Sodium (4Z)-4-[2-(3-Methyl-5-Oxo-1-Phenyl-4,5-Dihydro-1H-Pyrazol-4-Yl)Hydrazinylidene]-3-Oxo-3,4-Dihydronaphthalene-1-Sulfonate

This is a description of the chemical substance, which is called (4Z) -4- [2 - (3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-yl) hydrazine fork] -3-oxo-3,4-dihydronaphthalene-1-sodium sulfonate. The chemical structure of this substance is quite complex, and it is formed by the interconnection of many chemical groups.
Prophylenaphthalene ring part, which is a fused double ring structure with specific stability and reactivity. In the specific position of the naphthalene ring, there is a sodium sulfonate group, which imparts a certain hydrophilicity to the molecule, which can make the substance more soluble and dispersed in aqueous solution.
Looking at the pyrazole ring, this five-membered heterocyclic structure contains nitrogen atoms, which endows the molecule with unique electronic properties and biological activities. On the pyrazole ring, there is a methyl substitution at 3-position, an oxo-group at 5-position, and a phenyl group at 1-position. These substituents affect the electron cloud distribution and spatial structure of the pyrazole ring.
Between the naphthalene ring and the pyrazole ring, it is connected by a specific connection method to form a unique conjugated system, which has an important impact on the physical and chemical properties and possible biological activities of the molecule. This structure also contains many double bonds, carbonyl groups and other functional groups, and the interaction of each functional group makes the substance have specific reactivity and potential application value.
The various parts of this chemical structure cooperate with each other to form a whole, which determines the unique properties and potential uses of the substance in chemical reactions, materials science, drug development and other fields.

(4Z) -4- [2- (3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-yl) hydrazine fork] -3-oxo-3,4-dihydronaphthalene-1-sulfonate sodium, this compound has important uses in many fields.
In the field of medicine, it can be used as a lead compound. Due to the potential biological activity of pyrazole and sodium naphthalene sulfonate in the structure of this compound, it can bind to specific targets in vivo. For example, by interacting with specific enzymes or receptors, it can regulate physiological processes, or be used to develop new anti-inflammatory and anti-tumor drugs. Studies have shown that compounds with similar structures have inhibitory effects on the expression of certain inflammatory factors, providing new ideas for the treatment of inflammatory diseases.
In the field of materials science, it may have unique optical and electrical properties. The naphthalene ring structure gives it a certain conjugate system, or makes the compound stand out in photoelectric materials, such as in organic Light Emitting Diode (OLED), because it can achieve specific light emission, which can optimize the display effect; or in solar cells, which can improve the photoelectric conversion efficiency.
In analytical chemistry, it can be used as an analytical reagent. Due to its unique structure, it can react with certain substances under specific conditions, and can be used for qualitative and quantitative analysis of specific compounds. For example, stable complexes are formed with metal ions, and the content of metal ions is determined by spectral analysis, which is useful in environmental monitoring, food testing, and other aspects.

"Tiangong Kaiwu" is an ancient scientific and technological masterpiece in our country, but the inquiry is " (4Z) -4- [2- (3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-yl) hydrazinyl] -3-oxo-3,4-dihydronaphthalene-1-sodium sulfonate", which is a fine organic compound named by modern chemistry, which cannot be involved in "Tiangong Kaiwu" at that time.
Physical properties of this compound, generally speaking, it is mostly solid. Because of its sodium sulfonate group, it may have a certain solubility in water. Due to the strong hydrophilicity of sulfonate ions, it can form hydrogen bonds with water molecules, which is conducive to dissolution. The melting point may vary depending on the intermolecular forces and crystal structure. There are many conjugated structures in the molecule, such as naphthalene rings and pyrazole rings, or the intermolecular forces are enhanced, resulting in a higher melting point.
In appearance, in view of the presence of many aromatic rings and chromophore in the molecule, or white to light yellow solids, the specific color is also affected by impurities or crystal forms. Its density is related to the relative molecular weight and the degree of molecular packing. Due to its complex structure and containing a variety of atoms and groups, the relative molecular mass is large, and when the molecules are packed tightly, the density may be higher.
In terms of stability, the nitrogen atom of the intramolecular pyrazole ring can form hydrogen bonds with adjacent carbonyl groups to enhance molecular stability. However, its stability to light, heat and acid-base environments still needs to be experimentally investigated in detail. In the case of strong acids and bases, sodium sulfonate groups or hydrolysis, the structures of pyrazole rings and naphthalene rings may also change. When heated, the weak internal bond energy of the molecule may break down. Under light, the conjugated structure or the absorption of photon energy triggers photochemical reactions.

