What is the chemical structure of Toluene-4-Sulfonic acid Thiophene-2-Yl-Ethylester?
Alas! The chemical structure of Toluene - 4 - Sulfonic acid Thiophene - 2 - Yl - Ethylester needs to be analyzed in detail. This name is composed of many parts, each referring to the structure of the molecule.
"Toluene - 4 - Sulfonic acid" means toluene - 4 - sulfonic acid. For toluene, there is an organic compound attached to the benzene ring. The sulfonic acid group (-SO 🥰 H) is attached to the 4th position of toluene, which is an important part of the molecule. The sulfonic acid group is acidic because its sulfur atom is connected with three oxygen atoms, one of which is connected to hydrogen and can ionize hydrogen ions.
"Thiophene-2-Yl-Ethylester", thiophene-2-yl-ethyl ester is also. Thiophene is a sulfur-containing five-membered heterocyclic compound, and its ring is aromatic. "2-Yl" indicates that the connection check point is at position 2 of the thiophene ring. For ethyl esters, that is, ester groups (-COO-), and the alkyl moiety of the ester group is ethyl (-CH < CH < CH >).
In summary, the chemical structure of Toluene-4-Sulfonic acid Thiophene-2-Yl-Ethylester is that the sulfonic acid group is connected to the sulfonic acid part of the toluene 4 position, and is connected to the thiophene 2 position through the ester group, and the other part of the ester group is ethyl. This structure makes it have some properties of toluene, thiophene and ester compounds, and may have unique uses in organic synthesis and related chemistry. In its structure, the benzene ring and thiophene ring endow the molecule with a certain conjugate system, which affects its electron cloud distribution and chemical activity; the acidity of the sulfonic acid group and the chemical activity of the ester group are also important properties of the compound.
What are the common physical properties of Toluene-4-Sulfonic acid Thiophene-2-Yl-Ethylester?
Toluene-4-thiophene-2-ethyl sulfonate is one of the organic compounds. Its common physical properties are quite important, and it is related to many chemical and scientific applications.
When it comes to appearance, this compound is often in the form of a white to light yellow crystalline powder, like fine frost and snow, or shimmering in sunlight, with a fine and uniform texture. It has a specific melting point, usually around [X] ° C. The stability of this melting point can be used as an important basis for judging the purity. When heated to this temperature, the substance gradually melts from a solid state to a liquid state, similar to the melting of ice and snow. The process is quite orderly and follows certain thermodynamic laws.
Furthermore, its solubility is also a key property. In organic solvents, such as common ethanol, acetone, etc., it exhibits good solubility and can be uniformly dispersed, just like salts dissolve in water to form a uniform solution system. This property is conducive to its use as a reactant or intermediate in organic synthesis reactions to participate in various chemical conversions. However, in water, its solubility is relatively limited, only slightly soluble, due to the role of hydrophobic groups in the molecular structure, making it difficult to fully affinity with water molecules.
In addition, the density of the compound also has a certain value, about [X] g/cm ³, which is of great significance for accurate measurement and in processes involving fluid dynamics, related to its sedimentation and dispersion in different media. Although its smell is not strong and pungent, it has a unique organic smell, which seems to be mixed with a special smell brought by some sulfur elements. During operation and use, attention should be paid to ventilation to prevent uncomfortable effects on the human respiratory tract.
The physical properties listed above, such as appearance, melting point, solubility, density and odor, are common and important properties of toluene-4-thiophene-2-ethyl sulfonate, and are indispensable factors in chemical production, organic synthesis and related scientific research.
Where is Toluene-4-Sulfonic acid Thiophene-2-Yl-Ethylester used?
Toluene-4-thiophene-2-ethyl sulfonate, this substance is useful in various fields.
In the field of pharmaceutical synthesis, it is often an important intermediate. The structural properties of Geiinthiophene and sulfonate can be used to construct complex drug molecular structures through various chemical reactions. Taking the development of an anti-cancer drug as an example, researchers skillfully used toluene-4-thiophene-2-ethyl sulfonate to successfully introduce key active groups through multi-step reactions, so that the prepared drug has a good inhibitory effect on cancer cells.
In the field of materials science, it also has applications. For example, when preparing special functional polymer materials, it is introduced into the polymer system as a modifier. Through this operation, the properties of the material can be effectively improved, such as improving the thermal stability of the material and enhancing its mechanical properties. The new material prepared by the scientific research team blends it with specific polymers can still maintain good physical properties in high temperature environments, providing new options for materials used in high temperature environments.
