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What is the chemical structure of sodium (3Z) -6-amino-3- ({4- [ (E) - (4-aminophenyl) azo] -2-methoxy-5-methylphenyl} hydrazone) -4-oxo-3,4-dihydronaphthalene-2-sulfonate?
About (3Z) -6-hydroxy-3- {4- [ (E) - (4-hydroxybenzyl) methylene] -2 -methoxy-5-methylbenzyl} Choman-4-ketone-3,4-dihydro-2-oxo-2-phenylchromium Chemical Structure Analysis
Looking at this chemical name, its structure must be exquisite and complicated. ( 3Z) -6-Hydroxy-3- {4- [ (E) - (4-hydroxybenzyl) methylene] -2-methoxy-5-methylbenzyl} In this part, Choman-4-ketone is used as the parent nucleus, and the complex substituent is connected at 3 positions. It contains alkenyl (3Z) and benzyl related structures, and has hydroxyl groups at 6 positions.
The (3Z) configuration of alkenyl groups determines the spatial orientation and affects the intermolecular interaction. In the benzyl structure, 4-hydroxybenzyl is connected to methylene and is associated with the parent nucleus. Hydroxyl groups can involve hydrogen bonding and affect the physical and chemical properties of compounds. 2-methoxy and 5-methyl are based on benzyl groups, which change the distribution of electron clouds and affect the reactivity.
Looking again at the 4-keto-3,4-dihydro-2-oxo-2-phenylchromium moiety, 2-oxo-3,4-dihydro-2-oxo-2-phenylchromium moiety, the carbonyl group of 2-oxo-4-keto has electrophilicity and can participate in the reaction. 2-Phenylchromium is introduced, chromium metal ions are connected to phenyl groups, or molecules The π-π electron system of phenyl groups can be deposited with other molecules, which affects the crystal structure and solution behavior.
Overall, the structure of this compound fuses a variety of functional groups and special structural fragments, and the interaction of each part endows it with unique chemical and physical properties. It may have potential applications in materials science, medicinal chemistry and other fields. Due to its structural complexity, it is of great significance to study its properties and reactions.
What are the main uses of sodium (3Z) -6-amino-3- ({4- [ (E) - (4-aminophenyl) azo] -2-methoxy-5-methylphenyl} hydrazone) -4-oxo-3,4-dihydronaphthalene-2-sulfonate?
(3Z) -6-Hydroxy-3 - {4- [ (E) - (4-hydroxybenzyl) imine] -2 -methoxy-5-methylbenzyl} Semen-4-ketone-3,4-dihydro-2-naphthol bismuth, the main use of this substance involves many aspects.
In the field of pharmaceutical research and development, its structure contains a variety of active groups, or it has unique pharmacological activities. Groups such as hydroxyl and methoxy can interact with targets in vivo, or can be used to develop anti-tumor drugs, which play a role by affecting tumor cell proliferation and apoptosis-related signaling pathways; or can be developed as antibacterial drugs, interfering with bacterial cell wall synthesis, protein metabolism and other physiological processes.
In the field of materials science, the special structure of this compound endows it with certain optical and electrical properties. Or organic optoelectronic materials can be prepared for organic Light Emitting Diode (OLED), because the conjugated structure is conducive to electron transmission and luminescence, improving the luminous efficiency and stability of the device; it may also emerge in the field of sensor materials, with the ability to selectively identify specific substances, build highly sensitive sensors to detect environmental pollutants or biomarkers.
In organic synthetic chemistry, it can be used as a key intermediate. Its complex structure provides the basis for the synthesis of more complex and functional organic molecules. Through structural modification and derivatization, a series of organic compounds with different properties and uses are prepared, expanding the research scope and application field of organic synthetic chemistry.
What are the precautions for the use of (3Z) -6-amino-3- ({4- [ (E) - (4-aminophenyl) azo] -2-methoxy-5-methylphenyl} hydrazone) -4-oxo-3,4-dihydronaphthalene-2-sulfonate sodium?
When using (3Z) -6-hydroxy-3-{ 4- [ (E) - (4-hydroxy-benzyl) formaldehyde] -2-methoxy-5-methylbenzyl} indole-4-oxo-3,4-dihydroquinoline-2-carboxylate cobalt, pay attention to the following numbers:
First, it is related to the use of the drug. Be sure to use it according to the precise dosage. The utensils used should be clean and dry to prevent impurities from mixing and affecting the quality of the drug and subsequent reactions. In the process of taking the drug, it is necessary to avoid contact with the skin, eyes and other parts of the drug. If it is accidentally contacted, it should be washed with a large amount of water immediately, and further measures should be taken according to the actual situation.
Second, about the reaction conditions. The reaction conditions such as temperature, pH, and reaction time have a significant impact on the reaction process of the drug. The temperature should be strictly controlled. With the help of precise temperature control equipment, the temperature should be stabilized in a suitable range, and the temperature deviation or the reaction rate should be changed, and even by-products should be generated. The pH should also be finely adjusted, and acid-base indicators or pH meters can be used to accurately measure and regulate. At the same time, the reaction time should be strictly controlled. If the reaction is too short or the reaction is incomplete, if it is too long, it may cause other side reactions.
Third, for preservation. This medicine should be stored in a dry, cool and ventilated place, away from direct sunlight and humid environments. Some medicines are sensitive to light and heat, and improper storage or deterioration of the medicine will reduce their activity and efficacy. It should also be noted that they should be stored separately from other chemicals to prevent mutual reaction.
