peaceful situation is disturbed by external forces, and it is no longer calm. Strong oxidants have the ability to seize electrons, while sulfur atoms in sodium 3-mercaptopropanesulfonate molecules have lone pairs of electrons, which are easy to be plundered by strong oxidants and cause structural changes.
Its melting point is in a specific range, which can be known by accurate measurement. When the temperature gradually rises to the melting point, the substance gradually melts from solid to liquid state. During this process, the arrangement of molecules changes significantly, from an ordered and compact solid lattice to a relatively disordered and free-moving liquid state.
Its aqueous solution is slightly acidic, which is due to the weak ionization of some groups in the molecular structure in water and the release of hydrogen ions. Like throwing fine stones on a quiet lake, although the waves are slight, it changes the acid-base properties of water.
Furthermore, the substance has a certain degree of hygroscopicity. In a high humidity environment, it absorbs water like a sponge, which will absorb water vapor in the air, resulting in an increase in its own weight, appearance or moist state. This is an important physical and chemical property of Sodium 3 - Mercaptopropanesulphonate.
How Sodium 3-Mercaptopropanesulphonate Prepared
The method of preparing Sodium 3-Mercaptopropanesulphonate is not detailed in the ancient book "Tiangong Kaiwu", but it can be made according to the principles of chemical industry.
First, use sodium acrylate as the starting material. First take an appropriate amount of sodium acrylate and place it in the reactor. The kettle should be made of glass or stainless steel to prevent corrosion. Introduce hydrogen sulfide gas, this process needs to be carried out at a specific temperature and pressure. The temperature should be controlled between 40 and 60 degrees Celsius, and the pressure should be about 1 to 2 atmospheres. At the same time, add an appropriate amount of alkaline catalyst, such as sodium hydroxide solution, with a concentration of about 10% to 20%. Under the action of the catalyst, sodium propene sulfonate and hydrogen sulfide undergo an addition reaction. The reaction formula is: CH ³ = CHCH ³ SO < unk > Na + H ³ S → HSCH < unk > CH < unk > SO < unk > Na. The reaction lasts about 3 to 5 hours. During this period, stirring is required to make the reactants fully contact to promote the reaction.
After the reaction is completed, the reaction mixture is obtained. To purify the product, the unreacted hydrogen sulfide gas and part of the water are removed by vacuum distillation. Then, the remaining liquid is passed through an ion exchange resin column to remove impurity ions and purify the product. Finally, the resulting solution is concentrated and crystallized to obtain a white crystalline 3-mercaptopropane sulfonate solid.
Second, it can also be prepared from sodium 3-chloropropane sulfonate and sodium hydride. Take sodium 3-chloropropane sulfonate and sodium hydride according to a certain molar ratio, usually 1:1.2 to 1:1.5, place in the reaction vessel, add an appropriate amount of solvent, such as ethanol or water-ethanol mixed solvent. Heat the reaction system, the temperature is controlled at 50 to 70 degrees Celsius, and the reaction takes about 4 to 6 hours. The reaction principle is nucleophilic substitution reaction, in which the chlorine atom of sodium 3-chloropropane sulfonate is replaced by thiohydrogen ion to generate sodium 3-mercaptopropane sulfonate. After the reaction is completed, the sodium chloride precipitate is removed by filtration, the filtrate is distilled to remove the solvent, and then recrystallized to obtain a high-purity sodium 3-mercaptopropane sulfonate product.
What to pay attention to when using Sodium 3-Mercaptopropanesulphonate
When using sodium 3-mercaptopropane sulfonate, pay attention to the following general matters.
First, it is related to storage. This medicine should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, improper temperature and humidity may cause it to deteriorate, which in turn affects the efficacy of the medicine. If it is damp or heated, or triggers a chemical reaction, causing its active ingredients to change.
Second, the rules for use. Be sure to check the properties of the medicine before use. If you see any abnormalities in color, smell, shape, etc., do not use it. The use process should ensure that the appliance is clean and dry to prevent impurities from mixing and contaminating the medicine. Measure the required dose accurately, and do not increase or decrease it at will, so as not to affect the therapeutic effect or cause adverse reactions.
Third, be careful of compatibility. When using, pay attention to the contraindications of its compatibility with other drugs. Sodium 3-mercaptopropanesulfonate has unique chemical properties and can be mixed or interacted with certain drugs, or reduce the efficacy of drugs, or generate harmful substances. Therefore, when combined with other drugs, be sure to consult a professional first to ensure that there is no compatibility problem before use.
Fourth, be careful of operation. When operating this drug, it is advisable to take necessary protective measures. Because it contains sulfur groups, it may be irritating. Appropriate protective gloves and goggles should be worn to avoid drug contact with skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical attention as appropriate.
Fifth, the object of use and the scene are clear. It needs to be used accurately according to the condition and the doctor's instructions. Different diseases and different patients' constitutions have different reactions to drugs. Especially for special groups, such as pregnant women, children, and the elderly, it is necessary to carefully weigh the pros and cons when using, and strictly follow the doctor's instructions.
What is the price range of Sodium 3-Mercaptopropanesulphonate in the market?
The price range of sodium 3-mercaptopropanesulfonate sold in the market often varies for many reasons. Among them, the purity of the product is the key factor. If the purity is very high, the impurities are rare, and it meets the high standard testing specifications, the price will be higher; on the contrary, if the purity is slightly lower, the price will be relatively low. Furthermore, the relationship between supply and demand also affects the price. If the market demand for this product is strong, but the supply is insufficient, the price will rise; if the demand is weak and the supply is abundant, the price will tend to stabilize or decline. Different manufacturers will also make the price different. Well-known large manufacturers may have higher product prices than ordinary manufacturers due to mature technology and strict quality control.
In terms of common market conditions, sodium 3-mercaptopropane sulfonate with a purity of about 98% may range from a few hundred to several thousand yuan per kilogram. If the purity reaches 99% and above, the price per kilogram may exceed 5,000 yuan or even higher. For some ultra-high purity products required in the field of special fine chemicals, the price is even higher. However, if it is industrial grade, the purity is slightly lower, such as about 95%, and the price per kilogram may be in the range of several hundred yuan.
In addition, the amount of purchase also affects the price. For bulk purchases, due to the scale effect, the supplier may give certain discounts, and the unit price will be reduced; for small purchases, the price may be relatively high. And in different regions, due to different transportation costs and market competition, prices will also fluctuate. For example, where transportation is convenient and the chemical industry is concentrated, prices may be slightly lower due to competition; in remote areas, prices may be slightly higher due to increased transportation costs.