The field of organic synthesis is even more indispensable. It can participate in many organic reactions, such as nucleophilic substitution reactions, esterification reactions, etc. In the synthesis of organic compounds with special structures and functions, toluene-4-thiophene-2-ethyl sulfonate, as a reactant or catalyst, plays a key role in the synthesis of many novel and potentially valuable organic molecules.
What are the conventional methods for synthesizing Toluene-4-Sulfonic acid Thiophene-2-Yl-Ethylester?
There are several common methods for synthesizing toluene-4-sulfonate thiophene-2-ethyl ester.
First, thiophene-2-ethanol and toluene-4-sulfonyl chloride are used as raw materials. First place thiophene-2-ethanol in a suitable reaction vessel and add an appropriate amount of acid binding agent, such as triethylamine. Slowly add the solution of toluene-4-sulfonyl chloride dropwise under low temperature and stirring. Add it dropwise, warm it to an appropriate temperature, and continue to stir for several hours. After the reaction is completed, the reaction solution is washed with water to remove the unreacted raw materials and by-products, and then the product is extracted with an organic solvent. After drying and distillation, pure toluene-4-sulfonate thiophene-2-ethyl ester can be obtained. In this process, the acid binding agent can be combined with the hydrogen chloride generated by the reaction to promote the forward reaction, and low temperature dropwise addition can reduce the occurrence of side reactions.
Second, thiophene-2-ethanol is reacted with toluene-4-sulfonate anhydride. The two are placed in a reactor in a certain proportion, and an appropriate amount of catalyst, such as 4-dimethylaminopyridine (DMAP), is added. Under mild heating and stirring conditions, the reaction is carried out for a period of time. After the reaction is completed, the target product can also be obtained by similar separation and purification steps, such as washing with dilute acid and dilute alkali, extraction with organic solvents, distillation and refining, etc. In this reaction, DMAP can effectively catalyze the reaction of sulfonic anhydride and alcohol, improving the reaction rate and yield.
Third, thiophene-2-ethanol can be converted into the corresponding sodium alcohol first, and thiophene-2-ethanol can be obtained by reacting sodium metal or sodium hydride with thiophene-2-ethanol. Subsequently, the sodium alcohol is reacted with toluene-4-sulfonate. In an anhydrous organic solvent, such as anhydrous tetrahydrofuran, the reaction is carried out by heating and stirring. After the reaction is completed, regular separation operations, such as filtration to remove salt by-products, extraction, distillation, etc., finally obtain toluene-4-thiophene-2-ethyl sulfonate. In this way, the formation of sodium alcohol can enhance the nucleophilicity of the alcohol, which is conducive to the smooth progress of the nucleophilic substitution reaction with sulfonate.
What are the storage conditions for Toluene-4-Sulfonic acid Thiophene-2-Yl-Ethylester?
Toluene-4-thiophene-2-ethyl sulfonate, this is an organic compound. Its storage conditions are very critical, related to the stability and quality of this substance.
According to the concept of "Tiangong Kaiwu", everything needs to be properly stored. This compound should be stored in a cool and dry place. A cool place can slow the thermal movement of its molecules, preventing them from structural changes or chemical reactions caused by excessive temperature. If it is exposed to high temperature, it may cause decomposition and deterioration, which will damage its chemical properties.
A dry place is also indispensable. Moisture can easily cause many chemical changes, such as hydrolysis reactions. If the environment is humid, water molecules may interact with the compound, destroying its original chemical bonds, causing changes in its composition and properties.
And it should be placed in a place protected from light. Light is often the energy source of chemical reactions, or induces luminescent chemical reactions to change the structure of the compound. Therefore, storing in an opaque container can reduce the influence of light on it.
Furthermore, the storage place should be away from fire sources, oxidants, etc. This compound may be flammable, and it is easy to cause fire in case of fire, and the oxidant may also react violently with it, endangering safety.
Also pay attention to the material of the storage container. A material that does not chemically react with it, such as a specific glass or plastic container, should be selected to prevent the container from interacting with the compound and affecting its quality. In this way, toluene-4-sulfonate thiophene-2-ethyl ester can be properly stored to maintain its chemical stability.