To prepare (4Z) - 4 - [2 - (3 - methyl - 5 - oxo - 1 - phenyl - 4,5 - dihydro - 1H - pyrazole - 4 - yl) hydrazine fork] - 3 - oxo - 3,4 - dihydronaphthalene - 1 - sodium sulfonate, the method is as follows:
First take an appropriate amount of 3 - methyl - 1 - phenyl - 5 - pyrazolone and place it in a clean reactor. In addition, a suitable solvent, such as anhydrous ethanol, is used to fully dissolve it to form a uniform solution. In this solution, slowly add hydrazine hydrate, and the dosage needs to be precisely controlled. It is better to have a slightly excessive stoichiometric ratio to promote the reaction energy to be more complete. After adding, heat up to a moderate temperature, about 80-90 degrees Celsius, and continue to stir the reaction at this temperature, so that the reaction can be fully reacted. Pay close attention to the reaction process during this period, which can be monitored by thin-layer chromatography and other means.
When the reaction is completed, cool the reaction solution to room temperature, at which time precipitation can be seen. Filtered through a Brinell funnel, the precipitate was collected and washed several times with cold ethanol to remove impurities, and then the resulting solid product was dried at low temperature in an oven to obtain 2- (3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-yl) hydrazine.
Take 3-oxo-3,4-dihydronaphthalene-1-sulfonic acid and dissolve it in a suitable solvent, such as dichloromethane. The 2 - (3 - methyl - 5 - oxo - 1 - phenyl - 4,5 - dihydro - 1H - pyrazole - 4 - yl) hydrazine prepared above is added to it, and an appropriate amount of catalyst, such as p-toluenesulfonic acid, is added to accelerate the reaction. Stir the reaction at room temperature, and constantly observe the change of the solution during the reaction.
When the reaction reaches the desired level, add an appropriate amount of sodium hydroxide solution to the reaction system, adjust the pH value to the basic range, and convert the product into sodium salt form. Subsequently, the solvent was removed by rotary evaporator, the residue was dissolved in water, and then extracted with an appropriate amount of organic solvent to remove unreacted impurities. The aqueous phase was taken, concentrated under reduced pressure, cooled to crystallize, and the precipitated crystal was (4Z) - 4 - [2 - (3 - methyl - 5 - oxo - 1 - phenyl - 4,5 - dihydro - 1H - pyrazole - 4 - yl) hydrazine] - 3 - oxo - 3,4 - dihydronaphthalene - 1 - sodium sulfonate. Finally, the crystals are filtered and collected, washed several times with deionized water, and dried at low temperature to obtain a pure product.

This is a compound named " (4Z) -4- [2- (3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-yl) hydrazine fork] -3-oxo-3,4-dihydronaphthalene-1-sodium sulfonate". During use, many matters need to be paid attention to.
First, safety protection must be comprehensive. The properties of this compound are unknown, or it may be potentially dangerous, such as toxicity and irritation. When operating, it is necessary to wear appropriate protective equipment, such as laboratory clothes, gloves, and goggles, to prevent skin contact and eye splashing. If you contact accidentally, rinse quickly with plenty of water and seek medical attention according to the specific situation.
Second, accurate weighing and access are essential. Because it may have a significant impact on subsequent reactions and experimental results, when using accurate weighing instruments, follow the specified dosage, and must not be increased or decreased at will, resulting in experimental deviations.
Third, storage conditions cannot be ignored. According to its physical and chemical properties, choose a suitable environment. It may be necessary to prevent moisture, light, and heat to prevent deterioration and decomposition, and to maintain its stability and activity.
Fourth, it is important to be familiar with the reaction characteristics. If it is used in a chemical reaction, when the reaction mechanism, conditions, rate, temperature, pH, reaction time and other factors are understood, the reaction will proceed as expected, and the purity and yield of the product will be improved.
Fifth, waste treatment should be carried out according to regulations. After use, the residue and reaction waste should not be discarded at will. When it is used according to the chemical waste treatment specifications, it should be collected and properly disposed of to avoid environmental pollution and human harm.
When this compound is used, safety, precise operation, suitable storage, familiarity with the reaction, and compliance with the treatment of waste are all key to ensure the smooth use process and achieve the desired purpose.