Fourth, safety protection is involved. Wear appropriate protective equipment during operation, such as laboratory clothes, gloves, protective glasses, etc. If toxic gases or fumes are generated during the reaction process, it is necessary to operate in a fume hood to ensure the safety of the experimental environment and avoid the inhalation of harmful gases into the body and endanger health.
Fifth, it is related to the experimental records. All data should be recorded in detail throughout the experiment, including drug dosage, reaction conditions, reaction phenomena, etc. Detailed records are convenient for subsequent analysis of results. If there are problems in the experiment, it will also help to trace and investigate the cause.
What is the production process of (3Z) -6-amino-3- ({4- [ (E) - (4-aminophenyl) azo] -2-methoxy-5-methylphenyl} hydrazone) -4-oxo-3,4-dihydronaphthalene-2-sulfonate sodium?
Process for the production of (3Z) -6-hydroxy-3- ({4- [ (E) - (4-hydroxybenzyl) formaldehyde] -2-methoxy-5-methylbenzyl} sulfur) -4-oxo-3,4-dihydrothiophene-2-cobalt carboxylate
(3Z) -6-hydroxy-3- ({4- [ (E) - (4-hydroxybenzyl) formaldehyde] -2-methoxy-5-methylbenzyl The production process of this compound is as follows:
Preparation of starting materials
Select 4-hydroxybenzaldehyde and 2-methoxy-5-methylthiophenol of appropriate purity as starting materials. Ensure that the quality of the raw materials is high and the impurity content is extremely low, so as not to affect the subsequent reaction process and product purity.
Key intermediates Synthesis
1. ** (E) - (4-hydroxybenzyl) formaldehyde Synthesis **: 4-hydroxybenzaldehyde and the corresponding reagents, according to a specific ratio, in a suitable organic solvent, under the condition of alkali catalysis, carry out condensation reaction. The reaction temperature needs to be precisely controlled in a certain range, and the reaction time needs to be strictly controlled. After the reaction is completed, pure (E) - (4-hydroxybenzyl) formaldehyde is obtained through extraction, washing, drying and other processes.
2. ** {4 - [ (E) - (4 - hydroxybenzyl) formaldehyde] - 2 - methoxy - 5 - methylbenzyl} sulfur synthesis **: The above obtained (E) - (4 - hydroxybenzyl) formaldehyde and 2 - methoxy - 5 - methylthiophenol are reacted in an organic solvent under the action of a specific catalyst. This process requires strict temperature, reaction time and catalyst dosage. After the reaction is completed, the target intermediate is obtained by separation and purification.
Synthesis of the target product
Cyclization of {4- [ (E) - (4-hydroxybenzyl) formaldehyde] -2-methoxy-5-methylbenzyl} sulfur with compounds containing hydroxyl groups and other related groups under suitable reaction conditions to generate (3Z) -6-hydroxy-3- ({4- [ (E) - (4-hydroxybenzyl) formaldehyde] -2-methoxy-5-methylbenzyl} sulfur) -4-oxo-3,4 - Dihydrothiophene-2-carboxylic acid. Subsequently, it is reacted with cobalt salt in an appropriate solvent at a certain temperature and pH to form (3Z) -6-hydroxy-3- ({4- [ (E) - (4-hydroxy benzyl) formaldehyde] -2-methoxy-5-methylbenzyl} sulfur) -4-oxo-3,4-dihydrothiophene-2-carboxylic cobalt. The crude product obtained by the reaction of purification and refining
is further purified by column chromatography and recrystallization. A suitable solvent system was selected for recrystallization to remove impurities and improve the purity of the product. Finally, after drying treatment, a high-purity (3Z) -6-hydroxy-3- ({4- [ (E) - (4-hydroxybenzyl) formaldehyde] -2-methoxy-5-methylbenzyl} sulfur) -4-oxo-3,4-dihydrothiophene-2-cobalt carboxylate finished product was obtained.
What is the market prospect of sodium (3Z) -6-amino-3- ({4- [ (E) - (4-aminophenyl) azo] -2-methoxy-5-methylphenyl} hydrazone) -4-oxo-3,4-dihydronaphthalene-2-sulfonate?
The scene of the pharmaceutical market
Wuguan (3Z) - 6-hydroxy-3 - {4 - [ (E) - (4-hydroxybenzyl) formaldehyde] - 2-methoxy-5-methylbenzyl} naphthalene - 4-oxo-3,4-dihydrocouscous-2-cobalt carboxylate The city scene is full of thoughts, as if you are in an ancient and mysterious picture.
This medicine is in the market, and its scenery is quite unique. In the market, drug merchants are like weaving, all seeking this good medicine. Everyone looks attentive, or inquires about the price, or examines the quality of the medicine. This medicine has attracted people from all walks of life because of its unique effect.
The presentation of the medicine is either placed in an exquisite box or displayed on the case. Its color and texture are all the attention of everyone. The expert can distinguish the good and bad at a glance, and can know the authenticity and quality of the medicine with the touch of his fingertips and the sniff of his nose.
And the people around him include doctors in robes and drug dealers with bags. The doctor seeks this medicine to relieve the pain of the patient; the drug dealer seeks this medicine for the prosperity of survival. Everyone around the medicine, talking or arguing, their voices intertwined, as if it was a unique movement.
The atmosphere of the medicine market is not only a strict examination of the quality of the medicine, but also an enthusiastic transaction. The sun shines on the medicine, which seems to add a bit of mystery to it. The scene of the medicine market is like a vivid folk painting, showing people's emphasis on medicine and their pursuit of health.